JP2020500542A5 - - Google Patents
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- Publication number
- JP2020500542A5 JP2020500542A5 JP2019530803A JP2019530803A JP2020500542A5 JP 2020500542 A5 JP2020500542 A5 JP 2020500542A5 JP 2019530803 A JP2019530803 A JP 2019530803A JP 2019530803 A JP2019530803 A JP 2019530803A JP 2020500542 A5 JP2020500542 A5 JP 2020500542A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- antigen
- binding fragment
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16306655.8 | 2016-12-09 | ||
| EP16306655 | 2016-12-09 | ||
| PCT/EP2017/081911 WO2018104483A1 (en) | 2016-12-09 | 2017-12-07 | Antibodies and polypeptides directed against cd127 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020500542A JP2020500542A (ja) | 2020-01-16 |
| JP2020500542A5 true JP2020500542A5 (https=) | 2021-01-28 |
| JP6986559B2 JP6986559B2 (ja) | 2022-01-05 |
Family
ID=57796143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019530803A Active JP6986559B2 (ja) | 2016-12-09 | 2017-12-07 | Ｃｄ１２７に対して方向付けられた抗体及びポリペプチド |
Country Status (39)
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016156468A1 (en) | 2015-03-31 | 2016-10-06 | Vhsquared Limited | Polypeptides |
| HK1250011A1 (zh) | 2015-03-31 | 2018-11-23 | Sorriso Pharmaceuticals, Inc. | 具有蛋白酶可切割接头的肽构建体 |
| EP3405491A1 (en) | 2016-01-21 | 2018-11-28 | VHsquared Limited | Polypeptides |
| US12016900B2 (en) | 2017-06-04 | 2024-06-25 | Rappaport Family Institute For Research In The Medical Sciences | Method of treating cancer with an immune checkpoint inhibitor in combination with another therapeutic agent |
| US12070489B2 (en) | 2018-12-12 | 2024-08-27 | Rappaport Family Institute For Research In The Medical Sciences | Method of treating cancer with a cancer therapy in combination with another therapeutic agent |
| CA3066053A1 (en) | 2017-06-04 | 2018-12-13 | Rappaport Family Institute For Research In The Medical Sciences | Method of predicting personalized response to cancer treatment with immune checkpoint inhibitors and kits therefor |
| US11008395B2 (en) * | 2019-01-22 | 2021-05-18 | Bristol Myers-Squibb Company | Antibodies against IL-7R alpha subunit and uses thereof |
| KR20220063148A (ko) | 2019-06-21 | 2022-05-17 | 소리소 파마슈티컬스 인크. | 조성물 |
| JP7680377B2 (ja) | 2019-06-21 | 2025-05-20 | ソリッソ ファーマシューティカルズ，インク． | ポリペプチド |
| WO2020254827A1 (en) * | 2019-06-21 | 2020-12-24 | Vhsquared Limited | Polypeptides |
| KR20220110207A (ko) | 2019-11-05 | 2022-08-05 | 메디카인 인코포레이티드 | IL-2RβγC 결합 화합물 |
| CN110894237B (zh) * | 2019-12-05 | 2021-08-03 | 山东省分析测试中心 | 抗cd127的抗体、分泌该抗体的细胞株及其制备方法和应用 |
| IL295304A (en) | 2020-02-03 | 2022-10-01 | Medikine Inc | Il-7 receptor alpha gamma c binding compounds, compositions comprising same and uses thereof |
| US20220389104A1 (en) | 2021-05-28 | 2022-12-08 | Ose Immunotherapeutics | Method for Treating CD127-Positive Cancers by Administering an Anti-CD127 Agent |
| CN113501499A (zh) * | 2021-08-11 | 2021-10-15 | 无锡贝塔医药科技有限公司 | 一种高纯无水溴化氘气体的制备方法及其应用 |
| US11999771B2 (en) | 2022-04-07 | 2024-06-04 | Medikine, Inc. | IL-7Rαγc ligand immunoglobulin fusion proteins |
| CN119301276A (zh) * | 2022-05-30 | 2025-01-10 | Ose免疫疗法 | Il7r调节剂活性的生物标志物 |
| CN115925955B (zh) * | 2022-12-30 | 2025-09-26 | 浙江正熙生物技术有限公司 | 一种抗cd127抗体及其制备方法和应用 |
| EP4455308A1 (en) | 2023-04-24 | 2024-10-30 | Les Laboratoires Servier | Il-7r gene signatures |
| AU2024318231A1 (en) * | 2023-07-31 | 2026-03-12 | Q32 Bio Inc. | Treatment of atopic dermatitis |
| WO2025098341A1 (en) * | 2023-11-10 | 2025-05-15 | Inmagene Biopharmaceuticals (Hangzhou) Co., Ltd. | IL-7Ra TARGETING ANTIBODIES AND USES THEREOF |
| WO2026022216A1 (en) | 2024-07-23 | 2026-01-29 | Ose Immunotherapeutics | Uses of anti-cd127 antibodies in the treatment of inflammatory bowel diseases |
| WO2026062296A1 (en) | 2024-09-23 | 2026-03-26 | Ose Immunotherapeutics | Therapy by antagonizing il-7 or cd127, and il-12, il-23, il-12r or il-23r |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY32038A (es) * | 2008-08-08 | 2010-03-26 | Glaxo Wellcome Mfg Pte Ltd | Inmunoblobulinas anti-cd127 y sus usos |
| MX339083B (es) * | 2010-01-28 | 2016-04-01 | Glaxo Group Ltd | Proteinas de enlace a cd127. |
| AR080291A1 (es) * | 2010-02-24 | 2012-03-28 | Rinat Neuroscience Corp | Anticuerpos antagonistas anti receptor de il-7 y procedimientos |
| EP2583980A1 (en) | 2011-10-19 | 2013-04-24 | Effimune | Antibodies directed against the alpha chain of IL7 receptor - their use for the preparation of drug candidates |
| EP2955196A1 (en) | 2014-06-10 | 2015-12-16 | Effimune | Antibodies directed against CD127 |
| GB201506869D0 (en) * | 2015-04-22 | 2015-06-03 | Ucb Biopharma Sprl | Method |
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2017
- 2017-12-07 DK DK17835592.1T patent/DK3551664T3/da active
- 2017-12-07 AR ARP170103427A patent/AR110326A1/es unknown
- 2017-12-07 EA EA201991005A patent/EA201991005A1/ru unknown
- 2017-12-07 UY UY0001037511A patent/UY37511A/es active IP Right Grant
- 2017-12-07 MX MX2019006577A patent/MX2019006577A/es unknown
- 2017-12-07 UA UAA201905605A patent/UA126386C2/uk unknown
- 2017-12-07 EP EP17835592.1A patent/EP3551664B1/en active Active
- 2017-12-07 AU AU2017373819A patent/AU2017373819B2/en active Active
- 2017-12-07 PH PH1/2019/501285A patent/PH12019501285B1/en unknown
- 2017-12-07 MY MYPI2019003245A patent/MY190770A/en unknown
- 2017-12-07 PL PL17835592T patent/PL3551664T3/pl unknown
- 2017-12-07 CA CA3042582A patent/CA3042582C/en active Active
- 2017-12-07 HU HUE17835592A patent/HUE054206T2/hu unknown
- 2017-12-07 WO PCT/EP2017/081911 patent/WO2018104483A1/en not_active Ceased
- 2017-12-07 SI SI201730717T patent/SI3551664T1/sl unknown
- 2017-12-07 HR HRP20210697TT patent/HRP20210697T1/hr unknown
- 2017-12-07 PE PE2019001201A patent/PE20191152A1/es unknown
- 2017-12-07 MD MDE20191173T patent/MD3551664T2/ro unknown
- 2017-12-07 JP JP2019530803A patent/JP6986559B2/ja active Active
- 2017-12-07 PT PT178355921T patent/PT3551664T/pt unknown
- 2017-12-07 MA MA49727A patent/MA49727B1/fr unknown
- 2017-12-07 RU RU2019115610A patent/RU2769352C2/ru active
- 2017-12-07 TW TW106142933A patent/TWI777996B/zh active
- 2017-12-07 ES ES17835592T patent/ES2867900T3/es active Active
- 2017-12-07 CR CR20190273A patent/CR20190273A/es unknown
- 2017-12-07 LT LTEP17835592.1T patent/LT3551664T/lt unknown
- 2017-12-07 SM SM20210267T patent/SMT202100267T1/it unknown
- 2017-12-07 RS RS20210520A patent/RS61808B1/sr unknown
- 2017-12-07 NZ NZ753213A patent/NZ753213A/en unknown
- 2017-12-07 KR KR1020197019889A patent/KR102306366B1/ko active Active
- 2017-12-07 CN CN201780076086.8A patent/CN110392695B/zh active Active
- 2017-12-07 US US16/467,284 patent/US11098128B2/en active Active
- 2017-12-11 PY PY201701794093A patent/PY1794093A/es unknown
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2019
- 2019-05-02 ZA ZA2019/02743A patent/ZA201902743B/en unknown
- 2019-05-23 IL IL266837A patent/IL266837B/en active IP Right Grant
- 2019-05-30 SA SA519401906A patent/SA519401906B1/ar unknown
- 2019-06-05 CL CL2019001530A patent/CL2019001530A1/es unknown
- 2019-06-05 CO CONC2019/0005909A patent/CO2019005909A2/es unknown
-
2021
- 2021-05-07 CY CY20211100394T patent/CY1124153T1/el unknown
- 2021-06-30 US US17/363,260 patent/US11926671B2/en active Active
-
2024
- 2024-03-09 US US18/600,697 patent/US20240352135A1/en active Pending
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