|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
SG10201912038TA
(en)
|
2014-04-23 |
2020-02-27 |
Modernatx Inc |
Nucleic acid vaccines
|
|
US11364292B2
(en)
|
2015-07-21 |
2022-06-21 |
Modernatx, Inc. |
CHIKV RNA vaccines
|
|
EP3324979B1
(en)
|
2015-07-21 |
2022-10-12 |
ModernaTX, Inc. |
Infectious disease vaccines
|
|
WO2017020026A1
(en)
|
2015-07-30 |
2017-02-02 |
Modernatx, Inc. |
Concatemeric peptide epitopes rnas
|
|
WO2017031232A1
(en)
|
2015-08-17 |
2017-02-23 |
Modernatx, Inc. |
Methods for preparing particles and related compositions
|
|
EP3364981A4
(en)
|
2015-10-22 |
2019-08-07 |
ModernaTX, Inc. |
VACCINE AGAINST THE HUMAN CYTOMEGALOVIRUS
|
|
TW201729835A
(zh)
|
2015-10-22 |
2017-09-01 |
現代公司 |
呼吸道病毒疫苗
|
|
EP3364949A4
(en)
|
2015-10-22 |
2019-07-31 |
ModernaTX, Inc. |
CANCER VACCINES
|
|
CA3002912A1
(en)
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Nucleic acid vaccines for varicella zoster virus (vzv)
|
|
US20180289792A1
(en)
|
2015-10-22 |
2018-10-11 |
ModernaTX. Inc. |
Sexually transmitted disease vaccines
|
|
EP3364950A4
(en)
|
2015-10-22 |
2019-10-23 |
ModernaTX, Inc. |
VACCINES AGAINST TROPICAL DISEASES
|
|
HRP20220652T1
(hr)
|
2015-12-10 |
2022-06-24 |
Modernatx, Inc. |
Pripravci i postupci unosa terapijskih sredstava
|
|
US10465190B1
(en)
|
2015-12-23 |
2019-11-05 |
Modernatx, Inc. |
In vitro transcription methods and constructs
|
|
SG10201912074PA
(en)
|
2016-03-18 |
2020-02-27 |
Immune Sensor Llc |
Cyclic di-nucleotide compounds and methods of use
|
|
EP3777881A1
(en)
*
|
2016-04-22 |
2021-02-17 |
CureVac AG |
Rna encoding a tumor antigen
|
|
MA45052A
(fr)
|
2016-05-18 |
2019-03-27 |
Modernatx Inc |
Polynucléotides codant pour jagged1 pour le traitement du syndrome d'alagille
|
|
KR20230074598A
(ko)
|
2016-05-18 |
2023-05-30 |
모더나티엑스, 인크. |
릴랙신을 인코딩하는 폴리뉴클레오타이드
|
|
CN116837052A
(zh)
|
2016-09-14 |
2023-10-03 |
摩登纳特斯有限公司 |
高纯度rna组合物及其制备方法
|
|
MA46584A
(fr)
|
2016-10-21 |
2019-08-28 |
Modernatx Inc |
Vaccin contre le cytomégalovirus humain
|
|
WO2018089851A2
(en)
|
2016-11-11 |
2018-05-17 |
Modernatx, Inc. |
Influenza vaccine
|
|
WO2018107088A2
(en)
|
2016-12-08 |
2018-06-14 |
Modernatx, Inc. |
Respiratory virus nucleic acid vaccines
|
|
WO2018111967A1
(en)
|
2016-12-13 |
2018-06-21 |
Modernatx, Inc. |
Rna affinity purification
|
|
US11229668B2
(en)
*
|
2017-02-07 |
2022-01-25 |
Nantcell, Inc. |
Maximizing T-cell memory and compositions and methods therefor
|
|
WO2018151816A1
(en)
|
2017-02-16 |
2018-08-23 |
Modernatx, Inc. |
High potency immunogenic compositions
|
|
WO2018170245A1
(en)
|
2017-03-15 |
2018-09-20 |
Modernatx, Inc. |
Broad spectrum influenza virus vaccine
|
|
US11045540B2
(en)
|
2017-03-15 |
2021-06-29 |
Modernatx, Inc. |
Varicella zoster virus (VZV) vaccine
|
|
US11752206B2
(en)
|
2017-03-15 |
2023-09-12 |
Modernatx, Inc. |
Herpes simplex virus vaccine
|
|
EP3595713A4
(en)
|
2017-03-15 |
2021-01-13 |
ModernaTX, Inc. |
RESPIRATORY SYNCYTIAL VIRUS Vaccine
|
|
MA47790A
(fr)
|
2017-03-17 |
2021-05-05 |
Modernatx Inc |
Vaccins à base d'arn contre des maladies zoonotiques
|
|
WO2018187590A1
(en)
|
2017-04-05 |
2018-10-11 |
Modernatx, Inc. |
Reduction or elimination of immune responses to non-intravenous, e.g., subcutaneously administered therapeutic proteins
|
|
US11786607B2
(en)
|
2017-06-15 |
2023-10-17 |
Modernatx, Inc. |
RNA formulations
|
|
WO2019036685A1
(en)
|
2017-08-18 |
2019-02-21 |
Modernatx, Inc. |
METHODS FOR HPLC ANALYSIS
|
|
WO2019036683A1
(en)
|
2017-08-18 |
2019-02-21 |
Modernatx, Inc. |
ANALYTICAL METHODS BY HPLC
|
|
ES2983060T3
(es)
|
2017-08-18 |
2024-10-21 |
Modernatx Inc |
Variantes de ARN polimerasa
|
|
WO2019046809A1
(en)
|
2017-08-31 |
2019-03-07 |
Modernatx, Inc. |
METHODS OF MANUFACTURING LIPID NANOPARTICLES
|
|
EP3681514A4
(en)
|
2017-09-14 |
2021-07-14 |
ModernaTX, Inc. |
RNA VACZINE AGAINST ZIKA VIRUS
|
|
WO2019148101A1
(en)
|
2018-01-29 |
2019-08-01 |
Modernatx, Inc. |
Rsv rna vaccines
|
|
US12528848B2
(en)
*
|
2018-05-25 |
2026-01-20 |
The Wistar Institute Of Anatomy And Biology |
Tumor-specific neoantigens and methods of using the same
|
|
CN113365639A
(zh)
*
|
2018-06-27 |
2021-09-07 |
摩登纳特斯有限公司 |
个性化癌症疫苗表位选择
|
|
WO2020022899A1
(en)
|
2018-07-26 |
2020-01-30 |
Frame Pharmaceuticals B.V. |
Cancer vaccines for breast cancer
|
|
CA3106562A1
(en)
|
2018-07-26 |
2020-01-30 |
Frame Pharmaceuticals B.V. |
Off-the-shelf cancer vaccines
|
|
MA53650A
(fr)
|
2018-09-19 |
2021-07-28 |
Modernatx Inc |
Lipides peg et leurs utilisations
|
|
AU2019345067A1
(en)
|
2018-09-19 |
2021-04-08 |
Modernatx, Inc. |
High-purity peg lipids and uses thereof
|
|
CN113271926A
(zh)
|
2018-09-20 |
2021-08-17 |
摩登纳特斯有限公司 |
脂质纳米颗粒的制备及其施用方法
|
|
BR112021006941A2
(pt)
|
2018-10-19 |
2021-08-31 |
The Francis Crick Institute Limited |
Antígenos de câncer inovadores e métodos
|
|
CA3118947A1
(en)
*
|
2018-11-07 |
2020-05-14 |
Modernatx, Inc. |
Rna cancer vaccines
|
|
TWI852977B
(zh)
|
2019-01-10 |
2024-08-21 |
美商健生生物科技公司 |
前列腺新抗原及其用途
|
|
TW202515617A
(zh)
*
|
2019-01-14 |
2025-04-16 |
美商建南德克公司 |
用於癌症療法之rna分子
|
|
US11351242B1
(en)
|
2019-02-12 |
2022-06-07 |
Modernatx, Inc. |
HMPV/hPIV3 mRNA vaccine composition
|
|
CN113795579A
(zh)
|
2019-02-20 |
2021-12-14 |
摩登纳特斯有限公司 |
用于共转录加帽的rna聚合酶变体
|
|
US11851694B1
(en)
|
2019-02-20 |
2023-12-26 |
Modernatx, Inc. |
High fidelity in vitro transcription
|
|
CA3132975A1
(en)
|
2019-03-11 |
2020-09-17 |
Modernatx, Inc. |
Fed-batch in vitro transcription process
|
|
AU2020234003B2
(en)
*
|
2019-03-11 |
2026-02-12 |
Evaxion A/S |
Nucleic acid vaccination using neo-epitope encoding constructs
|
|
EP3938379A4
(en)
|
2019-03-15 |
2023-02-22 |
ModernaTX, Inc. |
Hiv rna vaccines
|
|
US20220152085A1
(en)
*
|
2019-03-25 |
2022-05-19 |
Ohio State Innovation Foundation |
Combination immunoregulation and uses thereof
|
|
EP3962521A1
(en)
|
2019-05-02 |
2022-03-09 |
University of Florida Research Foundation, Inc. |
Compositions for treatment of diffuse intrinsic pontine glioma
|
|
AU2020283030A1
(en)
*
|
2019-05-31 |
2021-12-23 |
Modernatx, Inc. |
Expanded T cell assay
|
|
AU2020289484A1
(en)
*
|
2019-06-07 |
2021-12-23 |
Emory University |
KRAS G12V mutant binds to JAK1, inhibitors, pharmaceutical compositions, and methods related thereto
|
|
CN110172480B
(zh)
*
|
2019-06-11 |
2020-01-07 |
北京鼎成肽源生物技术有限公司 |
双抗原表位融合基因重组慢病毒载体、抗原提呈细胞和ctl细胞及其构建方法和应用
|
|
CN110172089B
(zh)
*
|
2019-06-11 |
2020-01-07 |
北京鼎成肽源生物技术有限公司 |
一种kras突变多抗原组合、靶向kras突变肿瘤ctl及其应用
|
|
JP2022546417A
(ja)
*
|
2019-08-29 |
2022-11-04 |
チューリッヒ大学 |
最小ｍＲＮＡおよびその使用
|
|
KR20220115569A
(ko)
|
2019-11-18 |
2022-08-17 |
얀센 바이오테크 인코포레이티드 |
돌연변이 calr 및 jak2에 기반한 백신 및 이의 용도
|
|
US20230002799A1
(en)
*
|
2019-12-11 |
2023-01-05 |
Vanderbilt University |
Methods of synthesizing mrna and functional proteins from synthetic double stranded dna
|
|
WO2021155267A2
(en)
*
|
2020-01-30 |
2021-08-05 |
Modernatx, Inc. |
Mrnas encoding metabolic reprogramming polypeptides and uses thereof
|
|
MX2022009391A
(es)
*
|
2020-01-31 |
2022-09-26 |
Genentech Inc |
Metodos para inducir linfocitos t especificos para neoepitopo con un antagonista de union al eje de pd-1 y una vacuna de arn.
|
|
EP4099988A4
(en)
*
|
2020-02-05 |
2024-03-13 |
University of Florida Research Foundation, Incorporated |
Rna-loaded nanoparticles and use thereof for the treatment of cancer
|
|
IL296234A
(en)
*
|
2020-03-11 |
2022-11-01 |
Advansix Resins & Chemicals Llc |
Surfactants for healthcare products
|
|
AU2021236069B9
(en)
|
2020-03-11 |
2024-02-01 |
Advansix Resins & Chemicals Llc |
Surfactants for oil and gas production
|
|
AU2021236067C1
(en)
|
2020-03-11 |
2025-07-17 |
Advansix Resins & Chemicals Llc |
Surfactants for agricultural products
|
|
JP2023522193A
(ja)
*
|
2020-04-17 |
2023-05-29 |
ザ フランシス クリック インスティチュート リミティッド |
抗原プール
|
|
EP3901261A1
(en)
|
2020-04-22 |
2021-10-27 |
BioNTech RNA Pharmaceuticals GmbH |
Coronavirus vaccine
|
|
US11130787B2
(en)
*
|
2020-06-11 |
2021-09-28 |
MBF Therapeutics, Inc. |
Alphaherpesvirus glycoprotein d-encoding nucleic acid constructs and methods
|
|
KR20230034333A
(ko)
|
2020-07-02 |
2023-03-09 |
라이프 테크놀로지스 코포레이션 |
트리뉴클레오티드 캡 유사체, 제조 및 이의 용도
|
|
US12295997B2
(en)
|
2020-07-06 |
2025-05-13 |
Janssen Biotech, Inc. |
Prostate neoantigens and their uses
|
|
CN116322751A
(zh)
*
|
2020-08-04 |
2023-06-23 |
蛋白科技先锋 |
包含能够动力学控制的佐剂的mRNA疫苗
|
|
WO2022036159A2
(en)
|
2020-08-12 |
2022-02-17 |
Actym Therapeutics, Inc. |
Immunostimulatory bacteria-based vaccines, therapeutics, and rna delivery platforms
|
|
US11406703B2
(en)
|
2020-08-25 |
2022-08-09 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
|
KR102366490B1
(ko)
|
2020-10-20 |
2022-02-23 |
에스티팜 주식회사 |
5'-캡핑된 rna 합성용 올리고뉴클레오티드
|
|
EP4232036A4
(en)
*
|
2020-10-22 |
2024-10-30 |
The Regents of University of California |
MONOAMINE OXIDASE BLOCKADE THERAPY FOR CANCER TREATMENT BY REGULATION OF TUMOR-ASSOCIATED MACROPHAGES (TAMs)
|
|
WO2022120560A1
(zh)
*
|
2020-12-08 |
2022-06-16 |
深圳市瑞吉生物科技有限公司 |
一种mRNA剂型的免疫抑制剂及其在制备肿瘤治疗药物中的应用
|
|
WO2022140278A1
(en)
*
|
2020-12-21 |
2022-06-30 |
University Of Florida Research Foundation, Inc. |
Multilamellar rna nanoparticle vaccine against cancer
|
|
CN114717229B
(zh)
*
|
2021-01-05 |
2024-09-10 |
麦塞拿治疗(香港)有限公司 |
治疗性mRNA的无细胞和无载体体外RNA转录方法和核酸分子
|
|
US12329811B2
(en)
|
2021-01-11 |
2025-06-17 |
Modernatx, Inc. |
Seasonal RNA influenza virus vaccines
|
|
AU2022221309A1
(en)
*
|
2021-02-09 |
2023-08-24 |
Virginia Commonwealth University |
Mini circular rna therapeutics and vaccines and methods of use thereof
|
|
US11524023B2
(en)
|
2021-02-19 |
2022-12-13 |
Modernatx, Inc. |
Lipid nanoparticle compositions and methods of formulating the same
|
|
WO2022204491A1
(en)
*
|
2021-03-26 |
2022-09-29 |
Modernatx, Inc. |
Pertussis vaccine
|
|
NL2028681B1
(en)
*
|
2021-04-02 |
2022-10-17 |
Nutcracker Therapeutics Inc |
Materials and methods for generating antigen-specific t cells and treating diseases
|
|
CN113186285B
(zh)
*
|
2021-05-10 |
2022-05-24 |
深圳市展行生物有限公司 |
一种辅助诊断胃癌的方法及其使用的miRNA组合
|
|
US20220363937A1
(en)
|
2021-05-14 |
2022-11-17 |
Armstrong World Industries, Inc. |
Stabilization of antimicrobial coatings
|
|
CN113577258B
(zh)
*
|
2021-07-31 |
2024-04-16 |
山东兴瑞生物科技有限公司 |
一种双靶点mRNA疫苗及其制备方法
|
|
CN115703714B
(zh)
*
|
2021-08-13 |
2025-06-10 |
广州谷森制药有限公司 |
阳离子脂质化合物
|
|
WO2023030635A1
(en)
*
|
2021-09-02 |
2023-03-09 |
BioNTech SE |
Potency assay for therapeutic potential of coding nucleic acid
|
|
JP2024533501A
(ja)
|
2021-09-13 |
2024-09-12 |
オンコディーエヌエー |
患者の腫瘍の個別化された新生抗原を生成する方法
|
|
EP4147712A1
(en)
|
2021-09-13 |
2023-03-15 |
OncoDNA |
Method to generate a double-stranded dna pool encoding neoantigens of a tumor of a patient
|
|
EP4147713A1
(en)
*
|
2021-09-13 |
2023-03-15 |
OncoDNA |
A rna vaccine comprising an rna pool generated from a double-stranded dna pool
|
|
CA3235418A1
(en)
|
2021-11-09 |
2023-05-19 |
Actym Therapeutics, Inc. |
Immunostimulatory bacteria for converting macrophages into a phenotype amenable to treatment, and companion diagnostic for identifying subjects for treatment
|
|
US12186387B2
(en)
|
2021-11-29 |
2025-01-07 |
BioNTech SE |
Coronavirus vaccine
|
|
US12529047B1
(en)
|
2021-12-21 |
2026-01-20 |
Modernatx, Inc. |
mRNA quantification methods
|
|
CN116376942A
(zh)
*
|
2021-12-31 |
2023-07-04 |
广州国家实验室 |
mRNA疫苗
|
|
WO2024002985A1
(en)
|
2022-06-26 |
2024-01-04 |
BioNTech SE |
Coronavirus vaccine
|
|
WO2024026490A1
(en)
*
|
2022-07-28 |
2024-02-01 |
Sqz Biotechnologies Company |
Polynucleotides encoding linked antigens and uses thereof
|
|
CN115992152A
(zh)
*
|
2022-09-22 |
2023-04-21 |
浙江大学医学院附属第一医院 |
一种用于乙型肝炎病毒治疗性mRNA疫苗及其制备方法与应用
|
|
JPWO2024075851A1
(https=)
*
|
2022-10-07 |
2024-04-11 |
|
|
|
EP4604981A2
(en)
*
|
2022-10-19 |
2025-08-27 |
KaliVir Immunotherapeutics, Inc. |
Nucleic acids encoding soluble pd-1 and il-12 and uses thereof
|
|
JP2026502789A
(ja)
*
|
2022-10-31 |
2026-01-27 |
グリットストーン バイオ インコーポレイテッド |
組み合わせパネルのセルフリーｄｎａモニタリング
|
|
EP4612301A1
(en)
*
|
2022-11-03 |
2025-09-10 |
ModernaTX, Inc. |
Chemical stability of mrna
|
|
EP4364752A1
(en)
|
2022-11-07 |
2024-05-08 |
OncoDNA |
Improved vaccine
|
|
CN116970614A
(zh)
*
|
2022-12-29 |
2023-10-31 |
达冕疫苗(广州)有限公司 |
编码ny-eso-1的核糖核酸疫苗的组合物和方法
|
|
EP4651888A1
(en)
*
|
2023-01-17 |
2025-11-26 |
The University Of Hong Kong |
Cancer immunotherapy by delivery of mrna
|
|
CN119055671A
(zh)
*
|
2023-05-23 |
2024-12-03 |
源生生物科技(青岛)有限责任公司 |
包含miRNA的活性成分及其应用
|
|
WO2025054383A1
(en)
*
|
2023-09-06 |
2025-03-13 |
Modernatx, Inc. |
Chemical stability of mrna
|
|
WO2025080869A1
(en)
*
|
2023-10-11 |
2025-04-17 |
The Regents Of The University Of California |
Pancreatic cancer immunotherapy using cationic lipid and polymer nanocarriers for co-delivery of kras neoantigens and sting and/or other immunomodulators to boost the cancer immunity cycle and treat liver metastasis
|
|
WO2025117816A1
(en)
*
|
2023-12-01 |
2025-06-05 |
Recode Therapeutics, Inc. |
Lipid nanoparticle compositions and uses thereof
|
|
WO2025153053A1
(en)
*
|
2024-01-17 |
2025-07-24 |
Abogen Biosciences (Shanghai) Co., Ltd. |
Composition and methods for inducing antigen specific immunity against kras mutant cells
|
|
WO2025158069A1
(en)
*
|
2024-01-25 |
2025-07-31 |
Rheinische Friedrich-Wilhelms-Universität Bonn |
CONSTRUCT COMPRISING mRNA-STRAND AND RETINOIC ACID-INDUCIBLE GENE I (RIG-I)-LIGAND(S), PHARMACEUTICAL COMPOSITION AND KIT COMPRISING THE SAME
|
|
CN118389553A
(zh)
*
|
2024-03-01 |
2024-07-26 |
中国科学技术大学 |
免疫增效rna分子及其组合物、疫苗与试剂盒
|
|
CN117883558B
(zh)
*
|
2024-03-15 |
2024-06-14 |
山东兴瑞生物科技有限公司 |
靶向肝肿瘤个性化mRNA疫苗的制备方法
|
|
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