JP2020536066A5 - - Google Patents

Download PDF

Info

Publication number
JP2020536066A5
JP2020536066A5 JP2020517921A JP2020517921A JP2020536066A5 JP 2020536066 A5 JP2020536066 A5 JP 2020536066A5 JP 2020517921 A JP2020517921 A JP 2020517921A JP 2020517921 A JP2020517921 A JP 2020517921A JP 2020536066 A5 JP2020536066 A5 JP 2020536066A5
Authority
JP
Japan
Prior art keywords
cancer
drug
pharmaceutical combination
cancers
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020517921A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020536066A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/053542 external-priority patent/WO2019067978A1/en
Publication of JP2020536066A publication Critical patent/JP2020536066A/ja
Publication of JP2020536066A5 publication Critical patent/JP2020536066A5/ja
Priority to JP2023036980A priority Critical patent/JP2023076826A/ja
Pending legal-status Critical Current

Links

JP2020517921A 2017-09-30 2018-09-28 癌を治療するための併用療法 Pending JP2020536066A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023036980A JP2023076826A (ja) 2017-09-30 2023-03-09 癌を治療するための併用療法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762566398P 2017-09-30 2017-09-30
US62/566,398 2017-09-30
US201762578298P 2017-10-27 2017-10-27
US62/578,298 2017-10-27
US201862654024P 2018-04-06 2018-04-06
US62/654,024 2018-04-06
PCT/US2018/053542 WO2019067978A1 (en) 2017-09-30 2018-09-28 POLYTHERAPIES FOR THE TREATMENT OF CANCER

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023036980A Division JP2023076826A (ja) 2017-09-30 2023-03-09 癌を治療するための併用療法

Publications (2)

Publication Number Publication Date
JP2020536066A JP2020536066A (ja) 2020-12-10
JP2020536066A5 true JP2020536066A5 (https=) 2021-11-11

Family

ID=65903287

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020517921A Pending JP2020536066A (ja) 2017-09-30 2018-09-28 癌を治療するための併用療法
JP2023036980A Pending JP2023076826A (ja) 2017-09-30 2023-03-09 癌を治療するための併用療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023036980A Pending JP2023076826A (ja) 2017-09-30 2023-03-09 癌を治療するための併用療法

Country Status (13)

Country Link
US (1) US11661453B2 (https=)
EP (1) EP3697442A4 (https=)
JP (2) JP2020536066A (https=)
KR (1) KR20200086664A (https=)
CN (1) CN111372607A (https=)
AU (1) AU2018338901A1 (https=)
BR (1) BR112020006286A2 (https=)
CA (1) CA3076515A1 (https=)
IL (1) IL273395A (https=)
MA (1) MA50409A (https=)
MX (1) MX2020003770A (https=)
SG (1) SG11202002862RA (https=)
WO (1) WO2019067978A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019533458A (ja) * 2016-11-01 2019-11-21 アナプティスバイオ インコーポレイティッド プログラム死1(pd−1)に対する抗体
AU2018206481B2 (en) 2017-01-09 2025-02-27 Tesaro, Inc. Methods of treating cancer with anti-PD-1 antibodies
CN110944638A (zh) 2017-03-27 2020-03-31 特沙诺有限公司 尼拉帕尼组合物
MA48475A (fr) 2017-04-24 2020-03-04 Tesaro Inc Procédés de fabrication de niraparib
TW202444417A (zh) 2017-05-09 2024-11-16 美商提薩羅有限公司 治療癌症的組合療法
KR20200005662A (ko) 2017-05-18 2020-01-15 테사로, 인코포레이티드 암을 치료하기 위한 조합 요법
TWI843707B (zh) 2017-09-26 2024-06-01 美商提薩羅有限公司 尼拉帕尼(niraparib)調配物
MX2020003770A (es) 2017-09-30 2020-07-29 Tesaro Inc Terapias de combinacion para tratar cancer.
EA202090655A1 (ru) 2017-10-06 2020-12-07 Тесаро, Инк. Комбинированные терапевтические средства и их применение
AU2019351522B2 (en) * 2018-09-29 2025-10-30 Guangzhou Burning Rock Dx Co., Ltd. Second generation sequencing-based method for detecting microsatellite stability and genome changes by means of plasma
EP4225383A4 (en) * 2020-10-08 2024-12-11 Kumquat Biosciences Inc. MODULATORS OF CELLULAR PROLIFERATION AND THEIR USES
MA63136A1 (fr) * 2021-05-18 2024-06-28 Onconic Therapeutics Inc. Agent thérapeutique contre le cancer résistant à un inhibiteur de parp
CN113234160B (zh) * 2021-05-26 2022-05-27 广州爱思迈生物医药科技有限公司 一种抗pd-1抗体及其应用
WO2024259248A2 (en) * 2023-06-15 2024-12-19 Memorial Sloan-Kettering Cancer Center Methods for treating cancer patients with homologous recombination deficiency based on pathognomonic long molecule footprints of backup repair pathways
KR20250087969A (ko) 2023-12-08 2025-06-17 주식회사 이앤지테크 팝업댓글 플랫폼을 활용한 소상공인 업소안내 증강현실 시스템 및 그 구동방법

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2059571T3 (es) 1988-01-19 1994-11-16 Takeda Chemical Industries Ltd Fumagilina como agente angiostatico.
CA1329771C (en) 1988-09-01 1994-05-24 Shoji Kishimoto Angiogenesis inhibitory agent
AU2003281200A1 (en) 2002-07-03 2004-01-23 Tasuku Honjo Immunopotentiating compositions
US9707302B2 (en) 2013-07-23 2017-07-18 Immunomedics, Inc. Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
CA2647545C (en) 2006-04-03 2016-02-23 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Amide substituted indazole and benzotriazole derivatives as poly(adp-ribose)polymerase (parp) inhibitors
JP4611444B2 (ja) 2007-01-10 2011-01-12 イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー ポリ(adp−リボース)ポリメラーゼ(parp)阻害剤としてのアミド置換インダゾール
BR122017025062B8 (pt) 2007-06-18 2021-07-27 Merck Sharp & Dohme anticorpo monoclonal ou fragmento de anticorpo para o receptor de morte programada humano pd-1, polinucleotídeo e composição compreendendo o referido anticorpo ou fragmento
EP2217244A4 (en) 2007-11-12 2011-08-31 Bipar Sciences Inc TREATMENT OF NUTRITIONAL CANCER AND EGG CANCER WITH A PARP INHIBITOR ALONE OR IN COMBINATION WITH ANTITUMOROUS MEDICINES
US7732491B2 (en) 2007-11-12 2010-06-08 Bipar Sciences, Inc. Treatment of breast cancer with a PARP inhibitor alone or in combination with anti-tumor agents
WO2009087474A2 (en) 2008-01-08 2009-07-16 Akthelia Pharmaceuticals Agonists for antimicrobial peptide systems
KR101653548B1 (ko) 2008-01-08 2016-09-02 머크 샤프 앤드 돔 리미티드 2-{4-[(3s)-피페리딘-3-일]페닐}-2h-인다졸-7-카복스아미드의 약제학적으로 허용되는 염
EP3255060A1 (en) 2008-12-09 2017-12-13 F. Hoffmann-La Roche AG Anti-pd-l1 antibodies and their use to enhance t-cell function
CN102307475A (zh) * 2009-02-04 2012-01-04 彼帕科学公司 用与生长因子抑制剂组合的parp抑制剂治疗肺癌
PL2504364T3 (pl) 2009-11-24 2017-12-29 Medimmune Limited Ukierunkowane środki wiążące przeciwko B7-H1
WO2011153383A1 (en) 2010-06-04 2011-12-08 Bipar Science, Inc. Methods of treating platinum-resistant recurrent ovarian cancer with 4-iodo-3-nitrobenzamide in combination with an anti-metabolite and a platinum compound
EP3012329B1 (en) 2010-06-18 2017-10-25 Myriad Genetics, Inc. Methods and materials for assessing loss of heterozygosity
WO2012027224A1 (en) 2010-08-24 2012-03-01 Dana-Farber Cancer Institute, Inc. Methods for predicting anti-cancer response
CA2742342A1 (en) 2011-02-12 2012-08-12 Baylor Research Institute Msh3 expression status determines the responsiveness of cancer cells to the chemotherapeutic treatment with parp inhibitors and platinum drugs
KR101764096B1 (ko) 2011-11-28 2017-08-02 메르크 파텐트 게엠베하 항-pd-l1 항체 및 그의 용도
WO2013182645A1 (en) 2012-06-07 2013-12-12 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
EP2928473B1 (en) 2012-12-07 2017-06-28 Merck Sharp & Dohme Corp. Regioselective n-2 arylation of indazoles
US9738915B2 (en) 2012-12-07 2017-08-22 Merck Sharp & Dohme Corp. Biocatalytic transamination process
US9850542B2 (en) 2013-03-04 2017-12-26 Board Of Regents, The University Of Texas System Gene signature to predict homologous recombination (HR) deficient cancer
US20150071910A1 (en) 2013-03-15 2015-03-12 Genentech, Inc. Biomarkers and methods of treating pd-1 and pd-l1 related conditions
SMT202100065T1 (it) 2013-05-02 2021-03-15 Anaptysbio Inc Anticorpi diretti contro la proteina della morte programmata (pd-1)
WO2015086473A1 (en) 2013-12-09 2015-06-18 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
CN105917007A (zh) 2014-01-16 2016-08-31 克洛维斯肿瘤有限公司 Parp抑制剂用以治疗显示杂合性丧失的乳腺癌或卵巢癌患者的用途
WO2015116868A2 (en) * 2014-01-29 2015-08-06 Caris Mpi, Inc. Molecular profiling of immune modulators
WO2015184145A1 (en) 2014-05-28 2015-12-03 Eisai R&D Management Co., Ltd. Use of eribulin and poly (adp ribose) polymerase (parp) inhibitors as combination therapy for the treatment of cancer
US20150344968A1 (en) 2014-05-30 2015-12-03 Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center Methods for determining parp inhibitor and platinum resistance in cancer therapy
US20160160294A1 (en) 2014-12-08 2016-06-09 Tesaro Methods and materials for predicting response to niraparib
MA41463A (fr) 2015-02-03 2017-12-12 Anaptysbio Inc Anticorps dirigés contre le gène d'activation 3 des lymphocytes (lag-3)
FI3277321T3 (fi) 2015-04-01 2024-10-31 Anaptysbio Inc T-soluimmunoglobuliinia ja musiiniproteiini 3:a (tim-3) vastaan suunnattuja vasta-aineita
JP2018514550A (ja) 2015-04-28 2018-06-07 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company 抗pd−1抗体および抗ctla−4抗体を使用するpd−l1陰性黒色腫の処置
MX2017015937A (es) 2015-06-08 2018-12-11 Genentech Inc Métodos de tratamiento del cáncer con anticuerpos anti-ox40 y antagonistas de unión al eje de pd-1.
JP6980980B2 (ja) 2015-06-25 2021-12-15 イミューノメディクス、インコーポレイテッドImmunomedics, Inc. 抗hla‐drまたは抗trop‐2抗体と微小管阻害剤、parp阻害剤、ブルトンキナーゼ阻害剤またはホスホイノシチド3‐キナーゼ阻害剤との併用は癌の治療効果を有意に改善する
JP7042739B2 (ja) 2015-08-20 2022-03-28 イプセン バイオファーム リミティド 癌処置のためのリポソーム型イリノテカン及びparp阻害薬を使用する併用療法
SG11201803462PA (en) 2015-10-26 2018-05-30 Medivation Tech Llc Treatment of small cell lung cancer with a parp inhibitor
US20210322415A1 (en) 2016-02-15 2021-10-21 Astrazeneca Ab Methods comprising fixed intermittent dosing of cediranib
SG11201811564QA (en) 2016-06-29 2019-01-30 Tesaro Inc Methods of treating ovarian cancer
CN110087730B (zh) * 2016-09-27 2023-03-28 百济神州(苏州)生物科技有限公司 使用包含parp抑制剂的组合产品治疗癌症
MX2019005116A (es) 2016-11-01 2019-11-12 Anaptysbio Inc Anticuerpos dirigidos contra la proteina de inmunoglobulina de linfocitos t y de mucina 3 (tim-3).
JP2019533458A (ja) 2016-11-01 2019-11-21 アナプティスバイオ インコーポレイティッド プログラム死1(pd−1)に対する抗体
AU2018206481B2 (en) 2017-01-09 2025-02-27 Tesaro, Inc. Methods of treating cancer with anti-PD-1 antibodies
WO2018129553A1 (en) 2017-01-09 2018-07-12 Tesaro, Inc. Methods of treating cancer with anti-tim-3 antibodies
KR20190130625A (ko) 2017-03-27 2019-11-22 테사로, 인코포레이티드 니라파립 제제
CN110944638A (zh) 2017-03-27 2020-03-31 特沙诺有限公司 尼拉帕尼组合物
MA48475A (fr) 2017-04-24 2020-03-04 Tesaro Inc Procédés de fabrication de niraparib
SG11201909395TA (en) 2017-04-27 2019-11-28 Tesaro Inc Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof
TW202444417A (zh) 2017-05-09 2024-11-16 美商提薩羅有限公司 治療癌症的組合療法
KR20200005662A (ko) 2017-05-18 2020-01-15 테사로, 인코포레이티드 암을 치료하기 위한 조합 요법
US20200129482A1 (en) 2017-06-26 2020-04-30 Abbvie Inc. Treatment of non-small cell lung cancer
TWI843707B (zh) 2017-09-26 2024-06-01 美商提薩羅有限公司 尼拉帕尼(niraparib)調配物
MX2020003770A (es) 2017-09-30 2020-07-29 Tesaro Inc Terapias de combinacion para tratar cancer.
EA202090655A1 (ru) 2017-10-06 2020-12-07 Тесаро, Инк. Комбинированные терапевтические средства и их применение
US20210106574A1 (en) 2017-12-27 2021-04-15 Tesaro, Inc. Methods of Treating Cancer
CN111918667A (zh) 2018-02-05 2020-11-10 特沙诺有限公司 儿科尼拉帕尼配制剂和儿科治疗方法
EA201992594A1 (ru) 2018-03-26 2020-03-20 Тесаро, Инк. Комбинированные терапии для лечения рака
US11970530B2 (en) 2020-08-13 2024-04-30 Astrazeneca Ab Methods of treating homologous recombination deficient cancer

Similar Documents

Publication Publication Date Title
JP2020536066A5 (https=)
JP2020519621A5 (https=)
JP2017533266A5 (https=)
JP2021102627A5 (https=)
JP2020536869A5 (https=)
RU2016130986A (ru) Ингибитор киназы и его применение
JP2020503364A5 (https=)
JP2017095457A5 (https=)
CN107548391A (zh) 嘧啶或吡啶类化合物、其制备方法和医药用途
JPWO2023190748A5 (https=)
JP2020504141A5 (https=)
JP2018504418A5 (https=)
JP2018070648A5 (https=)
JP2019501204A5 (https=)
JPWO2019189732A5 (https=)
JP2019506403A5 (https=)
JP2016502504A5 (https=)
JP2016528246A5 (https=)
Bullard Dunn et al. Evolving therapies and FAK inhibitors for the treatment of cancer
RU2020142739A (ru) Ингибиторы mdm2 и их комбинации
JP2015518040A5 (https=)
JP2015534580A5 (https=)
CA2649549A1 (en) Methods of treating cell proliferative disorders by using pyrimidinediamine compounds
JP2014518544A5 (https=)
RU2018102963A (ru) Производные анилинпиримидина и их применения