JP2020510698A5 - - Google Patents
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- JP2020510698A5 JP2020510698A5 JP2019568815A JP2019568815A JP2020510698A5 JP 2020510698 A5 JP2020510698 A5 JP 2020510698A5 JP 2019568815 A JP2019568815 A JP 2019568815A JP 2019568815 A JP2019568815 A JP 2019568815A JP 2020510698 A5 JP2020510698 A5 JP 2020510698A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- polypeptide
- amino acid
- hla class
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 170
- 102000004196 processed proteins & peptides Human genes 0.000 claims 160
- 229920001184 polypeptide Polymers 0.000 claims 155
- 125000003275 alpha amino acid group Chemical group 0.000 claims 74
- 210000001744 T-lymphocyte Anatomy 0.000 claims 59
- 239000000427 antigen Substances 0.000 claims 46
- 102000036639 antigens Human genes 0.000 claims 46
- 108091007433 antigens Proteins 0.000 claims 46
- 238000000034 method Methods 0.000 claims 34
- 239000004480 active ingredient Substances 0.000 claims 30
- 239000008194 pharmaceutical composition Substances 0.000 claims 27
- 239000012634 fragment Substances 0.000 claims 24
- 206010028980 Neoplasm Diseases 0.000 claims 18
- 201000011510 cancer Diseases 0.000 claims 18
- 230000005867 T cell response Effects 0.000 claims 16
- 210000004027 cell Anatomy 0.000 claims 16
- 230000004044 response Effects 0.000 claims 15
- 150000001413 amino acids Chemical class 0.000 claims 14
- 230000002163 immunogen Effects 0.000 claims 10
- 210000002443 helper t lymphocyte Anatomy 0.000 claims 9
- 229940076838 Immune checkpoint inhibitor Drugs 0.000 claims 8
- 230000028993 immune response Effects 0.000 claims 8
- 239000012274 immune-checkpoint protein inhibitor Substances 0.000 claims 8
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 7
- 238000011282 treatment Methods 0.000 claims 7
- 208000023275 Autoimmune disease Diseases 0.000 claims 6
- 230000001939 inductive effect Effects 0.000 claims 5
- 102000039446 nucleic acids Human genes 0.000 claims 5
- 108020004707 nucleic acids Proteins 0.000 claims 5
- 150000007523 nucleic acids Chemical class 0.000 claims 5
- 239000003814 drug Substances 0.000 claims 4
- 241000700605 Viruses Species 0.000 claims 3
- 230000002411 adverse Effects 0.000 claims 3
- 239000013566 allergen Substances 0.000 claims 3
- 239000003085 diluting agent Substances 0.000 claims 3
- 239000003112 inhibitor Substances 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 244000052769 pathogen Species 0.000 claims 3
- 239000003755 preservative agent Substances 0.000 claims 3
- 230000002335 preservative effect Effects 0.000 claims 3
- 230000006472 autoimmune response Effects 0.000 claims 2
- -1 carrier Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000035772 mutation Effects 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 238000002512 chemotherapy Methods 0.000 claims 1
- 230000001627 detrimental effect Effects 0.000 claims 1
- 238000001647 drug administration Methods 0.000 claims 1
- 230000005746 immune checkpoint blockade Effects 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
- 238000011321 prophylaxis Methods 0.000 claims 1
- 238000002626 targeted therapy Methods 0.000 claims 1
- 230000008685 targeting Effects 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17159242.1A EP3369431A1 (en) | 2017-03-03 | 2017-03-03 | Vaccine |
| EP17159243.9A EP3370065A1 (en) | 2017-03-03 | 2017-03-03 | Immunogenic peptides |
| EP17159243.9 | 2017-03-03 | ||
| EP17159242.1 | 2017-03-03 | ||
| GBGB1703809.2A GB201703809D0 (en) | 2017-03-09 | 2017-03-09 | Vaccine |
| GB1703809.2 | 2017-03-09 | ||
| PCT/EP2018/055231 WO2018158456A1 (en) | 2017-03-03 | 2018-03-02 | Personalised immunogenic peptide identification platform |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020510698A JP2020510698A (ja) | 2020-04-09 |
| JP2020510698A5 true JP2020510698A5 (cg-RX-API-DMAC7.html) | 2021-04-15 |
Family
ID=61386864
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019568815A Pending JP2020510698A (ja) | 2017-03-03 | 2018-03-02 | 個別化された免疫原性ペプチドの同定のプラットフォーム |
| JP2019568814A Active JP7751374B2 (ja) | 2017-03-03 | 2018-03-02 | ペプチドワクチン |
| JP2019568816A Active JP7437939B2 (ja) | 2017-03-03 | 2018-03-02 | 集団に基づいた免疫原性ペプチドの同定のプラットフォーム |
| JP2022197534A Pending JP2023051941A (ja) | 2017-03-03 | 2022-12-09 | ペプチドワクチン |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019568814A Active JP7751374B2 (ja) | 2017-03-03 | 2018-03-02 | ペプチドワクチン |
| JP2019568816A Active JP7437939B2 (ja) | 2017-03-03 | 2018-03-02 | 集団に基づいた免疫原性ペプチドの同定のプラットフォーム |
| JP2022197534A Pending JP2023051941A (ja) | 2017-03-03 | 2022-12-09 | ペプチドワクチン |
Country Status (16)
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7362249B2 (ja) * | 2015-03-20 | 2023-10-17 | チルドレンズ ナショナル メディカル センター | ナイーブｔ細胞集団からのウイルスまたは他の抗原に特異的なｔ細胞の生成 |
| CA3054871A1 (en) * | 2017-03-03 | 2018-09-07 | Treos Bio Zrt | Population-based immunogenic peptide identification platform |
| GB201814362D0 (en) * | 2018-09-04 | 2018-10-17 | Treos Bio Zrt | Composition and process for preparing vaccine |
| GB201814361D0 (en) * | 2018-09-04 | 2018-10-17 | Treos Bio Zrt | Immunogenetic cancer screening test |
| KR20210086612A (ko) | 2018-09-04 | 2021-07-08 | 트레오스 바이오 리미티드 | 펩타이드 백신 |
| TW202028224A (zh) * | 2018-09-17 | 2020-08-01 | 德商英麥提克生物技術股份有限公司 | B*44限制肽在抗癌免疫治療的用途和相關方法 |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| TW202039535A (zh) * | 2018-12-18 | 2020-11-01 | 德商英麥提克生物技術股份有限公司 | B*08限制肽和肽組合物抗癌免疫治療和相關方法 |
| WO2021156404A2 (en) * | 2020-02-07 | 2021-08-12 | Isa Pharmaceuticals | Treatment of hpv-related diseases |
| KR102159921B1 (ko) * | 2020-03-24 | 2020-09-25 | 주식회사 테라젠바이오 | 펩타이드 서열 및 hla 대립유전자 서열을 이용하여 신생항원을 예측하는 방법 및 컴퓨터 프로그램 |
| GB202004974D0 (en) | 2020-04-03 | 2020-05-20 | Treos Bio Ltd | Coronavirus vaccine |
| CA3174505A1 (en) | 2020-04-03 | 2021-10-07 | Zsolt CSISZOVSZKI | Coronavirus vaccine |
| AU2020443560B2 (en) * | 2020-04-20 | 2024-03-21 | Nec Corporation | A method and a system for optimal vaccine design |
| CN112048001B (zh) * | 2020-09-08 | 2022-04-05 | 南方科技大学 | 一种肿瘤新生抗原多肽及其应用 |
| KR102278727B1 (ko) * | 2020-09-16 | 2021-07-19 | 주식회사 테라젠바이오 | 대상 암 조직 및 세포 유리형 dna 유래 펩타이드 서열 및 hla 클래스 ii 대립유전자 서열을 이용하여 신생항원을 예측하는 방법 및 컴퓨터 프로그램 |
| EP4386762A4 (en) | 2021-08-10 | 2024-11-13 | NEC Corporation | INFORMATION PROCESSING SYSTEM AND INFORMATION PROCESSING METHOD |
| TWI898159B (zh) | 2021-10-04 | 2025-09-21 | 日商日本電氣股份有限公司 | 管理方法、管理系統及電子健康紀錄系統 |
| US20240424094A1 (en) * | 2021-10-06 | 2024-12-26 | CancerVAX Inc. | Methods and compositions for cancer treatment |
| US20250297036A1 (en) * | 2022-04-27 | 2025-09-25 | POSTECH Research and Business Development Foundation | Method for constructing hotspot-derived peptide-nucleic acid hybrid molecules on basis of in vitro selection |
| CN115785203B (zh) * | 2022-06-10 | 2024-03-12 | 河北博海生物工程开发有限公司 | 肺癌特异性分子靶标10及其用途 |
| EP4575867A4 (en) | 2022-08-17 | 2025-10-01 | Nec Corp | INFORMATION PROCESSING SYSTEM, INFORMATION PROCESSING METHOD, AND PROGRAM |
| GB202216453D0 (en) | 2022-11-04 | 2022-12-21 | Lisziewicz Julianna | Identification of antigens which induce t-cell responses |
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| US6617434B1 (en) * | 1996-05-31 | 2003-09-09 | North Shore Long Island Jewish Research Institute | Identificiaton of differentially methylated and mutated nucleic acids |
| US20030148463A1 (en) | 1997-04-14 | 2003-08-07 | Micromet Ag | Novel method for the production of anti-human antigen receptors and uses thereof |
| US7227002B1 (en) * | 1997-04-14 | 2007-06-05 | Micromet Ag | Human antibodies that bind human 17-A1/EpCAM tumor antigen |
| FR2791895B1 (fr) | 1999-03-23 | 2001-06-15 | Pasteur Merieux Serums Vacc | Utilisation de trehalose pour stabiliser un vaccin liquide |
| AUPQ776100A0 (en) | 2000-05-26 | 2000-06-15 | Australian National University, The | Synthetic molecules and uses therefor |
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| US20210213066A1 (en) | 2018-05-18 | 2021-07-15 | Children's National Medical Center | Improved cell therapy compositions for hematopoietic stem cell transplant patients |
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| GB201814362D0 (en) | 2018-09-04 | 2018-10-17 | Treos Bio Zrt | Composition and process for preparing vaccine |
| KR20210086612A (ko) | 2018-09-04 | 2021-07-08 | 트레오스 바이오 리미티드 | 펩타이드 백신 |
| GB201814361D0 (en) | 2018-09-04 | 2018-10-17 | Treos Bio Zrt | Immunogenetic cancer screening test |
| US20220064598A1 (en) | 2019-01-07 | 2022-03-03 | Children's National Medical Center | Ex vivo activated t-lymphocytic compositions and methods of using the same |
| EP3908292A4 (en) | 2019-01-07 | 2023-01-04 | Children's National Medical Center | IMPROVED TARGETED T-CELL THERAPY FOR THE TREATMENT OF MULTIPLE MYELOMA |
| GB202004974D0 (en) | 2020-04-03 | 2020-05-20 | Treos Bio Ltd | Coronavirus vaccine |
-
2018
- 2018-03-02 CA CA3054871A patent/CA3054871A1/en active Pending
- 2018-03-02 MA MA047683A patent/MA47683A/fr unknown
- 2018-03-02 WO PCT/EP2018/055230 patent/WO2018158455A1/en not_active Ceased
- 2018-03-02 JP JP2019568815A patent/JP2020510698A/ja active Pending
- 2018-03-02 US US15/910,930 patent/US20180264094A1/en not_active Abandoned
- 2018-03-02 CN CN201880014727.1A patent/CN110651188B/zh active Active
- 2018-03-02 WO PCT/EP2018/055231 patent/WO2018158456A1/en not_active Ceased
- 2018-03-02 SG SG11201907524UA patent/SG11201907524UA/en unknown
- 2018-03-02 WO PCT/EP2018/055232 patent/WO2018158457A1/en not_active Ceased
- 2018-03-02 MX MX2019010461A patent/MX2019010461A/es unknown
- 2018-03-02 CN CN202411399993.4A patent/CN119371510A/zh active Pending
- 2018-03-02 KR KR1020247034375A patent/KR20240156643A/ko active Pending
- 2018-03-02 AU AU2018226566A patent/AU2018226566B2/en active Active
- 2018-03-02 BR BR112019018313A patent/BR112019018313A2/pt unknown
- 2018-03-02 EP EP18710392.4A patent/EP3589951A1/en active Pending
- 2018-03-02 KR KR1020197029092A patent/KR102549625B1/ko active Active
- 2018-03-02 US US15/910,988 patent/US10213497B2/en active Active
- 2018-03-02 CA CA3054866A patent/CA3054866A1/en active Pending
- 2018-03-02 MA MA047678A patent/MA47678A/fr unknown
- 2018-03-02 BR BR112019018307-8A patent/BR112019018307A2/pt unknown
- 2018-03-02 AU AU2018228786A patent/AU2018228786B2/en active Active
- 2018-03-02 JP JP2019568814A patent/JP7751374B2/ja active Active
- 2018-03-02 EP EP18707725.0A patent/EP3589310A1/en active Pending
- 2018-03-02 MX MX2019010459A patent/MX2019010459A/es unknown
- 2018-03-02 SG SG11201907402SA patent/SG11201907402SA/en unknown
- 2018-03-02 KR KR1020197029093A patent/KR102723248B1/ko active Active
- 2018-03-02 US US15/910,965 patent/US20180264095A1/en not_active Abandoned
- 2018-03-02 JP JP2019568816A patent/JP7437939B2/ja active Active
- 2018-03-02 CN CN201880014739.4A patent/CN110621334A/zh active Pending
- 2018-03-02 BR BR112019018312-4A patent/BR112019018312A2/pt unknown
- 2018-03-02 IL IL268919A patent/IL268919B2/en unknown
- 2018-03-02 IL IL268920A patent/IL268920B2/en unknown
- 2018-03-02 MX MX2019010460A patent/MX2019010460A/es unknown
- 2018-03-02 EP EP18707724.3A patent/EP3589954A1/en active Pending
- 2018-03-02 AU AU2018228785A patent/AU2018228785B2/en active Active
- 2018-03-02 CA CA3054861A patent/CA3054861A1/en active Pending
- 2018-03-02 SG SG11201906765UA patent/SG11201906765UA/en unknown
- 2018-03-02 MA MA047677A patent/MA47677A/fr unknown
- 2018-03-02 CN CN201880014745.XA patent/CN110651189B/zh active Active
- 2018-03-02 KR KR1020197029094A patent/KR102591136B1/ko active Active
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2019
- 2019-01-10 US US16/244,497 patent/US11213578B2/en active Active
- 2019-07-18 ZA ZA2019/04725A patent/ZA201904725B/en unknown
- 2019-07-18 ZA ZA2019/04723A patent/ZA201904723B/en unknown
- 2019-08-26 IL IL268917A patent/IL268917B2/en unknown
- 2019-09-03 CL CL2019002534A patent/CL2019002534A1/es unknown
- 2019-09-03 CL CL2019002533A patent/CL2019002533A1/es unknown
- 2019-09-03 CL CL2019002532A patent/CL2019002532A1/es unknown
- 2019-09-26 CO CONC2019/0010503A patent/CO2019010503A2/es unknown
- 2019-09-26 CO CONC2019/0010524A patent/CO2019010524A2/es unknown
- 2019-09-27 CO CONC2019/0010698A patent/CO2019010698A2/es unknown
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2021
- 2021-09-17 US US17/448,020 patent/US20220031823A1/en not_active Abandoned
- 2021-11-09 US US17/454,225 patent/US20220072114A1/en not_active Abandoned
- 2021-12-22 US US17/645,737 patent/US11426452B2/en active Active
- 2021-12-22 US US17/645,741 patent/US11628211B2/en active Active
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2022
- 2022-10-14 CL CL2022002836A patent/CL2022002836A1/es unknown
- 2022-12-09 JP JP2022197534A patent/JP2023051941A/ja active Pending
-
2023
- 2023-02-08 US US18/166,420 patent/US20230405100A1/en active Pending
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