KR102306366B1 - Cd127에 대해 지시된 항체 및 폴리펩타이드 - Google Patents

Cd127에 대해 지시된 항체 및 폴리펩타이드 Download PDF

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KR102306366B1
KR102306366B1 KR1020197019889A KR20197019889A KR102306366B1 KR 102306366 B1 KR102306366 B1 KR 102306366B1 KR 1020197019889 A KR1020197019889 A KR 1020197019889A KR 20197019889 A KR20197019889 A KR 20197019889A KR 102306366 B1 KR102306366 B1 KR 102306366B1
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니꼴라 뿌와리에
꺄롤린 마리
베르나르 방오브
비르지니 테뻬니에
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오제 이뮈노테라프틱스
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    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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KR1020197019889A 2016-12-09 2017-12-07 Cd127에 대해 지시된 항체 및 폴리펩타이드 Active KR102306366B1 (ko)

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EP16306655.8 2016-12-09
EP16306655 2016-12-09
PCT/EP2017/081911 WO2018104483A1 (en) 2016-12-09 2017-12-07 Antibodies and polypeptides directed against cd127

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WO2016156468A1 (en) 2015-03-31 2016-10-06 Vhsquared Limited Polypeptides
HK1250011A1 (zh) 2015-03-31 2018-11-23 Sorriso Pharmaceuticals, Inc. 具有蛋白酶可切割接头的肽构建体
EP3405491A1 (en) 2016-01-21 2018-11-28 VHsquared Limited Polypeptides
US12016900B2 (en) 2017-06-04 2024-06-25 Rappaport Family Institute For Research In The Medical Sciences Method of treating cancer with an immune checkpoint inhibitor in combination with another therapeutic agent
US12070489B2 (en) 2018-12-12 2024-08-27 Rappaport Family Institute For Research In The Medical Sciences Method of treating cancer with a cancer therapy in combination with another therapeutic agent
CA3066053A1 (en) 2017-06-04 2018-12-13 Rappaport Family Institute For Research In The Medical Sciences Method of predicting personalized response to cancer treatment with immune checkpoint inhibitors and kits therefor
US11008395B2 (en) * 2019-01-22 2021-05-18 Bristol Myers-Squibb Company Antibodies against IL-7R alpha subunit and uses thereof
KR20220063148A (ko) 2019-06-21 2022-05-17 소리소 파마슈티컬스 인크. 조성물
JP7680377B2 (ja) 2019-06-21 2025-05-20 ソリッソ ファーマシューティカルズ,インク. ポリペプチド
WO2020254827A1 (en) * 2019-06-21 2020-12-24 Vhsquared Limited Polypeptides
KR20220110207A (ko) 2019-11-05 2022-08-05 메디카인 인코포레이티드 IL-2RβγC 결합 화합물
CN110894237B (zh) * 2019-12-05 2021-08-03 山东省分析测试中心 抗cd127的抗体、分泌该抗体的细胞株及其制备方法和应用
IL295304A (en) 2020-02-03 2022-10-01 Medikine Inc Il-7 receptor alpha gamma c binding compounds, compositions comprising same and uses thereof
US20220389104A1 (en) 2021-05-28 2022-12-08 Ose Immunotherapeutics Method for Treating CD127-Positive Cancers by Administering an Anti-CD127 Agent
CN113501499A (zh) * 2021-08-11 2021-10-15 无锡贝塔医药科技有限公司 一种高纯无水溴化氘气体的制备方法及其应用
US11999771B2 (en) 2022-04-07 2024-06-04 Medikine, Inc. IL-7Rαγc ligand immunoglobulin fusion proteins
CN119301276A (zh) * 2022-05-30 2025-01-10 Ose免疫疗法 Il7r调节剂活性的生物标志物
CN115925955B (zh) * 2022-12-30 2025-09-26 浙江正熙生物技术有限公司 一种抗cd127抗体及其制备方法和应用
EP4455308A1 (en) 2023-04-24 2024-10-30 Les Laboratoires Servier Il-7r gene signatures
AU2024318231A1 (en) * 2023-07-31 2026-03-12 Q32 Bio Inc. Treatment of atopic dermatitis
WO2025098341A1 (en) * 2023-11-10 2025-05-15 Inmagene Biopharmaceuticals (Hangzhou) Co., Ltd. IL-7Ra TARGETING ANTIBODIES AND USES THEREOF
WO2026022216A1 (en) 2024-07-23 2026-01-29 Ose Immunotherapeutics Uses of anti-cd127 antibodies in the treatment of inflammatory bowel diseases
WO2026062296A1 (en) 2024-09-23 2026-03-26 Ose Immunotherapeutics Therapy by antagonizing il-7 or cd127, and il-12, il-23, il-12r or il-23r

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WO2015189302A1 (en) 2014-06-10 2015-12-17 Effimune Antibodies directed against cd127

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EP2583980A1 (en) 2011-10-19 2013-04-24 Effimune Antibodies directed against the alpha chain of IL7 receptor - their use for the preparation of drug candidates
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WO2011094259A2 (en) 2010-01-28 2011-08-04 Glaxo Group Limited Cd127 binding proteins
WO2011104687A1 (en) 2010-02-24 2011-09-01 Rinat Neuroscience Corporation Antagonist anti-il-7 receptor antibodies and methods
WO2015189302A1 (en) 2014-06-10 2015-12-17 Effimune Antibodies directed against cd127

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CY1124153T1 (el) 2022-05-27
HUE054206T2 (hu) 2021-08-30
KR20190090005A (ko) 2019-07-31
DK3551664T3 (da) 2021-05-03
HRP20210697T1 (hr) 2021-07-23
CN110392695B (zh) 2021-02-02
JP6986559B2 (ja) 2022-01-05
US11926671B2 (en) 2024-03-12
ES2867900T3 (es) 2021-10-21
EA201991005A1 (ru) 2019-12-30
PE20191152A1 (es) 2019-09-05
CN110392695A (zh) 2019-10-29
MA49727A (fr) 2019-10-16
MY190770A (en) 2022-05-12
PT3551664T (pt) 2021-04-21
RU2769352C2 (ru) 2022-03-30
CA3042582C (en) 2023-05-23
MX2019006577A (es) 2019-10-07
PH12019501285B1 (en) 2023-09-08
AR110326A1 (es) 2019-03-20
MA49727B1 (fr) 2021-05-31
US20190375844A1 (en) 2019-12-12
US20210395376A1 (en) 2021-12-23
LT3551664T (lt) 2021-05-25
RS61808B1 (sr) 2021-06-30
JP2020500542A (ja) 2020-01-16
SA519401906B1 (ar) 2022-12-20
PY1794093A (es) 2019-03-01
CA3042582A1 (en) 2018-06-14
TW201833137A (zh) 2018-09-16
CO2019005909A2 (es) 2019-07-31
BR112019010595A2 (pt) 2019-09-17
RU2019115610A (ru) 2021-01-12
UA126386C2 (uk) 2022-09-28
PH12019501285A1 (en) 2019-12-16
TWI777996B (zh) 2022-09-21
NZ753213A (en) 2022-05-27
US20220332834A2 (en) 2022-10-20
EP3551664A1 (en) 2019-10-16
ZA201902743B (en) 2025-11-26
IL266837B (en) 2020-06-30
SMT202100267T1 (it) 2021-07-12
CL2019001530A1 (es) 2019-10-11
UY37511A (es) 2018-06-29
SI3551664T1 (sl) 2021-08-31
IL266837A (en) 2019-07-31
AU2017373819A1 (en) 2019-05-30
WO2018104483A1 (en) 2018-06-14
CR20190273A (es) 2019-10-17
US11098128B2 (en) 2021-08-24
MD3551664T2 (ro) 2021-06-30
AU2017373819B2 (en) 2022-03-31
PL3551664T3 (pl) 2021-08-02
US20240352135A1 (en) 2024-10-24
RU2019115610A3 (https=) 2021-04-05

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