JP2021500922A5 - - Google Patents

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Publication number
JP2021500922A5
JP2021500922A5 JP2020542710A JP2020542710A JP2021500922A5 JP 2021500922 A5 JP2021500922 A5 JP 2021500922A5 JP 2020542710 A JP2020542710 A JP 2020542710A JP 2020542710 A JP2020542710 A JP 2020542710A JP 2021500922 A5 JP2021500922 A5 JP 2021500922A5
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JP
Japan
Prior art keywords
promoter
cfh
item
aav vector
aav
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2020542710A
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English (en)
Japanese (ja)
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JP2021500922A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/056709 external-priority patent/WO2019079718A1/en
Publication of JP2021500922A publication Critical patent/JP2021500922A/ja
Publication of JP2021500922A5 publication Critical patent/JP2021500922A5/ja
Withdrawn legal-status Critical Current

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JP2020542710A 2017-10-20 2018-10-19 加齢黄斑変性を処置するための組成物および方法 Withdrawn JP2021500922A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762574814P 2017-10-20 2017-10-20
US62/574,814 2017-10-20
PCT/US2018/056709 WO2019079718A1 (en) 2017-10-20 2018-10-19 COMPOSITIONS AND METHODS FOR TREATING AGE-RELATED MACULAR DEGENERATION

Publications (2)

Publication Number Publication Date
JP2021500922A JP2021500922A (ja) 2021-01-14
JP2021500922A5 true JP2021500922A5 (enExample) 2021-11-25

Family

ID=66174265

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020542710A Withdrawn JP2021500922A (ja) 2017-10-20 2018-10-19 加齢黄斑変性を処置するための組成物および方法

Country Status (7)

Country Link
US (1) US20210188927A1 (enExample)
EP (1) EP3697920A4 (enExample)
JP (1) JP2021500922A (enExample)
CN (1) CN111788311A (enExample)
AU (1) AU2018351491A1 (enExample)
CA (1) CA3079553A1 (enExample)
WO (1) WO2019079718A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210338838A1 (en) * 2018-07-20 2021-11-04 University Of Utah Research Foundation Gene therapy for macular degeneration
EP3870711A1 (en) * 2018-10-23 2021-09-01 Gemini Therapeutics Inc. Compositions and methods for treating age-related macular degeneration and other diseases
GB201821089D0 (en) 2018-12-21 2019-02-06 Gyroscope Therapeutics Ltd Codon-optimised complement factor I
IL292379A (en) * 2019-10-22 2022-06-01 Applied Genetic Tech Corporation Adeno-associated virus (aav)vectors for the treatment of age-related macular degeneration and other ocular diseases and disorders
WO2021081395A1 (en) * 2019-10-23 2021-04-29 Gemini Therapeutics Inc. Methods for treating patients having cfh mutations with recombinant cfh proteins
GB202003618D0 (en) 2020-03-12 2020-04-29 Univ Bristol Gene Therapy
IL299048A (en) 2020-06-14 2023-02-01 Vertex Pharma Variants of complement factor - 1 fusion structures and preparations containing them and their uses
WO2022079453A1 (en) * 2020-10-16 2022-04-21 Gyroscope Therapeutics Limited Nucleic acid encoding an anti-vegf entity and a negative complement regulator and uses thereof for the treatment of age-related macular degeneration
US20240024416A1 (en) * 2020-10-30 2024-01-25 Gemini Therapeutics Sub, Inc. Methods for treating inflammatory ocular diseases with complement factor h
CN115786308B (zh) * 2022-11-24 2024-05-31 江苏海洋大学 一种提高右旋糖酐酶热稳定性的方法及突变体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005333845A (ja) * 2004-05-25 2005-12-08 Tokyoto Igaku Kenkyu Kiko ミトコンドリア局在型DsRed2及びECFP発現ベクター
US8088579B2 (en) * 2005-02-14 2012-01-03 University Of Iowa Research Foundation Complement factor H for diagnosis of age-related macular degeneration
EP3359663A4 (en) * 2015-09-24 2019-08-14 The Trustees of The University of Pennsylvania COMPOSITION AND METHOD FOR THE TREATMENT OF A COMPLEMENT-MEDIATED DISEASE
GB201519086D0 (en) * 2015-10-28 2015-12-09 Syncona Partners Llp Gene Therapy

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