JP2020532285A5 - - Google Patents
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- JP2020532285A5 JP2020532285A5 JP2020500686A JP2020500686A JP2020532285A5 JP 2020532285 A5 JP2020532285 A5 JP 2020532285A5 JP 2020500686 A JP2020500686 A JP 2020500686A JP 2020500686 A JP2020500686 A JP 2020500686A JP 2020532285 A5 JP2020532285 A5 JP 2020532285A5
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- JP
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- Prior art keywords
- seq
- amino acid
- fusion protein
- polypeptide
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023085796A JP2023120208A (ja) | 2017-07-11 | 2023-05-24 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
| JP2025044077A JP2025118590A (ja) | 2017-07-11 | 2025-03-18 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762531215P | 2017-07-11 | 2017-07-11 | |
| US62/531,215 | 2017-07-11 | ||
| PCT/US2018/041661 WO2019014360A1 (en) | 2017-07-11 | 2018-07-11 | POLYPEPTIDES BINDING COMPONENT C5 OR SERUM ALBUMIN COMPONENT AND FUSION PROTEINS THEREOF |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023085796A Division JP2023120208A (ja) | 2017-07-11 | 2023-05-24 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020532285A JP2020532285A (ja) | 2020-11-12 |
| JP2020532285A5 true JP2020532285A5 (OSRAM) | 2021-11-25 |
| JP7684803B2 JP7684803B2 (ja) | 2025-05-28 |
Family
ID=63036501
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020500686A Active JP7684803B2 (ja) | 2017-07-11 | 2018-07-11 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
| JP2023085796A Pending JP2023120208A (ja) | 2017-07-11 | 2023-05-24 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
| JP2025044077A Pending JP2025118590A (ja) | 2017-07-11 | 2025-03-18 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023085796A Pending JP2023120208A (ja) | 2017-07-11 | 2023-05-24 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
| JP2025044077A Pending JP2025118590A (ja) | 2017-07-11 | 2025-03-18 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US11498960B2 (OSRAM) |
| EP (1) | EP3625265A1 (OSRAM) |
| JP (3) | JP7684803B2 (OSRAM) |
| KR (3) | KR20250068795A (OSRAM) |
| CN (3) | CN117327187A (OSRAM) |
| AU (3) | AU2018301412B2 (OSRAM) |
| BR (1) | BR112019028269A2 (OSRAM) |
| CA (1) | CA3067247A1 (OSRAM) |
| CO (1) | CO2020000369A2 (OSRAM) |
| IL (3) | IL271920B2 (OSRAM) |
| MX (2) | MX2024005946A (OSRAM) |
| WO (1) | WO2019014360A1 (OSRAM) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20250068795A (ko) | 2017-07-11 | 2025-05-16 | 알렉시온 파마슈티칼스, 인코포레이티드 | 보체 성분 c5 또는 혈청 알부민에 결합하는 폴리펩티드 및 그의 융합 단백질 |
| WO2020092546A1 (en) * | 2018-10-30 | 2020-05-07 | Alexion Pharmaceuticals, Inc. | Co-administration of a hyaluronidase and anti-c5 antibody for treatment of complement-associated conditions |
| US20220185853A1 (en) * | 2019-04-16 | 2022-06-16 | University Of Washington | Amantadine binding protein |
| TW202434620A (zh) | 2019-07-31 | 2024-09-01 | 美商美國禮來大藥廠 | 鬆弛素(relaxin)類似物及其使用方法 |
| KR20220122608A (ko) | 2019-12-26 | 2022-09-02 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 보체 c5의 발현을 저해하는 이중 가닥 리보핵산을 함유하는 약제학적 조성물 |
| JP7343618B2 (ja) | 2020-01-17 | 2023-09-12 | オリンパス株式会社 | 発光装置、および駆動装置 |
| CN116406287A (zh) | 2020-04-16 | 2023-07-07 | 巴黎公共医疗救助机构 | 治疗由病毒引起的补体介导的障碍的方法 |
| CN116472065A (zh) * | 2020-10-05 | 2023-07-21 | 阿雷克森制药公司 | 治疗皮肌炎的方法 |
| TW202417490A (zh) * | 2022-08-31 | 2024-05-01 | 美商艾力克森製藥公司 | 用於治療鐮狀細胞病的融合多肽之劑量及投與 |
| CN116731149B (zh) * | 2023-06-07 | 2024-02-27 | 华中农业大学 | 草鱼补体活化分子碳末端肽C5a-CP及应用 |
| CN119241699B (zh) * | 2024-09-24 | 2025-11-28 | 广州康盛生物科技股份有限公司 | 一种抗人补体c5的单域抗体及其应用 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| ATE452975T1 (de) | 1992-08-21 | 2010-01-15 | Univ Bruxelles | Immunoglobuline ohne leichte ketten |
| EP0739981A1 (en) | 1995-04-25 | 1996-10-30 | Vrije Universiteit Brussel | Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes |
| DE69738166T2 (de) | 1996-06-27 | 2008-06-19 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw. | Antikörpermoleküle, die spezifisch mit dem aktiven Zentrum oder dem aktiven Spalt eines Zielmoleküls interagieren |
| EP1027439B1 (en) | 1997-10-27 | 2010-03-17 | Bac Ip B.V. | Multivalent antigen-binding proteins |
| WO2001045746A2 (en) | 1999-12-24 | 2001-06-28 | Genentech, Inc. | Methods and compositions for prolonging elimination half-times of bioactive compounds |
| DK1355919T3 (da) * | 2000-12-12 | 2011-03-14 | Medimmune Llc | Molekyler med længere halveringstider, sammensætninger og anvendelser deraf |
| JP4336771B2 (ja) | 2001-03-09 | 2009-09-30 | モルフォシス アーゲー | 血清アルブミン結合部分 |
| EP1532175B1 (en) | 2002-03-22 | 2012-10-17 | Aprogen, Inc. | Humanized antibody and process for preparing the same |
| EP1558646A2 (en) * | 2002-11-08 | 2005-08-03 | Ablynx N.V. | Single domain antibodies directed against interferon- gamma and uses thereof |
| NZ540196A (en) | 2002-11-08 | 2008-09-26 | Ablynx Nv | Camelidae antibodies against imminoglobulin E and use thereof for the treatment of allergic disorders |
| US9028816B2 (en) | 2003-01-10 | 2015-05-12 | Ablynx N.V. | Polypeptides and polypeptide constructs comprising single domain antibodies directed against von Willebrand factor |
| AU2012254935B2 (en) * | 2004-02-12 | 2014-05-29 | Archemix Llc | Aptamer Therapeutics Useful in the Treatment of Complement-Related Disorders |
| EA012622B1 (ru) * | 2004-06-01 | 2009-10-30 | Домэнтис Лимитед | Биспецифичные гибридные антитела с увеличенным периодом полувыведения из сыворотки |
| US7423128B2 (en) | 2004-11-03 | 2008-09-09 | Amgen Fremont Inc. | Anti-properdin antibodies, and methods for making and using same |
| CN100368022C (zh) | 2005-09-20 | 2008-02-13 | 中国人民解放军第二军医大学 | 双重靶向抗肝纤维化药物载体拟糖蛋白纳米粒及其制法 |
| AR056138A1 (es) * | 2005-10-21 | 2007-09-19 | Hoffmann La Roche | Procedimiento para la expresion recombinante de un polipeptido |
| KR20170002684A (ko) | 2005-11-04 | 2017-01-06 | 제넨테크, 인크. | 안질환 치료를 위한 보체 경로 억제제의 용도 |
| WO2011112850A2 (en) | 2010-03-10 | 2011-09-15 | Novelmed Therapeutics, Inc. | Humanized and chimeric anti-properdin antibodies |
| PL2262831T3 (pl) | 2008-03-03 | 2015-08-31 | Novelmed Therapeutics Inc | Przeciwciała przeciwko properdynie |
| PT2328616E (pt) | 2008-08-05 | 2015-08-26 | Novartis Ag | Composições e métodos para anticorpos dirigidos à proteína c5 do complemento |
| NZ597259A (en) | 2009-06-23 | 2014-04-30 | Alexion Pharma Inc | Bispecific antibodies that bind to complement proteins |
| CN102482701B (zh) | 2009-09-16 | 2015-05-13 | 免疫医疗公司 | I类抗-cea抗体及其使用 |
| WO2011064382A1 (en) | 2009-11-30 | 2011-06-03 | Ablynx N.V. | Improved amino acid sequences directed against human respiratory syncytial virus (hrsv) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections |
| CA2788993A1 (en) * | 2010-02-05 | 2011-08-11 | Ablynx N.V. | Peptides capable of binding to serum albumin and compounds, constructs and polypeptides comprising the same |
| TW201138808A (en) * | 2010-05-03 | 2011-11-16 | Bristol Myers Squibb Co | Serum albumin binding molecules |
| JP5827994B2 (ja) | 2010-07-09 | 2015-12-02 | アフィボディ・アーベー | ポリペプチド |
| TW201241008A (en) | 2010-10-01 | 2012-10-16 | Alexion Pharma Inc | Polypeptides that bind to human complement component C5 |
| EP2726103B1 (en) | 2011-07-01 | 2018-09-05 | The Trustees Of The University Of Pennsylvania | Anti-properdin antibodies and uses thereof |
| SG11201403416TA (en) | 2011-12-21 | 2014-07-30 | Novartis Ag | Compositions and methods for antibodies targeting factor p |
| WO2013102123A2 (en) | 2011-12-28 | 2013-07-04 | Novelmed Therapeutics, Inc. | Aglycosylated human antibody and fusion protein and uses thereof |
| JP6276202B2 (ja) | 2012-02-20 | 2018-02-07 | スウェディッシュ・オーファン・バイオヴィトラム・アーベー（ペーウーベーエル） | ヒト補体ｃ５に結合するポリペプチド |
| US9926366B2 (en) | 2012-10-04 | 2018-03-27 | Novelmed Therapeutics, Inc. | Methods of treating a hemolytic disorder comprising administering anti-properdin antibodies |
| JP7138411B2 (ja) | 2013-08-28 | 2022-09-16 | アフィボディ・アーベー | 変異した骨格を有する結合ポリペプチド |
| PT3038633T (pt) | 2013-08-28 | 2021-01-14 | Ipc Res Llc | Polipéptidos estáveis que se ligam ao complemento humano c5 |
| NZ711451A (en) * | 2014-03-07 | 2016-05-27 | Alexion Pharma Inc | Anti-c5 antibodies having improved pharmacokinetics |
| KR102613874B1 (ko) * | 2017-01-30 | 2023-12-15 | 알렉시온 파마슈티칼스, 인코포레이티드 | 1가 항-프로페르딘 항체 및 항체 단편 |
| KR20250068795A (ko) | 2017-07-11 | 2025-05-16 | 알렉시온 파마슈티칼스, 인코포레이티드 | 보체 성분 c5 또는 혈청 알부민에 결합하는 폴리펩티드 및 그의 융합 단백질 |
-
2018
- 2018-07-11 KR KR1020257014994A patent/KR20250068795A/ko active Pending
- 2018-07-11 AU AU2018301412A patent/AU2018301412B2/en active Active
- 2018-07-11 KR KR1020257021037A patent/KR20250099285A/ko active Pending
- 2018-07-11 KR KR1020207002889A patent/KR102806328B1/ko active Active
- 2018-07-11 EP EP18746529.9A patent/EP3625265A1/en active Pending
- 2018-07-11 CN CN202311281093.5A patent/CN117327187A/zh active Pending
- 2018-07-11 BR BR112019028269-6A patent/BR112019028269A2/pt unknown
- 2018-07-11 CN CN201880046102.3A patent/CN111201246B/zh active Active
- 2018-07-11 CN CN202311281139.3A patent/CN117327188A/zh active Pending
- 2018-07-11 CA CA3067247A patent/CA3067247A1/en active Pending
- 2018-07-11 JP JP2020500686A patent/JP7684803B2/ja active Active
- 2018-07-11 US US16/629,687 patent/US11498960B2/en active Active
- 2018-07-11 IL IL271920A patent/IL271920B2/en unknown
- 2018-07-11 WO PCT/US2018/041661 patent/WO2019014360A1/en not_active Ceased
-
2020
- 2020-01-08 MX MX2024005946A patent/MX2024005946A/es unknown
- 2020-01-08 MX MX2024005945A patent/MX2024005945A/es unknown
- 2020-01-15 CO CONC2020/0000369A patent/CO2020000369A2/es unknown
-
2022
- 2022-10-07 US US17/938,756 patent/US12221473B2/en active Active
-
2023
- 2023-05-24 JP JP2023085796A patent/JP2023120208A/ja active Pending
- 2023-09-21 IL IL307197A patent/IL307197B1/en unknown
-
2025
- 2025-01-02 US US19/007,782 patent/US20250163138A1/en active Pending
- 2025-01-16 AU AU2025200313A patent/AU2025200313A1/en active Pending
- 2025-01-16 AU AU2025200303A patent/AU2025200303A1/en active Pending
- 2025-03-18 JP JP2025044077A patent/JP2025118590A/ja active Pending
- 2025-10-21 IL IL324119A patent/IL324119A/en unknown
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