JP2021500922A - 加齢黄斑変性を処置するための組成物および方法 - Google Patents
加齢黄斑変性を処置するための組成物および方法 Download PDFInfo
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
- A61K48/0058—Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
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- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14145—Special targeting system for viral vectors
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- C12N2800/00—Nucleic acids vectors
- C12N2800/22—Vectors comprising a coding region that has been codon optimised for expression in a respective host
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/60—Vectors containing traps for, e.g. exons, promoters
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/007—Vectors comprising a special translation-regulating system cell or tissue specific
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762574814P | 2017-10-20 | 2017-10-20 | |
| US62/574,814 | 2017-10-20 | ||
| PCT/US2018/056709 WO2019079718A1 (en) | 2017-10-20 | 2018-10-19 | COMPOSITIONS AND METHODS FOR TREATING AGE-RELATED MACULAR DEGENERATION |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021500922A true JP2021500922A (ja) | 2021-01-14 |
| JP2021500922A5 JP2021500922A5 (enExample) | 2021-11-25 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020542710A Withdrawn JP2021500922A (ja) | 2017-10-20 | 2018-10-19 | 加齢黄斑変性を処置するための組成物および方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20210188927A1 (enExample) |
| EP (1) | EP3697920A4 (enExample) |
| JP (1) | JP2021500922A (enExample) |
| CN (1) | CN111788311A (enExample) |
| AU (1) | AU2018351491A1 (enExample) |
| CA (1) | CA3079553A1 (enExample) |
| WO (1) | WO2019079718A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020019002A1 (en) * | 2018-07-20 | 2020-01-23 | University Of Utah Research Foundation | Gene therapy for macular degeneration |
| CA3117551A1 (en) * | 2018-10-23 | 2020-04-30 | Gemini Therapeutics Inc. | Compositions and methods for treating age-related macular degeneration and other diseases |
| GB201821089D0 (en) | 2018-12-21 | 2019-02-06 | Gyroscope Therapeutics Ltd | Codon-optimised complement factor I |
| JP2022553309A (ja) * | 2019-10-22 | 2022-12-22 | アプライド ジェネティック テクノロジーズ コーポレイション | 加齢黄斑変性ならびに他の眼疾患および障害の治療のためのアデノ随伴ウイルス（ａａｖ）ベクター |
| MX2022004939A (es) * | 2019-10-23 | 2022-08-10 | Gemini Therapeutics Sub Inc | Metodos para tratar pacientes que tienen mutaciones de cfh con proteinas de cfh recombinantes. |
| GB202003618D0 (en) | 2020-03-12 | 2020-04-29 | Univ Bristol | Gene Therapy |
| WO2021257480A2 (en) | 2020-06-14 | 2021-12-23 | Catalyst Biosciences, Inc. | Complement factor i-related compositions and methods |
| KR20230088630A (ko) * | 2020-10-16 | 2023-06-20 | 자이로스코프 테라퓨틱스 리미티드 | 항-vegf 엔티티 및 음성 보체 조절인자를 코딩하는 핵산 및 연령-관련 황반 변성의 치료를 위한 그의 용도 |
| US20240024416A1 (en) * | 2020-10-30 | 2024-01-25 | Gemini Therapeutics Sub, Inc. | Methods for treating inflammatory ocular diseases with complement factor h |
| CN115786308B (zh) * | 2022-11-24 | 2024-05-31 | 江苏海洋大学 | 一种提高右旋糖酐酶热稳定性的方法及突变体 |
| CN121490062B (zh) * | 2026-01-12 | 2026-05-15 | 上饶爱尔眼科医院有限公司 | 含地塞米松的组合物及其在制备治疗视网膜病变的药物中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005333845A (ja) * | 2004-05-25 | 2005-12-08 | Tokyoto Igaku Kenkyu Kiko | ミトコンドリア局在型ＤｓＲｅｄ２及びＥＣＦＰ発現ベクター |
| US7745389B2 (en) * | 2005-02-14 | 2010-06-29 | University Of Iowa Research Foundation | Methods for treatment of age-related macular degeneration |
| EP3359663A4 (en) * | 2015-09-24 | 2019-08-14 | The Trustees of The University of Pennsylvania | COMPOSITION AND METHOD FOR THE TREATMENT OF A COMPLEMENT-MEDIATED DISEASE |
| GB201519086D0 (en) * | 2015-10-28 | 2015-12-09 | Syncona Partners Llp | Gene Therapy |
-
2018
- 2018-10-19 CN CN201880078342.1A patent/CN111788311A/zh active Pending
- 2018-10-19 CA CA3079553A patent/CA3079553A1/en not_active Abandoned
- 2018-10-19 WO PCT/US2018/056709 patent/WO2019079718A1/en not_active Ceased
- 2018-10-19 JP JP2020542710A patent/JP2021500922A/ja not_active Withdrawn
- 2018-10-19 EP EP18869436.8A patent/EP3697920A4/en not_active Withdrawn
- 2018-10-19 AU AU2018351491A patent/AU2018351491A1/en not_active Abandoned
- 2018-10-19 US US16/757,268 patent/US20210188927A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018351491A1 (en) | 2020-05-07 |
| WO2019079718A1 (en) | 2019-04-25 |
| US20210188927A1 (en) | 2021-06-24 |
| EP3697920A4 (en) | 2022-03-02 |
| CA3079553A1 (en) | 2019-04-25 |
| EP3697920A1 (en) | 2020-08-26 |
| CN111788311A (zh) | 2020-10-16 |
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