JP2018527348A5 - - Google Patents
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- JP2018527348A5 JP2018527348A5 JP2018510741A JP2018510741A JP2018527348A5 JP 2018527348 A5 JP2018527348 A5 JP 2018527348A5 JP 2018510741 A JP2018510741 A JP 2018510741A JP 2018510741 A JP2018510741 A JP 2018510741A JP 2018527348 A5 JP2018527348 A5 JP 2018527348A5
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- JP
- Japan
- Prior art keywords
- seq
- composition
- agent
- item
- peptide
- Prior art date
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021172263A JP7378449B2 (ja) | 2015-09-09 | 2021-10-21 | 軟骨ホーミングペプチド |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562216331P | 2015-09-09 | 2015-09-09 | |
| US62/216,331 | 2015-09-09 | ||
| US201662278929P | 2016-01-14 | 2016-01-14 | |
| US62/278,929 | 2016-01-14 | ||
| US201662385734P | 2016-09-09 | 2016-09-09 | |
| PCT/US2016/051166 WO2017044894A2 (en) | 2015-09-09 | 2016-09-09 | Cartilage-homing peptides |
| US62/385,734 | 2016-09-09 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021172263A Division JP7378449B2 (ja) | 2015-09-09 | 2021-10-21 | 軟骨ホーミングペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018527348A JP2018527348A (ja) | 2018-09-20 |
| JP2018527348A5 true JP2018527348A5 (https=) | 2019-10-10 |
| JP6966424B2 JP6966424B2 (ja) | 2021-11-17 |
Family
ID=58240183
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018510741A Expired - Fee Related JP6966424B2 (ja) | 2015-09-09 | 2016-09-09 | 軟骨ホーミングペプチド |
| JP2021172263A Active JP7378449B2 (ja) | 2015-09-09 | 2021-10-21 | 軟骨ホーミングペプチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021172263A Active JP7378449B2 (ja) | 2015-09-09 | 2021-10-21 | 軟骨ホーミングペプチド |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US11090358B2 (https=) |
| EP (1) | EP3347035A4 (https=) |
| JP (2) | JP6966424B2 (https=) |
| CN (1) | CN108135970B (https=) |
| AU (1) | AU2016321342A1 (https=) |
| BR (1) | BR112018004536A2 (https=) |
| CA (1) | CA2994865A1 (https=) |
| IL (1) | IL257396B (https=) |
| WO (1) | WO2017044894A2 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8673267B2 (en) | 2009-03-02 | 2014-03-18 | Massachusetts Institute Of Technology | Methods and products for in vivo enzyme profiling |
| JP6245990B2 (ja) | 2011-03-15 | 2017-12-13 | マサチューセッツ インスティテュート オブ テクノロジー | 同位体によりコード化されたレポーターによる多重検出 |
| JP6847660B2 (ja) | 2013-06-07 | 2021-03-24 | マサチューセッツ インスティテュート オブ テクノロジー | リガンドをコードする合成バイオマーカーのアフィニティベースの検出 |
| US11559580B1 (en) | 2013-09-17 | 2023-01-24 | Blaze Bioscience, Inc. | Tissue-homing peptide conjugates and methods of use thereof |
| WO2017044894A2 (en) | 2015-09-09 | 2017-03-16 | Fred Hutchinson Cancer Research Center | Cartilage-homing peptides |
| EP3440013A4 (en) | 2016-04-08 | 2021-03-17 | Massachusetts Institute of Technology | METHOD FOR SPECIFIC PROFILING OF PROTEASE ACTIVITY ON LYMPH NODES |
| WO2017193070A1 (en) | 2016-05-05 | 2017-11-09 | Massachusetts Institute Of Technology | Methods and uses for remotely triggered protease activity measurements |
| CA3033004A1 (en) | 2016-09-09 | 2018-03-15 | Fred Hutchinson Cancer Research Center | Stable peptides and methods of use thereof |
| WO2018136614A1 (en) | 2017-01-18 | 2018-07-26 | Fred Hutchinson Cancer Research Center | Peptide compositions and methods of use thereof for disrupting tead interactions |
| EP3595699A4 (en) * | 2017-03-16 | 2020-12-23 | Blaze Bioscience, Inc. | PEPTIDIC CONJUGATES OF CARTILAGE ECOTROPISM AND THEIR METHODS OF USE |
| CA3059358A1 (en) | 2017-04-07 | 2018-10-11 | Massachusetts Institute Of Technology | Methods to spatially profile protease activity in tissue and sections |
| EP3638290A4 (en) * | 2017-06-15 | 2021-04-07 | Blaze Bioscience, Inc. | KIDNEY HOMING PEPTIDE CONJUGATES AND METHOD OF USING THEREOF |
| IT201700071296A1 (it) | 2017-06-26 | 2018-12-26 | Alda S R L | Nuovi reagenti per microscopia ottica |
| CA3086040A1 (en) | 2017-12-19 | 2019-06-27 | Blaze Bioscience, Inc. | Tumor homing and cell penetrating peptide-immuno-oncology agent complexes and methods of use thereof |
| AU2019233914A1 (en) * | 2018-03-16 | 2020-09-24 | Blaze Bioscience, Inc. | Truncated cartilage-homing peptides and peptide complexes and methods of use thereof |
| EP3784287A1 (en) * | 2018-04-23 | 2021-03-03 | Fred Hutchinson Cancer Research Center | Conjugates of cartilage-homing peptides |
| US12173349B2 (en) | 2018-09-25 | 2024-12-24 | Massachusetts Institute Of Technology | Lung protease nanosensors and uses thereof |
| US11835522B2 (en) | 2019-01-17 | 2023-12-05 | Massachusetts Institute Of Technology | Sensors for detecting and imaging of cancer metastasis |
| CN110357950B (zh) * | 2019-07-29 | 2023-04-25 | 武汉大学 | 酸性氨基酸扫描法设计的免疫抑制多肽及应用 |
| CN111454334B (zh) * | 2020-03-30 | 2021-12-14 | 东北农业大学 | 一种抗酶解的抗菌肽ii4ii及制备方法和应用 |
| CN111840512B (zh) * | 2020-07-15 | 2023-06-09 | 广州领晟医疗科技有限公司 | 治疗软骨修复和/或骨关节炎的组合物 |
| CN113332442A (zh) * | 2021-06-10 | 2021-09-03 | 愈美明德(成都)生物医药科技有限公司 | 一种靶向递送分子、粒子及其制备方法、应用 |
| CN118091163B (zh) * | 2024-04-26 | 2024-07-02 | 山东省食品药品检验研究院 | 一种鉴别尖刺信使蝎的特征多肽及其应用 |
| CN120865334A (zh) * | 2025-03-26 | 2025-10-31 | 中山大学附属第五医院 | 一种靶向软骨的阳离子肽类化合物及其制备方法与应用 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0932417T3 (da) | 1996-10-17 | 2003-04-14 | Immunomedics Inc | Non-antigent toxinkonjugat og fusionsprotein af internaliserende receptorsystem |
| WO2001053342A1 (en) | 2000-01-21 | 2001-07-26 | The Burnham Institute | Chimeric prostate-homing peptides with pro-apoptotic activity |
| WO2003020751A2 (en) | 2001-09-05 | 2003-03-13 | King's College London | Homing peptides |
| AU2003224773B2 (en) | 2002-03-26 | 2010-08-26 | The General Hospital Corporation | Combination therapy using trefoil peptides |
| US20060088899A1 (en) | 2002-05-31 | 2006-04-27 | Alvarez Vernon L | Combination chemotherapy with chlorotoxin |
| FR2877946B1 (fr) | 2004-11-12 | 2011-02-11 | Commissariat Energie Atomique | Peptides derives de la maurocalcine utilisables comme vecteurs pour l'adressage intracellulaire de molecules d'interet |
| CN101583370A (zh) | 2005-09-27 | 2009-11-18 | 阿穆尼克斯公司 | 蛋白质药物及其用途 |
| US7592009B2 (en) | 2006-10-10 | 2009-09-22 | Ecole Polytechnique Federale De Lausanne (Epfl) | Polypeptide ligands for targeting cartilage and methods of use thereof |
| JP5463013B2 (ja) * | 2007-06-19 | 2014-04-09 | 国立大学法人 岡山大学 | 軟骨マーカー |
| US20100215575A1 (en) | 2007-10-12 | 2010-08-26 | Transmolecular, Inc. | Systemic Administration of Chlorotoxin Agents for the Diagnosis and Treatment of Tumors |
| CN102844044B (zh) | 2010-02-04 | 2016-10-26 | 摩尔弗泰克有限公司 | 氯毒素多肽和结合物及其应用 |
| EP3165533B1 (en) | 2010-05-11 | 2020-04-08 | Fred Hutchinson Cancer Research Center | Chlorotoxin variants, conjugates and methods for their use |
| US20130280281A1 (en) | 2010-07-02 | 2013-10-24 | Jean-Paul Castaigne | Short and d-amino acid-containing polypeptides for therapeutic conjugates and uses thereof |
| US10844106B2 (en) | 2010-11-08 | 2020-11-24 | The Board Of Trustees Of The Leland Stanford Junior University | Fusion proteins comprising an engineered knottin peptide and uses thereof |
| US10426850B2 (en) | 2011-11-22 | 2019-10-01 | The Johns Hopkins University | Collagen mimetic peptides for targeting collagen strands for in vitro and in vivo imaging and therapeutic use |
| WO2013078250A2 (en) | 2011-11-22 | 2013-05-30 | The Board Of Trustees Of The Leland Stanford Junior University | Cystine knot peptides that bind alpha-v-beta-6 integrin |
| JP5724937B2 (ja) | 2012-04-23 | 2015-05-27 | ニプロ株式会社 | 腎臓集積性を示すペプチド、製剤 |
| US8945553B2 (en) | 2012-05-22 | 2015-02-03 | Bristol-Myers Squibb Company | Bispecific antibodies to IL-23 and IL-17A/F |
| CN104619727B (zh) | 2012-06-25 | 2019-04-05 | 布里格姆及妇女医院股份有限公司 | 靶向治疗 |
| US9587001B2 (en) | 2012-10-19 | 2017-03-07 | The Board Of Trustees Of The Leland Stanford Junior University | Conjugated knottin mini-proteins containing non-natural amino acids |
| CA2913029A1 (en) * | 2012-12-10 | 2014-06-19 | Fred Hutchinson Cancer Research Center | Lipocalin fusion partners |
| US20160084839A1 (en) | 2013-04-02 | 2016-03-24 | Marisa Dolled-Filhart | Immunohistochemical assay for detecting expression of programmed death ligand 1 (pd-l1) in tumor tissue |
| CN105188728B (zh) | 2013-05-07 | 2021-11-09 | 默克专利股份有限公司 | 用于肾靶向的肽和肽-活性物质-缀合物 |
| US9937230B2 (en) * | 2013-07-22 | 2018-04-10 | Kineta One, Llc | Ophthalmic uses of toxin-based therapeutic peptides and pharmaceutical compositions thereof |
| WO2015075699A1 (en) * | 2013-11-25 | 2015-05-28 | Sanofi | Dotam derivatives for therapeutic use |
| WO2015100370A2 (en) | 2013-12-23 | 2015-07-02 | Kineta One, Llc | Sustained release depot formulations of therapeutic proteins, and uses thereof |
| CA2949535C (en) | 2014-05-21 | 2023-09-12 | President And Fellows Of Harvard College | Ras inhibitory peptides and uses thereof |
| CN107405388A (zh) | 2015-01-08 | 2017-11-28 | 衣阿华大学研究基金会 | 用于体内关节软骨再生的方法 |
| WO2016112208A2 (en) | 2015-01-09 | 2016-07-14 | Kineta One, Llp | Topical applications of kv1.3 channel blocking peptides to treat skin inflammation |
| WO2016118859A1 (en) | 2015-01-22 | 2016-07-28 | Board Of Trustees Of The University Of Arkansas | Compositions and methods for selectively depleting senescent cells comprising flip |
| CA2987636A1 (en) | 2015-06-26 | 2016-12-29 | Fred Hutchinson Cancer Research Center | Therapeutic peptides and methods of use thereof |
| CN112574316A (zh) | 2015-07-02 | 2021-03-30 | 博际生物医药科技(杭州)有限公司 | 用于肿瘤靶向治疗的白细胞介素-15融合蛋白 |
| WO2017044894A2 (en) | 2015-09-09 | 2017-03-16 | Fred Hutchinson Cancer Research Center | Cartilage-homing peptides |
| EP3386530A4 (en) | 2015-12-11 | 2019-08-28 | Fred Hutchinson Cancer Research Center | PEPTIDES FOR KIDNEY THERAPY |
| WO2017143259A1 (en) | 2016-02-19 | 2017-08-24 | Dignity Health | Antibody fusion protein and related compositions for targeting cancer |
| CA3033004A1 (en) | 2016-09-09 | 2018-03-15 | Fred Hutchinson Cancer Research Center | Stable peptides and methods of use thereof |
| US20200188528A1 (en) | 2016-12-19 | 2020-06-18 | Fred Hutchinson Cancer Research Center | Peptide-antibody compositions and methods of use thereof |
| WO2018136614A1 (en) | 2017-01-18 | 2018-07-26 | Fred Hutchinson Cancer Research Center | Peptide compositions and methods of use thereof for disrupting tead interactions |
| EP3595699A4 (en) | 2017-03-16 | 2020-12-23 | Blaze Bioscience, Inc. | PEPTIDIC CONJUGATES OF CARTILAGE ECOTROPISM AND THEIR METHODS OF USE |
| EP3638290A4 (en) | 2017-06-15 | 2021-04-07 | Blaze Bioscience, Inc. | KIDNEY HOMING PEPTIDE CONJUGATES AND METHOD OF USING THEREOF |
-
2016
- 2016-09-09 WO PCT/US2016/051166 patent/WO2017044894A2/en not_active Ceased
- 2016-09-09 CA CA2994865A patent/CA2994865A1/en not_active Abandoned
- 2016-09-09 BR BR112018004536A patent/BR112018004536A2/pt not_active IP Right Cessation
- 2016-09-09 AU AU2016321342A patent/AU2016321342A1/en not_active Abandoned
- 2016-09-09 CN CN201680053482.4A patent/CN108135970B/zh not_active Expired - Fee Related
- 2016-09-09 US US15/758,320 patent/US11090358B2/en active Active
- 2016-09-09 EP EP16845226.6A patent/EP3347035A4/en not_active Withdrawn
- 2016-09-09 JP JP2018510741A patent/JP6966424B2/ja not_active Expired - Fee Related
-
2018
- 2018-02-07 IL IL257396A patent/IL257396B/en active IP Right Grant
-
2021
- 2021-06-21 US US17/353,447 patent/US11648290B2/en active Active
- 2021-10-21 JP JP2021172263A patent/JP7378449B2/ja active Active
-
2023
- 2023-03-02 US US18/177,642 patent/US20230364183A1/en not_active Abandoned
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