JP2019510739A5 - - Google Patents
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- Publication number
- JP2019510739A5 JP2019510739A5 JP2018540415A JP2018540415A JP2019510739A5 JP 2019510739 A5 JP2019510739 A5 JP 2019510739A5 JP 2018540415 A JP2018540415 A JP 2018540415A JP 2018540415 A JP2018540415 A JP 2018540415A JP 2019510739 A5 JP2019510739 A5 JP 2019510739A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- composition according
- mammal
- gfral
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2016/074809 WO2017147742A1 (en) | 2016-02-29 | 2016-02-29 | Gfral receptor therapies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019510739A JP2019510739A (ja) | 2019-04-18 |
| JP2019510739A5 true JP2019510739A5 (https=) | 2019-05-30 |
Family
ID=59742416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018540415A Pending JP2019510739A (ja) | 2016-02-29 | 2016-02-29 | Ｇｆｒａｌ受容体療法 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP3423094A4 (https=) |
| JP (1) | JP2019510739A (https=) |
| CN (1) | CN108697795A (https=) |
| WO (1) | WO2017147742A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103533951B (zh) | 2011-04-08 | 2017-04-19 | 安姆根有限公司 | 使用生长分化因子15(gdf‑15)治疗或改善代谢障碍的方法 |
| US10588980B2 (en) | 2014-06-23 | 2020-03-17 | Novartis Ag | Fatty acids and their use in conjugation to biomolecules |
| US20170299608A1 (en) * | 2016-03-04 | 2017-10-19 | Ngm Biopharmaceuticals, Inc. | Compositions and methods for modulating body weight |
| PE20190126A1 (es) | 2016-03-31 | 2019-01-17 | Ngm Biopharmaceuticals Inc | Proteinas de union y metodos de uso de las mismas |
| EP3526346A1 (en) * | 2016-10-12 | 2019-08-21 | Janssen Biotech, Inc. | Methods for screening for modulators of gdf15-like biological activity |
| TWI724392B (zh) | 2018-04-06 | 2021-04-11 | 美商美國禮來大藥廠 | 生長分化因子15促效劑化合物及其使用方法 |
| EP3870211B1 (en) | 2018-10-22 | 2025-01-08 | Janssen Sciences Ireland Unlimited Company | Glucagon like peptide 1 (glp1)-growth differentiation factor 15 (gdf15) fusion proteins and uses thereof |
| US12544427B2 (en) | 2019-10-04 | 2026-02-10 | Amgen Inc. | Use of GDF15 for treating cardiometabolic syndrome and other conditions |
| JP2022552655A (ja) | 2019-10-07 | 2022-12-19 | キャリーオペ，インク． | Ｇｐｒ１１９アゴニスト |
| IL295825A (en) | 2020-02-28 | 2022-10-01 | Kallyope Inc | gpr40 agonists |
| WO2021236617A1 (en) | 2020-05-19 | 2021-11-25 | Kallyope, Inc. | Ampk activators |
| WO2021246773A1 (ko) * | 2020-06-04 | 2021-12-09 | 재단법인대구경북과학기술원 | Gfral 길항 항체 및 이의 용도 |
| CA3183575A1 (en) | 2020-06-26 | 2021-12-30 | Iyassu Sebhat | Ampk activators |
| CA3215737A1 (en) * | 2021-03-31 | 2022-10-06 | Cambridge Enterprise Limited | Therapeutic inhibitors of gdf15 signalling |
| US20240368286A1 (en) * | 2021-06-30 | 2024-11-07 | Shanghai Jmt-Bio Technology Co., Ltd. | Anti-gfral antibody and application thereof |
| CN118580334A (zh) * | 2023-03-03 | 2024-09-03 | 北京志道生物科技有限公司 | 一种多肽分子 |
| IT202300006387A1 (it) * | 2023-03-31 | 2024-10-01 | Univ Degli Studi Roma La Sapienza | Inibitore del recettore gfral per uso nel trattamento della sclerosi laterale amiotrofica |
| CN116444667B (zh) * | 2023-06-13 | 2023-09-01 | 上海驯鹿生物技术有限公司 | 一种靶向gdf15的全人源抗体及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1506215B1 (en) * | 2002-03-05 | 2016-11-30 | Genentech, Inc. | Novel polypeptides having sequence similarity to gdnfr and nucleic acids encoding the same |
| US20100278843A1 (en) * | 2007-08-16 | 2010-11-04 | St. Vincent's Hospital Sydney Limited | Agents and methods for modulating macrophage inhibitory cytokine (mic-1) activity |
| CN103533951B (zh) * | 2011-04-08 | 2017-04-19 | 安姆根有限公司 | 使用生长分化因子15(gdf‑15)治疗或改善代谢障碍的方法 |
| CN102321173B (zh) * | 2011-08-12 | 2013-04-03 | 中国医学科学院肿瘤研究所 | 人源化巨噬细胞抑制因子1单克隆抗体及其应用 |
| JO3462B1 (ar) * | 2012-08-22 | 2020-07-05 | Regeneron Pharma | أجسام مضادة بشرية تجاه gfr?3 وطرق لاستخدامها |
| CA2896076C (en) * | 2012-12-21 | 2022-12-06 | Aveo Pharmaceuticals, Inc. | Anti-gdf15 antibodies |
| WO2017121865A1 (en) * | 2016-01-15 | 2017-07-20 | Novo Nordisk A/S | Mic-1 receptor and uses thereof |
-
2016
- 2016-02-29 CN CN201680082844.2A patent/CN108697795A/zh active Pending
- 2016-02-29 JP JP2018540415A patent/JP2019510739A/ja active Pending
- 2016-02-29 EP EP16891935.5A patent/EP3423094A4/en not_active Withdrawn
- 2016-02-29 WO PCT/CN2016/074809 patent/WO2017147742A1/en not_active Ceased
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