|
PL3429596T3
(pl)
|
2016-03-18 |
2022-12-19 |
Immune Sensor, Llc |
Cykliczne związki dinukleotydowe i sposoby stosowania
|
|
EP3507367A4
(en)
|
2016-07-05 |
2020-03-25 |
Aduro BioTech, Inc. |
CYCLIC DINUCLEOTID COMPOUNDS WITH INCLUDED NUCLEIC ACIDS AND USES THEREOF
|
|
CN110023495A
(zh)
|
2016-10-14 |
2019-07-16 |
精密生物科学公司 |
对乙肝病毒基因组中的识别序列特异性的工程化大范围核酸酶
|
|
JOP20170192A1
(ar)
|
2016-12-01 |
2019-01-30 |
Takeda Pharmaceuticals Co |
داي نوكليوتيد حلقي
|
|
WO2018138684A1
(en)
*
|
2017-01-27 |
2018-08-02 |
Janssen Biotech, Inc. |
Cyclic dinucleotides as sting agonists
|
|
EP3573718B1
(en)
*
|
2017-01-27 |
2022-06-01 |
Janssen Biotech, Inc. |
Cyclic dinucleotides as sting agonists
|
|
US20200055883A1
(en)
|
2017-02-17 |
2020-02-20 |
Eisai R&D Management Co., Ltd. |
Cyclic di-nucleotides derivative for the treatment of cancer
|
|
US11773132B2
(en)
*
|
2017-08-30 |
2023-10-03 |
Beijing Xuanyi Pharmasciences Co., Ltd. |
Cyclic di-nucleotides as stimulator of interferon genes modulators
|
|
WO2019084060A1
(en)
|
2017-10-24 |
2019-05-02 |
Silverback Therapeutics, Inc. |
CONJUGATES AND METHODS OF USE FOR THE SELECTIVE DELIVERY OF IMMUNOMODULATORY AGENTS
|
|
JP7195317B2
(ja)
|
2017-11-10 |
2022-12-23 |
武田薬品工業株式会社 |
Ｓｔｉｎｇ調節剤化合物、ならびに製造及び使用する方法
|
|
WO2019123340A1
(en)
|
2017-12-20 |
2019-06-27 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
|
|
CA3084582A1
(en)
|
2017-12-20 |
2019-06-27 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
|
|
US10836769B2
(en)
|
2018-02-26 |
2020-11-17 |
Gilead Sciences, Inc. |
Substituted pyrrolizine compounds and uses thereof
|
|
EP3774883A1
(en)
|
2018-04-05 |
2021-02-17 |
Gilead Sciences, Inc. |
Antibodies and fragments thereof that bind hepatitis b virus protein x
|
|
TWI818007B
(zh)
|
2018-04-06 |
2023-10-11 |
捷克科學院有機化學與生物化學研究所 |
2'3'-環二核苷酸
|
|
TW202005654A
(zh)
|
2018-04-06 |
2020-02-01 |
捷克科學院有機化學與生物化學研究所 |
２，２，─環二核苷酸
|
|
TWI833744B
(zh)
|
2018-04-06 |
2024-03-01 |
捷克科學院有機化學與生物化學研究所 |
3'3'-環二核苷酸
|
|
US11142750B2
(en)
|
2018-04-12 |
2021-10-12 |
Precision Biosciences, Inc. |
Optimized engineered meganucleases having specificity for a recognition sequence in the Hepatitis B virus genome
|
|
US20190359645A1
(en)
|
2018-05-03 |
2019-11-28 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3'-cyclic dinucleotides comprising carbocyclic nucleotide
|
|
MX2020012964A
(es)
|
2018-06-01 |
2021-02-16 |
Eisai R&D Man Co Ltd |
Metodos para el tratamiento de cancer de vejiga.
|
|
TW202030199A
(zh)
*
|
2018-07-17 |
2020-08-16 |
美商健生生物科技公司 |
作為ｓｔｉｎｇ促效劑之環狀二核苷酸
|
|
WO2020028097A1
(en)
|
2018-08-01 |
2020-02-06 |
Gilead Sciences, Inc. |
Solid forms of (r)-11-(methoxymethyl)-12-(3-methoxypropoxy)-3,3-dimethyl-8-0x0-2,3,8,13b-tetrahydro-1h-pyrido[2,1-a]pyrrolo[1,2-c] phthalazine-7-c arboxylic acid
|
|
CN112041325B
(zh)
|
2018-08-16 |
2023-10-24 |
卫材R&D管理有限公司 |
化合物的盐及其晶体
|
|
EP3849615A1
(en)
|
2018-09-12 |
2021-07-21 |
Silverback Therapeutics, Inc. |
Compositions for the treatment of disease with immune stimulatory conjugates
|
|
KR20210062668A
(ko)
|
2018-09-21 |
2021-05-31 |
상하이 드 노보 파마테크 컴퍼니 리미티드 |
고리형 디뉴클레오티드 유사체, 이의 약학 조성물 및 용도
|
|
US11110106B2
(en)
|
2018-10-29 |
2021-09-07 |
Venenum Biodesign, LLC |
Sting agonists for treating bladder cancer and solid tumors
|
|
WO2020092127A1
(en)
*
|
2018-10-29 |
2020-05-07 |
Venenum Biodesign, LLC |
Novel sting agonists
|
|
MX2021005047A
(es)
|
2018-10-31 |
2021-09-08 |
Gilead Sciences Inc |
Compuestos de 6-azabenzimidazol sustituidos como inhibidores de hpk1.
|
|
JP7273172B2
(ja)
|
2018-10-31 |
2023-05-12 |
ギリアード サイエンシーズ， インコーポレイテッド |
Ｈｐｋ１阻害活性を有する置換６－アザベンゾイミダゾール化合物
|
|
CN111655712B
(zh)
*
|
2018-12-29 |
2021-02-05 |
上海济煜医药科技有限公司 |
作为肿瘤免疫类的化合物及其应用
|
|
KR20210137517A
(ko)
|
2019-03-07 |
2021-11-17 |
인스티튜트 오브 오가닉 케미스트리 앤드 바이오케미스트리 에이에스 씨알 브이.브이.아이. |
2'3'-사이클릭 다이뉴클레오티드 및 이의 프로드럭
|
|
EP3935066A1
(en)
|
2019-03-07 |
2022-01-12 |
Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. |
3'3'-cyclic dinucleotides and prodrugs thereof
|
|
US11766447B2
(en)
|
2019-03-07 |
2023-09-26 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3′3′-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator
|
|
TWI751517B
(zh)
|
2019-04-17 |
2022-01-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TW202210480A
(zh)
|
2019-04-17 |
2022-03-16 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
CN109929894B
(zh)
*
|
2019-04-17 |
2021-06-01 |
中国农业科学院兰州兽医研究所 |
一种猪源第二信使分子2′3′-cGAMP的制备及活性鉴定方法
|
|
EP3962493A2
(en)
|
2019-05-03 |
2022-03-09 |
Flagship Pioneering Innovations V, Inc. |
Methods of modulating immune activity/level of irf or sting or of treating cancer, comprising the administration of a sting modulator and/or purinergic receptor modulator or postcellular signaling factor
|
|
CA3137119A1
(en)
|
2019-05-09 |
2020-11-12 |
Aligos Therapeutics, Inc. |
Modified cyclic dinucleoside compounds as sting modulators
|
|
WO2020229982A1
(en)
|
2019-05-10 |
2020-11-19 |
Takeda Pharmaceutical Company Limited |
Antibody drug conjugates
|
|
US11453681B2
(en)
|
2019-05-23 |
2022-09-27 |
Gilead Sciences, Inc. |
Substituted eneoxindoles and uses thereof
|
|
EP3990476A1
(en)
|
2019-06-25 |
2022-05-04 |
Gilead Sciences, Inc. |
Flt3l-fc fusion proteins and methods of use
|
|
US20220259254A1
(en)
|
2019-07-05 |
2022-08-18 |
Tambo, Inc. |
Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy
|
|
US20220296619A1
(en)
|
2019-08-19 |
2022-09-22 |
Gilead Sciences, Inc. |
Pharmaceutical formulations of tenofovir alafenamide
|
|
CR20220129A
(es)
|
2019-09-30 |
2022-05-06 |
Gilead Sciences Inc |
Vacunas para vhb y métodos de tratamiento de vhb
|
|
AU2020358726A1
(en)
|
2019-10-01 |
2022-04-07 |
Silverback Therapeutics, Inc. |
Combination therapy with immune stimulatory conjugates
|
|
WO2021113765A1
(en)
|
2019-12-06 |
2021-06-10 |
Precision Biosciences, Inc. |
Optimized engineered meganucleases having specificity for a recognition sequence in the hepatitis b virus genome
|
|
EP4106819A1
(en)
|
2020-02-21 |
2022-12-28 |
Silverback Therapeutics, Inc. |
Nectin-4 antibody conjugates and uses thereof
|
|
CN115605493A
(zh)
|
2020-03-20 |
2023-01-13 |
吉利德科学公司（Us） |
4′-c-取代的-2-卤代-2′-脱氧腺苷核苷的前药及其制备和使用方法
|
|
KR20220167275A
(ko)
|
2020-04-10 |
2022-12-20 |
오노 야꾸힝 고교 가부시키가이샤 |
암 치료 방법
|
|
EP4149440A1
(en)
|
2020-05-11 |
2023-03-22 |
Erytech Pharma |
Red cell extracellular vesicles (rcevs) containing cargoes and methods of use and production thereof
|
|
CN116209678A
(zh)
|
2020-07-01 |
2023-06-02 |
安尔士制药公司 |
抗asgr1抗体缀合物及其用途
|
|
JP2023536663A
(ja)
|
2020-08-07 |
2023-08-28 |
ギリアード サイエンシーズ， インコーポレイテッド |
ホスホンアミドヌクレオチド類似体のプロドラッグ及びその薬学的使用
|
|
EP4192506A1
(en)
|
2020-08-07 |
2023-06-14 |
Tambo, Inc. |
Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy
|
|
JP2023546278A
(ja)
*
|
2020-10-20 |
2023-11-01 |
タイリガンド バイオサイエンス（シャンハイ）リミテッド |
多機能環状ジヌクレオチド及びその使用
|
|
CA3197167A1
(en)
|
2020-11-09 |
2022-05-12 |
He Xu |
Antibody drug conjugates
|
|
AU2022274607A1
(en)
|
2021-05-13 |
2023-11-16 |
Gilead Sciences, Inc. |
COMBINATION OF A TLR8 MODULATING COMPOUND AND ANTI-HBV siRNA THERAPEUTICS
|
|
WO2022245671A1
(en)
|
2021-05-18 |
2022-11-24 |
Gilead Sciences, Inc. |
Methods of using flt3l-fc fusion proteins
|
|
IL309378A
(en)
|
2021-06-23 |
2024-02-01 |
Gilead Sciences Inc |
DIACYLGLYERCOL KINASE MODULATING COMPOUNDS
|
|
WO2022271684A1
(en)
|
2021-06-23 |
2022-12-29 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
|
KR20240023628A
(ko)
|
2021-06-23 |
2024-02-22 |
길리애드 사이언시즈, 인코포레이티드 |
디아실글리세롤 키나제 조절 화합물
|
|
US11926628B2
(en)
|
2021-06-23 |
2024-03-12 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|