JP2020534284A - ワクチン、並びに、呼吸器合胞体ウイルス(rsv)感染症を予防するためのワクチンの作製方法及び使用方法 - Google Patents
ワクチン、並びに、呼吸器合胞体ウイルス(rsv)感染症を予防するためのワクチンの作製方法及び使用方法 Download PDFInfo
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- JP2020534284A JP2020534284A JP2020515680A JP2020515680A JP2020534284A JP 2020534284 A JP2020534284 A JP 2020534284A JP 2020515680 A JP2020515680 A JP 2020515680A JP 2020515680 A JP2020515680 A JP 2020515680A JP 2020534284 A JP2020534284 A JP 2020534284A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6043—Heat shock proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18571—Demonstrated in vivo effect
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20241—Use of virus, viral particle or viral elements as a vector
- C12N2760/20243—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20271—Demonstrated in vivo effect
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762559167P | 2017-09-15 | 2017-09-15 | |
| US62/559,167 | 2017-09-15 | ||
| PCT/US2018/051054 WO2019055768A1 (en) | 2017-09-15 | 2018-09-14 | VACCINES AND METHODS OF MAKING AND USING VACCINES FOR THE PREVENTION OF SYNCYTIAL RESPIRATORY VIRUS (RSV) INFECTIONS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020534284A true JP2020534284A (ja) | 2020-11-26 |
| JP2020534284A5 JP2020534284A5 (https=) | 2021-10-21 |
Family
ID=65723867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020515680A Pending JP2020534284A (ja) | 2017-09-15 | 2018-09-14 | ワクチン、並びに、呼吸器合胞体ウイルス(rsv)感染症を予防するためのワクチンの作製方法及び使用方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20200276297A1 (https=) |
| EP (1) | EP3681523A4 (https=) |
| JP (1) | JP2020534284A (https=) |
| KR (1) | KR20200096904A (https=) |
| CN (1) | CN111344008A (https=) |
| AU (1) | AU2018331467A1 (https=) |
| CA (1) | CA3075990A1 (https=) |
| WO (1) | WO2019055768A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240113662A (ko) * | 2023-01-13 | 2024-07-23 | 클립스비엔씨 주식회사 | 호흡기 신시치아 바이러스 변이체를 포함하는 호흡기 신시치아 바이러스 백신용 융합단백질 및 이의 제조방법 |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114957407A (zh) | 2019-04-02 | 2022-08-30 | 赛诺菲 | 抗原性多聚呼吸道合胞病毒多肽 |
| CN112226450B (zh) * | 2020-08-25 | 2022-10-14 | 北京交通大学 | 一种共表达呼吸道合胞病毒融合前蛋白和黏附糖蛋白的复制缺陷型腺病毒载体疫苗 |
| EP4410969A4 (en) * | 2021-09-29 | 2026-01-21 | Sk Bioscience Co Ltd | RECOMINED LIVE ATTENUATED RSV VACCINE STRAIN AND ITS PRODUCTION PROCESS |
| CN118930654A (zh) * | 2023-05-12 | 2024-11-12 | 中国科学院微生物研究所 | 一种呼吸道合胞病毒抗原制备方法和应用 |
| CN117720628A (zh) * | 2023-10-12 | 2024-03-19 | 中国科学院微生物研究所 | 一种呼吸道合胞病毒二价抗原制备方法和应用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100247621A1 (en) * | 2006-11-30 | 2010-09-30 | Government Of The Us, As Represented By The Secretary, Department Of Health And Human Services | Codon modified immunogenic compositions and methods of use |
| JP2011507514A (ja) * | 2007-12-20 | 2011-03-10 | ワイス・エルエルシー | Gタンパク質を発現する安定な細胞系を用いた、繁殖欠損水疱性口内炎ウイルスベクターをパッケージングする方法 |
| JP2017523139A (ja) * | 2014-06-13 | 2017-08-17 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 免疫原性組合せ物 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1224462A (zh) * | 1996-07-15 | 1999-07-28 | 美国政府健康及人类服务部 | 从克隆的核苷酸序列制备减毒呼吸道合胞病毒疫苗的方法 |
| IL145797A0 (en) * | 1999-04-13 | 2002-07-25 | Government Of The Us Dept Of H | Production of attenuated negative stranded rna virus vaccines from cloned nucleotide sequences |
| WO2001092548A2 (en) * | 2000-06-01 | 2001-12-06 | St. Jude Children's Research Hospital | Vaccine and gene therapy vector and methods of use thereof |
| US20050048030A1 (en) * | 2001-09-28 | 2005-03-03 | Raymond Pickles | Paramyxoviruses as gene transfer vectors to lung cells |
| CN1646684B (zh) * | 2002-02-21 | 2010-10-06 | 免疫医疗疫苗公司 | 重组副流感病毒表达系统以及包含源自间质肺病毒的异种抗原的疫苗 |
| EP1527087B2 (en) * | 2002-07-26 | 2013-07-17 | Her Majesty, The Queen in Right of Canada, as Represented by The Minister of Health | Recombinant vesicular stomatitis virus vaccines for viral hemorrhagic fevers |
| CN1871355B (zh) * | 2003-06-09 | 2011-12-14 | 惠氏 | 从cDNA中回收非节段性负链RNA病毒的改进方法 |
| ATE555208T1 (de) * | 2003-06-13 | 2012-05-15 | Apath Llc | Replikon eines negativsträngigen rna-virus |
| US8287878B2 (en) * | 2004-04-09 | 2012-10-16 | Wyeth Llc | Synergistic attenuation of vesicular stomatitis virus, vectors thereof and immunogenic compositions thereof |
| WO2009025770A2 (en) * | 2007-08-17 | 2009-02-26 | Wyeth | A heterologous prime-boost immunization regimen |
| CA2742086A1 (en) * | 2008-11-05 | 2010-05-14 | Merck Sharp & Dohme Corp. | Live, attenuated respiratory syncytial virus |
| ES2749381T3 (es) * | 2014-03-01 | 2020-03-20 | Univ Texas | Vectores víricos Isfahan recombinantes |
-
2018
- 2018-09-14 WO PCT/US2018/051054 patent/WO2019055768A1/en not_active Ceased
- 2018-09-14 EP EP18856392.8A patent/EP3681523A4/en not_active Withdrawn
- 2018-09-14 AU AU2018331467A patent/AU2018331467A1/en not_active Abandoned
- 2018-09-14 JP JP2020515680A patent/JP2020534284A/ja active Pending
- 2018-09-14 CA CA3075990A patent/CA3075990A1/en active Pending
- 2018-09-14 CN CN201880073897.7A patent/CN111344008A/zh active Pending
- 2018-09-14 US US16/647,758 patent/US20200276297A1/en not_active Abandoned
- 2018-09-14 KR KR1020207010971A patent/KR20200096904A/ko not_active Ceased
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100247621A1 (en) * | 2006-11-30 | 2010-09-30 | Government Of The Us, As Represented By The Secretary, Department Of Health And Human Services | Codon modified immunogenic compositions and methods of use |
| JP2011507514A (ja) * | 2007-12-20 | 2011-03-10 | ワイス・エルエルシー | Gタンパク質を発現する安定な細胞系を用いた、繁殖欠損水疱性口内炎ウイルスベクターをパッケージングする方法 |
| JP2017523139A (ja) * | 2014-06-13 | 2017-08-17 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 免疫原性組合せ物 |
Non-Patent Citations (3)
| Title |
|---|
| IMMUNOLOGY LETTERS, vol. 150, JPN6022030719, 2013, pages 134 - 144, ISSN: 0005012020 * |
| JOURNAL OF VIROLOGY, vol. 82, JPN6022030722, 2008, pages 12191 - 12204, ISSN: 0005012021 * |
| JOURNAL OF VIROLOGY, vol. 88, JPN6022030718, 2014, pages 5122 - 5137, ISSN: 0005012022 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240113662A (ko) * | 2023-01-13 | 2024-07-23 | 클립스비엔씨 주식회사 | 호흡기 신시치아 바이러스 변이체를 포함하는 호흡기 신시치아 바이러스 백신용 융합단백질 및 이의 제조방법 |
| KR102806300B1 (ko) | 2023-01-13 | 2025-05-14 | 클립스비엔씨 주식회사 | 호흡기 신시치아 바이러스 변이체를 포함하는 호흡기 신시치아 바이러스 백신용 융합단백질 및 이의 제조방법 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018331467A1 (en) | 2020-04-30 |
| EP3681523A4 (en) | 2021-12-29 |
| EP3681523A1 (en) | 2020-07-22 |
| KR20200096904A (ko) | 2020-08-14 |
| CA3075990A1 (en) | 2019-03-21 |
| CN111344008A (zh) | 2020-06-26 |
| US20200276297A1 (en) | 2020-09-03 |
| WO2019055768A1 (en) | 2019-03-21 |
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