JP2021169519A5 - - Google Patents
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- JP2021169519A5 JP2021169519A5 JP2021119885A JP2021119885A JP2021169519A5 JP 2021169519 A5 JP2021169519 A5 JP 2021169519A5 JP 2021119885 A JP2021119885 A JP 2021119885A JP 2021119885 A JP2021119885 A JP 2021119885A JP 2021169519 A5 JP2021169519 A5 JP 2021169519A5
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- Prior art keywords
- complex
- deficiency
- side effects
- butyl
- acyl
- Prior art date
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201470190 | 2014-04-08 | ||
| DKPA201470190 | 2014-04-08 | ||
| JP2020018467A JP7229189B2 (ja) | 2014-04-08 | 2020-02-06 | 新規な細胞透過性サクシネート化合物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020018467A Division JP7229189B2 (ja) | 2014-04-08 | 2020-02-06 | 新規な細胞透過性サクシネート化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021169519A JP2021169519A (ja) | 2021-10-28 |
| JP2021169519A5 true JP2021169519A5 (https=) | 2021-12-23 |
Family
ID=58804197
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016561677A Active JP7082861B6 (ja) | 2014-04-08 | 2015-04-08 | 新規な細胞透過性サクシネート化合物 |
| JP2020018467A Active JP7229189B2 (ja) | 2014-04-08 | 2020-02-06 | 新規な細胞透過性サクシネート化合物 |
| JP2021119885A Pending JP2021169519A (ja) | 2014-04-08 | 2021-07-20 | 新規な細胞透過性サクシネート化合物 |
| JP2021119813A Pending JP2021169518A (ja) | 2014-04-08 | 2021-07-20 | 新規な細胞透過性サクシネート化合物 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016561677A Active JP7082861B6 (ja) | 2014-04-08 | 2015-04-08 | 新規な細胞透過性サクシネート化合物 |
| JP2020018467A Active JP7229189B2 (ja) | 2014-04-08 | 2020-02-06 | 新規な細胞透過性サクシネート化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021119813A Pending JP2021169518A (ja) | 2014-04-08 | 2021-07-20 | 新規な細胞透過性サクシネート化合物 |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US11147789B2 (https=) |
| EP (2) | EP3129016B1 (https=) |
| JP (4) | JP7082861B6 (https=) |
| KR (1) | KR102322543B1 (https=) |
| CN (1) | CN106458957B (https=) |
| AU (2) | AU2015243346C9 (https=) |
| CA (1) | CA2944565C (https=) |
| CY (1) | CY1120650T1 (https=) |
| DK (1) | DK3129016T3 (https=) |
| EA (1) | EA035678B1 (https=) |
| ES (2) | ES2683860T3 (https=) |
| HR (1) | HRP20181126T1 (https=) |
| IL (1) | IL247904B (https=) |
| LT (2) | LT3391941T (https=) |
| MA (2) | MA44092B1 (https=) |
| MX (1) | MX378072B (https=) |
| PL (1) | PL3129016T3 (https=) |
| PT (2) | PT3129016T (https=) |
| RS (1) | RS57624B1 (https=) |
| SG (1) | SG11201607907PA (https=) |
| SI (1) | SI3129016T1 (https=) |
| SM (1) | SMT201800429T1 (https=) |
| TR (1) | TR201810411T4 (https=) |
| WO (1) | WO2015155231A1 (https=) |
| ZA (1) | ZA201606608B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA39856A (fr) * | 2014-04-08 | 2017-02-15 | Neurovive Pharmaceutical Ab | Promédicaments d'acide succinique pour augmenter la production d'atp |
| WO2015155238A1 (en) | 2014-04-08 | 2015-10-15 | Neurovive Pharmaceutical Ab | Succinate prodrugs for use in the treatment of lactic acidosis or drug-induced side-effects due to complex i-related impairment of mitochondrial oxidative phosphorylation |
| TR201810411T4 (tr) * | 2014-04-08 | 2018-08-27 | Neurovive Pharmaceutical Ab | Özgün hücre geçirgen süksinat bileşikleri. |
| WO2017060418A1 (en) * | 2015-10-07 | 2017-04-13 | Neurovive Pharmaceutical Ab | Protected carboxylic acid-based metabolites for the treatment of mitochondria-related diseases |
| WO2017060420A1 (en) * | 2015-10-07 | 2017-04-13 | Neurovive Pharmaceutical Ab | Protected fumaric acid-based metabolites for the treatment of autoimmune diseases |
| WO2017060422A1 (en) * | 2015-10-07 | 2017-04-13 | Neurovive Pharmaceutical Ab | Protected carboxylic acid-based metabolites for the treatment of mitochondrial disorders |
| WO2017096270A1 (en) | 2015-12-03 | 2017-06-08 | The Regents Of The University Of California | Methods for treating mitochondrial diseases |
| CA3113071A1 (en) * | 2018-10-11 | 2020-04-16 | Imbria Pharmaceuticals, Inc. | Tca cycle intermediates and methods of use thereof |
| CN112888419A (zh) * | 2018-10-11 | 2021-06-01 | 安布里亚制药公司 | 用于治疗和预防Leber遗传性视神经病变的组合物和方法 |
| CN109675037B (zh) * | 2019-01-25 | 2021-09-14 | 南方医科大学 | Atp及其受体在制备治疗自闭症药物中的应用 |
| IL288990B2 (en) * | 2019-06-19 | 2025-09-01 | Abliva Ab | Succinate drug meters, preparations containing the succinate drug meters and its uses |
Family Cites Families (24)
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|---|---|---|---|---|
| GB756422A (en) * | 1950-09-14 | 1956-09-05 | Saint Gobain | Esters of urethanes of glycols and the manufacture thereof |
| NL6806584A (https=) * | 1965-09-20 | 1968-11-12 | ||
| FR2265355B1 (https=) * | 1974-03-28 | 1977-11-04 | Blum Jean | |
| US5112953A (en) * | 1989-12-29 | 1992-05-12 | Neorx Corporation | Radiolabeled proteins for diagnostic or therapeutic use |
| DE4101158C2 (de) * | 1991-01-14 | 1994-06-23 | Dainippon Ink & Chemicals | Wärmehärtbare Reaktionsharzgemische, Verwendung der erfindungsgemäßen Reaktionsharze zur Herstellung von Formkörpern und Beschichtungen |
| CA2107581A1 (en) | 1992-02-07 | 1993-08-08 | Kiyoshi Sugiyama | Side-effect alleviant |
| JPH07331262A (ja) * | 1994-05-31 | 1995-12-19 | Tonen Corp | パティキュレート低減用添加剤及び該添加剤を用いたディーゼルエンジン用燃料組成物 |
| GB9612331D0 (en) * | 1996-06-13 | 1996-08-14 | Leo Pharm Prod Ltd | Chemical compounds |
| CN1222139A (zh) * | 1996-06-13 | 1999-07-07 | 里奥药物制品有限公司 | 多元醇琥珀酸酯及其药物制剂 |
| CA2341640A1 (en) | 1998-07-02 | 2000-01-13 | Chaitan Khosla | Methods for making polyketides using altered pks |
| AUPR059400A0 (en) * | 2000-10-06 | 2000-11-02 | Bar-Ilan University | Formaldehyde-releasing prodrugs |
| EP1401850A1 (en) * | 2001-06-20 | 2004-03-31 | Nuevolution A/S | Nucleoside derivatives for library preparation |
| US7468383B2 (en) | 2005-02-11 | 2008-12-23 | Cephalon, Inc. | Proteasome inhibitors and methods of using the same |
| KR100791844B1 (ko) | 2006-06-30 | 2008-01-07 | 주식회사유한양행 | 메트포르민 또는 그의 염을 함유하는 서방성 제제 및 그의제조방법 |
| KR101069502B1 (ko) | 2006-10-31 | 2011-09-30 | (주)아모레퍼시픽 | 비만 및 당뇨병 개선용 경구용 조성물 |
| US20120308646A1 (en) * | 2007-01-18 | 2012-12-06 | Hesheng Zhang | Tetracyclic anthraquinones possessing anti-cancer properties |
| EP2139320A4 (en) | 2007-03-26 | 2010-09-08 | Salutria Pharmaceuticals Llc | METHODS AND COMPOSITIONS OF PROBUCOL DERIVATIVES FOR THE TREATMENT OF DIABETES |
| US8410139B2 (en) * | 2009-10-07 | 2013-04-02 | Bristol-Myers Squibb Company | Prodrugs of a piperidinyl derivative as modulators of chemokine receptor activity |
| IT1406068B1 (it) | 2010-07-22 | 2014-02-06 | Medestea Int Spa | Polidesossiribonucleotidi (pdrn) per l'impiego nel trattamento di condizioni di acidosi e composizioni a base di polidesossiribonucleotidi per il suddetto impiego |
| JP2014024772A (ja) | 2012-07-25 | 2014-02-06 | Univ Of Tokyo | ミトコンドリアのａｔｐ産生能昂進剤 |
| WO2014053857A1 (en) | 2012-10-05 | 2014-04-10 | Mitopharm Ltd | Protected succinates for enhancing mitochondrial atp-production |
| TR201810411T4 (tr) * | 2014-04-08 | 2018-08-27 | Neurovive Pharmaceutical Ab | Özgün hücre geçirgen süksinat bileşikleri. |
| WO2015155238A1 (en) | 2014-04-08 | 2015-10-15 | Neurovive Pharmaceutical Ab | Succinate prodrugs for use in the treatment of lactic acidosis or drug-induced side-effects due to complex i-related impairment of mitochondrial oxidative phosphorylation |
| MA39856A (fr) | 2014-04-08 | 2017-02-15 | Neurovive Pharmaceutical Ab | Promédicaments d'acide succinique pour augmenter la production d'atp |
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