|
US922078A
(en)
|
1909-03-01 |
1909-05-18 |
Charles Burwell Benson |
Tongue-depressor.
|
|
DK166650B1
(da)
|
1991-03-15 |
1993-06-28 |
Aarhus Oliefabrik As |
Fedtbaser samt anvendelse af disse i kosmetiske og farmaceutiske emulsionsprodukter
|
|
US5977174A
(en)
|
1997-11-26 |
1999-11-02 |
Neuromedica, Inc. |
Cholinergic compositions and uses thereof
|
|
US5985936A
(en)
|
1997-12-18 |
1999-11-16 |
Forbes Medi-Tech, Inc. |
Method of preventing and delaying onset of Alzheimer's disease and composition therefor
|
|
CA2330916C
(en)
|
1998-05-19 |
2011-04-05 |
Research Development Foundation |
Triterpene compositions and methods for use thereof
|
|
DE60039232D1
(de)
|
1999-04-27 |
2008-07-31 |
Forbes Medi Tech Inc |
Verfahren zur Herstellung einer Phytosterolzusammensetzung
|
|
CN1129613C
(zh)
|
1999-12-24 |
2003-12-03 |
中国科学院上海药物研究所 |
夹竹桃花多糖及其制备方法和应用
|
|
US6629835B2
(en)
*
|
2000-08-01 |
2003-10-07 |
Metaproteomics, Llc |
Combinations of diterpene triepoxide lactones and ditepene lactones or triterpenes for synergistic inhibition of cyclooxygenase-2
|
|
US20020077350A1
(en)
|
2000-08-01 |
2002-06-20 |
Ashni Naturaceuticals, Inc. |
Compositions exhibiting synergistic inhibition of the expression and/or activity of clyclooxygenase-2
|
|
AU8494601A
(en)
|
2000-08-18 |
2002-03-04 |
Univ Illinois |
Prodrugs of betulinic acid derivatives for the treatment of cancer and HIV
|
|
DE60204078T2
(de)
|
2001-04-09 |
2006-01-26 |
Loders Croklaan B.V. |
Konzentrat von Triterpenen
|
|
EP2567625A1
(en)
|
2001-05-11 |
2013-03-13 |
University Of Ottawa |
Preparation containing betulinic acid, obtained from a plant of the family Marcgraviaceae
|
|
WO2003099011A1
(en)
|
2002-05-28 |
2003-12-04 |
Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. |
Cardiac glycosides to treat cystic fibrosis and other il-8 dependent disorders
|
|
US20070249711A1
(en)
|
2003-10-10 |
2007-10-25 |
Wonrack Choi |
Triterpene Compounds which are Effective on Improvement of Brain Function
|
|
DE602004014974D1
(de)
*
|
2003-12-19 |
2008-08-21 |
Lipid Nutrition Bv |
Verwendung von zusammensetzungen mit oleansäure und ursolsäure zur herstellung eines medikaments zur behandlung von überempfindlichkeit und hyperreaktivität
|
|
BRPI0508854A
(pt)
|
2004-03-17 |
2007-08-28 |
Panacos Pharmaceuticals Inc |
sais farmacêuticos de ácido-3-o-(3',3'-dimetilsuccinil) betulìnico
|
|
US7118508B2
(en)
|
2004-07-28 |
2006-10-10 |
General Motors Corporation |
Planetary transmissions having three interconnected gear members and clutched input members
|
|
EP1812010A2
(en)
|
2004-10-18 |
2007-08-01 |
BTG International Limited |
Use of na+/ k+-atpase inhibitors and antagonists thereof
|
|
WO2006085334A2
(en)
|
2005-02-09 |
2006-08-17 |
Dabur Pharma Limited |
Novel betulinic acid derivatives a-ring-condensed to a heterocyclic group
|
|
AU2006230429A1
(en)
|
2005-03-29 |
2006-10-05 |
Regents Of The University Of Minnesota |
Selective oxidation of triterpenes employing TEMPO
|
|
US20060252733A1
(en)
|
2005-04-07 |
2006-11-09 |
Novelix Pharmaceuticals, Inc. |
Betulin, betulin derivatives, betulinic acid and betulinic acid derivatives as novel therapeutics in the treatment of disease of lipid and/or glucose metabolism
|
|
US20090131714A1
(en)
|
2005-06-08 |
2009-05-21 |
Krasutsky Pavel A |
Synthesis of betulonic and betulinic aldehydes
|
|
JP5080249B2
(ja)
|
2005-06-10 |
2012-11-21 |
ポーラ化成工業株式会社 |
新規トリテルペン酸誘導体及びそれを含有してなる皮膚外用剤
|
|
US7402325B2
(en)
|
2005-07-28 |
2008-07-22 |
Phoenix Biotechnology, Inc. |
Supercritical carbon dioxide extract of pharmacologically active components from Nerium oleander
|
|
CN101374527A
(zh)
|
2005-12-16 |
2009-02-25 |
帕纳克斯医药公司 |
3-o-(3’,3’-二甲基琥珀酰基)桦木酸的药物盐的制备方法
|
|
EP1803461A1
(en)
|
2005-12-27 |
2007-07-04 |
Heinz-Herbert Fiebig |
Therapeutic use of an extract from the leaves of Nerium oleander
|
|
GB0604535D0
(en)
|
2006-03-07 |
2006-04-12 |
Sndv Sprl |
Betulonic acid derivatives
|
|
DE102006020582A1
(de)
*
|
2006-05-03 |
2007-11-15 |
Gesellschaft zur Förderung der Krebstherapie e.V. |
Verfahren zur Herstellung einer triterpensäurehaltigen wässrigen Lösung, triterpensäurehaltige wässrige Lösung und deren Verwendung
|
|
WO2008063318A2
(en)
|
2006-10-12 |
2008-05-29 |
The Texas A & M University System And Safe Et Al |
Betulinic acid, derivatives and analogs thereof and uses therefor
|
|
CA2668452A1
(en)
|
2006-11-03 |
2008-05-15 |
Panacos Pharmaceuticals, Inc. |
Extended triterpene derivatives
|
|
WO2008091532A1
(en)
|
2007-01-19 |
2008-07-31 |
Panacos Pharmaceuticals, Inc. |
Salts of 3-o-(3',3'-dimethylsuccinyl)betulinic acid and solid state forms thereof
|
|
US8987212B2
(en)
|
2007-08-07 |
2015-03-24 |
Muhammed Majeed |
Oleanoyl peptide composition and method of treating skin aging
|
|
CA2705272C
(en)
|
2007-11-13 |
2020-05-12 |
Phoenix Biotechnology Inc. |
Method of determining the probability of a therapeutic response in cancer chemotherapy with cardiac glycoside
|
|
ES2326065B1
(es)
|
2008-03-28 |
2010-07-08 |
Consejo Superior De Investigaciones Cientificas (Csic) |
Utilizacion de un triterpeno pentaciclico para la preparacion de una composicion farmaceutica destinada al tratamiento de la esclerosis multiple.
|
|
MX2010011439A
(es)
|
2008-04-18 |
2011-01-25 |
Reata Pharmaceuticals Inc |
Moduladores de inflamacion antioxidantes: derivados del acido oleanolico homologacion c-17.
|
|
KR101713140B1
(ko)
|
2008-04-18 |
2017-03-08 |
리타 파마슈티컬스 잉크. |
Ｃ-환에서 포화된 산화방지성 염증 조절제 올레아놀산 유도체
|
|
US8071632B2
(en)
|
2008-04-18 |
2011-12-06 |
Reata Pharmaceuticals, Inc. |
Antioxidant inflammation modulators: novel derivatives of oleanolic acid
|
|
JP5529851B2
(ja)
|
2008-04-18 |
2014-06-25 |
リアタ ファーマシューティカルズ インコーポレイテッド |
抗酸化炎症モジュレーター：ｃ−１７においてアミノ改変およびその他の改変を加えたオレアノール酸誘導体
|
|
US20110224159A1
(en)
|
2008-09-10 |
2011-09-15 |
Universite du Quebec a Chicoutime |
Bidesmosidic betulin and betulinic acid derivatives and uses thereof as antitumor agents
|
|
WO2010053817A1
(en)
|
2008-11-04 |
2010-05-14 |
Trustees Of Dartmouth College |
Betulinic acid derivatives and methods of use thereof
|
|
US8802727B2
(en)
|
2009-07-14 |
2014-08-12 |
Hetero Research Foundation, Hetero Drugs Limited |
Pharmaceutically acceptable salts of betulinic acid derivatives
|
|
TW201104501A
(en)
|
2009-07-24 |
2011-02-01 |
Asustek Comp Inc |
Device and method for inputting Chinese character
|
|
CN101704872B
(zh)
|
2009-11-23 |
2012-06-27 |
张南 |
23-羟基白桦酸衍生物、其制备方法及应用
|
|
US8685469B2
(en)
|
2009-11-30 |
2014-04-01 |
University Of Kwazulu-Natal |
In vitro anti-sickling activity of betulinic acid, oleanolic acid and their derivatives
|
|
KR101811462B1
(ko)
|
2010-01-11 |
2018-01-25 |
피닉스 바이오테크놀러지 인코포레이티드. |
협죽도 추출물을 포함하는 신경질환 치료용 조성물
|
|
US9011937B2
(en)
|
2010-11-22 |
2015-04-21 |
Phoenix Biotechnology, Inc. |
Method of treating neurological conditions with extract of Nerium species or Thevetia species
|
|
TWI386415B
(zh)
|
2010-02-02 |
2013-02-21 |
Univ Kaohsiung Medical |
熊果酸衍生物及其醫藥組合物
|
|
KR101742852B1
(ko)
*
|
2010-11-22 |
2017-06-15 |
피닉스 바이오테크놀러지 인코포레이티드. |
네리움 종 또는 테베티아 종의 추출물로 신경학적 병태를 치료하는 방법
|
|
TWI410431B
(zh)
|
2010-12-22 |
2013-10-01 |
Ind Tech Res Inst |
齊敦果酸衍生物在製備預防或治療ｃ型肝炎之藥物的用途
|
|
US20140221328A1
(en)
|
2011-01-10 |
2014-08-07 |
Bandi Parthasaradhi Reddy |
Pharmaceutically acceptable salts of novel betulinic acid derivatives
|
|
HUE026371T2
(en)
|
2011-01-31 |
2016-05-30 |
Bristol Myers Squibb Co |
C-28 amines from modified C-3 betulinic acid derivatives as anti-HIV matrices
|
|
CN102558280B
(zh)
|
2011-11-18 |
2014-09-17 |
温州大学 |
一种30-卤代桦木酸的生产方法
|
|
CN103946231B
(zh)
|
2011-12-01 |
2016-10-26 |
杭州本生药业有限公司 |
齐墩果酸酰胺化衍生物、及其制备方法和应用
|
|
JP6211527B2
(ja)
|
2011-12-01 |
2017-10-11 |
ハンジョウ ベンシェン ファーマシューティカル シーオー．， エルティーディー．Ｈａｎｇｚｈｏｕ Ｂｅｎｓｈｅｎｇ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．， Ｌｔｄ． |
２−置換オレアノール酸誘導体、その調製方法及びその用途
|
|
WO2013160810A2
(en)
|
2012-04-24 |
2013-10-31 |
Hetero Research Foundation |
Novel betulinic acid derivatives as hiv inhibitors
|
|
US8921419B2
(en)
|
2012-05-08 |
2014-12-30 |
Trustees Of Dartmouth College |
Triterpenoids and compositions containing the same
|
|
WO2014027777A2
(ko)
|
2012-08-14 |
2014-02-20 |
한국콜마 주식회사 |
신규한 우르솔릭산 유도체 및 이의 제조 방법
|
|
SMT201700501T1
(it)
|
2012-09-10 |
2017-11-15 |
Reata Pharmaceuticals Inc |
Derivati c17-eteroarilici dell'acido oleanolico e metodi d'uso degli stessi
|
|
WO2014040073A1
(en)
|
2012-09-10 |
2014-03-13 |
Reata Pharmaceuticals, Inc. |
C13-hydroxy derivatives of oleanolic acid and methods of use thereof
|
|
JP6243428B2
(ja)
|
2012-09-10 |
2017-12-06 |
リアタ ファーマシューティカルズ インコーポレイテッド |
オレアノール酸のｃ１７−アルカンジイルおよびアルケンジイル誘導体ならびにその使用方法
|
|
US9637516B2
(en)
|
2012-12-31 |
2017-05-02 |
Hetero Research Foundation |
Betulinic acid proline derivatives as HIV inhibitors
|
|
KR20150121712A
(ko)
|
2013-02-25 |
2015-10-29 |
브리스톨-마이어스 스큅 컴퍼니 |
Hiv의 치료에 유용한 c-3 알킬 및 알케닐 개질된 베툴린산 유도체
|
|
EP2813221A1
(en)
*
|
2013-06-13 |
2014-12-17 |
Natac Biotech, S.L. |
Combination of pentacyclic triterpenes and hydroxytyrosol and derivatives thereof
|
|
WO2015183794A1
(en)
*
|
2014-05-27 |
2015-12-03 |
City Of Hope |
Tgr5 agonist complexes for treating diabetes and cancer
|
|
WO2015195776A1
(en)
|
2014-06-19 |
2015-12-23 |
Bristol-Myers Squibb Company |
Betulinic acid derivatives with hiv maturation inhibitory activity
|
|
WO2018053123A1
(en)
*
|
2016-09-14 |
2018-03-22 |
Phoenix Biotechnology, Inc. |
Method and compositions for treating viral infection
|
|
MX2020002884A
(es)
*
|
2017-09-14 |
2020-10-05 |
Phoenix Biotechnology Inc |
Método y composición neuroprotectora mejorada para tratar afecciones neurológicas.
|