JP2021059585A5 - - Google Patents
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- JP2021059585A5 JP2021059585A5 JP2020216289A JP2020216289A JP2021059585A5 JP 2021059585 A5 JP2021059585 A5 JP 2021059585A5 JP 2020216289 A JP2020216289 A JP 2020216289A JP 2020216289 A JP2020216289 A JP 2020216289A JP 2021059585 A5 JP2021059585 A5 JP 2021059585A5
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- Prior art keywords
- immunoglobulin
- fragment
- conjugate
- drug composition
- linked
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 102000018071 Immunoglobulin Fc Fragments Human genes 0.000 claims 22
- 108010091135 Immunoglobulin Fc Fragments Proteins 0.000 claims 22
- 239000000203 mixture Substances 0.000 claims 17
- 102000004196 processed proteins & peptides Human genes 0.000 claims 17
- 229920001184 polypeptide Polymers 0.000 claims 16
- 230000000975 bioactive effect Effects 0.000 claims 11
- 108060003951 Immunoglobulin Proteins 0.000 claims 10
- 102000018358 immunoglobulin Human genes 0.000 claims 10
- -1 oxintomodulin Chemical compound 0.000 claims 8
- 229940079593 drug Drugs 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 6
- 239000003509 long acting drug Substances 0.000 claims 6
- 230000002459 sustained effect Effects 0.000 claims 5
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| DK3127923T3 (da) * | 2014-03-31 | 2021-11-22 | Hanmi Pharm Ind Co Ltd | Fremgangsmåde til forbedring af oppløselighed af protein og peptid ved hjælp af immunoglobulin-fc-fragment-binding |
| JP2018508504A (ja) * | 2015-02-17 | 2018-03-29 | ハンミ ファーマシューティカル カンパニー リミテッド | 持続型インスリンまたはインスリンアナログ結合体 |
| EP3313875A4 (en) * | 2015-06-24 | 2018-12-26 | Board of Regents of the University of Texas System | Methods and compositions for treatment of symptoms associated with intracranial hemorrhage |
| EP3344299B1 (en) * | 2015-09-01 | 2021-08-11 | Baxter International Inc | Hemostatic material |
| TW201718629A (zh) * | 2015-09-25 | 2017-06-01 | 韓美藥品股份有限公司 | 包含多個生理多肽及免疫球蛋白Fc區之蛋白質接合物 |
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