CY1120650T1 - Νεες κυτταρο-διαπερατες ενωσεις ηλεκτρικου - Google Patents
Νεες κυτταρο-διαπερατες ενωσεις ηλεκτρικουInfo
- Publication number
- CY1120650T1 CY1120650T1 CY181100892T CY181100892T CY1120650T1 CY 1120650 T1 CY1120650 T1 CY 1120650T1 CY 181100892 T CY181100892 T CY 181100892T CY 181100892 T CY181100892 T CY 181100892T CY 1120650 T1 CY1120650 T1 CY 1120650T1
- Authority
- CY
- Cyprus
- Prior art keywords
- permeable
- electrical
- cell
- new cell
- permeable electrical
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
- C07C327/34—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups with amino groups bound to the same hydrocarbon radicals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/28—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/30—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/18—Eight-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
Η παρούσα εφεύρεση παρέχει νέες κύτταρο- διαπερατές ηλεκτρικού και κύτταρο-διαπερατά πρόδρομα ηλεκτρικού που αποσκοπούν στην αύξηση της παραγωγής ΑΤΡ στα μιτοχόνδρια. Το κύριο μέρος του ΑΤΡ που παράγεται και χρησιμοποιείται στο ευκαρυωτικό κύτταρο προέρχεται από τη μιτοχονδριακή οξειδωτική φωσφορυλίωση, μια διαδικασία στην οποία τα ηλεκτρόνια υψηλής ενέργειας παρέχονται από τον κύκλο του Kreb. Δεν είναι όλα τα ενδιάμεσα προϊόντα στον κύκλου του Kreb εύκολα διαπερατά από την κυτταρική μεμβράνη, μία από τις οποίες είναι ηλεκτρική. Η πρόβλεψη των νέων κύτταρο-διαπερατών ηλεκτρικού αναμένεται να επιτρέψει τη διέλευση από την κυτταρική μεμβράνη και έτσι τα κύτταρο-διαπερατά ηλεκτρικού μπορούν να χρησιμοποιηθούν για την ενίσχυση της παραγωγής μιτοχονδριακού ΑΤΡ.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA201470190 | 2014-04-08 | ||
PCT/EP2015/057606 WO2015155231A1 (en) | 2014-04-08 | 2015-04-08 | Novel cell-permeable succinate compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1120650T1 true CY1120650T1 (el) | 2019-12-11 |
Family
ID=58804197
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY181100892T CY1120650T1 (el) | 2014-04-08 | 2018-08-27 | Νεες κυτταρο-διαπερατες ενωσεις ηλεκτρικου |
Country Status (25)
Country | Link |
---|---|
US (2) | US11147789B2 (el) |
EP (2) | EP3391941B1 (el) |
JP (4) | JP7082861B6 (el) |
KR (1) | KR102322543B1 (el) |
CN (1) | CN106458957B (el) |
AU (2) | AU2015243346C9 (el) |
CA (1) | CA2944565C (el) |
CY (1) | CY1120650T1 (el) |
DK (1) | DK3129016T3 (el) |
EA (1) | EA035678B1 (el) |
ES (2) | ES2953522T3 (el) |
HK (1) | HK1255109A1 (el) |
HR (1) | HRP20181126T1 (el) |
IL (1) | IL247904B (el) |
LT (2) | LT3391941T (el) |
MA (2) | MA39855B1 (el) |
MX (1) | MX2016012691A (el) |
PL (1) | PL3129016T3 (el) |
PT (2) | PT3391941T (el) |
RS (1) | RS57624B1 (el) |
SG (1) | SG11201607907PA (el) |
SI (1) | SI3129016T1 (el) |
TR (1) | TR201810411T4 (el) |
WO (1) | WO2015155231A1 (el) |
ZA (1) | ZA201606608B (el) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015155230A1 (en) * | 2014-04-08 | 2015-10-15 | Neurovive Pharmaceutical Ab | Prodrugs of succinic acid for increasing atp production |
EA035678B1 (ru) * | 2014-04-08 | 2020-07-24 | Ньюроувив Фармасьютикал Аб | Новые клеточно-проницаемые сукцинатные соединения |
MA39857A (fr) | 2014-04-08 | 2017-02-15 | Neurovive Pharmaceutical Ab | Promédicaments à base de succinate destinés à être utilisés dans le traitement de l'acidose lactique ou d'effets secondaires induits par un médicament dus à une déficience liée au complexe i de la phosphorylation oxydative mitochondriale |
WO2017060418A1 (en) * | 2015-10-07 | 2017-04-13 | Neurovive Pharmaceutical Ab | Protected carboxylic acid-based metabolites for the treatment of mitochondria-related diseases |
WO2017060422A1 (en) * | 2015-10-07 | 2017-04-13 | Neurovive Pharmaceutical Ab | Protected carboxylic acid-based metabolites for the treatment of mitochondrial disorders |
WO2017060400A1 (en) * | 2015-10-07 | 2017-04-13 | Neurovive Pharmaceutical Ab | Protected carboxylic acid-based metabolites for the treatment of disesases related to mitochondrial dysfunctions |
WO2017096270A1 (en) | 2015-12-03 | 2017-06-08 | The Regents Of The University Of California | Methods for treating mitochondrial diseases |
JP2022504585A (ja) * | 2018-10-11 | 2022-01-13 | インブリア ファーマシューティカルズ, インコーポレイテッド | レーベル遺伝性視神経症を処置および防止するための組成物および方法 |
KR20210076040A (ko) * | 2018-10-11 | 2021-06-23 | 임브리아 파마슈티칼스, 인크. | Tca 회로 중간체 및 그의 사용 방법 |
CN109675037B (zh) * | 2019-01-25 | 2021-09-14 | 南方医科大学 | Atp及其受体在制备治疗自闭症药物中的应用 |
US11565998B2 (en) * | 2019-06-19 | 2023-01-31 | Abliva Ab | Succinate prodrug, compositions containing the succinate prodrug and uses thereof |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB756422A (en) * | 1950-09-14 | 1956-09-05 | Saint Gobain | Esters of urethanes of glycols and the manufacture thereof |
NL6806584A (el) * | 1965-09-20 | 1968-11-12 | ||
FR2265355B1 (el) | 1974-03-28 | 1977-11-04 | Blum Jean | |
US5112953A (en) * | 1989-12-29 | 1992-05-12 | Neorx Corporation | Radiolabeled proteins for diagnostic or therapeutic use |
DE4101158C2 (de) * | 1991-01-14 | 1994-06-23 | Dainippon Ink & Chemicals | Wärmehärtbare Reaktionsharzgemische, Verwendung der erfindungsgemäßen Reaktionsharze zur Herstellung von Formkörpern und Beschichtungen |
WO1993015729A1 (fr) | 1992-02-07 | 1993-08-19 | Tsumura & Co. | Agent d'attenuation des effets secondaires |
JPH07331262A (ja) * | 1994-05-31 | 1995-12-19 | Tonen Corp | パティキュレート低減用添加剤及び該添加剤を用いたディーゼルエンジン用燃料組成物 |
CN1222139A (zh) * | 1996-06-13 | 1999-07-07 | 里奥药物制品有限公司 | 多元醇琥珀酸酯及其药物制剂 |
GB9612331D0 (en) * | 1996-06-13 | 1996-08-14 | Leo Pharm Prod Ltd | Chemical compounds |
US6221641B1 (en) | 1998-07-02 | 2001-04-24 | Leland Stanford Junior University | Method for making polyketides |
AUPR059400A0 (en) | 2000-10-06 | 2000-11-02 | Bar-Ilan University | Formaldehyde-releasing prodrugs |
WO2002102820A1 (en) * | 2001-06-20 | 2002-12-27 | Nuevolution A/S | Nucleoside derivatives for library preparation |
US7468383B2 (en) * | 2005-02-11 | 2008-12-23 | Cephalon, Inc. | Proteasome inhibitors and methods of using the same |
KR100791844B1 (ko) | 2006-06-30 | 2008-01-07 | 주식회사유한양행 | 메트포르민 또는 그의 염을 함유하는 서방성 제제 및 그의제조방법 |
KR101069502B1 (ko) | 2006-10-31 | 2011-09-30 | (주)아모레퍼시픽 | 비만 및 당뇨병 개선용 경구용 조성물 |
US20120308646A1 (en) * | 2007-01-18 | 2012-12-06 | Hesheng Zhang | Tetracyclic anthraquinones possessing anti-cancer properties |
JP2010522762A (ja) | 2007-03-26 | 2010-07-08 | サルトリア・フアーマシユーテイカルズ・エル・エル・シー | 糖尿病の治療のための方法及びプロブコール誘導体の組成物 |
US8410139B2 (en) * | 2009-10-07 | 2013-04-02 | Bristol-Myers Squibb Company | Prodrugs of a piperidinyl derivative as modulators of chemokine receptor activity |
IT1406068B1 (it) | 2010-07-22 | 2014-02-06 | Medestea Int Spa | Polidesossiribonucleotidi (pdrn) per l'impiego nel trattamento di condizioni di acidosi e composizioni a base di polidesossiribonucleotidi per il suddetto impiego |
JP2014024772A (ja) | 2012-07-25 | 2014-02-06 | Univ Of Tokyo | ミトコンドリアのatp産生能昂進剤 |
WO2014053857A1 (en) | 2012-10-05 | 2014-04-10 | Mitopharm Ltd | Protected succinates for enhancing mitochondrial atp-production |
MA39857A (fr) | 2014-04-08 | 2017-02-15 | Neurovive Pharmaceutical Ab | Promédicaments à base de succinate destinés à être utilisés dans le traitement de l'acidose lactique ou d'effets secondaires induits par un médicament dus à une déficience liée au complexe i de la phosphorylation oxydative mitochondriale |
EA035678B1 (ru) * | 2014-04-08 | 2020-07-24 | Ньюроувив Фармасьютикал Аб | Новые клеточно-проницаемые сукцинатные соединения |
WO2015155230A1 (en) | 2014-04-08 | 2015-10-15 | Neurovive Pharmaceutical Ab | Prodrugs of succinic acid for increasing atp production |
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2015
- 2015-04-08 EA EA201692017A patent/EA035678B1/ru not_active IP Right Cessation
- 2015-04-08 EP EP18175718.8A patent/EP3391941B1/en active Active
- 2015-04-08 MX MX2016012691A patent/MX2016012691A/es unknown
- 2015-04-08 LT LTEP18175718.8T patent/LT3391941T/lt unknown
- 2015-04-08 US US15/128,480 patent/US11147789B2/en active Active
- 2015-04-08 TR TR2018/10411T patent/TR201810411T4/tr unknown
- 2015-04-08 SG SG11201607907PA patent/SG11201607907PA/en unknown
- 2015-04-08 DK DK15714820.6T patent/DK3129016T3/en active
- 2015-04-08 PL PL15714820T patent/PL3129016T3/pl unknown
- 2015-04-08 ES ES18175718T patent/ES2953522T3/es active Active
- 2015-04-08 CA CA2944565A patent/CA2944565C/en active Active
- 2015-04-08 SI SI201530356T patent/SI3129016T1/sl unknown
- 2015-04-08 LT LTEP15714820.6T patent/LT3129016T/lt unknown
- 2015-04-08 WO PCT/EP2015/057606 patent/WO2015155231A1/en active Application Filing
- 2015-04-08 EP EP15714820.6A patent/EP3129016B1/en active Active
- 2015-04-08 MA MA39855A patent/MA39855B1/fr unknown
- 2015-04-08 PT PT181757188T patent/PT3391941T/pt unknown
- 2015-04-08 ES ES15714820.6T patent/ES2683860T3/es active Active
- 2015-04-08 PT PT15714820T patent/PT3129016T/pt unknown
- 2015-04-08 KR KR1020167030753A patent/KR102322543B1/ko active IP Right Grant
- 2015-04-08 JP JP2016561677A patent/JP7082861B6/ja active Active
- 2015-04-08 CN CN201580021727.0A patent/CN106458957B/zh active Active
- 2015-04-08 RS RS20180921A patent/RS57624B1/sr unknown
- 2015-04-08 AU AU2015243346A patent/AU2015243346C9/en active Active
- 2015-04-08 MA MA44092A patent/MA44092B1/fr unknown
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2016
- 2016-09-19 IL IL247904A patent/IL247904B/en active IP Right Grant
- 2016-09-23 ZA ZA2016/06608A patent/ZA201606608B/en unknown
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2018
- 2018-07-16 HR HRP20181126TT patent/HRP20181126T1/hr unknown
- 2018-08-27 CY CY181100892T patent/CY1120650T1/el unknown
- 2018-11-08 HK HK18114264.0A patent/HK1255109A1/zh unknown
- 2018-12-19 AU AU2018282308A patent/AU2018282308B2/en active Active
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2020
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2021
- 2021-07-20 JP JP2021119885A patent/JP2021169519A/ja active Pending
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- 2021-09-14 US US17/474,482 patent/US20210401792A1/en active Pending
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