JP2018527348A5 - - Google Patents
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- JP2018527348A5 JP2018527348A5 JP2018510741A JP2018510741A JP2018527348A5 JP 2018527348 A5 JP2018527348 A5 JP 2018527348A5 JP 2018510741 A JP2018510741 A JP 2018510741A JP 2018510741 A JP2018510741 A JP 2018510741A JP 2018527348 A5 JP2018527348 A5 JP 2018527348A5
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- Japan
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021172263A JP7378449B2 (ja) | 2015-09-09 | 2021-10-21 | 軟骨ホーミングペプチド |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562216331P | 2015-09-09 | 2015-09-09 | |
| US62/216,331 | 2015-09-09 | ||
| US201662278929P | 2016-01-14 | 2016-01-14 | |
| US62/278,929 | 2016-01-14 | ||
| US201662385734P | 2016-09-09 | 2016-09-09 | |
| US62/385,734 | 2016-09-09 | ||
| PCT/US2016/051166 WO2017044894A2 (en) | 2015-09-09 | 2016-09-09 | Cartilage-homing peptides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021172263A Division JP7378449B2 (ja) | 2015-09-09 | 2021-10-21 | 軟骨ホーミングペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018527348A JP2018527348A (ja) | 2018-09-20 |
| JP2018527348A5 true JP2018527348A5 (https=) | 2019-10-10 |
| JP6966424B2 JP6966424B2 (ja) | 2021-11-17 |
Family
ID=58240183
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018510741A Expired - Fee Related JP6966424B2 (ja) | 2015-09-09 | 2016-09-09 | 軟骨ホーミングペプチド |
| JP2021172263A Active JP7378449B2 (ja) | 2015-09-09 | 2021-10-21 | 軟骨ホーミングペプチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021172263A Active JP7378449B2 (ja) | 2015-09-09 | 2021-10-21 | 軟骨ホーミングペプチド |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US11090358B2 (https=) |
| EP (1) | EP3347035A4 (https=) |
| JP (2) | JP6966424B2 (https=) |
| CN (1) | CN108135970B (https=) |
| AU (1) | AU2016321342A1 (https=) |
| BR (1) | BR112018004536A2 (https=) |
| CA (1) | CA2994865A1 (https=) |
| IL (1) | IL257396B (https=) |
| WO (1) | WO2017044894A2 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2890501T3 (es) | 2009-03-02 | 2022-01-20 | Massachusetts Inst Technology | Métodos y productos para la creación de perfiles enzimáticos in vivo |
| CA2830235C (en) | 2011-03-15 | 2023-10-24 | Massachusetts Institute Of Technology | Multiplexed detection with isotope-coded reporters |
| JP6847660B2 (ja) | 2013-06-07 | 2021-03-24 | マサチューセッツ インスティテュート オブ テクノロジー | リガンドをコードする合成バイオマーカーのアフィニティベースの検出 |
| US11559580B1 (en) | 2013-09-17 | 2023-01-24 | Blaze Bioscience, Inc. | Tissue-homing peptide conjugates and methods of use thereof |
| US11090358B2 (en) | 2015-09-09 | 2021-08-17 | Fred Hutchinson Cancer Research Center | Cartilage-homing peptides |
| WO2017177115A1 (en) | 2016-04-08 | 2017-10-12 | Massachusetts Institute Of Technology | Methods to specifically profile protease activity at lymph nodes |
| US11428689B2 (en) | 2016-05-05 | 2022-08-30 | Massachusetts Institute Of Technology | Methods and uses for remotely triggered protease activity measurements |
| US20190375786A1 (en) | 2016-09-09 | 2019-12-12 | Fred Hutchinson Cancer Research Center | Stable peptides and methods of use thereof |
| AU2018210157B2 (en) | 2017-01-18 | 2022-10-06 | Fred Hutchinson Cancer Center | Peptide compositions and methods of use thereof for disrupting TEAD interactions |
| EP3595699A4 (en) * | 2017-03-16 | 2020-12-23 | Blaze Bioscience, Inc. | PEPTIDIC CONJUGATES OF CARTILAGE ECOTROPISM AND THEIR METHODS OF USE |
| CA3059358A1 (en) | 2017-04-07 | 2018-10-11 | Massachusetts Institute Of Technology | Methods to spatially profile protease activity in tissue and sections |
| AU2018283161A1 (en) | 2017-06-15 | 2020-01-02 | Blaze Bioscience, Inc. | Renal-homing peptide conjugates and methods of use thereof |
| IT201700071296A1 (it) * | 2017-06-26 | 2018-12-26 | Alda S R L | Nuovi reagenti per microscopia ottica |
| EP3727146A4 (en) * | 2017-12-19 | 2021-10-06 | Blaze Bioscience, Inc. | TUMOR HOMING AND CELL-PENETANT PEPTIDE IMMUNO-ONCOLOGY AGENT COMPLEX AND METHOD OF USE |
| WO2019178573A1 (en) * | 2018-03-16 | 2019-09-19 | Blaze Bioscience, Inc. | Truncated cartilage-homing peptides and peptide complexes and methods of use thereof |
| WO2019209662A1 (en) * | 2018-04-23 | 2019-10-31 | Fred Hutchinson Cancer Research Center | Conjugates of cartilage-homing peptides |
| EP3856921B1 (en) | 2018-09-25 | 2026-04-29 | Massachusetts Institute Of Technology | Lung protease nanosensors and uses thereof |
| WO2020150560A1 (en) | 2019-01-17 | 2020-07-23 | Massachusetts Institute Of Technology | Sensors for detecting and imaging of cancer metastasis |
| CN110357950B (zh) * | 2019-07-29 | 2023-04-25 | 武汉大学 | 酸性氨基酸扫描法设计的免疫抑制多肽及应用 |
| CN111454334B (zh) * | 2020-03-30 | 2021-12-14 | 东北农业大学 | 一种抗酶解的抗菌肽ii4ii及制备方法和应用 |
| CN111840512B (zh) * | 2020-07-15 | 2023-06-09 | 广州领晟医疗科技有限公司 | 治疗软骨修复和/或骨关节炎的组合物 |
| CN113332442A (zh) * | 2021-06-10 | 2021-09-03 | 愈美明德(成都)生物医药科技有限公司 | 一种靶向递送分子、粒子及其制备方法、应用 |
| CN118091163B (zh) * | 2024-04-26 | 2024-07-02 | 山东省食品药品检验研究院 | 一种鉴别尖刺信使蝎的特征多肽及其应用 |
| CN120865334A (zh) * | 2025-03-26 | 2025-10-31 | 中山大学附属第五医院 | 一种靶向软骨的阳离子肽类化合物及其制备方法与应用 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998016254A1 (en) | 1996-10-17 | 1998-04-23 | Immunomedics, Inc. | Non-antigenic toxin-conjugate and fusion protein of internalizing receptor system |
| AU2001229494A1 (en) | 2000-01-21 | 2001-07-31 | The Burnham Institute | Chimeric prostate-homing peptides with pro-apoptotic activity |
| WO2003020751A2 (en) | 2001-09-05 | 2003-03-13 | King's College London | Homing peptides |
| CN1655675A (zh) | 2002-03-26 | 2005-08-17 | 综合医院公司 | 利用三叶肽的联合治疗 |
| US20060088899A1 (en) | 2002-05-31 | 2006-04-27 | Alvarez Vernon L | Combination chemotherapy with chlorotoxin |
| FR2877946B1 (fr) | 2004-11-12 | 2011-02-11 | Commissariat Energie Atomique | Peptides derives de la maurocalcine utilisables comme vecteurs pour l'adressage intracellulaire de molecules d'interet |
| CN101583370A (zh) | 2005-09-27 | 2009-11-18 | 阿穆尼克斯公司 | 蛋白质药物及其用途 |
| US7592009B2 (en) | 2006-10-10 | 2009-09-22 | Ecole Polytechnique Federale De Lausanne (Epfl) | Polypeptide ligands for targeting cartilage and methods of use thereof |
| JP5463013B2 (ja) * | 2007-06-19 | 2014-04-09 | 国立大学法人 岡山大学 | 軟骨マーカー |
| EP2211913A4 (en) | 2007-10-12 | 2010-12-22 | Transmolecular Inc | SYSTEMIC ADMINISTRATION OF CHLOROTOXIN AGENTS FOR THE DIAGNOSIS AND TREATMENT OF TUMORS |
| JP5858932B2 (ja) | 2010-02-04 | 2016-02-10 | モルフォテック， インコーポレイテッド | クロロトキシンポリペプチドおよびコンジュゲートならびにその使用 |
| JP2013532126A (ja) | 2010-05-11 | 2013-08-15 | フレッド ハッチンソン キャンサー リサーチ センター | クロロトキシン変異体、コンジュゲート、およびそれらを使用する方法 |
| US20130280281A1 (en) | 2010-07-02 | 2013-10-24 | Jean-Paul Castaigne | Short and d-amino acid-containing polypeptides for therapeutic conjugates and uses thereof |
| EP2638173B1 (en) | 2010-11-08 | 2019-06-19 | The Board of Trustees of The Leland Stanford Junior University | Fusion proteins comprising an engineered knottin peptide and uses thereof |
| WO2013078091A1 (en) | 2011-11-22 | 2013-05-30 | The Johns Hopkins University | Collagen mimetic peptides for targeting collagen strands for in vitro and in vivo imaging and therapeutic use |
| WO2013078250A2 (en) | 2011-11-22 | 2013-05-30 | The Board Of Trustees Of The Leland Stanford Junior University | Cystine knot peptides that bind alpha-v-beta-6 integrin |
| JP5724937B2 (ja) | 2012-04-23 | 2015-05-27 | ニプロ株式会社 | 腎臓集積性を示すペプチド、製剤 |
| US8945553B2 (en) | 2012-05-22 | 2015-02-03 | Bristol-Myers Squibb Company | Bispecific antibodies to IL-23 and IL-17A/F |
| EP2864360B1 (en) | 2012-06-25 | 2017-09-06 | The Brigham and Women's Hospital, Inc. | Targeted therapeutics |
| WO2014063012A1 (en) | 2012-10-19 | 2014-04-24 | The Board Of Trustees Of The Leland Stanford Junior University | Conjugated knottin mini-proteins containing non-natural amino acids |
| CN105008393A (zh) * | 2012-12-10 | 2015-10-28 | 弗莱德哈钦森癌症研究中心 | 用于筛选的方法 |
| EP2981821B2 (en) | 2013-04-02 | 2021-11-03 | Merck Sharp & Dohme Corp. | Immunohistochemical assay for detecting expression of programmed death ligand 1 (pd-l1) in tumor tissue |
| WO2014180534A1 (de) | 2013-05-07 | 2014-11-13 | Merck Patent Gmbh | Peptide und peptid-wirkstoff-konjugate für renales targeting |
| EP3024472A4 (en) * | 2013-07-22 | 2017-06-28 | Kineta One, LLC | Ophthalmic uses of toxin-based therapeutic peptides and pharmaceutical compositions thereof |
| US20170050988A1 (en) * | 2013-11-25 | 2017-02-23 | Sanofi | Dotam derivatives for therapeutic use |
| US20160338967A1 (en) | 2013-12-23 | 2016-11-24 | Kineta One, Llc | Sustained release depot formulations of therapeutic proteins, and uses thereof |
| CN114805527A (zh) | 2014-05-21 | 2022-07-29 | 哈佛大学的校长及成员们 | Ras抑制肽和其用途 |
| CN107405388A (zh) | 2015-01-08 | 2017-11-28 | 衣阿华大学研究基金会 | 用于体内关节软骨再生的方法 |
| WO2016112208A2 (en) | 2015-01-09 | 2016-07-14 | Kineta One, Llp | Topical applications of kv1.3 channel blocking peptides to treat skin inflammation |
| WO2016118859A1 (en) | 2015-01-22 | 2016-07-28 | Board Of Trustees Of The University Of Arkansas | Compositions and methods for selectively depleting senescent cells comprising flip |
| WO2016210376A2 (en) * | 2015-06-26 | 2016-12-29 | Fred Hutchinson Cancer Research Center | Therapeutic peptides and methods of use thereof |
| CN112574316A (zh) | 2015-07-02 | 2021-03-30 | 博际生物医药科技(杭州)有限公司 | 用于肿瘤靶向治疗的白细胞介素-15融合蛋白 |
| US11090358B2 (en) | 2015-09-09 | 2021-08-17 | Fred Hutchinson Cancer Research Center | Cartilage-homing peptides |
| AU2016366668A1 (en) | 2015-12-11 | 2018-05-31 | Fred Hutchinson Cancer Research Center | Peptides for renal therapy |
| WO2017143259A1 (en) | 2016-02-19 | 2017-08-24 | Dignity Health | Antibody fusion protein and related compositions for targeting cancer |
| US20190375786A1 (en) | 2016-09-09 | 2019-12-12 | Fred Hutchinson Cancer Research Center | Stable peptides and methods of use thereof |
| WO2018119001A1 (en) | 2016-12-19 | 2018-06-28 | Fred Hutchinson Cancer Research Center | Peptide-antibody compositions and methods of use thereof |
| AU2018210157B2 (en) | 2017-01-18 | 2022-10-06 | Fred Hutchinson Cancer Center | Peptide compositions and methods of use thereof for disrupting TEAD interactions |
| EP3595699A4 (en) | 2017-03-16 | 2020-12-23 | Blaze Bioscience, Inc. | PEPTIDIC CONJUGATES OF CARTILAGE ECOTROPISM AND THEIR METHODS OF USE |
| AU2018283161A1 (en) | 2017-06-15 | 2020-01-02 | Blaze Bioscience, Inc. | Renal-homing peptide conjugates and methods of use thereof |
-
2016
- 2016-09-09 US US15/758,320 patent/US11090358B2/en active Active
- 2016-09-09 JP JP2018510741A patent/JP6966424B2/ja not_active Expired - Fee Related
- 2016-09-09 CA CA2994865A patent/CA2994865A1/en not_active Abandoned
- 2016-09-09 AU AU2016321342A patent/AU2016321342A1/en not_active Abandoned
- 2016-09-09 CN CN201680053482.4A patent/CN108135970B/zh not_active Expired - Fee Related
- 2016-09-09 BR BR112018004536A patent/BR112018004536A2/pt not_active IP Right Cessation
- 2016-09-09 WO PCT/US2016/051166 patent/WO2017044894A2/en not_active Ceased
- 2016-09-09 EP EP16845226.6A patent/EP3347035A4/en not_active Withdrawn
-
2018
- 2018-02-07 IL IL257396A patent/IL257396B/en active IP Right Grant
-
2021
- 2021-06-21 US US17/353,447 patent/US11648290B2/en active Active
- 2021-10-21 JP JP2021172263A patent/JP7378449B2/ja active Active
-
2023
- 2023-03-02 US US18/177,642 patent/US20230364183A1/en not_active Abandoned
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