JP2020507744A5 - - Google Patents

Download PDF

Info

Publication number
JP2020507744A5
JP2020507744A5 JP2019533657A JP2019533657A JP2020507744A5 JP 2020507744 A5 JP2020507744 A5 JP 2020507744A5 JP 2019533657 A JP2019533657 A JP 2019533657A JP 2019533657 A JP2019533657 A JP 2019533657A JP 2020507744 A5 JP2020507744 A5 JP 2020507744A5
Authority
JP
Japan
Prior art keywords
light source
light
sample
detection vessel
angle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019533657A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020507744A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2017/045823 external-priority patent/WO2018117191A1/en
Publication of JP2020507744A publication Critical patent/JP2020507744A/ja
Publication of JP2020507744A5 publication Critical patent/JP2020507744A5/ja
Priority to JP2022140509A priority Critical patent/JP7425138B2/ja
Priority to JP2024005071A priority patent/JP7713044B2/ja
Pending legal-status Critical Current

Links

JP2019533657A 2016-12-21 2017-12-20 デジタルアッセイのために横からの照射を使用した光学イメージングシステム Pending JP2020507744A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022140509A JP7425138B2 (ja) 2016-12-21 2022-09-05 デジタルアッセイのために横からの照射を使用した光学イメージングシステム
JP2024005071A JP7713044B2 (ja) 2016-12-21 2024-01-17 デジタルアッセイのために横からの照射を使用した光学イメージングシステム

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662437534P 2016-12-21 2016-12-21
US62/437,534 2016-12-21
PCT/JP2017/045823 WO2018117191A1 (en) 2016-12-21 2017-12-20 Optical imaging system using lateral illumination for digital assays

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022140509A Division JP7425138B2 (ja) 2016-12-21 2022-09-05 デジタルアッセイのために横からの照射を使用した光学イメージングシステム

Publications (2)

Publication Number Publication Date
JP2020507744A JP2020507744A (ja) 2020-03-12
JP2020507744A5 true JP2020507744A5 (enExample) 2021-02-04

Family

ID=62556312

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019533657A Pending JP2020507744A (ja) 2016-12-21 2017-12-20 デジタルアッセイのために横からの照射を使用した光学イメージングシステム
JP2022140509A Active JP7425138B2 (ja) 2016-12-21 2022-09-05 デジタルアッセイのために横からの照射を使用した光学イメージングシステム
JP2024005071A Active JP7713044B2 (ja) 2016-12-21 2024-01-17 デジタルアッセイのために横からの照射を使用した光学イメージングシステム

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2022140509A Active JP7425138B2 (ja) 2016-12-21 2022-09-05 デジタルアッセイのために横からの照射を使用した光学イメージングシステム
JP2024005071A Active JP7713044B2 (ja) 2016-12-21 2024-01-17 デジタルアッセイのために横からの照射を使用した光学イメージングシステム

Country Status (5)

Country Link
US (3) US10324041B2 (enExample)
EP (1) EP3559640A4 (enExample)
JP (3) JP2020507744A (enExample)
CN (1) CN110366677A (enExample)
WO (1) WO2018117191A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4142940A1 (en) * 2020-04-29 2023-03-08 Abbott Laboratories Systems and methods for sample analysis
US20240168023A1 (en) * 2021-03-26 2024-05-23 National Institute Of Advanced Industrial Science And Technology Virus detection method using well array, well array, and detection device
JP7626121B2 (ja) 2022-10-27 2025-02-04 セイコーエプソン株式会社 投射方法、処理装置、プロジェクションシステム、及びプログラム
WO2025096384A1 (en) * 2023-10-31 2025-05-08 Board Of Regents For The Oklahoma Agricultural And Mechanical Colleges Colorimetric insulin immunosensor and methods of producing and using same
WO2025111479A1 (en) * 2023-11-21 2025-05-30 Abbott Laboratories Fluorogenic substrates and methods of use

Family Cites Families (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5026159A (en) 1989-05-19 1991-06-25 Acrogen, Inc. Area-modulated luminescence (AML)
US5162990A (en) 1990-06-15 1992-11-10 The United States Of America As Represented By The United States Navy System and method for quantifying macrophage phagocytosis by computer image analysis
US5260578A (en) 1991-04-10 1993-11-09 Mayo Foundation For Medical Education And Research Confocal imaging system for visible and ultraviolet light
JP3324780B2 (ja) 1991-05-16 2002-09-17 オリンパス光学工業株式会社 紫外線顕微鏡
JP3326708B2 (ja) 1993-08-31 2002-09-24 日水製薬株式会社 光学的測定装置およびその方法
US5620850A (en) 1994-09-26 1997-04-15 President And Fellows Of Harvard College Molecular recognition at surfaces derivatized with self-assembled monolayers
US5880473A (en) 1997-07-28 1999-03-09 Applied Imaging, Inc. Multifluor-fluorescence in-situ hybridization (M-FISH) imaging techniques using multiple multiband filters with image registration
US6023540A (en) 1997-03-14 2000-02-08 Trustees Of Tufts College Fiber optic sensor with encoded microspheres
US6259807B1 (en) 1997-05-14 2001-07-10 Applied Imaging Corp. Identification of objects of interest using multiple illumination schemes and finding overlap of features in corresponding multiple images
US6169816B1 (en) 1997-05-14 2001-01-02 Applied Imaging, Inc. Identification of objects of interest using multiple illumination schemes and finding overlap of features in corresponding multiple images
US7070921B2 (en) 2000-04-28 2006-07-04 Molecular Devices Corporation Molecular modification assays
US7632651B2 (en) 1997-09-15 2009-12-15 Mds Analytical Technologies (Us) Inc. Molecular modification assays
EP1067199A4 (en) 1998-12-28 2006-09-27 Sapporo Breweries METHOD FOR COUNTING MICROORGANISMS AND DEVICE FOR PERFORMING SAID COUNT
US6867851B2 (en) * 1999-11-04 2005-03-15 Regents Of The University Of Minnesota Scanning of biological samples
EP2338515A3 (en) 2000-02-10 2011-11-16 Abbott Laboratories Antibodies that bind human interleukin-18 and methods of making and using
US6734420B2 (en) * 2000-04-06 2004-05-11 Quantum Dot Corporation Differentiable spectral bar code methods and systems
JP2003532123A (ja) * 2000-04-28 2003-10-28 エッジライト バイオサイエンシズ インコーポレイテッド マイクロアレーエバネッセント波蛍光検出装置
WO2002068932A2 (en) * 2001-02-23 2002-09-06 Genicon Sciences Corporation Methods for providing extended dynamic range in analyte assays
DE60228165D1 (de) * 2001-05-16 2008-09-25 Olympus Corp Endoskop mit Bildverarbeitungseinrichtung
US7280207B2 (en) * 2001-07-25 2007-10-09 Applera Corporation Time-delay integration in a flow cytometry system
ES2635912T3 (es) * 2001-09-06 2017-10-05 Rapid Micro Biosystems, Inc. Detección rápida de células en replicación
EP1452866A1 (en) 2001-10-05 2004-09-01 BML, Inc. Sensing board
US7272252B2 (en) 2002-06-12 2007-09-18 Clarient, Inc. Automated system for combining bright field and fluorescent microscopy
US7050613B2 (en) 2002-11-07 2006-05-23 Fujitsu Limited Method for supporting cell image analysis
US7597936B2 (en) 2002-11-26 2009-10-06 University Of Utah Research Foundation Method of producing a pigmented composite microporous material
JP3727026B2 (ja) 2003-04-10 2005-12-14 博行 野地 一分子酵素活性検出に用いられるマイクロチャンバと1000fL以下の液滴を調製する方法
US7224468B2 (en) * 2003-10-20 2007-05-29 Agilent Technologies, Inc. En-face functional imaging using multiple wavelengths
JP2005147826A (ja) 2003-11-14 2005-06-09 Hamamatsu Photonics Kk 蛍光測定装置
JP4041458B2 (ja) * 2003-12-12 2008-01-30 日立ソフトウエアエンジニアリング株式会社 蛍光ビーズ検出方法及び蛍光ビーズ検出装置
EP1731941B1 (en) * 2004-03-31 2013-05-01 Olympus Corporation Observing device and fluorescent light observing device
JP4599941B2 (ja) 2004-08-20 2010-12-15 株式会社ニコン 自動焦点検出装置およびこれを備える顕微鏡システム
WO2006047038A1 (en) 2004-09-28 2006-05-04 Trustees Of Tufts College Apparatus and method for cell migration assays
JP2006098129A (ja) * 2004-09-28 2006-04-13 Aisin Seiki Co Ltd マイクロチャネルチップシステム及び検出チップ
US7602952B2 (en) 2004-11-16 2009-10-13 Illumina, Inc. Scanner having spatial light modulator
JP2006194730A (ja) 2005-01-13 2006-07-27 Moritex Corp エバネッセント波励起蛍光検出方法
JP4733433B2 (ja) * 2005-06-03 2011-07-27 株式会社日立ソリューションズ ビーズアレイ用蛍光読取装置及びビーズアレイ用蛍光読取方法
EP1929274B1 (en) 2005-09-21 2016-07-27 Luminex Corporation Methods and systems for image data processing
US7749722B2 (en) 2005-12-15 2010-07-06 Mitsubishi Kagaku Istron, Inc. Measuring method using whole blood
MX2008008280A (es) * 2005-12-21 2008-11-06 Meso Scale Technologies Llc Modulos de ensayo que tienen reactivos de ensayo y metodos para hacer y utilizar los mismos.
US8492098B2 (en) 2006-02-21 2013-07-23 The Trustees Of Tufts College Methods and arrays for target analyte detection and determination of reaction components that affect a reaction
KR20090004925A (ko) * 2006-03-09 2009-01-12 테사레 엘엘씨 마이크로어레이 영상 시스템 및 관련 방법론
US7838250B1 (en) 2006-04-04 2010-11-23 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
US8296088B2 (en) 2006-06-02 2012-10-23 Luminex Corporation Systems and methods for performing measurements of one or more materials
US7764361B2 (en) * 2006-07-27 2010-07-27 Northwestern University Systems and methods to analyze multiplexed bead-based assays using backscattered light
JP5074044B2 (ja) * 2007-01-18 2012-11-14 オリンパス株式会社 蛍光観察装置および蛍光観察装置の作動方法
US7659968B2 (en) * 2007-01-19 2010-02-09 Purdue Research Foundation System with extended range of molecular sensing through integrated multi-modal data acquisition
US7700928B2 (en) * 2007-01-25 2010-04-20 Etaluma, Inc. Apparatus and method for interleaving detection of fluorescence and luminescence
US20080240543A1 (en) * 2007-03-30 2008-10-02 Wolfgang Ernst Gustav Budach Calibration and normalization method for biosensors
EP1978363B1 (en) 2007-04-03 2010-02-24 Sysmex Corporation Immunoassay method, reagent kit for detecting alkaline phosphatase, and reagent kit for immunoassay
US8013991B2 (en) * 2007-08-08 2011-09-06 Chemimage Corporation Raman difference spectra based disease classification
US20120078524A1 (en) * 2007-08-08 2012-03-29 Chemlmage Corporation System and method for diagnosis tissue samples using fluorescence and raman techniques
ES2556627T3 (es) 2007-08-30 2016-01-19 Trustees Of Tufts College Métodos para determinar la concentración de un analito en solución
WO2009053902A2 (en) * 2007-10-25 2009-04-30 Koninklijke Philips Electronics N. V. Sensor device for target particles in a sample
US20090137058A1 (en) * 2007-11-28 2009-05-28 General Electric Company Chemical and biological detection method and device based on measurements of fluorescence and reflectivity
US8791427B2 (en) 2007-12-26 2014-07-29 Olympus Corporation Biological-specimen observation apparatus
BRPI0913786A2 (pt) * 2008-09-25 2015-10-20 Koninkl Philips Electronics Nv sistema de detecção e método de detecção
DE102008054317A1 (de) 2008-11-03 2010-05-06 Carl Zeiss Microlmaging Gmbh Kombinationsmikroskopie
WO2010121381A1 (en) * 2009-04-21 2010-10-28 The University Of British Columbia System and methods for detection of particles
JP5278252B2 (ja) 2009-08-31 2013-09-04 ソニー株式会社 組織切片像取得表示装置、組織切片像取得表示方法及び組織切片像取得表示プログラム
JP5338573B2 (ja) 2009-08-31 2013-11-13 ソニー株式会社 蛍光像取得方法、蛍光像取得装置及び蛍光像取得プログラム
CN102667473B (zh) 2009-10-12 2016-06-08 文塔纳医疗系统公司 用于组织的增强的病理学测定和多分析物检测的多模态对比和明场背景再现
US8314377B2 (en) * 2009-12-23 2012-11-20 Mcneil-Ppc, Inc. Device and method for detecting plaque in the oral cavity
US8236574B2 (en) * 2010-03-01 2012-08-07 Quanterix Corporation Ultra-sensitive detection of molecules or particles using beads or other capture objects
US9110025B2 (en) * 2010-03-01 2015-08-18 Quanterix Corporation Methods and systems for extending dynamic range in assays for the detection of molecules or particles
US9224031B2 (en) 2010-05-21 2015-12-29 Chemometec A/S Compact dark field light source and dark field image analysis at low magnification
WO2012019108A1 (en) * 2010-08-05 2012-02-09 Abbott Point Of Care Inc. Magnetic immunosensor with trench configuration and method of use
WO2012019104A1 (en) * 2010-08-05 2012-02-09 Abbott Point Of Care Inc. Immunoassay method and device with magnetically susceptible bead capture
DE102010044503B4 (de) * 2010-09-06 2017-11-02 Leica Microsystems (Schweiz) Ag Fluoreszenz-Operations-Stereomikroskop
JP5943927B2 (ja) * 2010-10-14 2016-07-05 メソ スケール テクノロジーズ エルエルシー アッセイデバイスにおける試薬貯蔵
US20120225475A1 (en) * 2010-11-16 2012-09-06 1087 Systems, Inc. Cytometry system with quantum cascade laser source, acoustic detector, and micro-fluidic cell handling system configured for inspection of individual cells
JP5644447B2 (ja) 2010-12-06 2014-12-24 ソニー株式会社 顕微鏡、領域判定方法、及びプログラム
US9952237B2 (en) 2011-01-28 2018-04-24 Quanterix Corporation Systems, devices, and methods for ultra-sensitive detection of molecules or particles
CN103415774B (zh) 2011-03-08 2014-09-24 独立行政法人科学技术振兴机构 颗粒封入方法、检测靶分子的方法、阵列、试剂盒及靶分子检测装置
US8681215B2 (en) * 2011-04-29 2014-03-25 ProteinSimple Method and particle analyzer for determining a broad particle size distribution
WO2012158997A1 (en) * 2011-05-18 2012-11-22 3M Innovative Properties Company Systems and methods for detecting the presence of a selected volume of material in a sample processing device
CN102243165B (zh) * 2011-06-20 2013-07-17 东南大学 光子晶体编码微球生物芯片检测装置
JP6525872B2 (ja) * 2012-08-08 2019-06-05 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 細胞中の複数のエピトープを同定するためのダイナミックレンジを高めること
US20150185152A1 (en) * 2012-08-09 2015-07-02 Life Technologies Corporation Illumination Systems
EP2904116A4 (en) * 2012-10-05 2016-05-11 California Inst Of Techn METHOD AND SYSTEMS FOR MICROFLUID RECYCLING AND ANALYSIS
US8912007B2 (en) 2013-01-22 2014-12-16 Tecan Trading Ag Optical measuring apparatus and method for the analysis of samples contained in liquid drops
US9488579B2 (en) 2013-01-22 2016-11-08 Tecan Trading Ag Optical measuring apparatus and method for the analysis of samples contained in liquid drops
US9488576B2 (en) 2013-01-22 2016-11-08 Tecan Trading Ag Optical measuring apparatus and method for the analysis of samples contained in liquid drops
US11366061B2 (en) * 2013-01-24 2022-06-21 Grace Bio-Labs, Inc. Protein microarray assay imager
KR101568573B1 (ko) * 2013-03-13 2015-11-20 고려대학교 산학협력단 혈중 희소 세포의 검출 및 계수 장치와 방법
WO2014176435A2 (en) * 2013-04-25 2014-10-30 Bergo Vladislav B Microarray compositions and methods of their use
KR101514204B1 (ko) * 2013-07-12 2015-04-23 한국전기연구원 감시림프절의 근적외선 형광 검출 장치 및 방법
CN109652295A (zh) 2014-01-31 2019-04-19 凸版印刷株式会社 生物分子分析试剂盒及生物分子分析方法
JP6383370B2 (ja) * 2014-01-31 2018-08-29 オリンパス株式会社 蛍光観察装置
FR3019900B1 (fr) 2014-04-09 2017-12-22 Bio-Rad Innovations Utilisation de particules absorbantes pour ameliorer la detection du signal dans un procede d'analyse
JP6611714B2 (ja) 2014-07-08 2019-11-27 国立研究開発法人科学技術振興機構 物質封入方法及びターゲット分子を検出する方法
US9574989B2 (en) * 2014-08-08 2017-02-21 Omnivision Technologies, Inc. Lens-free imaging system and method for detecting particles in sample deposited on image sensor
WO2016083898A1 (en) * 2014-11-28 2016-06-02 Chipcare Corporation Multiplex bead array assay
WO2016115537A2 (en) * 2015-01-15 2016-07-21 Massachusetts Institute Of Technology Systems, methods, and apparatus for in vitro single-cell identification and recovery
SG11201706367WA (en) * 2015-02-06 2017-09-28 Life Technologies Corp Systems and methods for assessing biological samples
WO2016127107A2 (en) * 2015-02-06 2016-08-11 Life Technologies Corporation Systems and methods for biological analysis
WO2016134191A1 (en) * 2015-02-18 2016-08-25 Singular Bio, Inc. Assays for single molecule detection and use thereof
US10526600B2 (en) * 2015-02-22 2020-01-07 The Board Of Trustees Of The Leland Stanford Junior University Micro-screening apparatus, process, and products
US9557270B2 (en) * 2015-03-04 2017-01-31 Ecolab Usa Inc. Multi-channel fluorometric sensor and method of using same
EP4180535A1 (en) * 2015-03-30 2023-05-17 Becton, Dickinson and Company Methods and compositions for combinatorial barcoding
KR20180063288A (ko) * 2015-10-07 2018-06-11 셀마 디아그노스틱스 에이피에스 디지털 계수를 위한 흐름 시스템 및 방법
US20170343476A1 (en) * 2016-05-31 2017-11-30 Molecular Devices, Llc Imaging system with oblique illumination
CN106226247A (zh) * 2016-07-15 2016-12-14 暨南大学 一种基于高光谱显微成像技术的细胞检测方法

Similar Documents

Publication Publication Date Title
JP2020507744A5 (enExample)
CN113049553B (zh) 用于评价生物样本的系统和方法
JP4846152B2 (ja) 低発熱光源を有する蛍光測定器
JP5026851B2 (ja) 化学発光検出装置
JP2017531168A5 (enExample)
US20200011796A1 (en) Optical module for multi-wavelength fluorescence detection
JP2014512532A5 (enExample)
JP2013500815A5 (enExample)
JP2009002955A5 (enExample)
JPWO2011145207A1 (ja) 照明光学系とこれを用いたプロジェクタ
JP2010540954A5 (enExample)
JP2014186115A5 (enExample)
US20130250248A1 (en) Fluorescent device, irradiation apparatus, and projector apparatus
US7248359B2 (en) Combining multi-spectral light from spatially separated sources
KR101210899B1 (ko) 휴대용 형광 검출 시스템
KR20030037314A (ko) 바이오 칩 분석을 위한 형광 영상 분석장치
CN100472192C (zh) 光源组件、受光组件以及使用了它们的多通道光检测装置
US20160282268A1 (en) Data processing apparatus, optical detection system, data processing method, and data processing program
JP2012156182A (ja) 蛍光物質を用いた光源装置
JP2017058367A5 (enExample)
TWI660218B (zh) 自動化螢光檢測系統
US8427637B2 (en) Optical detection system
US20130011928A1 (en) Optical detection system and/or method
EP3859309B1 (en) Optical calibration tool
WO2011142123A1 (ja) 光源、照明光学系、及び反射特性測定装置