JP2020146575A5 - - Google Patents
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- JP2020146575A5 JP2020146575A5 JP2020105536A JP2020105536A JP2020146575A5 JP 2020146575 A5 JP2020146575 A5 JP 2020146575A5 JP 2020105536 A JP2020105536 A JP 2020105536A JP 2020105536 A JP2020105536 A JP 2020105536A JP 2020146575 A5 JP2020146575 A5 JP 2020146575A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- culturing
- human rpe
- pigmented
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- 210000004027 cell Anatomy 0.000 claims 34
- 101000670189 Homo sapiens Ribulose-phosphate 3-epimerase Proteins 0.000 claims 14
- 238000000034 method Methods 0.000 claims 14
- 238000012258 culturing Methods 0.000 claims 10
- 210000002242 embryoid body Anatomy 0.000 claims 5
- 239000002356 single layer Substances 0.000 claims 5
- 101001078886 Homo sapiens Retinaldehyde-binding protein 1 Proteins 0.000 claims 3
- 101000729271 Homo sapiens Retinoid isomerohydrolase Proteins 0.000 claims 3
- 102100035846 Pigment epithelium-derived factor Human genes 0.000 claims 3
- 102100028001 Retinaldehyde-binding protein 1 Human genes 0.000 claims 3
- 102100031176 Retinoid isomerohydrolase Human genes 0.000 claims 3
- 238000002347 injection Methods 0.000 claims 3
- 239000007924 injection Substances 0.000 claims 3
- 108090000102 pigment epithelium-derived factor Proteins 0.000 claims 3
- 108010058237 plasma protein fraction Proteins 0.000 claims 3
- 229940002993 plasmanate Drugs 0.000 claims 3
- 210000001316 polygonal cell Anatomy 0.000 claims 3
- 238000002054 transplantation Methods 0.000 claims 3
- 210000001339 epidermal cell Anatomy 0.000 claims 2
- 210000002919 epithelial cell Anatomy 0.000 claims 2
- 239000010410 layer Substances 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- -1 vestrophin Proteins 0.000 claims 2
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims 1
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims 1
- 108010067306 Fibronectins Proteins 0.000 claims 1
- 102000016359 Fibronectins Human genes 0.000 claims 1
- 108010010803 Gelatin Proteins 0.000 claims 1
- 102000007547 Laminin Human genes 0.000 claims 1
- 108010085895 Laminin Proteins 0.000 claims 1
- 201000007737 Retinal degeneration Diseases 0.000 claims 1
- 208000027073 Stargardt disease Diseases 0.000 claims 1
- 206010064930 age-related macular degeneration Diseases 0.000 claims 1
- 239000001058 brown pigment Substances 0.000 claims 1
- 239000006285 cell suspension Substances 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- 210000000805 cytoplasm Anatomy 0.000 claims 1
- 208000001309 degenerative myopia Diseases 0.000 claims 1
- 230000004340 degenerative myopia Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 210000002744 extracellular matrix Anatomy 0.000 claims 1
- 229920000159 gelatin Polymers 0.000 claims 1
- 239000008273 gelatin Substances 0.000 claims 1
- 235000019322 gelatine Nutrition 0.000 claims 1
- 235000011852 gelatine desserts Nutrition 0.000 claims 1
- 208000002780 macular degeneration Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000004258 retinal degeneration Effects 0.000 claims 1
- 239000000790 retinal pigment Substances 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022124147A JP2022153630A (ja) | 2004-01-23 | 2022-08-03 | 網膜変性疾患治療のための改良された様式 |
| JP2024007584A JP2024038460A (ja) | 2004-01-23 | 2024-01-22 | 網膜変性疾患治療のための改良された様式 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53896404P | 2004-01-23 | 2004-01-23 | |
| US60/538,964 | 2004-01-23 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019170249A Division JP2019217356A (ja) | 2004-01-23 | 2019-09-19 | 網膜変性疾患治療のための改良された様式 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022124147A Division JP2022153630A (ja) | 2004-01-23 | 2022-08-03 | 網膜変性疾患治療のための改良された様式 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020146575A JP2020146575A (ja) | 2020-09-17 |
| JP2020146575A5 true JP2020146575A5 (enExample) | 2021-03-25 |
Family
ID=34807248
Family Applications (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551392A Pending JP2007522131A (ja) | 2004-01-23 | 2005-01-24 | 網膜変性疾患治療のための改良された様式 |
| JP2012040491A Pending JP2012148085A (ja) | 2004-01-23 | 2012-02-27 | 網膜変性疾患治療のための改良された様式 |
| JP2014016135A Ceased JP2014079650A (ja) | 2004-01-23 | 2014-01-30 | 網膜変性疾患治療のための改良された様式 |
| JP2015025500A Ceased JP2015096556A (ja) | 2004-01-23 | 2015-02-12 | 網膜変性疾患治療のための改良された様式 |
| JP2016152133A Withdrawn JP2016195862A (ja) | 2004-01-23 | 2016-08-02 | 網膜変性疾患治療のための改良された様式 |
| JP2017254812A Ceased JP2018086274A (ja) | 2004-01-23 | 2017-12-28 | 網膜変性疾患治療のための改良された様式 |
| JP2019170249A Pending JP2019217356A (ja) | 2004-01-23 | 2019-09-19 | 網膜変性疾患治療のための改良された様式 |
| JP2020105536A Ceased JP2020146575A (ja) | 2004-01-23 | 2020-06-18 | 網膜変性疾患治療のための改良された様式 |
| JP2022124147A Pending JP2022153630A (ja) | 2004-01-23 | 2022-08-03 | 網膜変性疾患治療のための改良された様式 |
| JP2024007584A Pending JP2024038460A (ja) | 2004-01-23 | 2024-01-22 | 網膜変性疾患治療のための改良された様式 |
Family Applications Before (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551392A Pending JP2007522131A (ja) | 2004-01-23 | 2005-01-24 | 網膜変性疾患治療のための改良された様式 |
| JP2012040491A Pending JP2012148085A (ja) | 2004-01-23 | 2012-02-27 | 網膜変性疾患治療のための改良された様式 |
| JP2014016135A Ceased JP2014079650A (ja) | 2004-01-23 | 2014-01-30 | 網膜変性疾患治療のための改良された様式 |
| JP2015025500A Ceased JP2015096556A (ja) | 2004-01-23 | 2015-02-12 | 網膜変性疾患治療のための改良された様式 |
| JP2016152133A Withdrawn JP2016195862A (ja) | 2004-01-23 | 2016-08-02 | 網膜変性疾患治療のための改良された様式 |
| JP2017254812A Ceased JP2018086274A (ja) | 2004-01-23 | 2017-12-28 | 網膜変性疾患治療のための改良された様式 |
| JP2019170249A Pending JP2019217356A (ja) | 2004-01-23 | 2019-09-19 | 網膜変性疾患治療のための改良された様式 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022124147A Pending JP2022153630A (ja) | 2004-01-23 | 2022-08-03 | 網膜変性疾患治療のための改良された様式 |
| JP2024007584A Pending JP2024038460A (ja) | 2004-01-23 | 2024-01-22 | 網膜変性疾患治療のための改良された様式 |
Country Status (15)
| Country | Link |
|---|---|
| US (6) | US7736896B2 (enExample) |
| EP (8) | EP2438814A3 (enExample) |
| JP (10) | JP2007522131A (enExample) |
| KR (3) | KR101398356B1 (enExample) |
| CN (3) | CN1968608B (enExample) |
| AU (6) | AU2005207042B2 (enExample) |
| BR (1) | BRPI0507074A (enExample) |
| CA (2) | CA2937099A1 (enExample) |
| ES (1) | ES2721174T3 (enExample) |
| HK (2) | HK1216068A1 (enExample) |
| IL (3) | IL177015B (enExample) |
| MX (4) | MX375065B (enExample) |
| NZ (1) | NZ548929A (enExample) |
| SG (4) | SG188122A1 (enExample) |
| WO (1) | WO2005070011A2 (enExample) |
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| CN1966080B (zh) * | 2005-11-17 | 2011-06-08 | 李凌松 | 一种治疗老年痴呆症、帕金森病的神经干细胞注射液 |
| US7541186B2 (en) * | 2006-02-22 | 2009-06-02 | University Of Washington | Method of generating human retinal progenitors from embryonic stem cells |
| EP2029724A4 (en) | 2006-05-03 | 2010-03-24 | Advanced Cell Tech Inc | DERIVATION FROM EMBRYONAL STEM CELLS AND EMBRYO-DERIVED CELLS |
| EP2128244A4 (en) * | 2007-01-18 | 2012-05-09 | Riken | PROCESS FOR INDUCTION / DIFFERENTIATION TO A PHOTOREZEPTORZELLE |
| KR20100014504A (ko) | 2007-02-23 | 2010-02-10 | 어드밴스드 셀 테크놀로지, 인코포레이티드 | 분화된 세포를 리프로그래밍하고, 리프로그래밍된 세포로부터 동물 및 배아 줄기세포를 생성시키기 위한 고도로 효율적인 방법 |
| CA2684460C (en) * | 2007-04-18 | 2017-01-03 | Hadasit Medical Research Services & Development Limited | Stem cell-derived retinal pigment epithelial cells |
| EP2607477B1 (en) | 2007-05-03 | 2020-09-23 | The Brigham and Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| US8574567B2 (en) | 2007-05-03 | 2013-11-05 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| US20090028831A1 (en) * | 2007-07-23 | 2009-01-29 | University Of Kentucky Research Foundation | Stem cell regulator, compositions and methods of use |
| EP2209888B1 (en) * | 2007-10-12 | 2019-12-04 | Astellas Institute for Regenerative Medicine | Improved methods of producing rpe cells and compositions of rpe cells |
| AU2015201435B2 (en) * | 2007-10-12 | 2017-02-02 | Astellas Institute For Regenerative Medicine | Improved methods of producing RPE cells and compositions of RPE cells |
| EP2279247B1 (en) * | 2008-04-22 | 2019-01-02 | Regenerative Research Foundation | Retinal pigment epithelial stem cells |
| EP3553170B1 (en) | 2009-08-24 | 2024-02-14 | Wisconsin Alumni Research Foundation | Substantially pure human retinal progenitor, forebrain progenitor, and retinal pigment epithelium cell cultures and methods of making the same |
| IL281453B (en) * | 2009-11-17 | 2022-07-01 | Astellas Inst For Regenerative Medicine | Methods for preparing human rpe cells and pharmaceutical preparations of human rpe cells |
| AU2011279250B2 (en) | 2010-07-12 | 2014-12-04 | California Institute Of Technology | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
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| JP2012231786A (ja) * | 2011-04-18 | 2012-11-29 | Kyushu Univ | 標的遺伝子の発現変化による食品機能成分及び医薬品感受性評価方法 |
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| RU2730937C1 (ru) * | 2019-11-01 | 2020-08-26 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр глазных болезней имени Гельмгольца" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ГБ им. Гельмгольца" Миндрава России) | Способ трансплантации клеток ретинального пигментного эпителия (РПЭ), дифференцированных из индуцированных плюрипотентных стволовых клеток человека, при атрофии ретинального пигментного эпителия |
| WO2022191216A1 (ja) | 2021-03-09 | 2022-09-15 | 国立研究開発法人理化学研究所 | 低免疫原性網膜色素上皮細胞の製造方法 |
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