JP2020505993A5 - - Google Patents
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- Publication number
- JP2020505993A5 JP2020505993A5 JP2019541727A JP2019541727A JP2020505993A5 JP 2020505993 A5 JP2020505993 A5 JP 2020505993A5 JP 2019541727 A JP2019541727 A JP 2019541727A JP 2019541727 A JP2019541727 A JP 2019541727A JP 2020505993 A5 JP2020505993 A5 JP 2020505993A5
- Authority
- JP
- Japan
- Prior art keywords
- delivery device
- drug
- drug delivery
- elastic portion
- preformed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000012377 drug delivery Methods 0.000 claims description 78
- 229940079593 drug Drugs 0.000 claims description 36
- 239000003814 drug Substances 0.000 claims description 36
- OYYDSUSKLWTMMQ-JKHIJQBDSA-N trospium Chemical compound [N+]12([C@@H]3CC[C@H]2C[C@H](C3)OC(=O)C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CCCC1 OYYDSUSKLWTMMQ-JKHIJQBDSA-N 0.000 claims description 17
- 229960001491 trospium Drugs 0.000 claims description 17
- 239000013583 drug formulation Substances 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 238000002360 preparation method Methods 0.000 claims description 8
- 239000002357 osmotic agent Substances 0.000 claims description 6
- 239000007787 solid Substances 0.000 claims description 6
- 230000002706 hydrostatic effect Effects 0.000 claims description 5
- 230000015572 biosynthetic process Effects 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 4
- 230000003204 osmotic effect Effects 0.000 claims description 4
- 239000011248 coating agent Substances 0.000 claims description 3
- 238000000576 coating method Methods 0.000 claims description 3
- 238000001727 in vivo Methods 0.000 claims description 3
- 238000003780 insertion Methods 0.000 claims description 3
- 230000037431 insertion Effects 0.000 claims description 3
- 239000003149 muscarinic antagonist Substances 0.000 claims description 3
- 229920000052 poly(p-xylylene) Polymers 0.000 claims description 3
- 238000004891 communication Methods 0.000 claims description 2
- 229920001971 elastomer Polymers 0.000 claims description 2
- 239000000806 elastomer Substances 0.000 claims description 2
- 239000012530 fluid Substances 0.000 claims description 2
- 230000000452 restraining effect Effects 0.000 claims description 2
- 230000001052 transient effect Effects 0.000 claims description 2
- 238000000034 method Methods 0.000 description 23
- 238000012986 modification Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 208000020431 spinal cord injury Diseases 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- 206010020853 Hypertonic bladder Diseases 0.000 description 1
- 208000009722 Overactive Urinary Bladder Diseases 0.000 description 1
- 206010037211 Psychomotor hyperactivity Diseases 0.000 description 1
- 206010046543 Urinary incontinence Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000001272 neurogenic effect Effects 0.000 description 1
- 208000020629 overactive bladder Diseases 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023176139A JP7789045B2 (ja) | 2017-02-01 | 2023-10-11 | インビボ薬物送達デバイスおよび薬物送達のための方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762453333P | 2017-02-01 | 2017-02-01 | |
| US62/453,333 | 2017-02-01 | ||
| US201762480744P | 2017-04-03 | 2017-04-03 | |
| US62/480,744 | 2017-04-03 | ||
| PCT/US2018/016463 WO2018144738A1 (en) | 2017-02-01 | 2018-02-01 | In vivo drug delivery devices and methods for drug delivery |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023176139A Division JP7789045B2 (ja) | 2017-02-01 | 2023-10-11 | インビボ薬物送達デバイスおよび薬物送達のための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020505993A JP2020505993A (ja) | 2020-02-27 |
| JP2020505993A5 true JP2020505993A5 (https=) | 2021-03-11 |
| JP7366748B2 JP7366748B2 (ja) | 2023-10-23 |
Family
ID=61231348
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019541727A Active JP7366748B2 (ja) | 2017-02-01 | 2018-02-01 | インビボ薬物送達デバイスおよび薬物送達のための方法 |
| JP2023176139A Active JP7789045B2 (ja) | 2017-02-01 | 2023-10-11 | インビボ薬物送達デバイスおよび薬物送達のための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023176139A Active JP7789045B2 (ja) | 2017-02-01 | 2023-10-11 | インビボ薬物送達デバイスおよび薬物送達のための方法 |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US11020575B2 (https=) |
| EP (1) | EP3432970B1 (https=) |
| JP (2) | JP7366748B2 (https=) |
| KR (1) | KR102564771B1 (https=) |
| CN (1) | CN110418658A (https=) |
| AU (2) | AU2018217094B2 (https=) |
| CY (1) | CY1124192T1 (https=) |
| DK (1) | DK3432970T3 (https=) |
| ES (1) | ES2873084T3 (https=) |
| HR (1) | HRP20210571T1 (https=) |
| HU (1) | HUE054587T2 (https=) |
| IL (1) | IL268385B (https=) |
| LT (1) | LT3432970T (https=) |
| MX (2) | MX2019009080A (https=) |
| PL (1) | PL3432970T3 (https=) |
| PT (1) | PT3432970T (https=) |
| RS (1) | RS62459B1 (https=) |
| RU (1) | RU2759868C2 (https=) |
| SG (1) | SG11201907033SA (https=) |
| SI (1) | SI3432970T1 (https=) |
| SM (1) | SMT202100310T1 (https=) |
| WO (1) | WO2018144738A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019178134A1 (en) * | 2018-03-13 | 2019-09-19 | Semma Therapeutics, Inc. | Implantation devices, system, and methods |
| CN112839653A (zh) * | 2018-08-01 | 2021-05-25 | 塔里斯生物医药公司 | 使用曲司氯铵治疗膀胱过度活动症的方法 |
| CN109765118B (zh) * | 2018-12-22 | 2021-09-17 | 临沂协润工贸有限公司 | 一种纺织品韧性测试仪 |
| KR20220146361A (ko) * | 2021-04-23 | 2022-11-01 | 김승범 | 과민성 방광 치료 장치 |
| CN113274624B (zh) * | 2021-07-06 | 2023-05-12 | 中南大学湘雅医院 | 一种可视化尿道扩张术后治疗仪 |
| EP4710986A2 (en) | 2021-12-21 | 2026-03-18 | TARIS Biomedical LLC | Urinary placement catheter for intravesical devices |
| CN119072311A (zh) | 2022-02-18 | 2024-12-03 | 塔里斯生物医药公司 | 用于膀胱内施用的厄达替尼制剂和渗透系统 |
| WO2024092159A1 (en) | 2022-10-28 | 2024-05-02 | Taris Biomedical Llc | Methods of treating bladder cancer with gemcitabine |
| JP2026506041A (ja) | 2023-02-17 | 2026-02-20 | タリス バイオメディカル エルエルシー | 膀胱がんの治療における使用のための膀胱内投与のためのエルダフィチニブ |
| WO2024215682A1 (en) | 2023-04-10 | 2024-10-17 | Taris Biomedical Llc | Gemcitabine for use in methods of treating high-risk non-muscle invasive bladder cancer unresponsive to bacillus calmette-guerin therapy |
| WO2025076007A1 (en) | 2023-10-02 | 2025-04-10 | Taris Biomedical Llc | Methods of treating high-risk non-muscle invasive bladder cancer unresponsive to bacillus calmette-guérin therapy |
| WO2026058217A1 (en) | 2024-09-13 | 2026-03-19 | Taris Biomedical Llc | Intravesical gemcitabine for use in treating bacillus calmette-guérin (bcg)-naive high-risk non-muscle invasive bladder cancer (hr-nmibc) |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4210139A (en) | 1979-01-17 | 1980-07-01 | Alza Corporation | Osmotic device with compartment for governing concentration of agent dispensed from device |
| US4657536A (en) | 1979-04-13 | 1987-04-14 | Regents Of The University Of Minnesota | Check valve catheter |
| US5340590A (en) | 1987-06-25 | 1994-08-23 | Alza Corporation | Delivery system with bilayer osmotic engine |
| US5456679A (en) | 1992-02-18 | 1995-10-10 | Alza Corporation | Delivery devices with pulsatile effect |
| US5221278A (en) | 1992-03-12 | 1993-06-22 | Alza Corporation | Osmotically driven delivery device with expandable orifice for pulsatile delivery effect |
| ATE195252T1 (de) | 1993-04-23 | 2000-08-15 | Novartis Erfind Verwalt Gmbh | Wirkstoffabgabevorrichtung mit gesteuerter freigabe |
| ZA981610B (en) * | 1997-03-24 | 1999-08-26 | Alza Corp | Self adjustable exit port. |
| US6436091B1 (en) * | 1999-11-16 | 2002-08-20 | Microsolutions, Inc. | Methods and implantable devices and systems for long term delivery of a pharmaceutical agent |
| US8740973B2 (en) * | 2001-10-26 | 2014-06-03 | Icon Medical Corp. | Polymer biodegradable medical device |
| ATE387236T1 (de) | 2003-03-31 | 2008-03-15 | Alza Corp | Osmotische pumpe mit mitteln zum ableiten des innendrucks |
| MXPA06002967A (es) | 2003-09-30 | 2006-06-14 | Alza Corp | Aparato de suministro de agente activo de conduccion osmotica que proporciona perfil de liberacion ascendente. |
| US7455688B2 (en) * | 2004-11-12 | 2008-11-25 | Con Interventional Systems, Inc. | Ostial stent |
| DK1933810T3 (da) | 2005-08-11 | 2013-01-28 | Childrens Medical Center | Intravesikal lægemiddelafgivelsesindretning og fremgangsmåde |
| EP2049081B1 (en) | 2006-08-09 | 2012-11-14 | Intarcia Therapeutics, Inc. | Osmotic delivery systems and piston assemblies |
| KR101538748B1 (ko) * | 2007-12-11 | 2015-07-22 | 메사추세츠 인스티튜트 오브 테크놀로지 | 이식형 의약 투여 장치와 방광과 기타 신체 낭 또는 내강의 치료 방법 |
| EA201170297A1 (ru) * | 2008-08-09 | 2011-08-30 | Массачусетс Инститьют Оф Текнолоджи | Имплантируемое устройство для доставки лекарственных средств и способ лечения мужской мочеполовой системы и окружающих тканей |
| DK2445570T3 (da) * | 2009-06-26 | 2013-02-25 | Taris Biomedical Inc | Implanterbare lægemiddelafgivelsesindretninger samt fremgangsmåder til deres fremstilling |
| US8721621B2 (en) | 2009-09-10 | 2014-05-13 | Taris Biomedical, Inc. | Systems and methods for deploying devices to genitourinary sites |
| US9017312B2 (en) * | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
| US8167836B2 (en) | 2009-12-08 | 2012-05-01 | Taris Biomedical, Inc. | Tissue expander configured for drug delivery |
| PL3884988T3 (pl) | 2009-12-17 | 2025-09-08 | Taris Biomedical Llc | Urządzenie implantowalne z tolerancją wewnątrzpęcherzową |
| US20110218488A1 (en) | 2010-03-05 | 2011-09-08 | Taris Biomedical, Inc. | Systems and Methods for Implanting Devices in the Bladder and Other Genitourinary Sites |
| EP3795121A1 (en) * | 2010-08-05 | 2021-03-24 | TARIS Biomedical LLC | Ureteral stent drug delivery device |
| US9457176B2 (en) | 2010-10-06 | 2016-10-04 | Taris Biomedical Llc | Implantable drug delivery device with bladder retention feature |
| WO2012048114A1 (en) * | 2010-10-06 | 2012-04-12 | Taris Biomedical, Inc. | Time-selective bioresorbable or collapsible drug delivery systems and methods |
| JP2014503554A (ja) | 2011-01-10 | 2014-02-13 | タリス バイオメディカル，インコーポレイテッド | 膀胱痛及び刺激性排尿の持続的治療の使用のためのリドカインレジメン |
| EP2670398B1 (en) | 2011-02-04 | 2017-06-07 | TARIS Biomedical LLC | Implantable device for controlled release of low solubility drug |
| CA2872092C (en) * | 2012-04-30 | 2021-02-16 | Taris Biomedical, Inc. | Methods for treatment of pelvic pain and/or comorbid conditions |
| WO2014031676A1 (en) * | 2012-08-20 | 2014-02-27 | O-Ray Pharma, Inc. | Process for manufacturing drug delivery formulations |
| MX379066B (es) * | 2012-09-18 | 2025-03-04 | Taris Biomedical Llc | Sistemas de administracion de farmaco y metodos para el tratamiento de la disfuncion miccional de la vejiga y otros trastornos del tracto urinario inferior. |
| JP2016508842A (ja) * | 2013-03-05 | 2016-03-24 | タリス バイオメディカル エルエルシー | 装置の開口部を通じて制御された薬物放出のための薬物送達装置及び方法 |
| US9533101B2 (en) | 2013-03-14 | 2017-01-03 | Leonard Allen Massey, JR. | Multi-cycle and auto-disable syringe and method of use thereof |
| KR102557326B1 (ko) * | 2013-03-15 | 2023-07-19 | 타리스 바이오메디컬 엘엘씨 | 약물-투과성 구성요소를 가지는 약물 전달 장치 |
| EP2968120B1 (en) * | 2013-03-15 | 2026-01-14 | TARIS Biomedical LLC | Drug delivery devices and methods for drug delivery |
| KR102385603B1 (ko) | 2013-08-19 | 2022-04-11 | 타리스 바이오메디컬 엘엘씨 | 다중 유닛 약물 전달 장치 및 방법 |
| EP3065807A1 (en) * | 2013-11-05 | 2016-09-14 | TARIS Biomedical LLC | Osmotic drug delivery devices, kits, and methods |
| US20170246437A1 (en) * | 2014-09-12 | 2017-08-31 | Taris Biomedical Llc | pH-MODULATING DRUG DELIVERY DEVICES AND METHODS |
| CN104998344A (zh) * | 2015-07-27 | 2015-10-28 | 肖雁冰 | 记忆合金硅胶宫内缓释系统 |
-
2018
- 2018-02-01 PT PT187057864T patent/PT3432970T/pt unknown
- 2018-02-01 WO PCT/US2018/016463 patent/WO2018144738A1/en not_active Ceased
- 2018-02-01 HU HUE18705786A patent/HUE054587T2/hu unknown
- 2018-02-01 EP EP18705786.4A patent/EP3432970B1/en active Active
- 2018-02-01 CN CN201880013473.1A patent/CN110418658A/zh active Pending
- 2018-02-01 PL PL18705786T patent/PL3432970T3/pl unknown
- 2018-02-01 JP JP2019541727A patent/JP7366748B2/ja active Active
- 2018-02-01 AU AU2018217094A patent/AU2018217094B2/en active Active
- 2018-02-01 SI SI201830302T patent/SI3432970T1/sl unknown
- 2018-02-01 SM SM20210310T patent/SMT202100310T1/it unknown
- 2018-02-01 RU RU2019126979A patent/RU2759868C2/ru active
- 2018-02-01 MX MX2019009080A patent/MX2019009080A/es unknown
- 2018-02-01 RS RS20210609A patent/RS62459B1/sr unknown
- 2018-02-01 LT LTEP18705786.4T patent/LT3432970T/lt unknown
- 2018-02-01 US US16/302,061 patent/US11020575B2/en active Active
- 2018-02-01 SG SG11201907033SA patent/SG11201907033SA/en unknown
- 2018-02-01 DK DK18705786.4T patent/DK3432970T3/da active
- 2018-02-01 HR HRP20210571TT patent/HRP20210571T1/hr unknown
- 2018-02-01 KR KR1020197025677A patent/KR102564771B1/ko active Active
- 2018-02-01 ES ES18705786T patent/ES2873084T3/es active Active
-
2019
- 2019-07-31 IL IL268385A patent/IL268385B/en active IP Right Grant
- 2019-07-31 MX MX2024006288A patent/MX2024006288A/es unknown
-
2021
- 2021-05-26 US US17/331,028 patent/US12090292B2/en active Active
- 2021-06-01 CY CY20211100479T patent/CY1124192T1/el unknown
-
2023
- 2023-08-24 AU AU2023219908A patent/AU2023219908B2/en not_active Expired - Fee Related
- 2023-10-11 JP JP2023176139A patent/JP7789045B2/ja active Active
-
2024
- 2024-09-04 US US18/824,361 patent/US20240424269A1/en active Pending
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