JP2020512344A5 - - Google Patents
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- JP2020512344A5 JP2020512344A5 JP2019552991A JP2019552991A JP2020512344A5 JP 2020512344 A5 JP2020512344 A5 JP 2020512344A5 JP 2019552991 A JP2019552991 A JP 2019552991A JP 2019552991 A JP2019552991 A JP 2019552991A JP 2020512344 A5 JP2020512344 A5 JP 2020512344A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- variable region
- chain variable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762476940P | 2017-03-27 | 2017-03-27 | |
| US62/476,940 | 2017-03-27 | ||
| PCT/US2018/024296 WO2018183173A1 (en) | 2017-03-27 | 2018-03-26 | Anti il-36r antibodies combination therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020512344A JP2020512344A (ja) | 2020-04-23 |
| JP2020512344A5 true JP2020512344A5 (https=) | 2021-04-30 |
Family
ID=62002399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019552991A Pending JP2020512344A (ja) | 2017-03-27 | 2018-03-26 | 抗ｉｌ−３６ｒ抗体併用治療 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20180273627A1 (https=) |
| EP (1) | EP3601350A1 (https=) |
| JP (1) | JP2020512344A (https=) |
| CN (1) | CN110461877A (https=) |
| WO (1) | WO2018183173A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115925932A (zh) | 2015-04-15 | 2023-04-07 | 安奈普泰斯生物有限公司 | 针对白细胞介素36受体（il-36r）的抗体 |
| JP2021517577A (ja) * | 2018-03-14 | 2021-07-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 炎症性腸疾患の処置のための抗ｉｌ−３６ｒ抗体の使用 |
| BR112020016738A2 (pt) * | 2018-03-14 | 2020-12-15 | Boehringer Ingelheim International Gmbh | Uso de anticorpos anti-il-36r para o tratamento de psoríase pustular generalizada |
| AU2019306217B2 (en) | 2018-07-16 | 2024-01-25 | Regeneron Pharmaceuticals, Inc. | Anti-IL36R antibodies |
| IL286100B2 (en) | 2019-03-08 | 2024-12-01 | Boehringer Ingelheim Int | Anti-il-36r antibody formulations |
| JP7778567B2 (ja) * | 2019-04-17 | 2025-12-02 | ミレニアム ファーマシューティカルズ， インコーポレイテッド | α４β７阻害薬及びＩＬ－２３阻害薬の併用療法 |
| CN111848780A (zh) * | 2019-04-24 | 2020-10-30 | 华东师范大学 | 一种IL-36的可溶性受体sIL-36R及其应用 |
| AR120913A1 (es) * | 2019-12-27 | 2022-03-30 | Teijin Pharma Ltd | Anticuerpo que inhibe específicamente la señalización de il-36r |
| WO2021259880A1 (en) * | 2020-06-22 | 2021-12-30 | Almirall, S.A. | Anti-il-36 antibodies and methods of use thereof |
| BR112022026999A2 (pt) | 2020-07-17 | 2023-01-24 | Boehringer Ingelheim Int | Anticorpos anti-il-36r para tratamento de dermatoses neutrofílicas |
| WO2022026829A1 (en) | 2020-07-30 | 2022-02-03 | Anaptysbio, Inc. | Anti-interleukin 36 receptor (il-36r) therapy for skin toxicity |
| EP4188441A1 (en) | 2020-07-30 | 2023-06-07 | AnaptysBio, Inc. | Anti-interleukin 36 receptor (il-36r) therapy for ichthyosis |
| CN112094349B (zh) * | 2020-11-04 | 2021-02-09 | 上海华奥泰生物药业股份有限公司 | 靶向于白介素36r的抗体及其制备方法和应用 |
| WO2022150644A1 (en) | 2021-01-08 | 2022-07-14 | Anaptysbio, Inc. | Anti-interleukin 36 receptor (il-36r) therapy for acne |
| WO2022150642A1 (en) | 2021-01-08 | 2022-07-14 | Anaptysbio, Inc. | Anti-interleukin 36 receptor (il-36r) therapy for hidradenitis suppurativa |
| CN114907477A (zh) * | 2021-02-08 | 2022-08-16 | 上海普铭生物科技有限公司 | 抗人il-36r抗体及其应用 |
| CA3209006A1 (en) * | 2021-03-04 | 2022-09-09 | Boehringer Ingelheim International Gmbh | Methods for the treatment of gpp |
| JP2024521967A (ja) * | 2021-06-18 | 2024-06-04 | チア タイ ティエンチン ファーマシューティカル グループ カンパニー リミテッド | 抗ｉｌ－３６ｒ抗体及びその使用 |
| TW202323293A (zh) * | 2021-10-29 | 2023-06-16 | 新加坡商創響私人有限公司 | 新型抗ｉｌ－３６ｒ抗體 |
| CN115724975A (zh) | 2022-10-20 | 2023-03-03 | 江苏荃信生物医药股份有限公司 | 抗人白介素36受体单克隆抗体及其应用 |
| CN117357474B (zh) * | 2022-12-19 | 2024-12-03 | 江苏荃信生物医药股份有限公司 | 抗人白介素36受体单克隆抗体及液体制剂 |
| JP2026506716A (ja) * | 2023-02-21 | 2026-02-25 | 江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司 | Ｉｌ－３６ｒ結合タンパク質及びその医薬的使用 |
| WO2024251927A2 (en) * | 2023-06-09 | 2024-12-12 | Boehringer Ingelheim International Gmbh | Methods for the treatment and prevention of gpp |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4318980A (en) | 1978-04-10 | 1982-03-09 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a cycling reactant as label |
| JPS6023084B2 (ja) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| WO1981001145A1 (en) | 1979-10-18 | 1981-04-30 | Univ Illinois | Hydrolytic enzyme-activatible pro-drugs |
| US4419446A (en) | 1980-12-31 | 1983-12-06 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant DNA process utilizing a papilloma virus DNA as a vector |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| NZ201705A (en) | 1981-08-31 | 1986-03-14 | Genentech Inc | Recombinant dna method for production of hepatitis b surface antigen in yeast |
| US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4741900A (en) | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
| US4601978A (en) | 1982-11-24 | 1986-07-22 | The Regents Of The University Of California | Mammalian metallothionein promoter system |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DD266710A3 (de) | 1983-06-06 | 1989-04-12 | Ve Forschungszentrum Biotechnologie | Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| US4965199A (en) | 1984-04-20 | 1990-10-23 | Genentech, Inc. | Preparation of functional human factor VIII in mammalian cells using methotrexate based selection |
| US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
| US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
| EP0206448B1 (en) | 1985-06-19 | 1990-11-14 | Ajinomoto Co., Inc. | Hemoglobin combined with a poly(alkylene oxide) |
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| GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
| US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| GB8705477D0 (en) | 1987-03-09 | 1987-04-15 | Carlton Med Prod | Drug delivery systems |
| US4975278A (en) | 1988-02-26 | 1990-12-04 | Bristol-Myers Company | Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells |
| ATE135397T1 (de) | 1988-09-23 | 1996-03-15 | Cetus Oncology Corp | Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte |
| FR2646437B1 (fr) | 1989-04-28 | 1991-08-30 | Transgene Sa | Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant |
| EP0402226A1 (en) | 1989-06-06 | 1990-12-12 | Institut National De La Recherche Agronomique | Transformation vectors for yeast yarrowia |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| AU687755B2 (en) | 1992-08-21 | 1998-03-05 | Genentech Inc. | Method for treating an LFA-1-mediated disorder |
| DK0752248T3 (da) | 1992-11-13 | 2000-11-13 | Idec Pharma Corp | Terapeutisk anvendelse af kimæriske og radioaktivt mærkede antistoffer mod humant B-lymfocytbegrænset differentieringsantig |
| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| US5888809A (en) | 1997-05-01 | 1999-03-30 | Icos Corporation | Hamster EF-1α transcriptional regulatory DNA |
| SI3536710T1 (sl) * | 2011-11-16 | 2026-04-30 | Boehringer Ingelheim International Gmbh | Protitelesa proti IL-36R |
| CN115925932A (zh) * | 2015-04-15 | 2023-04-07 | 安奈普泰斯生物有限公司 | 针对白细胞介素36受体（il-36r）的抗体 |
-
2018
- 2018-03-26 JP JP2019552991A patent/JP2020512344A/ja active Pending
- 2018-03-26 EP EP18718268.8A patent/EP3601350A1/en not_active Withdrawn
- 2018-03-26 WO PCT/US2018/024296 patent/WO2018183173A1/en not_active Ceased
- 2018-03-26 US US15/935,519 patent/US20180273627A1/en not_active Abandoned
- 2018-03-26 CN CN201880022517.7A patent/CN110461877A/zh active Pending
-
2022
- 2022-09-07 US US17/930,072 patent/US20230044739A1/en not_active Abandoned
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