JP2017500171A5 - - Google Patents
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- Publication number
- JP2017500171A5 JP2017500171A5 JP2016552464A JP2016552464A JP2017500171A5 JP 2017500171 A5 JP2017500171 A5 JP 2017500171A5 JP 2016552464 A JP2016552464 A JP 2016552464A JP 2016552464 A JP2016552464 A JP 2016552464A JP 2017500171 A5 JP2017500171 A5 JP 2017500171A5
- Authority
- JP
- Japan
- Prior art keywords
- fluid
- reservoir
- elongated tube
- precursor
- tube
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012530 fluid Substances 0.000 claims 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 15
- 239000002243 precursor Substances 0.000 claims 11
- 239000002357 osmotic agent Substances 0.000 claims 10
- 229940079593 drug Drugs 0.000 claims 9
- 239000003814 drug Substances 0.000 claims 9
- 239000000126 substance Substances 0.000 claims 6
- 239000007787 solid Substances 0.000 claims 5
- 230000003204 osmotic effect Effects 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 229920001477 hydrophilic polymer Polymers 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 229920001296 polysiloxane Polymers 0.000 claims 2
- 239000002904 solvent Substances 0.000 claims 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
- XIQVNETUBQGFHX-UHFFFAOYSA-N Ditropan Chemical compound C=1C=CC=CC=1C(O)(C(=O)OCC#CCN(CC)CC)C1CCCCC1 XIQVNETUBQGFHX-UHFFFAOYSA-N 0.000 claims 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 claims 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- 239000004433 Thermoplastic polyurethane Substances 0.000 claims 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 1
- 230000003444 anaesthetic effect Effects 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 239000004202 carbamide Substances 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 238000007599 discharging Methods 0.000 claims 1
- 239000002526 disodium citrate Substances 0.000 claims 1
- 235000019262 disodium citrate Nutrition 0.000 claims 1
- CEYULKASIQJZGP-UHFFFAOYSA-L disodium;2-(carboxymethyl)-2-hydroxybutanedioate Chemical compound [Na+].[Na+].[O-]C(=O)CC(O)(C(=O)O)CC([O-])=O CEYULKASIQJZGP-UHFFFAOYSA-L 0.000 claims 1
- 239000003684 drug solvent Substances 0.000 claims 1
- SDUQYLNIPVEERB-QPPQHZFASA-N gemcitabine Chemical compound O=C1N=C(N)C=CN1[C@H]1C(F)(F)[C@H](O)[C@@H](CO)O1 SDUQYLNIPVEERB-QPPQHZFASA-N 0.000 claims 1
- 229960005277 gemcitabine Drugs 0.000 claims 1
- 230000005484 gravity Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 239000008101 lactose Substances 0.000 claims 1
- 229960004194 lidocaine Drugs 0.000 claims 1
- 230000014759 maintenance of location Effects 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- HWPKGOGLCKPRLZ-UHFFFAOYSA-M monosodium citrate Chemical compound [Na+].OC(=O)CC(O)(C([O-])=O)CC(O)=O HWPKGOGLCKPRLZ-UHFFFAOYSA-M 0.000 claims 1
- 239000002524 monosodium citrate Substances 0.000 claims 1
- 235000018342 monosodium citrate Nutrition 0.000 claims 1
- 239000003149 muscarinic antagonist Substances 0.000 claims 1
- 229960001756 oxaliplatin Drugs 0.000 claims 1
- DWAFYCQODLXJNR-BNTLRKBRSA-L oxaliplatin Chemical compound O1C(=O)C(=O)O[Pt]11N[C@@H]2CCCC[C@H]2N1 DWAFYCQODLXJNR-BNTLRKBRSA-L 0.000 claims 1
- 229960005434 oxybutynin Drugs 0.000 claims 1
- 229920000052 poly(p-xylylene) Polymers 0.000 claims 1
- 229920002635 polyurethane Polymers 0.000 claims 1
- 239000004814 polyurethane Substances 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 239000001509 sodium citrate Substances 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 229920002803 thermoplastic polyurethane Polymers 0.000 claims 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 claims 1
- 229940038773 trisodium citrate Drugs 0.000 claims 1
- 235000019263 trisodium citrate Nutrition 0.000 claims 1
- 229960001491 trospium Drugs 0.000 claims 1
- OYYDSUSKLWTMMQ-JKHIJQBDSA-N trospium Chemical compound [N+]12([C@@H]3CC[C@H]2C[C@H](C3)OC(=O)C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CCCC1 OYYDSUSKLWTMMQ-JKHIJQBDSA-N 0.000 claims 1
- 210000003708 urethra Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361899982P | 2013-11-05 | 2013-11-05 | |
| US61/899,982 | 2013-11-05 | ||
| PCT/US2014/064063 WO2015069723A1 (en) | 2013-11-05 | 2014-11-05 | Osmotic drug delivery devices, kits, and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017500171A JP2017500171A (ja) | 2017-01-05 |
| JP2017500171A5 true JP2017500171A5 (https=) | 2017-12-07 |
Family
ID=51946057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016552464A Pending JP2017500171A (ja) | 2013-11-05 | 2014-11-05 | 浸透圧薬物送達デバイス、キット、及び方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20160279399A1 (https=) |
| EP (1) | EP3065807A1 (https=) |
| JP (1) | JP2017500171A (https=) |
| KR (1) | KR20160083061A (https=) |
| CN (1) | CN105792880A (https=) |
| BR (1) | BR112016010103A8 (https=) |
| CA (1) | CA2929554A1 (https=) |
| IL (1) | IL245445A0 (https=) |
| RU (1) | RU2016120199A (https=) |
| WO (1) | WO2015069723A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2964310A1 (en) | 2013-03-05 | 2016-01-13 | TARIS Biomedical LLC | Drug delivery devices and methods for controlled drug release through device orifice |
| US20150250717A1 (en) * | 2014-03-06 | 2015-09-10 | Taris Biomedical Llc | Drug delivery systems and methods for treatment of bladder cancer with gemcitabine |
| US10010400B2 (en) | 2015-03-30 | 2018-07-03 | Taris Biomedical Llc | Devices and methods for local delivery of drug to upper urinary tract |
| US9867974B2 (en) * | 2015-06-01 | 2018-01-16 | Wisconsin Alumni Research Foundation | Microfluidic device for multiplexed point source administration of compounds |
| SG11201907033SA (en) | 2017-02-01 | 2019-08-27 | Taris Biomedical Llc | In vivo drug delivery devices and methods for drug delivery |
| SG10201913998YA (en) | 2017-07-25 | 2020-03-30 | Taris Biomedical Llc | Methods of treating tumor metastasis |
| JP7138702B2 (ja) | 2017-09-22 | 2022-09-16 | ベクトン・ディキンソン・アンド・カンパニー | カテーテルロック溶液としての使用のための４％クエン酸三ナトリウム溶液 |
| IL302714B1 (en) | 2017-11-08 | 2026-01-01 | Taris Biomedical Llc | Methods for treating and maintaining bladder cancer using gemcitabine |
| CN112839653A (zh) | 2018-08-01 | 2021-05-25 | 塔里斯生物医药公司 | 使用曲司氯铵治疗膀胱过度活动症的方法 |
| CN109589491B (zh) * | 2019-01-29 | 2024-01-09 | 上海安翰医疗技术有限公司 | 自动给药装置 |
| US12383700B2 (en) | 2019-06-13 | 2025-08-12 | Hollister Incorporated | Reusable urinary catheter products |
| EP4628107A3 (en) | 2019-06-25 | 2025-12-17 | Hollister Incorporated | Reusable urinary catheter products |
| AU2021354328B2 (en) * | 2020-09-30 | 2025-06-05 | Modibodi Australia Pty Ltd | A fabric insert |
| WO2025147450A1 (en) * | 2024-01-02 | 2025-07-10 | Manta Pharma Llc | Implantable device for adjustable dose using pressure sensor for piston displacement monitoring |
| EP4684818A1 (en) * | 2024-07-23 | 2026-01-28 | Manta MedTech LLC | Implantable device actuated using motor and osmotic motor |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2155889B (en) * | 1984-03-21 | 1988-03-02 | Alza Corp | Dispenser-capsule |
| MY125870A (en) * | 1997-07-25 | 2006-08-30 | Alza Corp | Osmotic delivery system flow modulator apparatus and method |
| US6436091B1 (en) * | 1999-11-16 | 2002-08-20 | Microsolutions, Inc. | Methods and implantable devices and systems for long term delivery of a pharmaceutical agent |
| US8133501B2 (en) * | 2002-02-08 | 2012-03-13 | Boston Scientific Scimed, Inc. | Implantable or insertable medical devices for controlled drug delivery |
| DE602004012081T2 (de) * | 2003-03-31 | 2009-03-19 | Intarcia Therapeutics, Inc., Emeryville | Osmotische pumpe mit mitteln zum ableiten des innendrucks |
| US8257963B2 (en) * | 2007-06-01 | 2012-09-04 | Depuy Mitek, Inc. | Chondrocyte container and method of use |
| JP5265359B2 (ja) | 2005-08-11 | 2013-08-14 | マサチューセッツ インスティテュート オブ テクノロジー | 膀胱内薬物送達デバイスおよび方法 |
| TW200927141A (en) * | 2007-11-22 | 2009-07-01 | Bayer Schering Pharma Oy | Vaginal delivery system |
| US9586035B2 (en) * | 2007-12-11 | 2017-03-07 | Massachusetts Institute Of Technology | Implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens |
| EA201170297A1 (ru) * | 2008-08-09 | 2011-08-30 | Массачусетс Инститьют Оф Текнолоджи | Имплантируемое устройство для доставки лекарственных средств и способ лечения мужской мочеполовой системы и окружающих тканей |
| CN102470237A (zh) | 2009-06-26 | 2012-05-23 | 塔里斯生物医药公司 | 用于可植入药物递送装置的固体药物片剂 |
| US8721621B2 (en) | 2009-09-10 | 2014-05-13 | Taris Biomedical, Inc. | Systems and methods for deploying devices to genitourinary sites |
| US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
| PL3884988T3 (pl) | 2009-12-17 | 2025-09-08 | Taris Biomedical Llc | Urządzenie implantowalne z tolerancją wewnątrzpęcherzową |
| WO2011112723A2 (en) * | 2010-03-09 | 2011-09-15 | Board Of Regents Of The University Of Texas System | Electro-osmotic pumps, systems, methods, and compositions |
| DK2600800T3 (da) | 2010-08-05 | 2020-11-16 | Taris Biomedical Llc | Indretning til lægemiddellevering i en ureterstent og kit dertil |
| US9457176B2 (en) | 2010-10-06 | 2016-10-04 | Taris Biomedical Llc | Implantable drug delivery device with bladder retention feature |
| JP5945544B2 (ja) * | 2010-10-06 | 2016-07-05 | タリス バイオメディカル エルエルシー | 時間選択的に生体吸収可能または崩壊可能な薬剤送達システムおよび方法 |
| US9114111B2 (en) | 2011-01-10 | 2015-08-25 | Allergan, Inc. | Methods for sustained treatment of bladder pain and irritative voiding |
| TWI615155B (zh) * | 2011-11-01 | 2018-02-21 | 拜耳股份有限公司 | 滲透活性的陰道遞送系統 |
| PT2968880T (pt) | 2013-03-15 | 2025-07-07 | Taris Biomedical Llc | Dispositivos de aplicação de fármaco com componente permeável a fármaco |
-
2014
- 2014-11-05 BR BR112016010103A patent/BR112016010103A8/pt not_active IP Right Cessation
- 2014-11-05 EP EP14802296.5A patent/EP3065807A1/en not_active Withdrawn
- 2014-11-05 WO PCT/US2014/064063 patent/WO2015069723A1/en not_active Ceased
- 2014-11-05 CN CN201480063520.5A patent/CN105792880A/zh active Pending
- 2014-11-05 CA CA2929554A patent/CA2929554A1/en not_active Abandoned
- 2014-11-05 KR KR1020167014800A patent/KR20160083061A/ko not_active Withdrawn
- 2014-11-05 JP JP2016552464A patent/JP2017500171A/ja active Pending
- 2014-11-05 US US15/033,692 patent/US20160279399A1/en not_active Abandoned
- 2014-11-05 RU RU2016120199A patent/RU2016120199A/ru not_active Application Discontinuation
-
2016
- 2016-05-03 IL IL245445A patent/IL245445A0/en unknown
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