JP2020503013A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020503013A5 JP2020503013A5 JP2019531740A JP2019531740A JP2020503013A5 JP 2020503013 A5 JP2020503013 A5 JP 2020503013A5 JP 2019531740 A JP2019531740 A JP 2019531740A JP 2019531740 A JP2019531740 A JP 2019531740A JP 2020503013 A5 JP2020503013 A5 JP 2020503013A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- seq
- composition according
- antibody
- adm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023009286A JP2023052614A (ja) | 2016-12-16 | 2023-01-25 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
| JP2024143320A JP2024170454A (ja) | 2016-12-16 | 2024-08-23 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16204847 | 2016-12-16 | ||
| EP16204847.4 | 2016-12-16 | ||
| EP16206305.1 | 2016-12-22 | ||
| EP16206305.1A EP3339324A1 (en) | 2016-12-22 | 2016-12-22 | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in intervention and therapy of congestion in a patient in need thereof |
| EP17197176 | 2017-10-18 | ||
| EP17197176.5 | 2017-10-18 | ||
| PCT/EP2017/083311 WO2018109228A1 (en) | 2016-12-16 | 2017-12-18 | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in intervention and therapy of congestion in a patient in need thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023009286A Division JP2023052614A (ja) | 2016-12-16 | 2023-01-25 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020503013A JP2020503013A (ja) | 2020-01-30 |
| JP2020503013A5 true JP2020503013A5 (https=) | 2021-02-04 |
| JP7727371B2 JP7727371B2 (ja) | 2025-08-21 |
Family
ID=61148166
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019531740A Active JP7727371B2 (ja) | 2016-12-16 | 2017-12-18 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
| JP2023009286A Pending JP2023052614A (ja) | 2016-12-16 | 2023-01-25 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
| JP2024143320A Pending JP2024170454A (ja) | 2016-12-16 | 2024-08-23 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023009286A Pending JP2023052614A (ja) | 2016-12-16 | 2023-01-25 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
| JP2024143320A Pending JP2024170454A (ja) | 2016-12-16 | 2024-08-23 | うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20200299372A1 (https=) |
| EP (1) | EP3555130A1 (https=) |
| JP (3) | JP7727371B2 (https=) |
| KR (3) | KR20240033285A (https=) |
| CN (2) | CN110167962B (https=) |
| AU (2) | AU2017375049B2 (https=) |
| BR (1) | BR112019011713A2 (https=) |
| CA (1) | CA3046850A1 (https=) |
| IL (2) | IL322765A (https=) |
| MX (1) | MX2019007107A (https=) |
| MY (1) | MY208219A (https=) |
| RU (1) | RU2762059C2 (https=) |
| WO (1) | WO2018109228A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20241795T1 (hr) * | 2017-09-25 | 2025-03-14 | Adrenomed Ag | Anti-adrenomedulin (adm) – vezujući entitet za uporabu u terapiji ili prevenciji simptoma bolesti |
| EP3871689A1 (en) * | 2020-02-26 | 2021-09-01 | sphingotec GmbH | Anti-adm-antibodies binding to the free n-terminus for accelerated transition of adm-gly to bio-adm in patients with adm-gly/ bio-adm ratio above a threshold and combination with vitamin c |
| CN115244080A (zh) * | 2020-02-27 | 2022-10-25 | 艾德里诺医药公司 | 用于治疗或预防休克的抗肾上腺髓质素(ADM)抗体或抗ADM抗体片段或抗ADM非Ig支架 |
| AU2021238591A1 (en) * | 2020-03-16 | 2022-11-17 | Adrenomed Ag | Pro-Adrenomedullin or fragment thereof in patients infected with Corona virus and treatments with binder against adrenomedullin |
| CA3254142A1 (en) | 2022-03-15 | 2023-09-21 | Adrenomed Ag | STABLE AQUEOUS FORMULATION OF AN ANTI-ADRENOMEDULLIN (ADM) ANTIBODY OR AN ANTI-ADM ANTIBODY FRAGMENT |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| AU634716B2 (en) | 1988-08-01 | 1993-03-04 | Ciba Corning Diagnostics Corp. | Method for detection of an analyte using acridinium esters and liposomes |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| DE69120146T2 (de) | 1990-01-12 | 1996-12-12 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| DK0585287T3 (da) | 1990-07-10 | 2000-04-17 | Cambridge Antibody Tech | Fremgangsmåde til fremstilling af specifikke bindingsparelementer |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| WO1993012227A1 (en) | 1991-12-17 | 1993-06-24 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| JP2774769B2 (ja) | 1993-04-26 | 1998-07-09 | 賢治 寒川 | アドレノメデュリン |
| US6818418B1 (en) | 1998-12-10 | 2004-11-16 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| AU2002323501C1 (en) | 2001-08-30 | 2010-04-29 | Biorexis Technology, Inc | Modified transferrin fusion proteins |
| ES2348230T3 (es) | 2002-06-07 | 2010-12-01 | Dyax Corp. | Prevención y reducción de la isquemia. |
| DE10316583A1 (de) | 2003-04-10 | 2004-10-28 | B.R.A.H.M.S Aktiengesellschaft | Bestimmung eines midregionalen Proadrenomedullin-Teilpeptids in biologischen Flüssigkeiten zu diagnostischen Zwecken, sowie Immunoassays für die Durchführung einer solchen Bestimmung |
| EP1620734A1 (en) | 2003-04-25 | 2006-02-01 | Genova Ltd. | Secreted polypeptide species reduced cardiovascular disorders |
| US20050164301A1 (en) | 2003-10-24 | 2005-07-28 | Avidia Research Institute | LDL receptor class A and EGF domain monomers and multimers |
| US20100028995A1 (en) | 2004-02-23 | 2010-02-04 | Anaphore, Inc. | Tetranectin Trimerizing Polypeptides |
| US20070280886A1 (en) | 2004-09-09 | 2007-12-06 | Bayer Healthcare Ag | Diagnostics and Therapeutics for Diseases Associated with Adrenomedullin Receptor (Amdr) |
| AU2005287557B2 (en) | 2004-09-21 | 2011-10-13 | Biontech Ag | Use of microproteins as tryptase inhibitors |
| ES2373832T3 (es) | 2007-12-19 | 2012-02-09 | Affibody Ab | Polipéptido derivado de proteína a y capaz de unirse a pdgf. |
| US20110301332A1 (en) * | 2008-07-01 | 2011-12-08 | Cephalon Australia (Vic) Pty Ltd. | Anti-pamp therapeutic antibodies |
| BRPI0921469B1 (pt) | 2008-11-03 | 2022-01-18 | Molecular Partners Ag | Proteínas de ligação que inibem a interação com o receptor de vegf-a, composição farmacêutica |
| MX2012002428A (es) | 2009-08-27 | 2012-09-12 | Covagen Ag | Compuestos de union il-17 y usos medicos de los mismos. |
| RU2553333C2 (ru) | 2009-12-14 | 2015-06-10 | Сцил Протеинс Гмбх | Способ идентификации гетеромультимерных модифицированных убиквитиновых белков со способностью связываться с лигандами |
| PL2580236T3 (pl) | 2010-06-08 | 2019-09-30 | Pieris Pharmaceuticals Gmbh | Muteiny lipokaliny łez wiążące IL-4 R alfa |
| CN103119446B (zh) * | 2010-06-18 | 2016-03-30 | B.R.A.H.M.S有限公司 | 预测癌症发生的生物标志物 |
| IL283215B2 (en) * | 2011-11-16 | 2024-05-01 | Adrenomed Ag | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment and pharmaceutical compostions comprising the same |
| ES2494190T3 (es) * | 2011-11-16 | 2014-09-15 | Adrenomed Ag | Anticuerpo anti-adrenomedulina (ADM) o fragmento de anticuerpo anti-ADM o andamiaje proteico sin Ig anti-ADM para reducir el riesgo de mortalidad en un paciente que padece una enfermedad crónica o aguda o un estado agudo |
| LT3553084T (lt) * | 2011-11-16 | 2023-03-10 | Adrenomed Ag | Anti-adrenomedulino (adm) antikūnas arba anti-adm antikūno fragmentas, arba anti-adm ne-ig karkasas, skirtas organų funkcijos sutrikimo arba organų nepakankamumo profilaktikai arba sumažinimui paciento, sergančio lėtine arba ūmine liga arba esančio ūminės būklės, organizme |
| EP2780370B1 (en) * | 2011-11-16 | 2019-09-25 | AdrenoMed AG | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in therapy of an acute disease or acute condition of a patient for stabilizing the circulation |
| HRP20170427T1 (hr) * | 2011-11-16 | 2017-06-16 | Sphingotec Gmbh | Testovi na adrenomedulin i postupci određivanja zrelog adrenomedulina |
| PT2780371T (pt) * | 2011-11-16 | 2019-01-30 | Adrenomed Ag | Anticorpo anti-adrenomedulina (adm) ou fragmento de anticorpo anti-adm ou uma estrutura não ig anti-adm para a regulação do equilíbrio de fluidos num doente com uma doença aguda ou crónica |
-
2017
- 2017-12-18 JP JP2019531740A patent/JP7727371B2/ja active Active
- 2017-12-18 MX MX2019007107A patent/MX2019007107A/es unknown
- 2017-12-18 KR KR1020247006366A patent/KR20240033285A/ko not_active Ceased
- 2017-12-18 MY MYPI2019003407A patent/MY208219A/en unknown
- 2017-12-18 RU RU2019122135A patent/RU2762059C2/ru active
- 2017-12-18 CN CN201780077335.5A patent/CN110167962B/zh active Active
- 2017-12-18 US US16/469,738 patent/US20200299372A1/en not_active Abandoned
- 2017-12-18 KR KR1020197020162A patent/KR20190120174A/ko not_active Ceased
- 2017-12-18 KR KR1020257017044A patent/KR20250084231A/ko active Pending
- 2017-12-18 AU AU2017375049A patent/AU2017375049B2/en active Active
- 2017-12-18 CA CA3046850A patent/CA3046850A1/en active Pending
- 2017-12-18 WO PCT/EP2017/083311 patent/WO2018109228A1/en not_active Ceased
- 2017-12-18 EP EP17837953.3A patent/EP3555130A1/en active Pending
- 2017-12-18 CN CN202410627213.0A patent/CN118767128A/zh active Pending
- 2017-12-18 IL IL322765A patent/IL322765A/en unknown
- 2017-12-18 BR BR112019011713-0A patent/BR112019011713A2/pt unknown
-
2019
- 2019-06-12 IL IL267282A patent/IL267282A/en unknown
-
2021
- 2021-06-04 US US17/339,221 patent/US20220041703A1/en active Pending
-
2023
- 2023-01-25 JP JP2023009286A patent/JP2023052614A/ja active Pending
-
2024
- 2024-08-23 JP JP2024143320A patent/JP2024170454A/ja active Pending
-
2025
- 2025-04-29 AU AU2025202983A patent/AU2025202983A1/en active Pending