JP2020530446A5 - - Google Patents
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- JP2020530446A5 JP2020530446A5 JP2020505383A JP2020505383A JP2020530446A5 JP 2020530446 A5 JP2020530446 A5 JP 2020530446A5 JP 2020505383 A JP2020505383 A JP 2020505383A JP 2020505383 A JP2020505383 A JP 2020505383A JP 2020530446 A5 JP2020530446 A5 JP 2020530446A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- alkyl
- optionally substituted
- compound according
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022211691A JP2023052166A (ja) | 2017-08-09 | 2022-12-28 | 化合物、組成物、及び、方法 |
| JP2024223976A JP2025031810A (ja) | 2017-08-09 | 2024-12-19 | 化合物、組成物、及び、方法 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762543307P | 2017-08-09 | 2017-08-09 | |
| US62/543,307 | 2017-08-09 | ||
| US201762553728P | 2017-09-01 | 2017-09-01 | |
| US62/553,728 | 2017-09-01 | ||
| US201762608504P | 2017-12-20 | 2017-12-20 | |
| US62/608,504 | 2017-12-20 | ||
| PCT/US2018/045868 WO2019032743A1 (en) | 2017-08-09 | 2018-08-08 | COMPOUNDS, COMPOSITIONS AND METHODS |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022211691A Division JP2023052166A (ja) | 2017-08-09 | 2022-12-28 | 化合物、組成物、及び、方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020530446A JP2020530446A (ja) | 2020-10-22 |
| JP2020530446A5 true JP2020530446A5 (enExample) | 2021-09-16 |
Family
ID=65272557
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020505383A Withdrawn JP2020530446A (ja) | 2017-08-09 | 2018-08-08 | 化合物、組成物、及び、方法 |
| JP2022211691A Withdrawn JP2023052166A (ja) | 2017-08-09 | 2022-12-28 | 化合物、組成物、及び、方法 |
| JP2024223976A Pending JP2025031810A (ja) | 2017-08-09 | 2024-12-19 | 化合物、組成物、及び、方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022211691A Withdrawn JP2023052166A (ja) | 2017-08-09 | 2022-12-28 | 化合物、組成物、及び、方法 |
| JP2024223976A Pending JP2025031810A (ja) | 2017-08-09 | 2024-12-19 | 化合物、組成物、及び、方法 |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US11236100B2 (enExample) |
| EP (1) | EP3665156A4 (enExample) |
| JP (3) | JP2020530446A (enExample) |
| KR (2) | KR20250017299A (enExample) |
| CN (3) | CN118239938A (enExample) |
| AU (3) | AU2018313850B2 (enExample) |
| CA (1) | CA3071024A1 (enExample) |
| CL (1) | CL2020000299A1 (enExample) |
| CO (1) | CO2020001220A2 (enExample) |
| CR (1) | CR20200054A (enExample) |
| IL (2) | IL301709B2 (enExample) |
| MA (1) | MA49858A (enExample) |
| MX (2) | MX2020001352A (enExample) |
| MY (1) | MY201438A (enExample) |
| PE (1) | PE20200834A1 (enExample) |
| PH (1) | PH12020550028B1 (enExample) |
| SA (1) | SA520411222B1 (enExample) |
| SG (1) | SG11202000532SA (enExample) |
| TW (1) | TW201920115A (enExample) |
| WO (1) | WO2019032743A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110730777A (zh) * | 2017-06-07 | 2020-01-24 | 葛兰素史密斯克莱知识产权发展有限公司 | 作为atf4通路抑制剂的化学化合物 |
| IL301709B2 (en) | 2017-08-09 | 2025-07-01 | Denali Therapeutics Inc | Compounds, compositions and methods |
| TW201920129A (zh) | 2017-09-01 | 2019-06-01 | 美商戴納立製藥公司 | 化合物、組合物及方法 |
| KR20190043437A (ko) | 2017-10-18 | 2019-04-26 | 씨제이헬스케어 주식회사 | 단백질 키나제 억제제로서의 헤테로고리 화합물 |
| JP2021501785A (ja) | 2017-11-02 | 2021-01-21 | カリコ ライフ サイエンシーズ エルエルシー | 統合的ストレス経路の調節剤 |
| JP2021508336A (ja) | 2017-12-13 | 2021-03-04 | プラクシス バイオテック エルエルシー | 統合的ストレス応答経路の阻害剤 |
| US11166942B2 (en) | 2018-06-05 | 2021-11-09 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| TW202545902A (zh) | 2018-10-11 | 2025-12-01 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| KR102195348B1 (ko) | 2018-11-15 | 2020-12-24 | 에이치케이이노엔 주식회사 | 단백질 키나제 억제제로서의 신규 화합물 및 이를 포함하는 약제학적 조성물 |
| CR20210426A (es) * | 2019-02-13 | 2021-09-30 | Denali Therapeutics Inc | Compuestos, composiciones y métodos |
| EP3924341A4 (en) | 2019-02-13 | 2022-11-02 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| WO2020216766A1 (en) | 2019-04-23 | 2020-10-29 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| MX2021012904A (es) | 2019-04-23 | 2022-01-18 | Evotec Int Gmbh | Moduladores de la via de respuesta al estres integrada. |
| PH12021552759A1 (en) * | 2019-04-30 | 2022-07-04 | Abbvie Inc | Substituted cycloalkyls as modulators of the integrated stress pathway |
| JP2022536663A (ja) | 2019-06-12 | 2022-08-18 | プラクシス バイオテック エルエルシー | 統合的ストレス応答経路のモジュレーター |
| CA3162526A1 (en) | 2020-01-28 | 2021-08-05 | Christopher John Brown | Modulators of the integrated stress response pathway |
| KR20220151635A (ko) * | 2020-03-11 | 2022-11-15 | 에보텍 인터내셔널 게엠베하 | 통합 스트레스 반응 경로의 조절제 |
| MX2023004677A (es) * | 2020-10-22 | 2023-05-24 | Evotec Int Gmbh | Moduladores de la via de respuesta integrada al estres. |
| ES2997335T3 (en) | 2020-10-22 | 2025-02-17 | Evotec Int Gmbh | Modulators of the integrated stress response pathway |
| CA3195290A1 (en) | 2020-10-22 | 2022-04-28 | Holly Victoria Atton | Modulators of the integrated stress response pathway |
| CN117580824A (zh) * | 2020-10-30 | 2024-02-20 | 卡里科生命科学有限责任公司 | 整合应激通路的调节剂 |
| EP4237413A1 (en) * | 2020-10-30 | 2023-09-06 | Calico Life Sciences LLC | Modulators of the integrated stress pathway |
| CN116507608A (zh) * | 2020-11-20 | 2023-07-28 | 戴纳立制药公司 | 化合物、组合物和方法 |
| JP2023551474A (ja) * | 2020-11-25 | 2023-12-08 | エフ． ホフマン－ラ ロシュ アーゲー | Ｂ型肝炎ウイルス感染症の処置および予防のための芳香族架橋環アミド誘導体 |
| TW202241857A (zh) | 2020-12-18 | 2022-11-01 | 美商戴納立製藥公司 | 化合物之固體形式 |
| JP2025523444A (ja) * | 2022-06-23 | 2025-07-23 | デナリ セラピューティクス インコーポレイテッド | 真核生物型開始因子２ｂのモジュレーターの調製プロセス |
| AU2023384649A1 (en) | 2022-11-21 | 2025-05-22 | Shenzhen Zhongge Biological Technology Co., Ltd. | Compound, pharmaceutical composition containing same, synthesis method therefor and use thereof |
| WO2025019827A1 (en) * | 2023-07-20 | 2025-01-23 | Denali Therapeutics Inc. | Formulation, solid dosage form, and methods |
| WO2025230528A1 (en) * | 2024-05-01 | 2025-11-06 | Calico Life Sciences Llc | Methods of treating amyotrophic lateral sclerosis |
| WO2026004939A1 (ja) * | 2024-06-28 | 2026-01-02 | キッセイ薬品工業株式会社 | ジ置換ビシクロ［１．１．１］ペンタン化合物 |
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| TW201920129A (zh) | 2017-09-01 | 2019-06-01 | 美商戴納立製藥公司 | 化合物、組合物及方法 |
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| JP2021501785A (ja) | 2017-11-02 | 2021-01-21 | カリコ ライフ サイエンシーズ エルエルシー | 統合的ストレス経路の調節剤 |
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| JP2021529814A (ja) | 2018-07-09 | 2021-11-04 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ | 化学化合物 |
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| TW202545902A (zh) | 2018-10-11 | 2025-12-01 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| EP3924341A4 (en) | 2019-02-13 | 2022-11-02 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| CR20210426A (es) | 2019-02-13 | 2021-09-30 | Denali Therapeutics Inc | Compuestos, composiciones y métodos |
| US20220177456A1 (en) | 2019-03-06 | 2022-06-09 | Denali Therapeutics Inc. | Compounds, compositions and methods |
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| PH12021552759A1 (en) | 2019-04-30 | 2022-07-04 | Abbvie Inc | Substituted cycloalkyls as modulators of the integrated stress pathway |
| TW202241857A (zh) | 2020-12-18 | 2022-11-01 | 美商戴納立製藥公司 | 化合物之固體形式 |
-
2018
- 2018-08-08 IL IL301709A patent/IL301709B2/en unknown
- 2018-08-08 IL IL272089A patent/IL272089B2/en unknown
- 2018-08-08 PE PE2020000174A patent/PE20200834A1/es unknown
- 2018-08-08 MA MA049858A patent/MA49858A/fr unknown
- 2018-08-08 PH PH1/2020/550028A patent/PH12020550028B1/en unknown
- 2018-08-08 CA CA3071024A patent/CA3071024A1/en active Pending
- 2018-08-08 CN CN202410187269.9A patent/CN118239938A/zh active Pending
- 2018-08-08 CN CN201880055607.6A patent/CN111094233B/zh active Active
- 2018-08-08 CN CN202410183135.XA patent/CN118239937A/zh active Pending
- 2018-08-08 KR KR1020257001611A patent/KR20250017299A/ko active Pending
- 2018-08-08 CR CR20200054A patent/CR20200054A/es unknown
- 2018-08-08 AU AU2018313850A patent/AU2018313850B2/en active Active
- 2018-08-08 MX MX2020001352A patent/MX2020001352A/es unknown
- 2018-08-08 US US16/637,718 patent/US11236100B2/en active Active
- 2018-08-08 KR KR1020207005952A patent/KR102757890B1/ko active Active
- 2018-08-08 JP JP2020505383A patent/JP2020530446A/ja not_active Withdrawn
- 2018-08-08 EP EP18844666.0A patent/EP3665156A4/en active Pending
- 2018-08-08 WO PCT/US2018/045868 patent/WO2019032743A1/en not_active Ceased
- 2018-08-08 MY MYPI2020000561A patent/MY201438A/en unknown
- 2018-08-08 SG SG11202000532SA patent/SG11202000532SA/en unknown
- 2018-08-09 TW TW107127864A patent/TW201920115A/zh unknown
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2020
- 2020-01-31 MX MX2023003989A patent/MX2023003989A/es unknown
- 2020-02-02 SA SA520411222A patent/SA520411222B1/ar unknown
- 2020-02-03 CO CONC2020/0001220A patent/CO2020001220A2/es unknown
- 2020-02-03 CL CL2020000299A patent/CL2020000299A1/es unknown
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2021
- 2021-11-19 US US17/531,039 patent/US11851440B2/en active Active
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2022
- 2022-12-28 JP JP2022211691A patent/JP2023052166A/ja not_active Withdrawn
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2023
- 2023-03-22 AU AU2023201775A patent/AU2023201775A1/en not_active Abandoned
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2024
- 2024-12-19 JP JP2024223976A patent/JP2025031810A/ja active Pending
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2025
- 2025-01-08 US US19/014,044 patent/US20250388595A1/en active Pending
- 2025-01-31 AU AU2025200658A patent/AU2025200658A1/en active Pending
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