|
RU2572826C2
(ru)
|
2008-12-02 |
2016-01-20 |
Чиралджен, Лтд. |
Способ синтеза модифицированных по атому фосфора нуклеиновых кислот
|
|
CA2767253A1
(en)
|
2009-07-06 |
2011-01-13 |
Ontorii, Inc. |
Novel nucleic acid prodrugs and methods of use thereof
|
|
JP5868324B2
(ja)
|
2010-09-24 |
2016-02-24 |
株式会社Wave Life Sciences Japan |
不斉補助基
|
|
AU2012284265B2
(en)
|
2011-07-19 |
2017-08-17 |
Wave Life Sciences Ltd. |
Methods for the synthesis of functionalized nucleic acids
|
|
SG11201500239VA
(en)
|
2012-07-13 |
2015-03-30 |
Wave Life Sciences Japan |
Asymmetric auxiliary group
|
|
ES2917473T3
(es)
|
2014-01-16 |
2022-07-08 |
Wave Life Sciences Ltd |
Diseño quiral
|
|
US11583593B2
(en)
|
2016-01-14 |
2023-02-21 |
Synthis Therapeutics, Inc. |
Antibody-ALK5 inhibitor conjugates and their uses
|
|
JP2019513371A
(ja)
|
2016-04-01 |
2019-05-30 |
アビディティー バイオサイエンシーズ エルエルシー |
核酸ポリペプチド組成物とその使用
|
|
CN109310765A
(zh)
*
|
2016-06-20 |
2019-02-05 |
领先基因生物技术股份有限公司 |
抗体-药物偶联物
|
|
MX2019008199A
(es)
|
2017-01-06 |
2019-11-25 |
Avidity Biosciences Llc |
Composiciones de acido nucleico polipeptido y metodos de induccion de la omision de exon.
|
|
GB201711809D0
(en)
|
2017-07-21 |
2017-09-06 |
Governors Of The Univ Of Alberta |
Antisense oligonucleotide
|
|
WO2019071028A1
(en)
*
|
2017-10-04 |
2019-04-11 |
Avidity Biosciences Llc |
NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF
|
|
JP7506601B2
(ja)
|
2017-12-06 |
2024-06-26 |
アビディティー バイオサイエンシーズ,インク. |
筋萎縮症と筋緊張性ジストロフィーを処置するための組成物および方法
|
|
EP3552631A1
(en)
*
|
2018-04-10 |
2019-10-16 |
Inatherys |
Antibody-drug conjugates and their uses for the treatment of cancer
|
|
CN112930193A
(zh)
*
|
2018-08-02 |
2021-06-08 |
达因疗法公司 |
肌肉靶向复合物及其在治疗肌肉萎缩中的用途
|
|
EP3830130A4
(en)
*
|
2018-08-02 |
2022-05-18 |
Dyne Therapeutics, Inc. |
Muscle targeting complexes and uses thereof for treating centronuclear myopathy
|
|
KR20210086601A
(ko)
*
|
2018-08-02 |
2021-07-08 |
다인 세라퓨틱스, 인크. |
근육 표적화 복합체 및 프리드라이히 운동실조를 치료하기 위한 그의 용도
|
|
JP2021533197A
(ja)
*
|
2018-08-02 |
2021-12-02 |
ダイン セラピューティクス, インコーポレーテッドDyne Therapeutics, Inc. |
ポンペ病を処置するための筋標的化複合体およびそれらの使用
|
|
CA3108328A1
(en)
*
|
2018-08-02 |
2020-02-06 |
Dyne Therapeutics, Inc. |
Muscle targeting complexes and uses thereof for treating fibrodysplasia ossificans progressiva
|
|
WO2020028842A1
(en)
*
|
2018-08-02 |
2020-02-06 |
Dyne Therapeutics, Inc. |
Muscle targeting complexes and uses thereof for treating hypertrophic cardiomyopathy
|
|
US11911484B2
(en)
|
2018-08-02 |
2024-02-27 |
Dyne Therapeutics, Inc. |
Muscle targeting complexes and uses thereof for treating myotonic dystrophy
|
|
IL321905A
(en)
*
|
2018-08-02 |
2025-09-01 |
Dyne Therapeutics Inc |
Muscle-targeted conjugates and their uses in the treatment of myotonia dystrophica
|
|
JP7576542B2
(ja)
*
|
2018-08-02 |
2024-10-31 |
ダイン セラピューティクス,インコーポレーテッド |
筋標的化複合体およびそれらの使用
|
|
EP3829595A4
(en)
|
2018-08-02 |
2022-08-24 |
Dyne Therapeutics, Inc. |
MUSCLE-DIRECTED COMPLEXES AND USES THEREOF IN THE TREATMENT OF DYSTROPHINOPATHIES
|
|
US11168141B2
(en)
|
2018-08-02 |
2021-11-09 |
Dyne Therapeutics, Inc. |
Muscle targeting complexes and uses thereof for treating dystrophinopathies
|
|
US20220193250A1
(en)
|
2018-08-02 |
2022-06-23 |
Dyne Therapeutics, Inc. |
Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
|
|
US12370264B1
(en)
|
2018-08-02 |
2025-07-29 |
Dyne Therapeutics, Inc. |
Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
|
|
US12097263B2
(en)
|
2018-08-02 |
2024-09-24 |
Dyne Therapeutics, Inc. |
Muscle targeting complexes and uses thereof for treating myotonic dystrophy
|
|
US12018087B2
(en)
|
2018-08-02 |
2024-06-25 |
Dyne Therapeutics, Inc. |
Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
|
|
US12497615B2
(en)
|
2019-04-25 |
2025-12-16 |
Avidity Biosciences, Inc. |
Nucleic acid compositions and methods of multi-exon skipping
|
|
JP7592034B2
(ja)
|
2019-06-06 |
2024-11-29 |
アビディティー バイオサイエンシーズ,インク. |
核酸ポリペプチド組成物およびその使用
|
|
KR20220019259A
(ko)
|
2019-06-06 |
2022-02-16 |
어비디티 바이오사이언시스 인크. |
Una 아미다이트 및 이의 용도
|
|
CN119874910A
(zh)
*
|
2019-06-07 |
2025-04-25 |
达因疗法公司 |
制备蛋白质-寡核苷酸复合物的方法
|
|
WO2020256721A1
(en)
*
|
2019-06-19 |
2020-12-24 |
Synthis, Llc |
Antib0dy-alk5 inhibitor conjugates and their uses
|
|
CN114786682B
(zh)
|
2019-10-14 |
2024-07-16 |
Aro生物疗法公司 |
结合cd71的纤维粘连蛋白iii型结构域
|
|
AU2021206234A1
(en)
*
|
2020-01-10 |
2022-09-01 |
Dyne Therapeutics, Inc. |
Muscle targeting complexes and uses thereof for treating myotonic dystrophy
|
|
KR20220125801A
(ko)
*
|
2020-01-10 |
2022-09-14 |
다인 세라퓨틱스, 인크. |
근육 표적화 복합체 및 안면견갑상완 근육 이영양증을 치료하기 위한 그의 용도
|
|
CA3163283A1
(en)
*
|
2020-01-10 |
2021-07-15 |
Romesh R. Subramanian |
Muscle targeting complexes and uses thereof for modulation of genes associated with muscle health
|
|
CN115427059A
(zh)
*
|
2020-01-31 |
2022-12-02 |
达因疗法公司 |
抗转铁蛋白受体(tfr)抗体及其用途
|
|
WO2021154477A1
(en)
*
|
2020-01-31 |
2021-08-05 |
Dyne Therapeutics, Inc. |
Anti-transferrin receptor (tfr) antibody and uses thereof
|
|
US11555190B2
(en)
|
2020-03-19 |
2023-01-17 |
Avidity Biosciences, Inc. |
Compositions and methods of treating Facioscapulohumeral muscular dystrophy
|
|
AU2021241682B2
(en)
|
2020-03-27 |
2026-02-12 |
Avidity Biosciences, Inc. |
Compositions and methods of treating muscle dystrophy
|
|
JP2024501872A
(ja)
*
|
2020-12-31 |
2024-01-16 |
ダイン セラピューティクス,インコーポレーテッド |
顔面肩甲上腕筋ジストロフィーを処置するための筋標的化複合体およびそれらの使用
|
|
JP7792397B2
(ja)
|
2021-03-26 |
2025-12-25 |
株式会社フジミインコーポレーテッド |
研磨方法および半導体基板の製造方法、ならびに研磨用組成物セット
|
|
CA3214552A1
(en)
|
2021-04-14 |
2022-10-20 |
Russell C. Addis |
Cd71 binding fibronectin type iii domains
|
|
BR112023021318A2
(pt)
*
|
2021-04-14 |
2023-12-19 |
Aro Biotherapeutics Company |
Conjugados de domínio fn3-sirna e usos dos mesmos
|
|
US11633498B2
(en)
|
2021-07-09 |
2023-04-25 |
Dyne Therapeutics, Inc. |
Muscle targeting complexes and uses thereof for treating myotonic dystrophy
|
|
US11672872B2
(en)
|
2021-07-09 |
2023-06-13 |
Dyne Therapeutics, Inc. |
Anti-transferrin receptor antibody and uses thereof
|
|
IL309936A
(en)
|
2021-07-09 |
2024-03-01 |
Dyne Therapeutics Inc |
Muscle targeting complexes and formulations for the treatment of dystrophinopathy
|
|
US11969475B2
(en)
|
2021-07-09 |
2024-04-30 |
Dyne Therapeutics, Inc. |
Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
|
|
US11638761B2
(en)
|
2021-07-09 |
2023-05-02 |
Dyne Therapeutics, Inc. |
Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy
|
|
US11771776B2
(en)
|
2021-07-09 |
2023-10-03 |
Dyne Therapeutics, Inc. |
Muscle targeting complexes and uses thereof for treating dystrophinopathies
|
|
US20240390508A1
(en)
|
2021-08-21 |
2024-11-28 |
Takeda Pharmaceutical Company Limited |
Human transferrin receptor binding peptide-drug conjugate
|
|
US20240366775A1
(en)
|
2021-08-24 |
2024-11-07 |
Peptidream Inc. |
Human transferrin receptor binding antibody-peptide conjugate
|
|
EP4396352A4
(en)
|
2021-09-01 |
2025-10-01 |
Ionis Pharmaceuticals Inc |
COMPOUNDS AND METHODS FOR REDUCING DMPK EXPRESSION
|
|
EP4396231A1
(en)
|
2021-09-01 |
2024-07-10 |
Biogen MA Inc. |
Anti-transferrin receptor antibodies and uses thereof
|
|
MX2024003266A
(es)
|
2021-09-16 |
2024-04-03 |
Avidity Biosciences Inc |
Composiciones y metodos de tratamiento de la distrofia muscular facioescapulohumeral.
|
|
US11939391B2
(en)
|
2021-12-06 |
2024-03-26 |
MedAbome, Inc. |
Anti-TfR1 antibody MAb11-22.1 conjugates for cancer treatment
|
|
US12071621B2
(en)
|
2022-04-05 |
2024-08-27 |
Avidity Biosciences, Inc. |
Anti-transferrin receptor antibody-PMO conjugates for inducing DMD exon 44 skipping
|
|
US20250339553A1
(en)
|
2022-04-15 |
2025-11-06 |
Dyne Therapeutics, Inc. |
Muscle targeting complexes and formulations for treating myotonic dystrophy
|
|
PE20260008A1
(es)
|
2023-03-08 |
2026-01-06 |
Biogen Ma Inc |
Anticuerpos anti-receptor de transferrina y usos de estos
|
|
WO2025007063A1
(en)
*
|
2023-06-30 |
2025-01-02 |
Avidity Biosciences, Inc. |
Compositions and methods of using pln-targeting antibody-oligonucleotide conjugates
|
|
AU2024299328A1
(en)
|
2023-07-21 |
2026-01-22 |
Marrow Therapeutics, Inc. |
Hematopoietic cell targeting conjugates and related methods
|
|
WO2025090898A1
(en)
|
2023-10-26 |
2025-05-01 |
Biogen Ma Inc. |
Anti-transferrin receptor antibodies and uses thereof cross reference to related applications
|
|
WO2025090121A1
(en)
*
|
2023-10-27 |
2025-05-01 |
Yale University |
Conjugate and methods of treatment
|
|
WO2025168041A1
(zh)
*
|
2024-02-08 |
2025-08-14 |
成都新泽利医药科技有限公司 |
治疗2型炎症性疾病的组合物和方法
|
|
WO2025207959A1
(en)
|
2024-03-27 |
2025-10-02 |
Biogen Ma Inc. |
Anti-transferrin receptor antibodies and uses thereof
|
|
CN118897089B
(zh)
*
|
2024-08-09 |
2026-02-17 |
山西医科大学 |
Sarcolipin在早期无创诊断I型射血分数保留性心衰中的应用
|