|
US4474893A
(en)
|
1981-07-01 |
1984-10-02 |
The University of Texas System Cancer Center |
Recombinant monoclonal antibodies
|
|
US4714681A
(en)
|
1981-07-01 |
1987-12-22 |
The Board Of Reagents, The University Of Texas System Cancer Center |
Quadroma cells and trioma cells and methods for the production of same
|
|
NZ201918A
(en)
|
1981-09-18 |
1987-04-30 |
Genentech Inc |
N-terminal methionyl analogues of bovine growth hormone
|
|
US4683195A
(en)
|
1986-01-30 |
1987-07-28 |
Cetus Corporation |
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US4873192A
(en)
|
1987-02-17 |
1989-10-10 |
The United States Of America As Represented By The Department Of Health And Human Services |
Process for site specific mutagenesis without phenotypic selection
|
|
US5892019A
(en)
|
1987-07-15 |
1999-04-06 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Production of a single-gene-encoded immunoglobulin
|
|
AU631802B2
(en)
|
1988-06-14 |
1992-12-10 |
Cetus Oncology Corporation |
Coupling agents and sterically hindered disulfide linked conjugates prepared therefrom
|
|
US4925648A
(en)
|
1988-07-29 |
1990-05-15 |
Immunomedics, Inc. |
Detection and treatment of infectious and inflammatory lesions
|
|
US5601819A
(en)
|
1988-08-11 |
1997-02-11 |
The General Hospital Corporation |
Bispecific antibodies for selective immune regulation and for selective immune cell binding
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5116964A
(en)
|
1989-02-23 |
1992-05-26 |
Genentech, Inc. |
Hybrid immunoglobulins
|
|
US5225538A
(en)
|
1989-02-23 |
1993-07-06 |
Genentech, Inc. |
Lymphocyte homing receptor/immunoglobulin fusion proteins
|
|
IE63847B1
(en)
|
1989-05-05 |
1995-06-14 |
Res Dev Foundation |
A novel antibody delivery system for biological response modifiers
|
|
ES2096590T3
(es)
|
1989-06-29 |
1997-03-16 |
Medarex Inc |
Reactivos biespecificos para la terapia del sida.
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
DE69120146T2
(de)
|
1990-01-12 |
1996-12-12 |
Cell Genesys Inc |
Erzeugung xenogener antikörper
|
|
US5314995A
(en)
|
1990-01-22 |
1994-05-24 |
Oncogen |
Therapeutic interleukin-2-antibody based fusion proteins
|
|
WO1991014438A1
(en)
|
1990-03-20 |
1991-10-03 |
The Trustees Of Columbia University In The City Of New York |
Chimeric antibodies with receptor binding ligands in place of their constant region
|
|
DK0553244T4
(da)
|
1990-10-05 |
2005-08-01 |
Celldex Therapeutics Inc |
Målrettet immunostimulering med bispecifikke reagenser
|
|
WO1992008802A1
(en)
|
1990-10-29 |
1992-05-29 |
Cetus Oncology Corporation |
Bispecific antibodies, method of production, and uses thereof
|
|
DE69133036T2
(de)
|
1990-11-09 |
2003-02-06 |
Stephen D. Gillies |
Cytokine immunokonjugate
|
|
CA2108451A1
(en)
|
1991-04-26 |
1992-10-27 |
Beverley J. Randle |
Novel antibodies, and methods for their use
|
|
FR2686087A1
(fr)
|
1992-01-13 |
1993-07-16 |
Inst Nat Sante Rech Med |
Nouvel antigene lymphocytaire, anticorps correspondant et leurs applications.
|
|
PT627940E
(pt)
|
1992-03-05 |
2003-07-31 |
Univ Texas |
Utilizacao de imunoconjugados para o diagnostico e/ou terapia de tumores vascularizados
|
|
US6692920B1
(en)
|
1994-12-07 |
2004-02-17 |
Incyte Corporation |
Antibodies to a chemokine expressed in inflamed adenoid
|
|
US5633149A
(en)
|
1994-12-07 |
1997-05-27 |
Incyte Pharmaceuticals, Inc. |
Polynucleotide encoding novel chemokine expressed in inflamed adenoid
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
CN1190991A
(zh)
|
1995-06-05 |
1998-08-19 |
人类基因组科学公司 |
人类趋化因子β-11和人类趋化因子α-1
|
|
AU4243097A
(en)
|
1996-09-10 |
1998-04-02 |
Schering Corporation |
Mammalian chemokines, related reagents
|
|
US6852508B1
(en)
|
1997-02-28 |
2005-02-08 |
Genetics Institute, Llc |
Chemokine with amino-terminal modifications
|
|
US20030207346A1
(en)
|
1997-05-02 |
2003-11-06 |
William R. Arathoon |
Method for making multispecific antibodies having heteromultimeric and common components
|
|
US6110695A
(en)
|
1997-12-02 |
2000-08-29 |
The Regents Of The University Of California |
Modulating the interaction of the chemokine, B Lymphocyte Hemoattractant, and its Receptor, BLR1
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
US6897044B1
(en)
|
1999-01-28 |
2005-05-24 |
Biogen Idec, Inc. |
Production of tetravalent antibodies
|
|
US6723538B2
(en)
|
1999-03-11 |
2004-04-20 |
Micromet Ag |
Bispecific antibody and chemokine receptor constructs
|
|
US6849425B1
(en)
|
1999-10-14 |
2005-02-01 |
Ixsys, Inc. |
Methods of optimizing antibody variable region binding affinity
|
|
AU2001250412A1
(en)
|
2000-03-31 |
2001-10-08 |
Ipf Pharmaceuticals Gmbh |
Diagnostic and medicament for analysing the cell surface proteome of tumour and inflammatory cells and for treating tumorous and inflammatory diseases, preferably using specific chemokine receptor analysis and the chemokine receptor-ligand interaction
|
|
GB2361003A
(en)
|
2000-04-07 |
2001-10-10 |
Astrazeneca Ab |
Novel compounds
|
|
US7052676B2
(en)
|
2000-09-26 |
2006-05-30 |
The Regents Of The University Of Michigan |
Methods for inhibition of HIV replication using a small molecule inhibitor
|
|
MXPA03004913A
(es)
|
2000-12-01 |
2003-09-05 |
Schering Corp |
Usos de genes de mamifero y reactivos relacionados.
|
|
WO2002096948A2
(en)
|
2001-01-29 |
2002-12-05 |
Idec Pharmaceuticals Corporation |
Engineered tetravalent antibodies and methods of use
|
|
US6818406B2
(en)
|
2001-03-23 |
2004-11-16 |
Mayo Foundation For Medical Education And Research |
Rheumatoid arthritis markers
|
|
US7413866B2
(en)
|
2001-11-30 |
2008-08-19 |
Chemocentryx, Inc. |
Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
|
|
US7442512B2
(en)
|
2001-11-30 |
2008-10-28 |
Chemocentryx, Inc. |
Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
|
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
|
ATE483472T1
(de)
|
2002-05-30 |
2010-10-15 |
Macrogenics Inc |
Cd16a bindungsproteine und verwendung zur behandlung von immunkrankheiten
|
|
EP2322200A3
(en)
|
2002-10-29 |
2011-07-27 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
WO2004045525A2
(en)
|
2002-11-15 |
2004-06-03 |
Morehouse School Of Medicine |
Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation.
|
|
WO2004045526A2
(en)
|
2002-11-15 |
2004-06-03 |
Morehouse School Of Medicine |
Anti-chemokine and associated receptors antibodies for inhibition of growth of neoplasms
|
|
JP2011516026A
(ja)
|
2002-11-26 |
2011-05-26 |
ジェネンテック・インコーポレーテッド |
免疫関連疾患の治療のための組成物と方法
|
|
EA200501524A1
(ru)
|
2003-03-28 |
2006-06-30 |
Сентокор, Инк. |
Антитела против амилоида, композиции, способы и применения
|
|
AU2005243730B2
(en)
|
2004-04-12 |
2010-05-27 |
Genvec, Inc. |
Method of using adenoviral vectors to induce an immune response
|
|
CA2501422C
(en)
|
2004-04-29 |
2014-08-12 |
University Of Rochester |
Lymphoid chemokines in the diagnosis, monitoring and treatment of autoimmune disease
|
|
SI1674111T1
(sl)
|
2004-07-09 |
2011-02-28 |
Chugai Pharmaceutical Co Ltd |
Protitelo proti glipikanu 3
|
|
CN101120021A
(zh)
|
2004-12-31 |
2008-02-06 |
基因技术公司 |
结合br3的多肽及其用途
|
|
ES2971647T3
(es)
|
2005-04-15 |
2024-06-06 |
Macrogenics Inc |
Diacuerpos covalentes y usos de los mismos
|
|
US20090041783A1
(en)
|
2005-04-28 |
2009-02-12 |
Mochida Pharmaceutical Co., Ltd. |
Anti-platelet membrane glycoprotein vi monoclonal antibody
|
|
WO2007064911A1
(en)
|
2005-12-02 |
2007-06-07 |
Biogen Idec Inc. |
Anti-mouse cd20 antibodies and uses thereof
|
|
GB0607774D0
(en)
*
|
2006-04-20 |
2006-05-31 |
Renovo Group Plc |
Medicaments
|
|
WO2007124414A2
(en)
|
2006-04-21 |
2007-11-01 |
Centocor, Inc. |
Cxcl13 antagonists and their use for the treatment of inflammatory diseases
|
|
US20080227704A1
(en)
|
2006-12-21 |
2008-09-18 |
Kamens Joanne S |
CXCL13 binding proteins
|
|
US20080199481A1
(en)
*
|
2007-02-21 |
2008-08-21 |
Astrazeneca Ab |
Compounds
|
|
MX2009010633A
(es)
|
2007-03-30 |
2009-11-26 |
Centocor Ortho Biotech Inc |
Antagonistas de la quimiocina interleucina-13 y su uso para el tratamiento de enfermedades inflamatorias.
|
|
WO2010053547A2
(en)
*
|
2008-11-04 |
2010-05-14 |
Anchor Therapeutics, Inc. |
Cxcr5 receptor compounds
|
|
SG188285A1
(en)
*
|
2010-09-02 |
2013-04-30 |
Vaccinex Inc |
Anti-cxcl13 antibodies and methods of using the same
|
|
WO2013102123A2
(en)
|
2011-12-28 |
2013-07-04 |
Novelmed Therapeutics, Inc. |
Aglycosylated human antibody and fusion protein and uses thereof
|
|
CN105408355A
(zh)
|
2013-01-31 |
2016-03-16 |
瓦克纳斯有限公司 |
用于提高免疫球蛋白a水平的方法
|
|
AU2013205589A1
(en)
|
2013-03-08 |
2014-09-25 |
Vaccinex, Inc. |
Anti-CXCL13 antibodies and associated epitope sequences
|