|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
DK4023249T3
(da)
|
2014-04-23 |
2025-01-13 |
Modernatx Inc |
Nukleinsyrevacciner
|
|
EP4218805A1
(en)
|
2015-07-21 |
2023-08-02 |
ModernaTX, Inc. |
Infectious disease vaccines
|
|
US11364292B2
(en)
|
2015-07-21 |
2022-06-21 |
Modernatx, Inc. |
CHIKV RNA vaccines
|
|
US12150980B2
(en)
|
2015-07-30 |
2024-11-26 |
Modernatx, Inc. |
Concatemeric peptide epitope RNAs
|
|
US11564893B2
(en)
|
2015-08-17 |
2023-01-31 |
Modernatx, Inc. |
Methods for preparing particles and related compositions
|
|
AU2016342376A1
(en)
|
2015-10-22 |
2018-06-07 |
Modernatx, Inc. |
Sexually transmitted disease vaccines
|
|
MA46316A
(fr)
|
2015-10-22 |
2021-03-24 |
Modernatx Inc |
Vaccin contre le cytomégalovirus humain
|
|
CN117731769A
(zh)
|
2015-10-22 |
2024-03-22 |
摩登纳特斯有限公司 |
用于水痘带状疱疹病毒(vzv)的核酸疫苗
|
|
MA52645B1
(fr)
|
2015-10-22 |
2022-06-30 |
Modernatx Inc |
Vaccins contre le virus respiratoire
|
|
WO2017070624A1
(en)
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Tropical disease vaccines
|
|
MD3386484T2
(ro)
|
2015-12-10 |
2022-11-30 |
Modernatx Inc |
Compoziții și metode de livrare a unor agenți terapeutici
|
|
US10465190B1
(en)
|
2015-12-23 |
2019-11-05 |
Modernatx, Inc. |
In vitro transcription methods and constructs
|
|
NZ746112A
(en)
|
2016-03-18 |
2023-01-27 |
Immune Sensor Llc |
Cyclic di-nucleotide compounds and methods of use
|
|
EP4487869A3
(en)
*
|
2016-04-22 |
2025-07-30 |
CureVac SE |
Rna encoding a tumor antigen
|
|
WO2017201342A1
(en)
|
2016-05-18 |
2017-11-23 |
Modernatx, Inc. |
Polynucleotides encoding jagged1 for the treatment of alagille syndrome
|
|
EP3458034A4
(en)
|
2016-05-18 |
2020-01-01 |
ModernaTX, Inc. |
POLYNUCLEOTIDES ENCODING RELAXIN
|
|
CN109937253B
(zh)
|
2016-09-14 |
2023-06-30 |
摩登纳特斯有限公司 |
高纯度rna组合物及其制备方法
|
|
WO2018075980A1
(en)
|
2016-10-21 |
2018-04-26 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
|
US10925958B2
(en)
|
2016-11-11 |
2021-02-23 |
Modernatx, Inc. |
Influenza vaccine
|
|
MA50335A
(fr)
|
2016-12-08 |
2020-08-19 |
Modernatx Inc |
Vaccins à acide nucléique contre des virus respiratoires
|
|
US11384352B2
(en)
|
2016-12-13 |
2022-07-12 |
Modernatx, Inc. |
RNA affinity purification
|
|
EP3579885A4
(en)
*
|
2017-02-07 |
2020-12-16 |
Nantcell, Inc. |
MAXIMIZING T CELL MEMORY, COMPOSITIONS AND RELATED METHODS
|
|
MA47515A
(fr)
|
2017-02-16 |
2019-12-25 |
Modernatx Inc |
Compositions immunogènes très puissantes
|
|
EP3595713A4
(en)
|
2017-03-15 |
2021-01-13 |
ModernaTX, Inc. |
Respiratory syncytial virus vaccine
|
|
WO2018170270A1
(en)
|
2017-03-15 |
2018-09-20 |
Modernatx, Inc. |
Varicella zoster virus (vzv) vaccine
|
|
US11576961B2
(en)
|
2017-03-15 |
2023-02-14 |
Modernatx, Inc. |
Broad spectrum influenza virus vaccine
|
|
US11752206B2
(en)
|
2017-03-15 |
2023-09-12 |
Modernatx, Inc. |
Herpes simplex virus vaccine
|
|
US20200030432A1
(en)
|
2017-03-17 |
2020-01-30 |
Modernatx, Inc. |
Zoonotic disease rna vaccines
|
|
EP3607074A4
(en)
|
2017-04-05 |
2021-07-07 |
Modernatx, Inc. |
REDUCTION OR ELIMINATION OF IMMUNE RESPONSES TO NON-INTRAVENOUS THERAPEUTIC PROTEINS, FOR EXAMPLE SUBCUTANEOUSLY
|
|
US11786607B2
(en)
|
2017-06-15 |
2023-10-17 |
Modernatx, Inc. |
RNA formulations
|
|
US11866696B2
(en)
|
2017-08-18 |
2024-01-09 |
Modernatx, Inc. |
Analytical HPLC methods
|
|
US11912982B2
(en)
|
2017-08-18 |
2024-02-27 |
Modernatx, Inc. |
Methods for HPLC analysis
|
|
WO2019036682A1
(en)
|
2017-08-18 |
2019-02-21 |
Modernatx, Inc. |
RNA VARIANTS POLYMERASE
|
|
MX2020002348A
(es)
|
2017-08-31 |
2020-10-08 |
Modernatx Inc |
Métodos de elaboración de nanopartículas lipídicas.
|
|
MA50253A
(fr)
|
2017-09-14 |
2020-07-22 |
Modernatx Inc |
Vaccins à arn contre le virus zika
|
|
US11911453B2
(en)
|
2018-01-29 |
2024-02-27 |
Modernatx, Inc. |
RSV RNA vaccines
|
|
EP3813848A4
(en)
*
|
2018-06-27 |
2022-07-20 |
ModernaTX, Inc. |
Personalized cancer vaccine epitope selection
|
|
EP3826669A2
(en)
|
2018-07-26 |
2021-06-02 |
Frame Pharmaceuticals B.V. |
Off-the-shelf cancer vaccines
|
|
EP4509118A3
(en)
|
2018-09-19 |
2025-05-14 |
ModernaTX, Inc. |
High-purity peg lipids and uses thereof
|
|
CA3113025A1
(en)
|
2018-09-19 |
2020-03-26 |
Modernatx, Inc. |
Peg lipids and uses thereof
|
|
US12090235B2
(en)
|
2018-09-20 |
2024-09-17 |
Modernatx, Inc. |
Preparation of lipid nanoparticles and methods of administration thereof
|
|
BR112021006941A2
(pt)
|
2018-10-19 |
2021-08-31 |
The Francis Crick Institute Limited |
Antígenos de câncer inovadores e métodos
|
|
JP2022506839A
(ja)
*
|
2018-11-07 |
2022-01-17 |
モデルナティエックス インコーポレイテッド |
Ｒｎａがんワクチン
|
|
TWI852977B
(zh)
|
2019-01-10 |
2024-08-21 |
美商健生生物科技公司 |
前列腺新抗原及其用途
|
|
CA3124837A1
(en)
*
|
2019-01-14 |
2020-07-23 |
Genentech, Inc. |
Methods of treating cancer with a pd-1 axis binding antagonist and an rna vaccine
|
|
US11351242B1
(en)
|
2019-02-12 |
2022-06-07 |
Modernatx, Inc. |
HMPV/hPIV3 mRNA vaccine composition
|
|
US11851694B1
(en)
|
2019-02-20 |
2023-12-26 |
Modernatx, Inc. |
High fidelity in vitro transcription
|
|
JP2022521094A
(ja)
|
2019-02-20 |
2022-04-05 |
モデルナティエックス インコーポレイテッド |
共転写キャッピング用ｒｎａポリメラーゼバリアント
|
|
EP3938507A4
(en)
|
2019-03-11 |
2023-02-22 |
ModernaTX, Inc. |
PROCEDURE FOR IN VITRO FED BATCH TRANSCRIPTION
|
|
CN113905756A
(zh)
*
|
2019-03-11 |
2022-01-07 |
伊沃逊生物科技股份公司 |
使用编码新表位的构建体进行核酸疫苗接种
|
|
MA55321A
(fr)
|
2019-03-15 |
2022-01-19 |
Modernatx Inc |
Vaccins à base d'arn contre le vih
|
|
CA3134945A1
(en)
*
|
2019-03-25 |
2020-10-01 |
Ohio State Innovation Foundation |
Combination immunoregulation and uses thereof
|
|
WO2020242720A1
(en)
*
|
2019-05-02 |
2020-12-03 |
University Of Florida Research Foundation, Inc. |
Compositions for treatment of diffuse intrinsic pontine glioma
|
|
WO2020243561A1
(en)
*
|
2019-05-31 |
2020-12-03 |
Modernatx, Inc. |
Expanded t cell assay
|
|
WO2020247914A1
(en)
*
|
2019-06-07 |
2020-12-10 |
Emory University |
Kras g12v mutant binds to jak1, inhibitors, pharmaceutical compositions, and methods related thereto
|
|
CN110172089B
(zh)
*
|
2019-06-11 |
2020-01-07 |
北京鼎成肽源生物技术有限公司 |
一种kras突变多抗原组合、靶向kras突变肿瘤ctl及其应用
|
|
CN110172480B
(zh)
*
|
2019-06-11 |
2020-01-07 |
北京鼎成肽源生物技术有限公司 |
双抗原表位融合基因重组慢病毒载体、抗原提呈细胞和ctl细胞及其构建方法和应用
|
|
WO2021038089A1
(en)
*
|
2019-08-29 |
2021-03-04 |
Universität Zürich |
Minimal messenger rnas and uses thereof
|
|
EP4061405A1
(en)
|
2019-11-18 |
2022-09-28 |
Janssen Biotech, Inc. |
Vaccines based on mutant calr and jak2 and their uses
|
|
US20230002799A1
(en)
*
|
2019-12-11 |
2023-01-05 |
Vanderbilt University |
Methods of synthesizing mrna and functional proteins from synthetic double stranded dna
|
|
JP2023512072A
(ja)
*
|
2020-01-30 |
2023-03-23 |
モデルナティエックス インコーポレイテッド |
代謝リプログラミングポリペプチドをコードするｍＲＮＡ及びその使用
|
|
EP4096708A1
(en)
*
|
2020-01-31 |
2022-12-07 |
Genentech, Inc. |
Methods of inducing neoepitope-specific t cells with a pd-1 axis binding antagonist and an rna vaccine
|
|
US20230096704A1
(en)
*
|
2020-02-05 |
2023-03-30 |
University Of Florida Research Foundation, Incorporated |
Rna-loaded nanoparticles and use thereof for the treatment of cancer
|
|
US11912930B2
(en)
|
2020-03-11 |
2024-02-27 |
Advansix Resins & Chemicals Llc |
Formulation for the recovery of hydrocarbons including a surfactant system
|
|
KR20220164506A
(ko)
*
|
2020-03-11 |
2022-12-13 |
어드밴식스 레진즈 앤드 케미컬즈 엘엘씨 |
건강관리 제품을 위한 계면활성제
|
|
JP2023522193A
(ja)
*
|
2020-04-17 |
2023-05-29 |
ザ フランシス クリック インスティチュート リミティッド |
抗原プール
|
|
JP2023522249A
(ja)
|
2020-04-22 |
2023-05-29 |
ビオンテック・ソシエタス・エウロパエア |
コロナウイルスワクチン
|
|
US11130787B2
(en)
*
|
2020-06-11 |
2021-09-28 |
MBF Therapeutics, Inc. |
Alphaherpesvirus glycoprotein d-encoding nucleic acid constructs and methods
|
|
CN115803333A
(zh)
|
2020-07-02 |
2023-03-14 |
生命技术公司 |
三核苷酸帽类似物、其制备和用途
|
|
EP4175664A2
(en)
|
2020-07-06 |
2023-05-10 |
Janssen Biotech, Inc. |
Prostate neoantigens and their uses
|
|
EP4194006A4
(en)
*
|
2020-08-04 |
2024-12-04 |
Progeneer Inc. |
mRNA VACCINE WITH AN ADJUVANT CAPABLE OF KINETIC CONTROL
|
|
EP4196139A2
(en)
|
2020-08-12 |
2023-06-21 |
Actym Therapeutics, Inc. |
Immunostimulatory bacteria-based vaccines, therapeutics, and rna delivery platforms
|
|
US11406703B2
(en)
|
2020-08-25 |
2022-08-09 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
|
JP7644229B2
(ja)
|
2020-10-20 |
2025-03-11 |
エスティー ファーム カンパニー リミテッド |
５’－キャッピングされたｒｎａ合成用オリゴヌクレオチド
|
|
WO2022087424A1
(en)
*
|
2020-10-22 |
2022-04-28 |
The Regents Of The University Of California |
Monoamine oxidase blockade therapy for treating cancer through regulating tumor associated macrophages (tams)
|
|
WO2022120560A1
(zh)
*
|
2020-12-08 |
2022-06-16 |
深圳市瑞吉生物科技有限公司 |
一种mRNA剂型的免疫抑制剂及其在制备肿瘤治疗药物中的应用
|
|
WO2022140278A1
(en)
*
|
2020-12-21 |
2022-06-30 |
University Of Florida Research Foundation, Inc. |
Multilamellar rna nanoparticle vaccine against cancer
|
|
CN114717229B
(zh)
*
|
2021-01-05 |
2024-09-10 |
麦塞拿治疗(香港)有限公司 |
治疗性mRNA的无细胞和无载体体外RNA转录方法和核酸分子
|
|
US12329811B2
(en)
|
2021-01-11 |
2025-06-17 |
Modernatx, Inc. |
Seasonal RNA influenza virus vaccines
|
|
US11524023B2
(en)
|
2021-02-19 |
2022-12-13 |
Modernatx, Inc. |
Lipid nanoparticle compositions and methods of formulating the same
|
|
US20240181030A1
(en)
*
|
2021-03-26 |
2024-06-06 |
Modernatx, Inc. |
Pertussis vaccine
|
|
NL2028681B1
(en)
*
|
2021-04-02 |
2022-10-17 |
Nutcracker Therapeutics Inc |
Materials and methods for generating antigen-specific t cells and treating diseases
|
|
CN113186285B
(zh)
*
|
2021-05-10 |
2022-05-24 |
深圳市展行生物有限公司 |
一种辅助诊断胃癌的方法及其使用的miRNA组合
|
|
US20220363937A1
(en)
|
2021-05-14 |
2022-11-17 |
Armstrong World Industries, Inc. |
Stabilization of antimicrobial coatings
|
|
CN113577258B
(zh)
*
|
2021-07-31 |
2024-04-16 |
山东兴瑞生物科技有限公司 |
一种双靶点mRNA疫苗及其制备方法
|
|
CN115703714B
(zh)
*
|
2021-08-13 |
2025-06-10 |
广州谷森制药有限公司 |
阳离子脂质化合物
|
|
WO2023030635A1
(en)
*
|
2021-09-02 |
2023-03-09 |
BioNTech SE |
Potency assay for therapeutic potential of coding nucleic acid
|
|
IL311302A
(en)
|
2021-09-13 |
2024-05-01 |
Oncodna |
A method for creating a pool of double-stranded DNA encoding tumor neoantigens
|
|
EP4147713A1
(en)
*
|
2021-09-13 |
2023-03-15 |
OncoDNA |
A rna vaccine comprising an rna pool generated from a double-stranded dna pool
|
|
EP4147712A1
(en)
|
2021-09-13 |
2023-03-15 |
OncoDNA |
Method to generate a double-stranded dna pool encoding neoantigens of a tumor of a patient
|
|
JP2024542173A
(ja)
|
2021-11-09 |
2024-11-13 |
アクティム・セラピューティクス・インコーポレイテッド |
マクロファージを処置に適している表現型に変換するための免疫刺激細菌および処置のための対象の同定のためのコンパニオン診断法
|
|
US12186387B2
(en)
|
2021-11-29 |
2025-01-07 |
BioNTech SE |
Coronavirus vaccine
|
|
CN116376942A
(zh)
*
|
2021-12-31 |
2023-07-04 |
广州国家实验室 |
mRNA疫苗
|
|
US11878055B1
(en)
|
2022-06-26 |
2024-01-23 |
BioNTech SE |
Coronavirus vaccine
|
|
EP4561602A1
(en)
*
|
2022-07-28 |
2025-06-04 |
Stemcell Technologies Canada Inc. |
Polynucleotides encoding linked antigens and uses thereof
|
|
CN115992152A
(zh)
*
|
2022-09-22 |
2023-04-21 |
浙江大学医学院附属第一医院 |
一种用于乙型肝炎病毒治疗性mRNA疫苗及其制备方法与应用
|
|
EP4600361A1
(en)
*
|
2022-10-07 |
2025-08-13 |
University of Tsukuba |
Design method and production method for nucleic acid construct and protein complex
|
|
CN120569481A
(zh)
*
|
2022-10-19 |
2025-08-29 |
卡利威尔免疫治疗公司 |
编码可溶性pd-1和il-12的核酸及其用途
|
|
WO2024097257A1
(en)
*
|
2022-10-31 |
2024-05-10 |
Gritstone Bio, Inc. |
Combination panel cell-free dna monitoring
|
|
EP4612301A1
(en)
*
|
2022-11-03 |
2025-09-10 |
ModernaTX, Inc. |
Chemical stability of mrna
|
|
EP4364752A1
(en)
|
2022-11-07 |
2024-05-08 |
OncoDNA |
Improved vaccine
|
|
CN116970614A
(zh)
*
|
2022-12-29 |
2023-10-31 |
达冕疫苗(广州)有限公司 |
编码ny-eso-1的核糖核酸疫苗的组合物和方法
|
|
US20240238408A1
(en)
*
|
2023-01-17 |
2024-07-18 |
The University Of Hong Kong |
CANCER IMMUNOTHERAPY BY DELIVERY OF mRNA
|
|
CN119055671A
(zh)
*
|
2023-05-23 |
2024-12-03 |
源生生物科技(青岛)有限责任公司 |
包含miRNA的活性成分及其应用
|
|
WO2025054383A1
(en)
*
|
2023-09-06 |
2025-03-13 |
Modernatx, Inc. |
Chemical stability of mrna
|
|
WO2025080869A1
(en)
*
|
2023-10-11 |
2025-04-17 |
The Regents Of The University Of California |
Pancreatic cancer immunotherapy using cationic lipid and polymer nanocarriers for co-delivery of kras neoantigens and sting and/or other immunomodulators to boost the cancer immunity cycle and treat liver metastasis
|
|
WO2025117816A1
(en)
*
|
2023-12-01 |
2025-06-05 |
Recode Therapeutics, Inc. |
Lipid nanoparticle compositions and uses thereof
|
|
WO2025153053A1
(en)
*
|
2024-01-17 |
2025-07-24 |
Abogen Biosciences (Shanghai) Co., Ltd. |
Composition and methods for inducing antigen specific immunity against kras mutant cells
|
|
WO2025158069A1
(en)
*
|
2024-01-25 |
2025-07-31 |
Rheinische Friedrich-Wilhelms-Universität Bonn |
CONSTRUCT COMPRISING mRNA-STRAND AND RETINOIC ACID-INDUCIBLE GENE I (RIG-I)-LIGAND(S), PHARMACEUTICAL COMPOSITION AND KIT COMPRISING THE SAME
|
|
CN118389553A
(zh)
*
|
2024-03-01 |
2024-07-26 |
中国科学技术大学 |
免疫增效rna分子及其组合物、疫苗与试剂盒
|
|
CN117883558B
(zh)
*
|
2024-03-15 |
2024-06-14 |
山东兴瑞生物科技有限公司 |
靶向肝肿瘤个性化mRNA疫苗的制备方法
|
|
CN119874872B
(zh)
*
|
2025-01-17 |
2025-11-25 |
武汉大学 |
一种mita铰链区突变多肽及其在自身免疫性疾病中的应用
|