CO2019010524A2 - Plataforma de identificación de péptidos inmunogénicos basada en población - Google Patents

Plataforma de identificación de péptidos inmunogénicos basada en población

Info

Publication number
CO2019010524A2
CO2019010524A2 CONC2019/0010524A CO2019010524A CO2019010524A2 CO 2019010524 A2 CO2019010524 A2 CO 2019010524A2 CO 2019010524 A CO2019010524 A CO 2019010524A CO 2019010524 A2 CO2019010524 A2 CO 2019010524A2
Authority
CO
Colombia
Prior art keywords
population
methods
immunogenic peptide
identification platform
peptide identification
Prior art date
Application number
CONC2019/0010524A
Other languages
English (en)
Inventor
József Toth
Orsolya Lorincz
Eszter Somogyi
Mónika Megyesi
Julianna Lisziewicz
Levente Molnár
Enikő R Tőke
Zsolt Csiszovszki
Katalin Pántya
Original Assignee
Treos Bio Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=61386864&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO2019010524(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP17159242.1A external-priority patent/EP3369431A1/en
Priority claimed from EP17159243.9A external-priority patent/EP3370065A1/en
Priority claimed from GBGB1703809.2A external-priority patent/GB201703809D0/en
Application filed by Treos Bio Zrt filed Critical Treos Bio Zrt
Publication of CO2019010524A2 publication Critical patent/CO2019010524A2/es

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    • A61K39/0011—Cancer antigens
    • A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
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    • G01N33/56977—HLA or MHC typing
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    • G01—MEASURING; TESTING
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G16B15/30—Drug targeting using structural data; Docking or binding prediction
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K2039/55588—Adjuvants of undefined constitution
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    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)

Abstract

La descripción se refiere a métodos para identificar fragmentos de un polipéptido que son inmunogénicos para un sujeto humano específico, métodos para preparar composiciones farmacéuticas que comprenden dichos fragmentos de polipéptido, composiciones farmacéuticas que comprenden dichos fragmentos de polipéptido y métodos de tratamiento que utilizan dichas composiciones. Los métodos comprenden identificar un fragmento del polipéptido que se une a múltiples HLA de sujetos individuales.
CONC2019/0010524A 2017-03-03 2019-09-26 Plataforma de identificación de péptidos inmunogénicos basada en población CO2019010524A2 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP17159242.1A EP3369431A1 (en) 2017-03-03 2017-03-03 Vaccine
EP17159243.9A EP3370065A1 (en) 2017-03-03 2017-03-03 Immunogenic peptides
GBGB1703809.2A GB201703809D0 (en) 2017-03-09 2017-03-09 Vaccine
PCT/EP2018/055232 WO2018158457A1 (en) 2017-03-03 2018-03-02 Population-based immunogenic peptide identification platform

Publications (1)

Publication Number Publication Date
CO2019010524A2 true CO2019010524A2 (es) 2020-01-17

Family

ID=61386864

Family Applications (3)

Application Number Title Priority Date Filing Date
CONC2019/0010524A CO2019010524A2 (es) 2017-03-03 2019-09-26 Plataforma de identificación de péptidos inmunogénicos basada en población
CONC2019/0010503A CO2019010503A2 (es) 2017-03-03 2019-09-26 Plataforma de identificación de péptidos inmunogénicos personalizada
CONC2019/0010698A CO2019010698A2 (es) 2017-03-03 2019-09-27 Vacunas de peptidos

Family Applications After (2)

Application Number Title Priority Date Filing Date
CONC2019/0010503A CO2019010503A2 (es) 2017-03-03 2019-09-26 Plataforma de identificación de péptidos inmunogénicos personalizada
CONC2019/0010698A CO2019010698A2 (es) 2017-03-03 2019-09-27 Vacunas de peptidos

Country Status (16)

Country Link
US (9) US20180264095A1 (es)
EP (3) EP3589310A1 (es)
JP (4) JP2020510698A (es)
KR (3) KR102549625B1 (es)
CN (3) CN110651188B (es)
AU (3) AU2018228785A1 (es)
BR (3) BR112019018312A2 (es)
CA (3) CA3054861A1 (es)
CL (4) CL2019002534A1 (es)
CO (3) CO2019010524A2 (es)
IL (3) IL268919B2 (es)
MA (3) MA47683A (es)
MX (3) MX2019010460A (es)
SG (3) SG11201907402SA (es)
WO (3) WO2018158455A1 (es)
ZA (2) ZA201904723B (es)

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CN112048001B (zh) * 2020-09-08 2022-04-05 南方科技大学 一种肿瘤新生抗原多肽及其应用
KR102278727B1 (ko) * 2020-09-16 2021-07-19 주식회사 테라젠바이오 대상 암 조직 및 세포 유리형 dna 유래 펩타이드 서열 및 hla 클래스 ii 대립유전자 서열을 이용하여 신생항원을 예측하는 방법 및 컴퓨터 프로그램
JPWO2023017768A1 (es) 2021-08-10 2023-02-16
TW202322137A (zh) 2021-10-04 2023-06-01 日商日本電氣股份有限公司 管理方法、管理系統及電子健康紀錄系統
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WO2023211024A1 (ko) * 2022-04-27 2023-11-02 포항공과대학교 산학협력단 시험관 진화 기반 핫스팟 유래 펩타이드-핵산 하이브리드 분자 제조방법
CN115785203B (zh) * 2022-06-10 2024-03-12 河北博海生物工程开发有限公司 肺癌特异性分子靶标10及其用途

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