JP2021534784A5 - - Google Patents

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Publication number
JP2021534784A5
JP2021534784A5 JP2021510693A JP2021510693A JP2021534784A5 JP 2021534784 A5 JP2021534784 A5 JP 2021534784A5 JP 2021510693 A JP2021510693 A JP 2021510693A JP 2021510693 A JP2021510693 A JP 2021510693A JP 2021534784 A5 JP2021534784 A5 JP 2021534784A5
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JP
Japan
Prior art keywords
isolated polynucleotide
amino acid
cells
seq
sequence identity
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JP2021510693A
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English (en)
Japanese (ja)
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JP2021534784A (ja
JP7627080B2 (ja
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Priority claimed from PCT/US2019/048814 external-priority patent/WO2020047257A1/en
Publication of JP2021534784A publication Critical patent/JP2021534784A/ja
Publication of JP2021534784A5 publication Critical patent/JP2021534784A5/ja
Priority to JP2025009061A priority Critical patent/JP2025066785A/ja
Application granted granted Critical
Publication of JP7627080B2 publication Critical patent/JP7627080B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021510693A 2018-08-31 2019-08-29 Ｂ７ｈ３キメラ抗原受容体を含む方法および組成物 Active JP7627080B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025009061A JP2025066785A (ja) 2018-08-31 2025-01-22 Ｂ７ｈ３キメラ抗原受容体を含む方法および組成物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862725599P 2018-08-31 2018-08-31
US62/725,599 2018-08-31
PCT/US2019/048814 WO2020047257A1 (en) 2018-08-31 2019-08-29 Methods and compositions comprising b7h3 chimeric antigen receptors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025009061A Division JP2025066785A (ja) 2018-08-31 2025-01-22 Ｂ７ｈ３キメラ抗原受容体を含む方法および組成物

Publications (3)

Publication Number Publication Date
JP2021534784A JP2021534784A (ja) 2021-12-16
JP2021534784A5 true JP2021534784A5 (https=) 2023-03-20
JP7627080B2 JP7627080B2 (ja) 2025-02-05

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ID=69643750

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JP2021510693A Active JP7627080B2 (ja) 2018-08-31 2019-08-29 Ｂ７ｈ３キメラ抗原受容体を含む方法および組成物
JP2025009061A Pending JP2025066785A (ja) 2018-08-31 2025-01-22 Ｂ７ｈ３キメラ抗原受容体を含む方法および組成物

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JP2025009061A Pending JP2025066785A (ja) 2018-08-31 2025-01-22 Ｂ７ｈ３キメラ抗原受容体を含む方法および組成物

Country Status (8)

Country Link
US (2) US12173071B2 (https=)
EP (1) EP3844191A4 (https=)
JP (2) JP7627080B2 (https=)
CN (1) CN113039206A (https=)
AU (1) AU2019333149A1 (https=)
CA (1) CA3110858A1 (https=)
IL (1) IL281129A (https=)
WO (1) WO2020047257A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4257154A4 (en) 2021-02-09 2026-04-22 Medilink Therapeutics Suzhou Co Ltd CONJUGATED WITH A BIOACTIVE SUBSTANCE, ITS PREPARATION PROCESS AND ITS USE
CN118647408A (zh) 2022-02-16 2024-09-13 苏州宜联生物医药有限公司 抗体-艾日布林或其衍生物的偶联物、其中间体、制备方法、药物组合物和用途
CN119212733A (zh) 2022-05-18 2024-12-27 苏州宜联生物医药有限公司 包含蛋白降解剂类生物活性化合物的抗体药物偶联物及其制备方法和用途
CN117986362A (zh) * 2022-11-04 2024-05-07 茂行制药(苏州)有限公司 靶向b7h3的通用型car-t细胞及其制备方法和应用
WO2024106941A1 (ko) * 2022-11-15 2024-05-23 주식회사 셀랩메드 B7-h3 키메라 항원 수용체 및 이의 용도
KR20260017010A (ko) * 2023-04-24 2026-02-04 엘피스 바이오파마슈티컬즈 장갑 항-b7h3 car-t 세포 및 암 치료에 있어서의 그 용도
WO2025235801A1 (en) 2024-05-08 2025-11-13 City Of Hope Antibodies targeted to osteopontin and uses thereof for reducing resistance of solid tumors immune cell therapy

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5827642A (en) 1994-08-31 1998-10-27 Fred Hutchinson Cancer Research Center Rapid expansion method ("REM") for in vitro propagation of T lymphocytes
US10155038B2 (en) * 2007-02-02 2018-12-18 Yale University Cells prepared by transient transfection and methods of use thereof
TR201904484T4 (tr) 2009-11-03 2019-05-21 Hope City Transdüse T hücre seçimine yönelik kesik epiderimal büyüme faktörü reseptörü (EGFRt).
EP2542256B1 (en) * 2010-03-04 2019-05-22 MacroGenics, Inc. Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
PH12012501751A1 (en) * 2010-03-04 2012-11-12 Macrogenics Inc Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
BR122020002986A8 (pt) * 2012-08-20 2023-04-18 Seattle Childrens Hospital Dba Seattle Childrens Res Inst Método e composições para imunoterapia celular
US9790282B2 (en) * 2013-03-25 2017-10-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-CD276 polypeptides, proteins, and chimeric antigen receptors
CN105873952A (zh) * 2013-10-31 2016-08-17 弗莱德哈钦森癌症研究中心 经修饰的造血干细胞/祖细胞和非t效应细胞及其用途
US10611837B2 (en) 2014-04-10 2020-04-07 Seattle Children's Hospital Transgene genetic tags and methods of use
EP3288569A4 (en) * 2015-04-29 2018-12-19 Fred Hutchinson Cancer Research Center Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
US10562952B2 (en) 2015-09-10 2020-02-18 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-CD276 chimeric antigen receptors
KR20230148844A (ko) * 2016-03-29 2023-10-25 유니버시티 오브 써던 캘리포니아 암을 표적하는 키메라 항원 수용체
US10188749B2 (en) * 2016-04-14 2019-01-29 Fred Hutchinson Cancer Research Center Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
EP3448874A4 (en) * 2016-04-29 2020-04-22 Voyager Therapeutics, Inc. COMPOSITIONS FOR TREATING A DISEASE
US11771718B2 (en) * 2017-10-18 2023-10-03 Precigen, Inc. Polypeptide compositions comprising spacers
WO2020010239A1 (en) * 2018-07-06 2020-01-09 The Board Of Trustees Of The Leland Stanford Junior University Chimeric antigen receptor polypeptides and methods of using same

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