JP2020502280A5 - - Google Patents
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- Publication number
- JP2020502280A5 JP2020502280A5 JP2019554488A JP2019554488A JP2020502280A5 JP 2020502280 A5 JP2020502280 A5 JP 2020502280A5 JP 2019554488 A JP2019554488 A JP 2019554488A JP 2019554488 A JP2019554488 A JP 2019554488A JP 2020502280 A5 JP2020502280 A5 JP 2020502280A5
- Authority
- JP
- Japan
- Prior art keywords
- flocculant
- liquid
- produce
- liquid mixture
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007788 liquid Substances 0.000 claims description 24
- 239000000203 mixture Substances 0.000 claims description 13
- 239000000243 solution Substances 0.000 claims description 10
- 239000007864 aqueous solution Substances 0.000 claims description 8
- 239000013067 intermediate product Substances 0.000 claims description 8
- 150000001875 compounds Chemical class 0.000 claims description 7
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 claims description 6
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 6
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 4
- 239000007795 chemical reaction product Substances 0.000 claims description 4
- XTAZYLNFDRKIHJ-UHFFFAOYSA-N n,n-dioctyloctan-1-amine Chemical compound CCCCCCCCN(CCCCCCCC)CCCCCCCC XTAZYLNFDRKIHJ-UHFFFAOYSA-N 0.000 claims description 4
- 239000001301 oxygen Substances 0.000 claims description 4
- 229910052760 oxygen Inorganic materials 0.000 claims description 4
- LLLXGCKPGCZALY-UHFFFAOYSA-N 2-butoxyethyl 4-methylbenzenesulfonate Chemical compound CCCCOCCOS(=O)(=O)C1=CC=C(C)C=C1 LLLXGCKPGCZALY-UHFFFAOYSA-N 0.000 claims description 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 3
- -1 anion salt Chemical class 0.000 claims description 3
- 229910052786 argon Inorganic materials 0.000 claims description 3
- 239000001913 cellulose Substances 0.000 claims description 3
- 238000005119 centrifugation Methods 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 239000011261 inert gas Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 229910052757 nitrogen Inorganic materials 0.000 claims description 3
- 235000019814 powdered cellulose Nutrition 0.000 claims description 3
- 229920003124 powdered cellulose Polymers 0.000 claims description 3
- 238000004062 sedimentation Methods 0.000 claims description 3
- 150000001450 anions Chemical group 0.000 claims description 2
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims 3
- 239000003880 polar aprotic solvent Substances 0.000 claims 1
- SLINHMUFWFWBMU-UHFFFAOYSA-N Triisopropanolamine Chemical compound CC(O)CN(CC(C)O)CC(C)O SLINHMUFWFWBMU-UHFFFAOYSA-N 0.000 description 1
- 239000000701 coagulant Substances 0.000 description 1
- COFKFSSWMQHKMD-UHFFFAOYSA-N n,n-didecyldecan-1-amine Chemical compound CCCCCCCCCCN(CCCCCCCCCC)CCCCCCCCCC COFKFSSWMQHKMD-UHFFFAOYSA-N 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- SWZDQOUHBYYPJD-UHFFFAOYSA-N tridodecylamine Chemical compound CCCCCCCCCCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC SWZDQOUHBYYPJD-UHFFFAOYSA-N 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662436743P | 2016-12-20 | 2016-12-20 | |
| US62/436,743 | 2016-12-20 | ||
| PCT/US2017/067263 WO2018118891A1 (en) | 2016-12-20 | 2017-12-19 | Methods of making substituted porphyrin pharmaceutical compounds and compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020502280A JP2020502280A (ja) | 2020-01-23 |
| JP2020502280A5 true JP2020502280A5 (enExample) | 2021-02-04 |
Family
ID=62628012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019554488A Pending JP2020502280A (ja) | 2016-12-20 | 2017-12-19 | 置換ポルフィリン医薬化合物及び組成物を製造する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20190330220A1 (enExample) |
| EP (1) | EP3558902A4 (enExample) |
| JP (1) | JP2020502280A (enExample) |
| KR (1) | KR20190098211A (enExample) |
| CN (1) | CN110291060A (enExample) |
| CA (1) | CA3046357A1 (enExample) |
| MX (1) | MX2019007301A (enExample) |
| WO (1) | WO2018118891A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018187411A1 (en) * | 2017-04-04 | 2018-10-11 | Biomimetix Jv, Llc | Methods, compositions, and kits for treating and/or preventing a side effect associated with radiation and/or chemotherapy exposure |
| WO2019067523A1 (en) * | 2017-09-29 | 2019-04-04 | Duke University | FLUOROSUBSTITUTED PORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THEM AND METHODS OF PREPARATION AND USE THEREOF |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6127356A (en) * | 1993-10-15 | 2000-10-03 | Duke University | Oxidant scavengers |
| ATE552260T1 (de) * | 1999-01-25 | 2012-04-15 | Nat Jewish Health | Substituierte porphyrine und deren therapeutische verwendung |
| EP1513537A4 (en) * | 2002-06-07 | 2006-09-06 | Univ Duke | Substituted porphyrins |
| US7807825B2 (en) * | 2004-02-09 | 2010-10-05 | Duke University | Substituted porphyrins |
| US20110275606A1 (en) * | 2009-01-07 | 2011-11-10 | Duke University | Substituted porphyrins |
| WO2010138633A1 (en) * | 2009-05-26 | 2010-12-02 | Duke University | Method of providing neuroprotection using substituted porphyrins |
| US10080759B2 (en) * | 2014-01-22 | 2018-09-25 | Duke University | Methods of treating pruritus |
-
2017
- 2017-12-19 KR KR1020197021201A patent/KR20190098211A/ko not_active Ceased
- 2017-12-19 US US16/468,911 patent/US20190330220A1/en not_active Abandoned
- 2017-12-19 CN CN201780086851.4A patent/CN110291060A/zh active Pending
- 2017-12-19 JP JP2019554488A patent/JP2020502280A/ja active Pending
- 2017-12-19 EP EP17882736.6A patent/EP3558902A4/en not_active Withdrawn
- 2017-12-19 MX MX2019007301A patent/MX2019007301A/es unknown
- 2017-12-19 CA CA3046357A patent/CA3046357A1/en not_active Abandoned
- 2017-12-19 WO PCT/US2017/067263 patent/WO2018118891A1/en not_active Ceased
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