JP2020505993A5 - - Google Patents
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- Publication number
- JP2020505993A5 JP2020505993A5 JP2019541727A JP2019541727A JP2020505993A5 JP 2020505993 A5 JP2020505993 A5 JP 2020505993A5 JP 2019541727 A JP2019541727 A JP 2019541727A JP 2019541727 A JP2019541727 A JP 2019541727A JP 2020505993 A5 JP2020505993 A5 JP 2020505993A5
- Authority
- JP
- Japan
- Prior art keywords
- delivery device
- drug
- drug delivery
- elastic portion
- preformed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000012377 drug delivery Methods 0.000 claims description 78
- 229940079593 drug Drugs 0.000 claims description 36
- 239000003814 drug Substances 0.000 claims description 36
- OYYDSUSKLWTMMQ-JKHIJQBDSA-N trospium Chemical compound [N+]12([C@@H]3CC[C@H]2C[C@H](C3)OC(=O)C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CCCC1 OYYDSUSKLWTMMQ-JKHIJQBDSA-N 0.000 claims description 17
- 229960001491 trospium Drugs 0.000 claims description 17
- 239000013583 drug formulation Substances 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 238000002360 preparation method Methods 0.000 claims description 8
- 239000002357 osmotic agent Substances 0.000 claims description 6
- 239000007787 solid Substances 0.000 claims description 6
- 230000002706 hydrostatic effect Effects 0.000 claims description 5
- 230000015572 biosynthetic process Effects 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 4
- 230000003204 osmotic effect Effects 0.000 claims description 4
- 239000011248 coating agent Substances 0.000 claims description 3
- 238000000576 coating method Methods 0.000 claims description 3
- 238000001727 in vivo Methods 0.000 claims description 3
- 238000003780 insertion Methods 0.000 claims description 3
- 230000037431 insertion Effects 0.000 claims description 3
- 239000003149 muscarinic antagonist Substances 0.000 claims description 3
- 229920000052 poly(p-xylylene) Polymers 0.000 claims description 3
- 238000004891 communication Methods 0.000 claims description 2
- 229920001971 elastomer Polymers 0.000 claims description 2
- 239000000806 elastomer Substances 0.000 claims description 2
- 239000012530 fluid Substances 0.000 claims description 2
- 230000000452 restraining effect Effects 0.000 claims description 2
- 230000001052 transient effect Effects 0.000 claims description 2
- 238000000034 method Methods 0.000 description 23
- 238000012986 modification Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 208000020431 spinal cord injury Diseases 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- 206010020853 Hypertonic bladder Diseases 0.000 description 1
- 208000009722 Overactive Urinary Bladder Diseases 0.000 description 1
- 206010037211 Psychomotor hyperactivity Diseases 0.000 description 1
- 206010046543 Urinary incontinence Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000001272 neurogenic effect Effects 0.000 description 1
- 208000020629 overactive bladder Diseases 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023176139A JP7789045B2 (ja) | 2017-02-01 | 2023-10-11 | インビボ薬物送達デバイスおよび薬物送達のための方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762453333P | 2017-02-01 | 2017-02-01 | |
| US62/453,333 | 2017-02-01 | ||
| US201762480744P | 2017-04-03 | 2017-04-03 | |
| US62/480,744 | 2017-04-03 | ||
| PCT/US2018/016463 WO2018144738A1 (en) | 2017-02-01 | 2018-02-01 | In vivo drug delivery devices and methods for drug delivery |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023176139A Division JP7789045B2 (ja) | 2017-02-01 | 2023-10-11 | インビボ薬物送達デバイスおよび薬物送達のための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020505993A JP2020505993A (ja) | 2020-02-27 |
| JP2020505993A5 true JP2020505993A5 (https=) | 2021-03-11 |
| JP7366748B2 JP7366748B2 (ja) | 2023-10-23 |
Family
ID=61231348
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019541727A Active JP7366748B2 (ja) | 2017-02-01 | 2018-02-01 | インビボ薬物送達デバイスおよび薬物送達のための方法 |
| JP2023176139A Active JP7789045B2 (ja) | 2017-02-01 | 2023-10-11 | インビボ薬物送達デバイスおよび薬物送達のための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023176139A Active JP7789045B2 (ja) | 2017-02-01 | 2023-10-11 | インビボ薬物送達デバイスおよび薬物送達のための方法 |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US11020575B2 (https=) |
| EP (1) | EP3432970B1 (https=) |
| JP (2) | JP7366748B2 (https=) |
| KR (1) | KR102564771B1 (https=) |
| CN (1) | CN110418658A (https=) |
| AU (2) | AU2018217094B2 (https=) |
| CY (1) | CY1124192T1 (https=) |
| DK (1) | DK3432970T3 (https=) |
| ES (1) | ES2873084T3 (https=) |
| HR (1) | HRP20210571T1 (https=) |
| HU (1) | HUE054587T2 (https=) |
| IL (1) | IL268385B (https=) |
| LT (1) | LT3432970T (https=) |
| MX (2) | MX2019009080A (https=) |
| PL (1) | PL3432970T3 (https=) |
| PT (1) | PT3432970T (https=) |
| RS (1) | RS62459B1 (https=) |
| RU (1) | RU2759868C2 (https=) |
| SG (1) | SG11201907033SA (https=) |
| SI (1) | SI3432970T1 (https=) |
| SM (1) | SMT202100310T1 (https=) |
| WO (1) | WO2018144738A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12377252B2 (en) * | 2018-03-13 | 2025-08-05 | Vertex Pharmaceuticals Incorporated | Implantation devices, system, and methods |
| CN112839653A (zh) * | 2018-08-01 | 2021-05-25 | 塔里斯生物医药公司 | 使用曲司氯铵治疗膀胱过度活动症的方法 |
| CN109765118B (zh) * | 2018-12-22 | 2021-09-17 | 临沂协润工贸有限公司 | 一种纺织品韧性测试仪 |
| WO2022225379A1 (ko) * | 2021-04-23 | 2022-10-27 | 김승범 | 과민성 방광 치료 장치 |
| CN113274624B (zh) * | 2021-07-06 | 2023-05-12 | 中南大学湘雅医院 | 一种可视化尿道扩张术后治疗仪 |
| EP4710986A2 (en) | 2021-12-21 | 2026-03-18 | TARIS Biomedical LLC | Urinary placement catheter for intravesical devices |
| KR20240145513A (ko) | 2022-02-18 | 2024-10-07 | 타리스 바이오메디컬 엘엘씨 | 에르다피티닙 제형 및 방광내 투여를 위한 삼투성 시스템 |
| WO2024092159A1 (en) | 2022-10-28 | 2024-05-02 | Taris Biomedical Llc | Methods of treating bladder cancer with gemcitabine |
| CN120731077A (zh) | 2023-02-17 | 2025-09-30 | 塔里斯生物医药公司 | 膀胱内施用厄达替尼以用于治疗膀胱癌 |
| KR20250168664A (ko) | 2023-04-10 | 2025-12-02 | 타리스 바이오메디컬 엘엘씨 | 바실루스 칼메트-구에린 요법에 무반응성인 고위험 근육 비침습성 방광암을 치료하는 방법에 사용하기 위한 젬시타빈 |
| TW202532086A (zh) | 2023-10-02 | 2025-08-16 | 美商塔里斯生物醫學有限責任公司 | 治療對卡介苗療法無反應之高風險非肌肉侵襲性膀胱癌之方法 |
| WO2026058217A1 (en) | 2024-09-13 | 2026-03-19 | Taris Biomedical Llc | Intravesical gemcitabine for use in treating bacillus calmette-guérin (bcg)-naive high-risk non-muscle invasive bladder cancer (hr-nmibc) |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4210139A (en) | 1979-01-17 | 1980-07-01 | Alza Corporation | Osmotic device with compartment for governing concentration of agent dispensed from device |
| US4657536A (en) | 1979-04-13 | 1987-04-14 | Regents Of The University Of Minnesota | Check valve catheter |
| US5340590A (en) | 1987-06-25 | 1994-08-23 | Alza Corporation | Delivery system with bilayer osmotic engine |
| US5456679A (en) | 1992-02-18 | 1995-10-10 | Alza Corporation | Delivery devices with pulsatile effect |
| US5221278A (en) | 1992-03-12 | 1993-06-22 | Alza Corporation | Osmotically driven delivery device with expandable orifice for pulsatile delivery effect |
| DE69425453T2 (de) | 1993-04-23 | 2001-04-12 | Novartis Ag, Basel | Wirkstoffabgabevorrichtung mit gesteuerter Freigabe |
| ZA981610B (en) * | 1997-03-24 | 1999-08-26 | Alza Corp | Self adjustable exit port. |
| US6436091B1 (en) * | 1999-11-16 | 2002-08-20 | Microsolutions, Inc. | Methods and implantable devices and systems for long term delivery of a pharmaceutical agent |
| US8740973B2 (en) * | 2001-10-26 | 2014-06-03 | Icon Medical Corp. | Polymer biodegradable medical device |
| DE602004012081T2 (de) | 2003-03-31 | 2009-03-19 | Intarcia Therapeutics, Inc., Emeryville | Osmotische pumpe mit mitteln zum ableiten des innendrucks |
| MXPA06002967A (es) | 2003-09-30 | 2006-06-14 | Alza Corp | Aparato de suministro de agente activo de conduccion osmotica que proporciona perfil de liberacion ascendente. |
| US7455688B2 (en) * | 2004-11-12 | 2008-11-25 | Con Interventional Systems, Inc. | Ostial stent |
| JP5265359B2 (ja) | 2005-08-11 | 2013-08-14 | マサチューセッツ インスティテュート オブ テクノロジー | 膀胱内薬物送達デバイスおよび方法 |
| EP2359808B1 (en) | 2006-08-09 | 2013-05-22 | Intarcia Therapeutics, Inc | Osmotic delivery systems and piston assemblies |
| US9586035B2 (en) * | 2007-12-11 | 2017-03-07 | Massachusetts Institute Of Technology | Implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens |
| EA201170297A1 (ru) * | 2008-08-09 | 2011-08-30 | Массачусетс Инститьют Оф Текнолоджи | Имплантируемое устройство для доставки лекарственных средств и способ лечения мужской мочеполовой системы и окружающих тканей |
| CN102470237A (zh) | 2009-06-26 | 2012-05-23 | 塔里斯生物医药公司 | 用于可植入药物递送装置的固体药物片剂 |
| US8721621B2 (en) | 2009-09-10 | 2014-05-13 | Taris Biomedical, Inc. | Systems and methods for deploying devices to genitourinary sites |
| US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
| US8167836B2 (en) | 2009-12-08 | 2012-05-01 | Taris Biomedical, Inc. | Tissue expander configured for drug delivery |
| PL3884988T3 (pl) | 2009-12-17 | 2025-09-08 | Taris Biomedical Llc | Urządzenie implantowalne z tolerancją wewnątrzpęcherzową |
| US20110218488A1 (en) | 2010-03-05 | 2011-09-08 | Taris Biomedical, Inc. | Systems and Methods for Implanting Devices in the Bladder and Other Genitourinary Sites |
| DK2600800T3 (da) * | 2010-08-05 | 2020-11-16 | Taris Biomedical Llc | Indretning til lægemiddellevering i en ureterstent og kit dertil |
| JP5945544B2 (ja) * | 2010-10-06 | 2016-07-05 | タリス バイオメディカル エルエルシー | 時間選択的に生体吸収可能または崩壊可能な薬剤送達システムおよび方法 |
| US9457176B2 (en) * | 2010-10-06 | 2016-10-04 | Taris Biomedical Llc | Implantable drug delivery device with bladder retention feature |
| US9114111B2 (en) | 2011-01-10 | 2015-08-25 | Allergan, Inc. | Methods for sustained treatment of bladder pain and irritative voiding |
| AU2012211960B2 (en) | 2011-02-04 | 2016-12-01 | Taris Biomedical Llc | Implantable device for controlled release of low solubility drug |
| EP2844240A1 (en) * | 2012-04-30 | 2015-03-11 | Allergan, Inc. | Methods for treatment of pelvic pain and / or comorbid conditions |
| CN104582782B (zh) * | 2012-08-20 | 2018-11-27 | 奥雷制药有限公司 | 用于制备药物递送制剂的方法 |
| BR112015005351A2 (pt) | 2012-09-18 | 2017-07-04 | Taris Biomedical Llc | sistemas para distribuição de drogas e métodos para tratamento de disfunção de esvaziamento da bexiga e outros distúrbios do trato urinário inferior |
| EP2964310A1 (en) * | 2013-03-05 | 2016-01-13 | TARIS Biomedical LLC | Drug delivery devices and methods for controlled drug release through device orifice |
| US9533101B2 (en) | 2013-03-14 | 2017-01-03 | Leonard Allen Massey, JR. | Multi-cycle and auto-disable syringe and method of use thereof |
| JP6697376B2 (ja) * | 2013-03-15 | 2020-05-20 | タリス バイオメディカル エルエルシー | 薬物送達のための薬物送達装置及び方法 |
| PT2968880T (pt) * | 2013-03-15 | 2025-07-07 | Taris Biomedical Llc | Dispositivos de aplicação de fármaco com componente permeável a fármaco |
| CN113413393B (zh) | 2013-08-19 | 2025-03-04 | 塔里斯生物医药公司 | 多单元药物递送装置和方法 |
| BR112016010103A8 (pt) * | 2013-11-05 | 2018-01-30 | Taris Biomedical Llc | métodos, kits e dispositivos de suprimento de fármaco osmótico. |
| WO2016040904A1 (en) * | 2014-09-12 | 2016-03-17 | Taris Biomedical Llc | Ph-modulating drug delivery devices and methods |
| CN104998344A (zh) * | 2015-07-27 | 2015-10-28 | 肖雁冰 | 记忆合金硅胶宫内缓释系统 |
-
2018
- 2018-02-01 SG SG11201907033SA patent/SG11201907033SA/en unknown
- 2018-02-01 ES ES18705786T patent/ES2873084T3/es active Active
- 2018-02-01 DK DK18705786.4T patent/DK3432970T3/da active
- 2018-02-01 WO PCT/US2018/016463 patent/WO2018144738A1/en not_active Ceased
- 2018-02-01 LT LTEP18705786.4T patent/LT3432970T/lt unknown
- 2018-02-01 HR HRP20210571TT patent/HRP20210571T1/hr unknown
- 2018-02-01 US US16/302,061 patent/US11020575B2/en active Active
- 2018-02-01 KR KR1020197025677A patent/KR102564771B1/ko active Active
- 2018-02-01 PL PL18705786T patent/PL3432970T3/pl unknown
- 2018-02-01 EP EP18705786.4A patent/EP3432970B1/en active Active
- 2018-02-01 PT PT187057864T patent/PT3432970T/pt unknown
- 2018-02-01 AU AU2018217094A patent/AU2018217094B2/en active Active
- 2018-02-01 RS RS20210609A patent/RS62459B1/sr unknown
- 2018-02-01 RU RU2019126979A patent/RU2759868C2/ru active
- 2018-02-01 MX MX2019009080A patent/MX2019009080A/es unknown
- 2018-02-01 SM SM20210310T patent/SMT202100310T1/it unknown
- 2018-02-01 JP JP2019541727A patent/JP7366748B2/ja active Active
- 2018-02-01 CN CN201880013473.1A patent/CN110418658A/zh active Pending
- 2018-02-01 HU HUE18705786A patent/HUE054587T2/hu unknown
- 2018-02-01 SI SI201830302T patent/SI3432970T1/sl unknown
-
2019
- 2019-07-31 MX MX2024006288A patent/MX2024006288A/es unknown
- 2019-07-31 IL IL268385A patent/IL268385B/en active IP Right Grant
-
2021
- 2021-05-26 US US17/331,028 patent/US12090292B2/en active Active
- 2021-06-01 CY CY20211100479T patent/CY1124192T1/el unknown
-
2023
- 2023-08-24 AU AU2023219908A patent/AU2023219908B2/en not_active Expired - Fee Related
- 2023-10-11 JP JP2023176139A patent/JP7789045B2/ja active Active
-
2024
- 2024-09-04 US US18/824,361 patent/US20240424269A1/en active Pending
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