JP2020511459A5 - - Google Patents

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JP2020511459A5
JP2020511459A5 JP2019550175A JP2019550175A JP2020511459A5 JP 2020511459 A5 JP2020511459 A5 JP 2020511459A5 JP 2019550175 A JP2019550175 A JP 2019550175A JP 2019550175 A JP2019550175 A JP 2019550175A JP 2020511459 A5 JP2020511459 A5 JP 2020511459A5
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peptide
active agent
item
items
seq
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JP2019550175A
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Japanese (ja)
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JP2020511459A (ja
JP7280193B2 (ja
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Priority claimed from PCT/US2018/023006 external-priority patent/WO2018170480A1/en
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Priority to JP2023078678A priority Critical patent/JP2023099623A/ja
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JP2019550175A 2017-03-16 2018-03-16 軟骨ホーミングペプチドコンジュゲート及びその使用方法 Active JP7280193B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023078678A JP2023099623A (ja) 2017-03-16 2023-05-11 軟骨ホーミングペプチドコンジュゲート及びその使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762472485P 2017-03-16 2017-03-16
US62/472,485 2017-03-16
PCT/US2018/023006 WO2018170480A1 (en) 2017-03-16 2018-03-16 Cartilage-homing peptide conjugates and methods of use thereof

Related Child Applications (1)

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JP2023078678A Division JP2023099623A (ja) 2017-03-16 2023-05-11 軟骨ホーミングペプチドコンジュゲート及びその使用方法

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JP2020511459A JP2020511459A (ja) 2020-04-16
JP2020511459A5 true JP2020511459A5 (https=) 2021-04-15
JP7280193B2 JP7280193B2 (ja) 2023-05-23

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JP2019550175A Active JP7280193B2 (ja) 2017-03-16 2018-03-16 軟骨ホーミングペプチドコンジュゲート及びその使用方法
JP2023078678A Pending JP2023099623A (ja) 2017-03-16 2023-05-11 軟骨ホーミングペプチドコンジュゲート及びその使用方法

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US (2) US11013814B2 (https=)
EP (1) EP3595699A4 (https=)
JP (2) JP7280193B2 (https=)
CN (1) CN110475565A (https=)
AU (1) AU2018236465A1 (https=)
CA (1) CA3056421A1 (https=)
WO (1) WO2018170480A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11559580B1 (en) 2013-09-17 2023-01-24 Blaze Bioscience, Inc. Tissue-homing peptide conjugates and methods of use thereof
US11090358B2 (en) 2015-09-09 2021-08-17 Fred Hutchinson Cancer Research Center Cartilage-homing peptides
AU2018210157B2 (en) 2017-01-18 2022-10-06 Fred Hutchinson Cancer Center Peptide compositions and methods of use thereof for disrupting TEAD interactions
EP3595699A4 (en) 2017-03-16 2020-12-23 Blaze Bioscience, Inc. PEPTIDIC CONJUGATES OF CARTILAGE ECOTROPISM AND THEIR METHODS OF USE
AU2018283161A1 (en) 2017-06-15 2020-01-02 Blaze Bioscience, Inc. Renal-homing peptide conjugates and methods of use thereof
EP3727146A4 (en) 2017-12-19 2021-10-06 Blaze Bioscience, Inc. TUMOR HOMING AND CELL-PENETANT PEPTIDE IMMUNO-ONCOLOGY AGENT COMPLEX AND METHOD OF USE
WO2019178573A1 (en) * 2018-03-16 2019-09-19 Blaze Bioscience, Inc. Truncated cartilage-homing peptides and peptide complexes and methods of use thereof
WO2019209662A1 (en) * 2018-04-23 2019-10-31 Fred Hutchinson Cancer Research Center Conjugates of cartilage-homing peptides
US20200171051A1 (en) * 2018-11-30 2020-06-04 Renibus Therapeutics, Inc. Methods for treating renal injury by therapeutically upregulating p21
WO2020150679A1 (en) * 2019-01-18 2020-07-23 Memorial Sloan Kettering Cancer Center Proteins and fluorophore containing compounds selective for navl7
US12383547B2 (en) 2020-07-01 2025-08-12 Vanderbilt University Methods of treatment for a kidney disease
JP2024503480A (ja) * 2021-01-19 2024-01-25 ウィリアム マーシュ ライス ユニバーシティ ポリペプチドの骨特異的送達法
CN113577246B (zh) * 2021-08-02 2023-11-03 赛克赛斯生物科技股份有限公司 一种预防瘢痕粘连的组合物、术后防粘连材料及应用
WO2024173795A1 (en) * 2023-02-17 2024-08-22 California Institute Of Technology Activatable drug conjugates and therapeutic applications thereof
CN120459270A (zh) * 2025-05-16 2025-08-12 中国人民解放军海军军医大学 OpiCa1或其纳米脂质体在制备治疗和/或预防心肌纤维化相关疾病药物中的应用

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998016254A1 (en) 1996-10-17 1998-04-23 Immunomedics, Inc. Non-antigenic toxin-conjugate and fusion protein of internalizing receptor system
AU2001229494A1 (en) 2000-01-21 2001-07-31 The Burnham Institute Chimeric prostate-homing peptides with pro-apoptotic activity
WO2003020751A2 (en) 2001-09-05 2003-03-13 King's College London Homing peptides
CN1655675A (zh) 2002-03-26 2005-08-17 综合医院公司 利用三叶肽的联合治疗
US20060088899A1 (en) 2002-05-31 2006-04-27 Alvarez Vernon L Combination chemotherapy with chlorotoxin
UA91325C2 (ru) * 2002-12-26 2010-07-26 Маунтин Вью Фармасьютикалз, Инк. Полимерные конъюгаты цитокинов, хемокинов, факторов роста, полипептидных гормонов и их антагонистов с сохраненной активностью рецепторного связывания
CA2582552A1 (en) * 2004-10-21 2006-05-04 Igf Oncology, Llc Toxins and radionuclides coupled to igf-1 receptor ligands for treatment of cancer
FR2877946B1 (fr) 2004-11-12 2011-02-11 Commissariat Energie Atomique Peptides derives de la maurocalcine utilisables comme vecteurs pour l'adressage intracellulaire de molecules d'interet
CN101583370A (zh) 2005-09-27 2009-11-18 阿穆尼克斯公司 蛋白质药物及其用途
US7592009B2 (en) 2006-10-10 2009-09-22 Ecole Polytechnique Federale De Lausanne (Epfl) Polypeptide ligands for targeting cartilage and methods of use thereof
JP5463013B2 (ja) 2007-06-19 2014-04-09 国立大学法人 岡山大学 軟骨マーカー
EP2211913A4 (en) 2007-10-12 2010-12-22 Transmolecular Inc SYSTEMIC ADMINISTRATION OF CHLOROTOXIN AGENTS FOR THE DIAGNOSIS AND TREATMENT OF TUMORS
JP5858932B2 (ja) 2010-02-04 2016-02-10 モルフォテック, インコーポレイテッド クロロトキシンポリペプチドおよびコンジュゲートならびにその使用
JP2013532126A (ja) 2010-05-11 2013-08-15 フレッド ハッチンソン キャンサー リサーチ センター クロロトキシン変異体、コンジュゲート、およびそれらを使用する方法
US20130280281A1 (en) 2010-07-02 2013-10-24 Jean-Paul Castaigne Short and d-amino acid-containing polypeptides for therapeutic conjugates and uses thereof
EP2638173B1 (en) 2010-11-08 2019-06-19 The Board of Trustees of The Leland Stanford Junior University Fusion proteins comprising an engineered knottin peptide and uses thereof
WO2013078250A2 (en) 2011-11-22 2013-05-30 The Board Of Trustees Of The Leland Stanford Junior University Cystine knot peptides that bind alpha-v-beta-6 integrin
WO2013078091A1 (en) 2011-11-22 2013-05-30 The Johns Hopkins University Collagen mimetic peptides for targeting collagen strands for in vitro and in vivo imaging and therapeutic use
JP5724937B2 (ja) 2012-04-23 2015-05-27 ニプロ株式会社 腎臓集積性を示すペプチド、製剤
US8945553B2 (en) * 2012-05-22 2015-02-03 Bristol-Myers Squibb Company Bispecific antibodies to IL-23 and IL-17A/F
EP2864360B1 (en) * 2012-06-25 2017-09-06 The Brigham and Women's Hospital, Inc. Targeted therapeutics
WO2014063012A1 (en) 2012-10-19 2014-04-24 The Board Of Trustees Of The Leland Stanford Junior University Conjugated knottin mini-proteins containing non-natural amino acids
CN105008393A (zh) * 2012-12-10 2015-10-28 弗莱德哈钦森癌症研究中心 用于筛选的方法
WO2014180534A1 (de) 2013-05-07 2014-11-13 Merck Patent Gmbh Peptide und peptid-wirkstoff-konjugate für renales targeting
JP2016528174A (ja) * 2013-05-31 2016-09-15 セルリアン・ファーマ・インコーポレイテッド 治療的送達用のシクロデキストリンベースのポリマー
EP3024472A4 (en) 2013-07-22 2017-06-28 Kineta One, LLC Ophthalmic uses of toxin-based therapeutic peptides and pharmaceutical compositions thereof
US20170050988A1 (en) 2013-11-25 2017-02-23 Sanofi Dotam derivatives for therapeutic use
US20160338967A1 (en) * 2013-12-23 2016-11-24 Kineta One, Llc Sustained release depot formulations of therapeutic proteins, and uses thereof
CN114805527A (zh) 2014-05-21 2022-07-29 哈佛大学的校长及成员们 Ras抑制肽和其用途
CN107405388A (zh) 2015-01-08 2017-11-28 衣阿华大学研究基金会 用于体内关节软骨再生的方法
WO2016112208A2 (en) 2015-01-09 2016-07-14 Kineta One, Llp Topical applications of kv1.3 channel blocking peptides to treat skin inflammation
WO2016118859A1 (en) 2015-01-22 2016-07-28 Board Of Trustees Of The University Of Arkansas Compositions and methods for selectively depleting senescent cells comprising flip
WO2016210376A2 (en) 2015-06-26 2016-12-29 Fred Hutchinson Cancer Research Center Therapeutic peptides and methods of use thereof
CN112574316A (zh) 2015-07-02 2021-03-30 博际生物医药科技(杭州)有限公司 用于肿瘤靶向治疗的白细胞介素-15融合蛋白
US11090358B2 (en) 2015-09-09 2021-08-17 Fred Hutchinson Cancer Research Center Cartilage-homing peptides
AU2016366668A1 (en) * 2015-12-11 2018-05-31 Fred Hutchinson Cancer Research Center Peptides for renal therapy
WO2017143259A1 (en) 2016-02-19 2017-08-24 Dignity Health Antibody fusion protein and related compositions for targeting cancer
US20190375786A1 (en) * 2016-09-09 2019-12-12 Fred Hutchinson Cancer Research Center Stable peptides and methods of use thereof
WO2018119001A1 (en) 2016-12-19 2018-06-28 Fred Hutchinson Cancer Research Center Peptide-antibody compositions and methods of use thereof
AU2018210157B2 (en) 2017-01-18 2022-10-06 Fred Hutchinson Cancer Center Peptide compositions and methods of use thereof for disrupting TEAD interactions
EP3595699A4 (en) 2017-03-16 2020-12-23 Blaze Bioscience, Inc. PEPTIDIC CONJUGATES OF CARTILAGE ECOTROPISM AND THEIR METHODS OF USE
AU2018283161A1 (en) 2017-06-15 2020-01-02 Blaze Bioscience, Inc. Renal-homing peptide conjugates and methods of use thereof

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