|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
US4309989A
(en)
|
1976-02-09 |
1982-01-12 |
The Curators Of The University Of Missouri |
Topical application of medication by ultrasound with coupling agent
|
|
FR2374910A1
(fr)
|
1976-10-23 |
1978-07-21 |
Choay Sa |
Preparation a base d'heparine, comprenant des liposomes, procede pour l'obtenir et medicaments contenant de telles preparations
|
|
US4554101A
(en)
|
1981-01-09 |
1985-11-19 |
New York Blood Center, Inc. |
Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
|
|
US4656134A
(en)
|
1982-01-11 |
1987-04-07 |
Board Of Trustees Of Leland Stanford Jr. University |
Gene amplification in eukaryotic cells
|
|
US5168062A
(en)
|
1985-01-30 |
1992-12-01 |
University Of Iowa Research Foundation |
Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
|
|
US4965188A
(en)
|
1986-08-22 |
1990-10-23 |
Cetus Corporation |
Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
|
|
US4683195A
(en)
|
1986-01-30 |
1987-07-28 |
Cetus Corporation |
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US4766067A
(en)
|
1985-05-31 |
1988-08-23 |
President And Fellows Of Harvard College |
Gene amplification
|
|
US5576195A
(en)
|
1985-11-01 |
1996-11-19 |
Xoma Corporation |
Vectors with pectate lyase signal sequence
|
|
US5618920A
(en)
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
|
US4800159A
(en)
|
1986-02-07 |
1989-01-24 |
Cetus Corporation |
Process for amplifying, detecting, and/or cloning nucleic acid sequences
|
|
US4767402A
(en)
|
1986-07-08 |
1988-08-30 |
Massachusetts Institute Of Technology |
Ultrasound enhancement of transdermal drug delivery
|
|
AU610083B2
(en)
|
1986-08-18 |
1991-05-16 |
Clinical Technologies Associates, Inc. |
Delivery systems for pharmacological agents
|
|
US4889818A
(en)
|
1986-08-22 |
1989-12-26 |
Cetus Corporation |
Purified thermostable enzyme
|
|
US5260203A
(en)
|
1986-09-02 |
1993-11-09 |
Enzon, Inc. |
Single polypeptide chain binding molecules
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
US4704692A
(en)
|
1986-09-02 |
1987-11-03 |
Ladner Robert C |
Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
|
|
US4921794A
(en)
|
1987-01-14 |
1990-05-01 |
President And Fellows Of Harvard College |
T7 DNA polymerase
|
|
US4795699A
(en)
|
1987-01-14 |
1989-01-03 |
President And Fellows Of Harvard College |
T7 DNA polymerase
|
|
US4939666A
(en)
|
1987-09-02 |
1990-07-03 |
Genex Corporation |
Incremental macromolecule construction methods
|
|
US5130238A
(en)
|
1988-06-24 |
1992-07-14 |
Cangene Corporation |
Enhanced nucleic acid amplification process
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
US5091310A
(en)
|
1988-09-23 |
1992-02-25 |
Cetus Corporation |
Structure-independent dna amplification by the polymerase chain reaction
|
|
US5066584A
(en)
|
1988-09-23 |
1991-11-19 |
Cetus Corporation |
Methods for generating single stranded dna by the polymerase chain reaction
|
|
US5142033A
(en)
|
1988-09-23 |
1992-08-25 |
Hoffmann-La Roche Inc. |
Structure-independent DNA amplification by the polymerase chain reaction
|
|
US4994370A
(en)
|
1989-01-03 |
1991-02-19 |
The United States Of America As Represented By The Department Of Health And Human Services |
DNA amplification technique
|
|
US5266491A
(en)
|
1989-03-14 |
1993-11-30 |
Mochida Pharmaceutical Co., Ltd. |
DNA fragment and expression plasmid containing the DNA fragment
|
|
AU638762B2
(en)
|
1989-10-05 |
1993-07-08 |
Optein Inc |
Cell-free synthesis and isolation of novel genes and polypeptides
|
|
US5580575A
(en)
|
1989-12-22 |
1996-12-03 |
Imarx Pharmaceutical Corp. |
Therapeutic drug delivery systems
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
DK0600866T3
(da)
|
1990-06-01 |
1998-03-09 |
Chiron Corp |
Præparater og fremgangsmåder til identifikation af biologisk aktive molekyler
|
|
US5723286A
(en)
|
1990-06-20 |
1998-03-03 |
Affymax Technologies N.V. |
Peptide library and screening systems
|
|
US5580734A
(en)
|
1990-07-13 |
1996-12-03 |
Transkaryotic Therapies, Inc. |
Method of producing a physical map contigous DNA sequences
|
|
WO1992005258A1
(en)
|
1990-09-20 |
1992-04-02 |
La Trobe University |
Gene encoding barley enzyme
|
|
CA2095633C
(en)
|
1990-12-03 |
2003-02-04 |
Lisa J. Garrard |
Enrichment method for variant proteins with altered binding properties
|
|
JPH06508022A
(ja)
|
1991-02-21 |
1994-09-14 |
ギリアド サイエンシズ,インコーポレイテッド |
生体分子に特異的なアプタマーおよび生産方法
|
|
ATE240740T1
(de)
|
1991-03-15 |
2003-06-15 |
Amgen Inc |
Pegylation von polypeptiden
|
|
US5270170A
(en)
|
1991-10-16 |
1993-12-14 |
Affymax Technologies N.V. |
Peptide library and screening method
|
|
US5733761A
(en)
|
1991-11-05 |
1998-03-31 |
Transkaryotic Therapies, Inc. |
Protein production and protein delivery
|
|
US5641670A
(en)
|
1991-11-05 |
1997-06-24 |
Transkaryotic Therapies, Inc. |
Protein production and protein delivery
|
|
PT1024191E
(pt)
|
1991-12-02 |
2008-12-22 |
Medical Res Council |
Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
|
|
US5643252A
(en)
|
1992-10-28 |
1997-07-01 |
Venisect, Inc. |
Laser perforator
|
|
WO1994012520A1
(en)
|
1992-11-20 |
1994-06-09 |
Enzon, Inc. |
Linker for linked fusion polypeptides
|
|
US5849695A
(en)
|
1993-01-13 |
1998-12-15 |
The Regents Of The University Of California |
Parathyroid hormone analogues useful for treatment of osteoporosis and disorders of calcium meatabolism in mammals
|
|
EP0804561B1
(en)
|
1993-02-12 |
2009-12-30 |
The Board Of Trustees Of The Leland Stanford Junior University |
Regulated transcription of targeted genes and other biological events
|
|
US5514670A
(en)
|
1993-08-13 |
1996-05-07 |
Pharmos Corporation |
Submicron emulsions for delivery of peptides
|
|
US5814599A
(en)
|
1995-08-04 |
1998-09-29 |
Massachusetts Insitiute Of Technology |
Transdermal delivery of encapsulated drugs
|
|
US5763733A
(en)
|
1994-10-13 |
1998-06-09 |
Enzon, Inc. |
Antigen-binding fusion proteins
|
|
US5549551A
(en)
|
1994-12-22 |
1996-08-27 |
Advanced Cardiovascular Systems, Inc. |
Adjustable length balloon catheter
|
|
US5656730A
(en)
|
1995-04-07 |
1997-08-12 |
Enzon, Inc. |
Stabilized monomeric protein compositions
|
|
US5730723A
(en)
|
1995-10-10 |
1998-03-24 |
Visionary Medical Products Corporation, Inc. |
Gas pressured needle-less injection device and method
|
|
US6218185B1
(en)
|
1996-04-19 |
2001-04-17 |
The United States Of America As Represented By The Secretary Of Agriculture |
Piggybac transposon-based genetic transformation system for insects
|
|
US5827729A
(en)
|
1996-04-23 |
1998-10-27 |
Advanced Tissue Sciences |
Diffusion gradient bioreactor and extracorporeal liver device using a three-dimensional liver tissue
|
|
US5879681A
(en)
|
1997-02-07 |
1999-03-09 |
Emisphere Technolgies Inc. |
Compounds and compositions for delivering active agents
|
|
IL120943A
(en)
|
1997-05-29 |
2004-03-28 |
Univ Ben Gurion |
A system for administering drugs through the skin
|
|
US6309663B1
(en)
|
1999-08-17 |
2001-10-30 |
Lipocine Inc. |
Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents
|
|
US6835394B1
(en)
|
1999-12-14 |
2004-12-28 |
The Trustees Of The University Of Pennsylvania |
Polymersomes and related encapsulating membranes
|
|
US6962810B2
(en)
|
2000-10-31 |
2005-11-08 |
University Of Notre Dame Du Lac |
Methods and compositions for transposition using minimal segments of the eukaryotic transformation vector piggyBac
|
|
US7088011B2
(en)
|
2003-11-21 |
2006-08-08 |
Smith Raymond W |
Motor-generator system with a current control feedback loop
|
|
EP2160461B1
(en)
|
2007-07-04 |
2012-08-08 |
Max-Delbrück-Centrum für Molekulare Medizin (MDC) |
Hyperactive variants of the transposase protein of the transposon system sleeping beauty
|
|
US8399643B2
(en)
|
2009-02-26 |
2013-03-19 |
Transposagen Biopharmaceuticals, Inc. |
Nucleic acids encoding hyperactive PiggyBac transposases
|
|
US8808748B2
(en)
|
2010-04-20 |
2014-08-19 |
Vindico NanoBio Technology Inc. |
Biodegradable nanoparticles as novel hemoglobin-based oxygen carriers and methods of using the same
|
|
US20140363496A1
(en)
|
2011-01-07 |
2014-12-11 |
Vindico NanoBio Technology Inc. |
Compositions and Methods for Inducing Nanoparticle-mediated Microvascular Embolization of Tumors
|
|
WO2015116753A1
(en)
*
|
2014-01-29 |
2015-08-06 |
Dana-Farber Cancer Institute, Inc. |
Antibodies against the muc1-c/extracellular domain (muc1-c/ecd)
|
|
US10344285B2
(en)
|
2014-04-09 |
2019-07-09 |
Dna2.0, Inc. |
DNA vectors, transposons and transposases for eukaryotic genome modification
|
|
CA2952618A1
(en)
|
2014-06-17 |
2015-12-23 |
Poseida Therapeutics, Inc. |
Methods and compositions for in vivo non-covalent linking
|
|
US20170107541A1
(en)
|
2014-06-17 |
2017-04-20 |
Poseida Therapeutics, Inc. |
A method for directing proteins to specific loci in the genome and uses thereof
|
|
US11473082B2
(en)
|
2015-06-17 |
2022-10-18 |
Poseida Therapeutics, Inc. |
Compositions and methods for directing proteins to specific loci in the genome
|
|
US20170000743A1
(en)
|
2015-07-02 |
2017-01-05 |
Vindico NanoBio Technology Inc. |
Compositions and Methods for Delivery of Gene Editing Tools Using Polymeric Vesicles
|
|
US10456452B2
(en)
|
2015-07-02 |
2019-10-29 |
Poseida Therapeutics, Inc. |
Compositions and methods for improved encapsulation of functional proteins in polymeric vesicles
|
|
US11213594B2
(en)
|
2016-04-29 |
2022-01-04 |
Poseida Therapeutics, Inc. |
Poly(histidine)-based micelles for complexation and delivery of proteins and nucleic acids
|
|
WO2018014039A1
(en)
*
|
2016-07-15 |
2018-01-18 |
Poseida Therapeutics, Inc. |
Chimeric antigen receptors (cars) specific for muc1 and methods for their use
|
|
US10617773B2
(en)
*
|
2016-08-05 |
2020-04-14 |
Dana-Farber Cancer Institute, Inc. |
Antibodies against the MUC1-C/extracellular domain (MUC1-C/ECD)
|
|
ES3051391T3
(en)
|
2016-10-06 |
2025-12-29 |
Poseida Therapeutics Inc |
Inducible caspases and methods for use
|
|
GB201709203D0
(en)
*
|
2017-06-09 |
2017-07-26 |
Autolus Ltd |
Antigen-binding domain
|
|
WO2018231759A1
(en)
*
|
2017-06-12 |
2018-12-20 |
Obsidian Therapeutics, Inc. |
Pde5 compositions and methods for immunotherapy
|
|
EP3680280A4
(en)
|
2017-09-05 |
2021-06-02 |
Toray Industries, Inc. |
FIBER REINFORCED THERMOPLASTIC RESIN MOLDINGS
|
|
US10329543B2
(en)
|
2017-10-23 |
2019-06-25 |
Poseida Therapeutics, Inc. |
Modified stem cell memory T cells, methods of making and methods of using same
|
|
WO2019126589A1
(en)
|
2017-12-20 |
2019-06-27 |
Poseida Therapeutics, Inc. |
Micelles for complexation and delivery of proteins and nucleic acids
|
|
TWI908706B
(zh)
|
2018-03-07 |
2025-12-21 |
美商波西達治療公司 |
CARTyrin組成物和使用方法
|
|
WO2019225667A1
(ja)
|
2018-05-23 |
2019-11-28 |
一般財団法人阪大微生物病研究会 |
リン酸アルミニウム化合物
|
|
EP3983447A4
(en)
*
|
2019-06-14 |
2023-06-28 |
Dana-Farber Cancer Institute, Inc. |
Antibodies against muc1 and methods of use thereof
|