JP2008528512A5 - - Google Patents
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- JP2008528512A5 JP2008528512A5 JP2007552375A JP2007552375A JP2008528512A5 JP 2008528512 A5 JP2008528512 A5 JP 2008528512A5 JP 2007552375 A JP2007552375 A JP 2007552375A JP 2007552375 A JP2007552375 A JP 2007552375A JP 2008528512 A5 JP2008528512 A5 JP 2008528512A5
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- JP
- Japan
- Prior art keywords
- kda
- molecular weight
- isolated
- polypeptide
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229920001184 polypeptide Polymers 0.000 claims 72
- 108090000765 processed proteins & peptides Proteins 0.000 claims 72
- 102000004196 processed proteins & peptides Human genes 0.000 claims 72
- 239000000203 mixture Substances 0.000 claims 37
- OEUUFNIKLCFNLN-LLVKDONJSA-N chembl432481 Chemical compound OC(=O)[C@@]1(C)CSC(C=2C(=CC(O)=CC=2)O)=N1 OEUUFNIKLCFNLN-LLVKDONJSA-N 0.000 claims 32
- 241000607447 Yersinia enterocolitica Species 0.000 claims 28
- 239000008194 pharmaceutical composition Substances 0.000 claims 28
- 229920002401 polyacrylamide Polymers 0.000 claims 24
- 238000001962 electrophoresis Methods 0.000 claims 23
- 208000015181 infectious disease Diseases 0.000 claims 15
- 229940098232 yersinia enterocolitica Drugs 0.000 claims 15
- SNRUBQQJIBEYMU-UHFFFAOYSA-N Dodecane Natural products CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 claims 14
- 229910052708 sodium Inorganic materials 0.000 claims 14
- 239000011734 sodium Substances 0.000 claims 14
- 241000699670 Mus sp. Species 0.000 claims 11
- 241000607479 Yersinia pestis Species 0.000 claims 11
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical group [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims 10
- 241000607734 Yersinia <bacteria> Species 0.000 claims 9
- 241000699666 Mus <mouse, genus> Species 0.000 claims 8
- 241001117074 Yersinia pestis KIM10+ Species 0.000 claims 8
- 239000000797 iron chelating agent Substances 0.000 claims 6
- 229940075525 iron chelating agent Drugs 0.000 claims 6
- 241001148129 Yersinia ruckeri Species 0.000 claims 3
- 208000024891 symptom Diseases 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- FSYKKLYZXJSNPZ-UHFFFAOYSA-N sarcosine Chemical compound C[NH2+]CC([O-])=O FSYKKLYZXJSNPZ-UHFFFAOYSA-N 0.000 claims 2
- YPFNIPKMNMDDDB-UHFFFAOYSA-K 2-[2-[bis(carboxylatomethyl)amino]ethyl-(2-hydroxyethyl)amino]acetate;iron(3+) Chemical compound [Fe+3].OCCN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O YPFNIPKMNMDDDB-UHFFFAOYSA-K 0.000 claims 1
- 241000251468 Actinopterygii Species 0.000 claims 1
- 206010012735 Diarrhoea Diseases 0.000 claims 1
- 208000004232 Enteritis Diseases 0.000 claims 1
- 206010035148 Plague Diseases 0.000 claims 1
- 108010077895 Sarcosine Proteins 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229940043230 sarcosine Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64610605P | 2005-01-21 | 2005-01-21 | |
| PCT/US2006/002474 WO2006079076A2 (en) | 2005-01-21 | 2006-01-20 | Yersinia spp. polypeptides and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012209231A Division JP6178059B2 (ja) | 2005-01-21 | 2012-09-24 | エルシニアｓｐｐ．ポリペプチド及び使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008528512A JP2008528512A (ja) | 2008-07-31 |
| JP2008528512A5 true JP2008528512A5 (enExample) | 2009-03-12 |
Family
ID=36649588
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007552375A Withdrawn JP2008528512A (ja) | 2005-01-21 | 2006-01-20 | エルシニアｓｐｐ．ポリペプチド及び使用方法 |
| JP2012209231A Active JP6178059B2 (ja) | 2005-01-21 | 2012-09-24 | エルシニアｓｐｐ．ポリペプチド及び使用方法 |
| JP2015139060A Active JP6224655B2 (ja) | 2005-01-21 | 2015-07-10 | エルシニアｓｐｐ．ポリペプチド及び使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012209231A Active JP6178059B2 (ja) | 2005-01-21 | 2012-09-24 | エルシニアｓｐｐ．ポリペプチド及び使用方法 |
| JP2015139060A Active JP6224655B2 (ja) | 2005-01-21 | 2015-07-10 | エルシニアｓｐｐ．ポリペプチド及び使用方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (8) | US8563004B2 (enExample) |
| EP (3) | EP2431382A1 (enExample) |
| JP (3) | JP2008528512A (enExample) |
| CN (1) | CN101142230A (enExample) |
| AU (1) | AU2006206234B2 (enExample) |
| BR (1) | BRPI0606506A2 (enExample) |
| CA (1) | CA2595163A1 (enExample) |
| DK (1) | DK1848732T3 (enExample) |
| ES (1) | ES2588010T3 (enExample) |
| MX (1) | MX2007008723A (enExample) |
| NZ (1) | NZ556651A (enExample) |
| WO (1) | WO2006079076A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5830479A (en) * | 1994-02-09 | 1998-11-03 | Willmar Poultry Company, Inc. | Active immunization using a siderophore receptor protein |
| ES2279511T3 (es) * | 1994-02-09 | 2007-08-16 | Epitopix Llc | Inmunizacion activa utilizando una proteina receptor de sideroforo. |
| BR0206293B1 (pt) * | 2001-01-03 | 2015-01-20 | Epitopix Llc | composições compreendendo polipeptídeos receptores de sideróforos e porinas de micróbio gram-negativo, bem como métodos de isolar polipeptídeos de membrana externa |
| BRPI0414267A (pt) | 2003-09-19 | 2006-11-21 | Epitopix Llc | polipeptìdeos de campilobacter e métodos de uso |
| MX2007008723A (es) | 2005-01-21 | 2007-09-12 | Epitopix Llc | Polipeptidos de yersinia spp y metodos de uso. |
| CN107325165A (zh) * | 2011-05-31 | 2017-11-07 | 和黄生物膜医疗解决方案有限公司 | 细胞聚集体的分散和脱离 |
| US9631221B1 (en) | 2011-09-02 | 2017-04-25 | Becton, Dickinson And Company | Identification of microorganisms using MALDI-TOF-MS on-plate extraction |
| KR101948400B1 (ko) * | 2011-12-29 | 2019-02-14 | 타오 헬스 라이프 파마 가부시키가이샤 | 아밀로스페로이드가 결합하여 성숙 신경 세포사를 유발하는 표적 분자, 아밀로스페로이드가 유도하는 신경 세포사를 억제하는 방법 및 물질, 및 그들의 이용 |
| JP6141205B2 (ja) * | 2012-02-13 | 2017-06-07 | 国立大学法人京都工芸繊維大学 | 窒化ケイ素（Ｓｉ３Ｎ４）親和性ペプチド、及びその利用 |
| US8753643B1 (en) | 2012-04-11 | 2014-06-17 | Life-Science Innovations, Llc | Spray dried compositions and methods of use |
| US9017953B2 (en) * | 2012-05-18 | 2015-04-28 | Washington University | Biomarker and therapeutic for urinary tract infection |
| RU2549712C1 (ru) * | 2013-11-26 | 2015-04-27 | Федеральное казенное учреждение здравоохранения "Ростовский-на-Дону ордена Трудового Красного Знамени научно-исследовательский противочумный институт" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека | CПОСОБ ВЫДЕЛЕНИЯ ИНГИБИТОРА СЕКРЕЦИИ СИДЕРОФОРОВ, СИНТЕЗИРУЕМОГО pgm- ШТАММАМИ Y. pestis И ВЫДЕЛЕННЫЙ ИНГИБИТОР |
| FR3024903A1 (fr) * | 2014-08-14 | 2016-02-19 | Biomerieux Sa | Procede de quantification d'au moins un groupe de microorganismes par spectrometrie de masse |
| AU2015329723A1 (en) * | 2014-10-10 | 2017-04-27 | Rare Element Resources, Ltd. | Processing for the extraction of rare earth elements |
| KR102435324B1 (ko) | 2015-01-20 | 2022-08-23 | 아이쥐엠 바이오사이언스 인코포레이티드 | 종양 괴사 인자(ｔｎｆ) 수퍼패밀리 수용체 결합 분자 및 그의 용도 |
| WO2017083367A1 (en) | 2015-11-09 | 2017-05-18 | Epitopix, Llc | Polypeptides of fusobacterium and methods of use |
| US10166280B2 (en) | 2016-06-08 | 2019-01-01 | Epitopix, Llc | Polypeptides and immunizing compositions containing Bacillus polypeptides and methods of use |
| MX2019009409A (es) | 2017-02-10 | 2019-09-27 | Epitopix Llc | Proteinas y composiciones de inmunizacion que contienen proteinas de pasteurella y metodos de uso. |
| WO2021076865A1 (en) * | 2019-10-18 | 2021-04-22 | University Of Utah Research Foundation | Polymeric drug delivery conjugates and methods of making and using thereof |
| CN113679829B (zh) * | 2020-05-18 | 2024-01-02 | 北京繁易纳维科技有限公司 | 一种预防癌症术后复发的肿瘤疫苗及其制备方法和应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5420253A (en) | 1993-09-09 | 1995-05-30 | Willmar Poultry Company, Inc. | Method for purifying egg yolk immunoglobulins |
| ES2279511T3 (es) | 1994-02-09 | 2007-08-16 | Epitopix Llc | Inmunizacion activa utilizando una proteina receptor de sideroforo. |
| US5830479A (en) | 1994-02-09 | 1998-11-03 | Willmar Poultry Company, Inc. | Active immunization using a siderophore receptor protein |
| WO1995025742A1 (en) | 1994-03-22 | 1995-09-28 | Pfizer Inc. | Pasteurellaceae antigens and related vaccines |
| US5538733A (en) | 1994-07-07 | 1996-07-23 | Willmar Poultry Company, Inc. | Method of priming an immune response in a one-day old animal |
| AU5597998A (en) * | 1996-12-04 | 1998-06-29 | Heska Corporation | Recombinant plague vaccine |
| US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
| US6610836B1 (en) | 1999-01-29 | 2003-08-26 | Genome Therapeutics Corporation | Nucleic acid amino acid sequences relating to Klebsiella pneumoniae for diagnostics and therapeutics |
| US6682754B2 (en) | 1999-11-24 | 2004-01-27 | Willmar Poultry Company, Inc. | Ovo delivery of an immunogen containing implant |
| US20020061569A1 (en) | 2000-03-21 | 2002-05-23 | Robert Haselbeck | Identification of essential genes in prokaryotes |
| BR0206293B1 (pt) | 2001-01-03 | 2015-01-20 | Epitopix Llc | composições compreendendo polipeptídeos receptores de sideróforos e porinas de micróbio gram-negativo, bem como métodos de isolar polipeptídeos de membrana externa |
| AT410798B (de) | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
| GB0127657D0 (en) | 2001-11-19 | 2002-01-09 | Microscience Ltd | Virulence genes and proteins and their use |
| CA2489030A1 (en) | 2002-08-02 | 2004-02-19 | Glaxosmithkline Biologicals S.A. | Vaccine composition comprising transferrin binding protein and hsf from gram negative bacteria |
| BRPI0414267A (pt) | 2003-09-19 | 2006-11-21 | Epitopix Llc | polipeptìdeos de campilobacter e métodos de uso |
| CN101014618B (zh) | 2004-07-23 | 2013-01-02 | 诺华疫苗和诊断有限公司 | 抗原的寡聚装配多肽 |
| NZ553315A (en) | 2004-08-25 | 2009-12-24 | Epitopix Llc | Fusobacterium polypeptides and methods of use |
| MX2007008723A (es) | 2005-01-21 | 2007-09-12 | Epitopix Llc | Polipeptidos de yersinia spp y metodos de uso. |
| EP2298795A1 (en) | 2005-02-18 | 2011-03-23 | Novartis Vaccines and Diagnostics, Inc. | Immunogens from uropathogenic escherichia coli |
| WO2006113907A2 (en) * | 2005-04-20 | 2006-10-26 | The General Hospital Corporation | Escherichia coli o157:h7 proteins and uses thereof |
-
2006
- 2006-01-20 MX MX2007008723A patent/MX2007008723A/es active IP Right Grant
- 2006-01-20 EP EP11007570A patent/EP2431382A1/en not_active Withdrawn
- 2006-01-20 CA CA002595163A patent/CA2595163A1/en not_active Abandoned
- 2006-01-20 JP JP2007552375A patent/JP2008528512A/ja not_active Withdrawn
- 2006-01-20 EP EP06719369.8A patent/EP1848732B1/en active Active
- 2006-01-20 US US11/336,706 patent/US8563004B2/en active Active
- 2006-01-20 NZ NZ556651A patent/NZ556651A/en not_active IP Right Cessation
- 2006-01-20 BR BRPI0606506-6A patent/BRPI0606506A2/pt not_active Application Discontinuation
- 2006-01-20 ES ES06719369.8T patent/ES2588010T3/es active Active
- 2006-01-20 DK DK06719369.8T patent/DK1848732T3/en active
- 2006-01-20 CN CNA2006800028566A patent/CN101142230A/zh active Pending
- 2006-01-20 WO PCT/US2006/002474 patent/WO2006079076A2/en not_active Ceased
- 2006-01-20 AU AU2006206234A patent/AU2006206234B2/en not_active Ceased
- 2006-01-20 EP EP11075020A patent/EP2361926A3/en not_active Withdrawn
-
2011
- 2011-01-31 US US13/018,292 patent/US20110206674A1/en not_active Abandoned
-
2012
- 2012-09-24 JP JP2012209231A patent/JP6178059B2/ja active Active
-
2013
- 2013-10-08 US US14/048,649 patent/US9085613B2/en active Active
- 2013-10-08 US US14/048,640 patent/US9085612B2/en active Active
- 2013-10-08 US US14/048,643 patent/US9109018B2/en active Active
-
2015
- 2015-07-07 US US14/793,494 patent/US9221899B2/en active Active
- 2015-07-10 JP JP2015139060A patent/JP6224655B2/ja active Active
- 2015-11-05 US US14/933,899 patent/US9352029B2/en active Active
-
2016
- 2016-04-28 US US15/140,767 patent/US9801932B2/en active Active
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