KR102090969B1 - Ｂ 세포-매개 염증 질환의 치료 방법 - Google Patents

Ｂ 세포-매개 염증 질환의 치료 방법 Download PDF

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KR102090969B1
KR102090969B1 KR1020147027747A KR20147027747A KR102090969B1 KR 102090969 B1 KR102090969 B1 KR 102090969B1 KR 1020147027747 A KR1020147027747 A KR 1020147027747A KR 20147027747 A KR20147027747 A KR 20147027747A KR 102090969 B1 KR102090969 B1 KR 102090969B1
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seq
antibody
amino acid
leu
cxcl13
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KR20140138830A (ko
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어네스트 에스. 스미스
모리스 저더러
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백시넥스 인코포레이티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020147027747A 2012-03-02 2013-03-01 Ｂ 세포-매개 염증 질환의 치료 방법 Active KR102090969B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261606049P 2012-03-02 2012-03-02
US61/606,049 2012-03-02
PCT/US2013/028602 WO2013130959A1 (en) 2012-03-02 2013-03-01 Methods for the treatment of b cell-mediated inflammatory diseases

Publications (2)

Publication Number Publication Date
KR20140138830A KR20140138830A (ko) 2014-12-04
KR102090969B1 true KR102090969B1 (ko) 2020-03-19

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KR1020147027747A Active KR102090969B1 (ko) 2012-03-02 2013-03-01 Ｂ 세포-매개 염증 질환의 치료 방법

Country Status (10)

Country Link
US (1) US9890213B2 (https=)
EP (1) EP2820045B1 (https=)
JP (1) JP6193275B2 (https=)
KR (1) KR102090969B1 (https=)
CN (1) CN104520323B (https=)
AU (1) AU2013225812B2 (https=)
CA (1) CA2865928C (https=)
IN (1) IN2014DN08199A (https=)
NZ (1) NZ629828A (https=)
WO (1) WO2013130959A1 (https=)

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AU2012322721B2 (en) 2011-10-11 2016-05-05 Vaccinex, Inc. Use of semaphorin-4D binding molecules for modulation of blood brain barrier permeability
US9708601B2 (en) 2012-04-26 2017-07-18 Vaccinex, Inc. Fusion proteins to facilitate selection of cells infected with specific immunoglobulin gene recombinant vaccinia virus
CN105408355A (zh) * 2013-01-31 2016-03-16 瓦克纳斯有限公司 用于提高免疫球蛋白a水平的方法
BR112015032690B1 (pt) 2013-06-25 2020-03-10 Vaccinex, Inc. Uso de moléculas inibidoras de semaforina-4d em combinação com uma terapia imunomoduladora para inibir o crescimento tumoral e metástase
US10577427B2 (en) 2016-04-22 2020-03-03 Vaccinex, Inc. Integral membrane protein display on poxvirus extracellular enveloped virions
BR112019001944A2 (pt) 2016-08-02 2019-05-07 Vaccinex, Inc. métodos aperfeiçoados para produção de bibiliotecas de polinucleotídeo em células eucarióticas/vírus de vaccínia
SG11201901789WA (en) * 2016-09-19 2019-03-28 I Mab Anti-gm-csf antibodies and uses thereof
US11554131B2 (en) * 2018-05-31 2023-01-17 Glycom A/S Mixture of HMOs for treating autoimmune diseases
SG11202010499UA (en) * 2018-09-18 2020-11-27 I Mab Biopharma Us Ltd Anti-cxcl13 antibodies for treating autoimmune diseases and cancer

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WO2012031099A2 (en) 2010-09-02 2012-03-08 Vaccinex, Inc. Anti-cxcl13 antibodies and methods of using the same

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Also Published As

Publication number Publication date
CN104520323A (zh) 2015-04-15
JP2015509960A (ja) 2015-04-02
NZ629828A (en) 2017-05-26
CA2865928A1 (en) 2013-09-06
JP6193275B2 (ja) 2017-09-06
CA2865928C (en) 2021-02-16
AU2013225812A1 (en) 2014-09-25
WO2013130959A1 (en) 2013-09-06
US9890213B2 (en) 2018-02-13
KR20140138830A (ko) 2014-12-04
EP2820045B1 (en) 2018-08-22
EP2820045A1 (en) 2015-01-07
IN2014DN08199A (https=) 2015-05-01
AU2013225812B2 (en) 2017-11-30
CN104520323B (zh) 2018-05-04
US20150125467A1 (en) 2015-05-07

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