JP2020054808A - 汎用線形バットレス保持/解放アセンブリおよび方法 - Google Patents
汎用線形バットレス保持/解放アセンブリおよび方法 Download PDFInfo
- Publication number
- JP2020054808A JP2020054808A JP2019169322A JP2019169322A JP2020054808A JP 2020054808 A JP2020054808 A JP 2020054808A JP 2019169322 A JP2019169322 A JP 2019169322A JP 2019169322 A JP2019169322 A JP 2019169322A JP 2020054808 A JP2020054808 A JP 2020054808A
- Authority
- JP
- Japan
- Prior art keywords
- sleeve
- buttress
- buttress material
- jaw member
- surgical stapling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000014759 maintenance of location Effects 0.000 title claims abstract description 43
- 238000000034 method Methods 0.000 title abstract description 20
- 238000000429 assembly Methods 0.000 title abstract description 4
- 230000000712 assembly Effects 0.000 title abstract description 4
- 239000000463 material Substances 0.000 claims abstract description 210
- 230000001154 acute effect Effects 0.000 claims description 5
- 239000012858 resilient material Substances 0.000 claims description 3
- 230000004913 activation Effects 0.000 claims description 2
- 238000003825 pressing Methods 0.000 claims description 2
- 210000001519 tissue Anatomy 0.000 description 40
- 239000012867 bioactive agent Substances 0.000 description 12
- -1 polypropylene Polymers 0.000 description 11
- 239000000835 fiber Substances 0.000 description 9
- 239000011148 porous material Substances 0.000 description 8
- 230000003014 reinforcing effect Effects 0.000 description 8
- 239000003795 chemical substances by application Substances 0.000 description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 239000001961 anticonvulsive agent Substances 0.000 description 3
- 239000000739 antihistaminic agent Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 239000006260 foam Substances 0.000 description 3
- 102000004196 processed proteins & peptides Human genes 0.000 description 3
- 108090000765 processed proteins & peptides Proteins 0.000 description 3
- 235000018102 proteins Nutrition 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 230000002787 reinforcement Effects 0.000 description 3
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 2
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 2
- BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical compound COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 description 2
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 description 2
- 229940035676 analgesics Drugs 0.000 description 2
- 239000000730 antalgic agent Substances 0.000 description 2
- 230000002921 anti-spasmodic effect Effects 0.000 description 2
- 229940125681 anticonvulsant agent Drugs 0.000 description 2
- 239000000427 antigen Substances 0.000 description 2
- 108091007433 antigens Proteins 0.000 description 2
- 102000036639 antigens Human genes 0.000 description 2
- 229940125715 antihistaminic agent Drugs 0.000 description 2
- 239000002246 antineoplastic agent Substances 0.000 description 2
- 229940124575 antispasmodic agent Drugs 0.000 description 2
- 229920001222 biopolymer Polymers 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000003114 blood coagulation factor Substances 0.000 description 2
- 239000002327 cardiovascular agent Substances 0.000 description 2
- 229940125692 cardiovascular agent Drugs 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 229960003260 chlorhexidine Drugs 0.000 description 2
- MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 description 2
- OROGSEYTTFOCAN-DNJOTXNNSA-N codeine Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 description 2
- 238000005520 cutting process Methods 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 238000004108 freeze drying Methods 0.000 description 2
- 239000003102 growth factor Substances 0.000 description 2
- 230000003054 hormonal effect Effects 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 description 2
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 description 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 229920001281 polyalkylene Polymers 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- NDVLTYZPCACLMA-UHFFFAOYSA-N silver oxide Chemical compound [O-2].[Ag+].[Ag+] NDVLTYZPCACLMA-UHFFFAOYSA-N 0.000 description 2
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 description 2
- 150000003431 steroids Chemical class 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 229920002994 synthetic fiber Polymers 0.000 description 2
- 229960005486 vaccine Drugs 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 1
- ICGQLNMKJVHCIR-UHFFFAOYSA-N 1,3,2-dioxazetidin-4-one Chemical compound O=C1ONO1 ICGQLNMKJVHCIR-UHFFFAOYSA-N 0.000 description 1
- ZXSQEZNORDWBGZ-UHFFFAOYSA-N 1,3-dihydropyrrolo[2,3-b]pyridin-2-one Chemical compound C1=CN=C2NC(=O)CC2=C1 ZXSQEZNORDWBGZ-UHFFFAOYSA-N 0.000 description 1
- JKFYKCYQEWQPTM-UHFFFAOYSA-N 2-azaniumyl-2-(4-fluorophenyl)acetate Chemical compound OC(=O)C(N)C1=CC=C(F)C=C1 JKFYKCYQEWQPTM-UHFFFAOYSA-N 0.000 description 1
- 108010088751 Albumins Proteins 0.000 description 1
- 102000009027 Albumins Human genes 0.000 description 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- 108010001478 Bacitracin Proteins 0.000 description 1
- 102000015081 Blood Coagulation Factors Human genes 0.000 description 1
- 108010039209 Blood Coagulation Factors Proteins 0.000 description 1
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 101000798100 Bos taurus Lactotransferrin Proteins 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 102000053642 Catalytic RNA Human genes 0.000 description 1
- 108090000994 Catalytic RNA Proteins 0.000 description 1
- 229930186147 Cephalosporin Natural products 0.000 description 1
- 102000019034 Chemokines Human genes 0.000 description 1
- 108010012236 Chemokines Proteins 0.000 description 1
- 229920001661 Chitosan Polymers 0.000 description 1
- WJLVQTJZDCGNJN-UHFFFAOYSA-N Chlorhexidine hydrochloride Chemical compound Cl.Cl.C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 WJLVQTJZDCGNJN-UHFFFAOYSA-N 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 108010071942 Colony-Stimulating Factors Proteins 0.000 description 1
- 102000007644 Colony-Stimulating Factors Human genes 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 108020004414 DNA Proteins 0.000 description 1
- XIQVNETUBQGFHX-UHFFFAOYSA-N Ditropan Chemical compound C=1C=CC=CC=1C(O)(C(=O)OCC#CCN(CC)CC)C1CCCCC1 XIQVNETUBQGFHX-UHFFFAOYSA-N 0.000 description 1
- 102000016942 Elastin Human genes 0.000 description 1
- 108010014258 Elastin Proteins 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 102000003951 Erythropoietin Human genes 0.000 description 1
- 108090000394 Erythropoietin Proteins 0.000 description 1
- 102000009123 Fibrin Human genes 0.000 description 1
- 108010073385 Fibrin Proteins 0.000 description 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
- 108010049003 Fibrinogen Proteins 0.000 description 1
- 102000008946 Fibrinogen Human genes 0.000 description 1
- IECPWNUMDGFDKC-UHFFFAOYSA-N Fusicsaeure Natural products C12C(O)CC3C(=C(CCC=C(C)C)C(O)=O)C(OC(C)=O)CC3(C)C1(C)CCC1C2(C)CCC(O)C1C IECPWNUMDGFDKC-UHFFFAOYSA-N 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 description 1
- 229930182566 Gentamicin Natural products 0.000 description 1
- 102000006771 Gonadotropins Human genes 0.000 description 1
- 108010086677 Gonadotropins Proteins 0.000 description 1
- 102100039619 Granulocyte colony-stimulating factor Human genes 0.000 description 1
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 description 1
- 102100039620 Granulocyte-macrophage colony-stimulating factor Human genes 0.000 description 1
- 101000746367 Homo sapiens Granulocyte colony-stimulating factor Proteins 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 1
- 108060003951 Immunoglobulin Proteins 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 description 1
- 102000014150 Interferons Human genes 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- 108010002350 Interleukin-2 Proteins 0.000 description 1
- 108010002386 Interleukin-3 Proteins 0.000 description 1
- 108090000978 Interleukin-4 Proteins 0.000 description 1
- 108090001005 Interleukin-6 Proteins 0.000 description 1
- 108010063738 Interleukins Proteins 0.000 description 1
- 102000015696 Interleukins Human genes 0.000 description 1
- 108010076876 Keratins Proteins 0.000 description 1
- 102000011782 Keratins Human genes 0.000 description 1
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 description 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 description 1
- 101800004361 Lactoferricin-B Proteins 0.000 description 1
- 108010074338 Lymphokines Proteins 0.000 description 1
- 102000008072 Lymphokines Human genes 0.000 description 1
- 102100028123 Macrophage colony-stimulating factor 1 Human genes 0.000 description 1
- 101710127797 Macrophage colony-stimulating factor 1 Proteins 0.000 description 1
- XADCESSVHJOZHK-UHFFFAOYSA-N Meperidine Chemical compound C=1C=CC=CC=1C1(C(=O)OCC)CCN(C)CC1 XADCESSVHJOZHK-UHFFFAOYSA-N 0.000 description 1
- BYBLEWFAAKGYCD-UHFFFAOYSA-N Miconazole Chemical compound ClC1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 BYBLEWFAAKGYCD-UHFFFAOYSA-N 0.000 description 1
- 102000013967 Monokines Human genes 0.000 description 1
- 108010050619 Monokines Proteins 0.000 description 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 1
- 229930193140 Neomycin Natural products 0.000 description 1
- 108010025020 Nerve Growth Factor Proteins 0.000 description 1
- 102000015336 Nerve Growth Factor Human genes 0.000 description 1
- SNIOPGDIGTZGOP-UHFFFAOYSA-N Nitroglycerin Chemical compound [O-][N+](=O)OCC(O[N+]([O-])=O)CO[N+]([O-])=O SNIOPGDIGTZGOP-UHFFFAOYSA-N 0.000 description 1
- 239000000006 Nitroglycerin Substances 0.000 description 1
- 101710163270 Nuclease Proteins 0.000 description 1
- 108091034117 Oligonucleotide Proteins 0.000 description 1
- 229940123257 Opioid receptor antagonist Drugs 0.000 description 1
- 229930182555 Penicillin Natural products 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 229920000954 Polyglycolide Polymers 0.000 description 1
- 229920000331 Polyhydroxybutyrate Polymers 0.000 description 1
- 108010040201 Polymyxins Proteins 0.000 description 1
- 229920001710 Polyorthoester Polymers 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 108010082714 Silver Proteins Proteins 0.000 description 1
- 229910021612 Silver iodide Inorganic materials 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 102000013275 Somatomedins Human genes 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 239000000150 Sympathomimetic Substances 0.000 description 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 description 1
- 239000004098 Tetracycline Substances 0.000 description 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 description 1
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 description 1
- 102000001742 Tumor Suppressor Proteins Human genes 0.000 description 1
- 108010040002 Tumor Suppressor Proteins Proteins 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 description 1
- 229960001138 acetylsalicylic acid Drugs 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 210000002934 adrenergic neuron Anatomy 0.000 description 1
- 239000000556 agonist Substances 0.000 description 1
- 229920003232 aliphatic polyester Polymers 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- OFCNXPDARWKPPY-UHFFFAOYSA-N allopurinol Chemical compound OC1=NC=NC2=C1C=NN2 OFCNXPDARWKPPY-UHFFFAOYSA-N 0.000 description 1
- 229960003459 allopurinol Drugs 0.000 description 1
- 229940126575 aminoglycoside Drugs 0.000 description 1
- 229940035674 anesthetics Drugs 0.000 description 1
- 230000000954 anitussive effect Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000000181 anti-adherent effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003474 anti-emetic effect Effects 0.000 description 1
- 230000003556 anti-epileptic effect Effects 0.000 description 1
- 230000001387 anti-histamine Effects 0.000 description 1
- 229940124599 anti-inflammatory drug Drugs 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000001022 anti-muscarinic effect Effects 0.000 description 1
- 230000000118 anti-neoplastic effect Effects 0.000 description 1
- 229940035678 anti-parkinson drug Drugs 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 230000000692 anti-sense effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 229940065524 anticholinergics inhalants for obstructive airway diseases Drugs 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 239000000935 antidepressant agent Substances 0.000 description 1
- 229940005513 antidepressants Drugs 0.000 description 1
- 239000002111 antiemetic agent Substances 0.000 description 1
- 229960003965 antiepileptics Drugs 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 239000003430 antimalarial agent Substances 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 229940124433 antimigraine drug Drugs 0.000 description 1
- 229940034982 antineoplastic agent Drugs 0.000 description 1
- 229940041181 antineoplastic drug Drugs 0.000 description 1
- 239000000939 antiparkinson agent Substances 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 229940125716 antipyretic agent Drugs 0.000 description 1
- 239000003434 antitussive agent Substances 0.000 description 1
- 229940124584 antitussives Drugs 0.000 description 1
- 239000003443 antiviral agent Substances 0.000 description 1
- 229940121357 antivirals Drugs 0.000 description 1
- 229960003071 bacitracin Drugs 0.000 description 1
- 229930184125 bacitracin Natural products 0.000 description 1
- CLKOFPXJLQSYAH-ABRJDSQDSA-N bacitracin A Chemical compound C1SC([C@@H](N)[C@@H](C)CC)=N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]1C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2N=CNC=2)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC1 CLKOFPXJLQSYAH-ABRJDSQDSA-N 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- 229940019700 blood coagulation factors Drugs 0.000 description 1
- 229940072440 bovine lactoferrin Drugs 0.000 description 1
- 229940124630 bronchodilator Drugs 0.000 description 1
- 239000000168 bronchodilator agent Substances 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 229920003064 carboxyethyl cellulose Polymers 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 230000024245 cell differentiation Effects 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 235000010980 cellulose Nutrition 0.000 description 1
- 229940124587 cephalosporin Drugs 0.000 description 1
- 150000001780 cephalosporins Chemical class 0.000 description 1
- 229960005091 chloramphenicol Drugs 0.000 description 1
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 description 1
- 229960002152 chlorhexidine acetate Drugs 0.000 description 1
- 229960003333 chlorhexidine gluconate Drugs 0.000 description 1
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 description 1
- 229960004504 chlorhexidine hydrochloride Drugs 0.000 description 1
- 229960001231 choline Drugs 0.000 description 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 1
- 239000000812 cholinergic antagonist Substances 0.000 description 1
- 229960003405 ciprofloxacin Drugs 0.000 description 1
- 239000008199 coating composition Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 229960004126 codeine Drugs 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 229960005188 collagen Drugs 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 239000003218 coronary vasodilator agent Substances 0.000 description 1
- 231100000433 cytotoxic Toxicity 0.000 description 1
- 230000001472 cytotoxic effect Effects 0.000 description 1
- 239000000850 decongestant Substances 0.000 description 1
- 229940124581 decongestants Drugs 0.000 description 1
- XLMALTXPSGQGBX-GCJKJVERSA-N dextropropoxyphene Chemical compound C([C@](OC(=O)CC)([C@H](C)CN(C)C)C=1C=CC=CC=1)C1=CC=CC=C1 XLMALTXPSGQGBX-GCJKJVERSA-N 0.000 description 1
- 229960004193 dextropropoxyphene Drugs 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 229940030606 diuretics Drugs 0.000 description 1
- 239000012636 effector Substances 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 229920002549 elastin Polymers 0.000 description 1
- 239000002158 endotoxin Substances 0.000 description 1
- IDYZIJYBMGIQMJ-UHFFFAOYSA-N enoxacin Chemical compound N1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCNCC1 IDYZIJYBMGIQMJ-UHFFFAOYSA-N 0.000 description 1
- 229960002549 enoxacin Drugs 0.000 description 1
- 229940105423 erythropoietin Drugs 0.000 description 1
- 229940011871 estrogen Drugs 0.000 description 1
- 239000000262 estrogen Substances 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000002871 fertility agent Substances 0.000 description 1
- 229950003499 fibrin Drugs 0.000 description 1
- 229940012952 fibrinogen Drugs 0.000 description 1
- 238000010304 firing Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 229960004675 fusidic acid Drugs 0.000 description 1
- IECPWNUMDGFDKC-MZJAQBGESA-N fusidic acid Chemical compound O[C@@H]([C@@H]12)C[C@H]3\C(=C(/CCC=C(C)C)C(O)=O)[C@@H](OC(C)=O)C[C@]3(C)[C@@]2(C)CC[C@@H]2[C@]1(C)CC[C@@H](O)[C@H]2C IECPWNUMDGFDKC-MZJAQBGESA-N 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 239000004083 gastrointestinal agent Substances 0.000 description 1
- 229940127227 gastrointestinal drug Drugs 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229940014259 gelatin Drugs 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000003193 general anesthetic agent Substances 0.000 description 1
- 229960002518 gentamicin Drugs 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 229960003711 glyceryl trinitrate Drugs 0.000 description 1
- 239000002622 gonadotropin Substances 0.000 description 1
- 230000003394 haemopoietic effect Effects 0.000 description 1
- 230000002439 hemostatic effect Effects 0.000 description 1
- 229920001519 homopolymer Polymers 0.000 description 1
- 239000002944 hormone and hormone analog Substances 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- LLPOLZWFYMWNKH-CMKMFDCUSA-N hydrocodone Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)CC(=O)[C@@H]1OC1=C2C3=CC=C1OC LLPOLZWFYMWNKH-CMKMFDCUSA-N 0.000 description 1
- 229960000240 hydrocodone Drugs 0.000 description 1
- OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 description 1
- 229960000890 hydrocortisone Drugs 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 1
- 239000003326 hypnotic agent Substances 0.000 description 1
- 230000000147 hypnotic effect Effects 0.000 description 1
- 102000018358 immunoglobulin Human genes 0.000 description 1
- 229940072221 immunoglobulins Drugs 0.000 description 1
- 229960003444 immunosuppressant agent Drugs 0.000 description 1
- 239000003018 immunosuppressive agent Substances 0.000 description 1
- 229960000905 indomethacin Drugs 0.000 description 1
- 229940125699 infertility agent Drugs 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 229940047124 interferons Drugs 0.000 description 1
- 229940047122 interleukins Drugs 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 238000009940 knitting Methods 0.000 description 1
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 229920006008 lipopolysaccharide Polymers 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000003589 local anesthetic agent Substances 0.000 description 1
- 229960005015 local anesthetics Drugs 0.000 description 1
- 229960002509 miconazole Drugs 0.000 description 1
- 229960005181 morphine Drugs 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 239000003149 muscarinic antagonist Substances 0.000 description 1
- 229940035363 muscle relaxants Drugs 0.000 description 1
- 239000003158 myorelaxant agent Substances 0.000 description 1
- IFVGFQAONSKBCR-UHFFFAOYSA-N n-[bis(aziridin-1-yl)phosphoryl]pyrimidin-2-amine Chemical compound C1CN1P(N1CC1)(=O)NC1=NC=CC=N1 IFVGFQAONSKBCR-UHFFFAOYSA-N 0.000 description 1
- MHWLWQUZZRMNGJ-UHFFFAOYSA-N nalidixic acid Chemical compound C1=C(C)N=C2N(CC)C=C(C(O)=O)C(=O)C2=C1 MHWLWQUZZRMNGJ-UHFFFAOYSA-N 0.000 description 1
- 229960000210 nalidixic acid Drugs 0.000 description 1
- UZHSEJADLWPNLE-GRGSLBFTSA-N naloxone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(O)C2=C5[C@@]13CCN4CC=C UZHSEJADLWPNLE-GRGSLBFTSA-N 0.000 description 1
- 229960004127 naloxone Drugs 0.000 description 1
- DQCKKXVULJGBQN-XFWGSAIBSA-N naltrexone Chemical compound N1([C@@H]2CC3=CC=C(C=4O[C@@H]5[C@](C3=4)([C@]2(CCC5=O)O)CC1)O)CC1CC1 DQCKKXVULJGBQN-XFWGSAIBSA-N 0.000 description 1
- 229960003086 naltrexone Drugs 0.000 description 1
- 239000004081 narcotic agent Substances 0.000 description 1
- 230000003533 narcotic effect Effects 0.000 description 1
- 229960004927 neomycin Drugs 0.000 description 1
- 230000001613 neoplastic effect Effects 0.000 description 1
- 229940053128 nerve growth factor Drugs 0.000 description 1
- 229940087419 nonoxynol-9 Drugs 0.000 description 1
- 229920004918 nonoxynol-9 Polymers 0.000 description 1
- 229960001180 norfloxacin Drugs 0.000 description 1
- OGJPXUAPXNRGGI-UHFFFAOYSA-N norfloxacin Chemical compound C1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCNCC1 OGJPXUAPXNRGGI-UHFFFAOYSA-N 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 229960001019 oxacillin Drugs 0.000 description 1
- UWYHMGVUTGAWSP-JKIFEVAISA-N oxacillin Chemical compound N([C@@H]1C(N2[C@H](C(C)(C)S[C@@H]21)C(O)=O)=O)C(=O)C1=C(C)ON=C1C1=CC=CC=C1 UWYHMGVUTGAWSP-JKIFEVAISA-N 0.000 description 1
- 229960005434 oxybutynin Drugs 0.000 description 1
- 229960005489 paracetamol Drugs 0.000 description 1
- 239000000734 parasympathomimetic agent Substances 0.000 description 1
- 229960004236 pefloxacin Drugs 0.000 description 1
- FHFYDNQZQSQIAI-UHFFFAOYSA-N pefloxacin Chemical compound C1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCN(C)CC1 FHFYDNQZQSQIAI-UHFFFAOYSA-N 0.000 description 1
- 150000002960 penicillins Chemical class 0.000 description 1
- 229960000482 pethidine Drugs 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 229960002895 phenylbutazone Drugs 0.000 description 1
- VYMDGNCVAMGZFE-UHFFFAOYSA-N phenylbutazonum Chemical compound O=C1C(CCCC)C(=O)N(C=2C=CC=CC=2)N1C1=CC=CC=C1 VYMDGNCVAMGZFE-UHFFFAOYSA-N 0.000 description 1
- WCMIIGXFCMNQDS-IDYPWDAWSA-M piperacillin sodium Chemical compound [Na+].O=C1C(=O)N(CC)CCN1C(=O)N[C@H](C=1C=CC=CC=1)C(=O)N[C@@H]1C(=O)N2[C@@H](C([O-])=O)C(C)(C)S[C@@H]21 WCMIIGXFCMNQDS-IDYPWDAWSA-M 0.000 description 1
- 229940099765 pipracil Drugs 0.000 description 1
- 229920001308 poly(aminoacid) Polymers 0.000 description 1
- 239000005015 poly(hydroxybutyrate) Substances 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 239000002745 poly(ortho ester) Substances 0.000 description 1
- 229920002627 poly(phosphazenes) Polymers 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920001610 polycaprolactone Polymers 0.000 description 1
- 239000004632 polycaprolactone Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229940041153 polymyxins Drugs 0.000 description 1
- 108091033319 polynucleotide Proteins 0.000 description 1
- 102000040430 polynucleotide Human genes 0.000 description 1
- 239000002157 polynucleotide Substances 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 description 1
- 229960005205 prednisolone Drugs 0.000 description 1
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 description 1
- 229960004618 prednisone Drugs 0.000 description 1
- XOFYZVNMUHMLCC-ZPOLXVRWSA-N prednisone Chemical compound O=C1C=C[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 XOFYZVNMUHMLCC-ZPOLXVRWSA-N 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- MCSINKKTEDDPNK-UHFFFAOYSA-N propyl propionate Chemical compound CCCOC(=O)CC MCSINKKTEDDPNK-UHFFFAOYSA-N 0.000 description 1
- 150000003180 prostaglandins Chemical class 0.000 description 1
- 229940076372 protein antagonist Drugs 0.000 description 1
- 229940121649 protein inhibitor Drugs 0.000 description 1
- 239000012268 protein inhibitor Substances 0.000 description 1
- 150000007660 quinolones Chemical class 0.000 description 1
- 108091092562 ribozyme Proteins 0.000 description 1
- 229960001225 rifampicin Drugs 0.000 description 1
- JQXXHWHPUNPDRT-WLSIYKJHSA-N rifampicin Chemical compound O([C@](C1=O)(C)O/C=C/[C@@H]([C@H]([C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)\C=C\C=C(C)/C(=O)NC=2C(O)=C3C([O-])=C4C)C)OC)C4=C1C3=C(O)C=2\C=N\N1CC[NH+](C)CC1 JQXXHWHPUNPDRT-WLSIYKJHSA-N 0.000 description 1
- 238000010079 rubber tapping Methods 0.000 description 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 description 1
- 229960001860 salicylate Drugs 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 229940125723 sedative agent Drugs 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- CQLFBEKRDQMJLZ-UHFFFAOYSA-M silver acetate Chemical compound [Ag+].CC([O-])=O CQLFBEKRDQMJLZ-UHFFFAOYSA-M 0.000 description 1
- 229940071536 silver acetate Drugs 0.000 description 1
- LKZMBDSASOBTPN-UHFFFAOYSA-L silver carbonate Substances [Ag].[O-]C([O-])=O LKZMBDSASOBTPN-UHFFFAOYSA-L 0.000 description 1
- 229910001958 silver carbonate Inorganic materials 0.000 description 1
- 229940071575 silver citrate Drugs 0.000 description 1
- YSVXTGDPTJIEIX-UHFFFAOYSA-M silver iodate Chemical compound [Ag+].[O-]I(=O)=O YSVXTGDPTJIEIX-UHFFFAOYSA-M 0.000 description 1
- 229940045105 silver iodide Drugs 0.000 description 1
- 229910001961 silver nitrate Inorganic materials 0.000 description 1
- 229910001923 silver oxide Inorganic materials 0.000 description 1
- 229960003600 silver sulfadiazine Drugs 0.000 description 1
- UEJSSZHHYBHCEL-UHFFFAOYSA-N silver(1+) sulfadiazinate Chemical compound [Ag+].C1=CC(N)=CC=C1S(=O)(=O)[N-]C1=NC=CC=N1 UEJSSZHHYBHCEL-UHFFFAOYSA-N 0.000 description 1
- LMEWRZSPCQHBOB-UHFFFAOYSA-M silver;2-hydroxypropanoate Chemical compound [Ag+].CC(O)C([O-])=O LMEWRZSPCQHBOB-UHFFFAOYSA-M 0.000 description 1
- CLDWGXZGFUNWKB-UHFFFAOYSA-M silver;benzoate Chemical compound [Ag+].[O-]C(=O)C1=CC=CC=C1 CLDWGXZGFUNWKB-UHFFFAOYSA-M 0.000 description 1
- MNMYRUHURLPFQW-UHFFFAOYSA-M silver;dodecanoate Chemical compound [Ag+].CCCCCCCCCCCC([O-])=O MNMYRUHURLPFQW-UHFFFAOYSA-M 0.000 description 1
- LTYHQUJGIQUHMS-UHFFFAOYSA-M silver;hexadecanoate Chemical compound [Ag+].CCCCCCCCCCCCCCCC([O-])=O LTYHQUJGIQUHMS-UHFFFAOYSA-M 0.000 description 1
- 230000003637 steroidlike Effects 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- 239000003356 suture material Substances 0.000 description 1
- 230000002889 sympathetic effect Effects 0.000 description 1
- 230000001975 sympathomimetic effect Effects 0.000 description 1
- 229940064707 sympathomimetics Drugs 0.000 description 1
- FBWNMEQMRUMQSO-UHFFFAOYSA-N tergitol NP-9 Chemical compound CCCCCCCCCC1=CC=C(OCCOCCOCCOCCOCCOCCOCCOCCOCCO)C=C1 FBWNMEQMRUMQSO-UHFFFAOYSA-N 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000008467 tissue growth Effects 0.000 description 1
- 229960000707 tobramycin Drugs 0.000 description 1
- NLVFBUXFDBBNBW-PBSUHMDJSA-N tobramycin Chemical compound N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N NLVFBUXFDBBNBW-PBSUHMDJSA-N 0.000 description 1
- 239000003204 tranquilizing agent Substances 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 229960003500 triclosan Drugs 0.000 description 1
- QUTYHQJYVDNJJA-UHFFFAOYSA-K trisilver;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [Ag+].[Ag+].[Ag+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O QUTYHQJYVDNJJA-UHFFFAOYSA-K 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 238000009941 weaving Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
- A61B17/072—Surgical staplers, e.g. containing multiple staples or clamps for applying a row of staples in a single action, e.g. the staples being applied simultaneously
- A61B17/07292—Reinforcements for staple line, e.g. pledgets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
- A61B17/072—Surgical staplers, e.g. containing multiple staples or clamps for applying a row of staples in a single action, e.g. the staples being applied simultaneously
- A61B17/07207—Surgical staplers, e.g. containing multiple staples or clamps for applying a row of staples in a single action, e.g. the staples being applied simultaneously the staples being applied sequentially
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00884—Material properties enhancing wound closure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00893—Material properties pharmaceutically effective
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
- A61B17/072—Surgical staplers, e.g. containing multiple staples or clamps for applying a row of staples in a single action, e.g. the staples being applied simultaneously
- A61B2017/07214—Stapler heads
- A61B2017/07271—Stapler heads characterised by its cartridge
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
Abstract
Description
本開示は、ステープルラインバットレス材料のための保持アセンブリに関し、より具体的には、外科用ステープル留め装置にステープルラインバットレス材料を着脱可能に固定または保持するためのアセンブリおよび方法に関する。
例えば、本願は以下の項目を提供する。
(項目1)
作動トリガーを含むハンドルと、
上記ハンドルに動作可能に結合されたツールアセンブリであって、上記ツールアセンブリが、第1の顎部材と第2の顎部材とを含む、ツールアセンブリと、
バットレス保持アセンブリであって、
上記第1の顎部材と着脱可能に結合されるように構成されたスリーブであって、上記スリーブが、近位部分および遠位部分を含み、上記近位部分が、上記近位部分の少なくとも1つの側面から横方向外方に延在する近位フックを含み、上記遠位部分が、開口部を画定する口を含み、上記口が、上記第1の顎部材のナイフスロットに少なくとも部分的に受容されるように構成されたフックを含み、上記口が、内方に延在するボスを有する内面を含む、スリーブと、
近位端部分および遠位端部分を含むバットレス材料であって、上記バットレス材料が、上記近位端部分の側面から横方向外方に延在するタブを含み、上記タブが、上記スリーブの上記近位フックを受容するように構成された近位スロットを画定し、上記遠位端部分の少なくとも一部が、上記スリーブの上記口の上記開口部を通って延在し、上記遠位端部分が、上記スリーブの上記ボスを受容するように寸法決めされた遠位スロットを画定する、バットレス材料と、を含む、バットレス保持アセンブリと、を備える、外科用ステープル留め装置。
(項目2)
上記バットレス材料が、上記バットレス材料が上記スリーブ上で支持されたときに、上記ツールアセンブリのナイフで上記バットレス材料をその長さに沿って切断することにより、上記口の上記フックが上記バットレス材料を上記第1の顎部材の上記ナイフスロットに向かって内方に押しやり、これにより、上記スリーブの上記ボスが上記バットレス材料の上記遠位スロットから解放されるように、弾性材料で形成される、上記項目に記載の外科用ステープル留め装置。
(項目3)
上記バットレス材料の上記近位端部分が、上記ツールアセンブリのナイフを受容するように寸法決めされたスリットを画定する、上記項目のいずれか一項に記載の外科用ステープル留め装置。
(項目4)
上記スリーブが、上記第1の顎部材を受容するように構成された弓状の形状を含む、上記項目のいずれか一項に記載の外科用ステープル留め装置。
(項目5)
上記スリーブの上記近位部分が、上記第1の顎部材と係合するために、その対向する側面から横方向外方に延在する複数のリップを含む、上記項目のいずれか一項に記載の外科用ステープル留め装置。
(項目6)
上記スリーブの上記近位部分が、上記スリーブの上記近位部分の上記対向する側面に配置された複数の近位フックを含む、上記項目のいずれか一項に記載の外科用ステープル留め装置。
(項目7)
各近位フックが、隣接するリップの間に挿入される、上記項目のいずれか一項に記載の外科用ステープル留め装置。
(項目8)
上記スリーブが、スナップ嵌めまたは締まり嵌め構成によって上記第1の顎部材に固定される、上記項目のいずれか一項に記載の外科用ステープル留め装置。
(項目9)
上記スリーブの上記口が、側面を有する鼻を含み、上記側面が、上記鼻の上記側面が互いに圧迫されたときに、上記アンビルから離れるように上記スリーブの上記フックを変位するように構成されている、上記項目のいずれか一項に記載の外科用ステープル留め装置。
(項目10)
上記口が、上記アンビルによって画定された長手方向軸に対して鋭角を画定する内面を含む、上記項目のいずれか一項に記載の外科用ステープル留め装置。
(項目11)
上記ボスが、上記口の上記内面から延在する、上記項目のいずれか一項に記載の外科用ステープル留め装置。
(項目12)
外科用ステープル留め装置とともに使用するバットレス保持アセンブリであって、
上記外科用ステープル留め装置の顎部材上に支持されるように寸法決めされたバットレス材料と、
上記外科用ステープル留め装置の上記顎部材の遠位部分を受容するように構成された第1のチャネル、および上記第1のチャネルと重ねられた関係にある第2のチャネルを画定する基部と、
上記第2のチャネルに摺動可能に収容されるように寸法決めされたスライダーであって、上記基部が、上記スライダーが上記基部の上記第2のチャネルに完全に収容されると、上記スライダーが上記バットレス材料の一部および上記顎部材の上記遠位部分をその中に固定するように、上記第1のチャネルの寸法を小さくするために、上記第1のチャネルに圧力を加えるように、弾性材料で形成される、スライダーと、を備える、バットレス保持アセンブリ。
(項目13)
上記スライダーが、上記外科用ステープル留め装置のナイフ部材と係合するように構成された細長い係合部分を含む、上記項目に記載のバットレス保持アセンブリ。
(項目14)
上記スライダーが、上記基部の上記第2のチャネルに受容されるように構成されたテーパー部分を含む、上記項目のいずれか一項に記載のバットレス保持アセンブリ。
(項目15)
上記第2のチャネルが、上記スライダーの上記テーパー部分を補完するテーパー形状を有する、上記項目のいずれか一項に記載のバットレス保持アセンブリ。
(項目16)
外科用ステープル留め装置とともに使用するバットレス保持アセンブリであって、
上記外科用ステープル留め装置の顎部材上に支持されるように寸法決めされたバットレス材料と、
上記バットレス材料の一部および上記外科用ステープル留め装置の上記顎部材の遠位部分を受容するように構成された第1のスロットを画定する基部と、
上記基部に枢動可能に装着されたレバーであって、上記レバーが、上記バットレス材料および上記顎部材の上記遠位部分を上記第1のスロットに固定するために、上記レバーが上記第1のスロット内に配置された上記バットレス材料および上記顎部材の上記遠位部分に圧力を与えるロック状態と、上記バットレス材料および上記顎部材の上記遠位部分が上記第1のスロットに解放可能に配置される解放位置との間で移行可能である、レバーと、を備える、バットレス保持アセンブリ。
(項目17)
上記基部が、上記顎部材のナイフスロットに受容されるように寸法決めされた指を含むフック部分を含む、上記項目に記載のバットレス保持アセンブリ。
(項目18)
上記フック部分が、上記指に直交する方向に向いた横断部材を含む、上記項目のいずれか一項に記載のバットレス保持アセンブリ。
(項目19)
上記第1のスロットが、上記バットレス材料および上記顎部材の上記遠位部分を、中を通して回転可能に受容するための横方向開口部を含む、上記項目のいずれか一項に記載のバットレス保持アセンブリ。
(項目20)
上記基部が、可撓性材料で形成される、上記項目のいずれか一項に記載のバットレス保持アセンブリ。
(摘要)
外科用ステープル留め装置は、バットレス保持アセンブリを含む。バットレス保持アセンブリは、外科用ステープル留め装置のツールアセンブリの第1の顎部材と着脱可能に結合されるように構成されたスリーブと、バットレス材料とを含む。スリーブは、スリーブの側面から横方向外方に延在する近位フックと、第1の顎部材のナイフスロットに受容されるように構成されたフックを含む口とを含む。口は、内方に延在するボスを有する内面を含む。バットレス材料は、その側面から横方向外方に延在するタブを含む。タブは、スリーブの近位フックを受容するように構成された近位スロットを画定する。遠位端部分の少なくとも一部は、スリーブの口を通って延在する。遠位端部分は、スリーブのボスを受容するように寸法決めされた遠位スロットを画定する。
Claims (20)
- 作動トリガーを含むハンドルと、
前記ハンドルに動作可能に結合されたツールアセンブリであって、前記ツールアセンブリが、第1の顎部材と第2の顎部材とを含む、ツールアセンブリと、
バットレス保持アセンブリであって、
前記第1の顎部材と着脱可能に結合されるように構成されたスリーブであって、前記スリーブが、近位部分および遠位部分を含み、前記近位部分が、前記近位部分の少なくとも1つの側面から横方向外方に延在する近位フックを含み、前記遠位部分が、開口部を画定する口を含み、前記口が、前記第1の顎部材のナイフスロットに少なくとも部分的に受容されるように構成されたフックを含み、前記口が、内方に延在するボスを有する内面を含む、スリーブと、
近位端部分および遠位端部分を含むバットレス材料であって、前記バットレス材料が、前記近位端部分の側面から横方向外方に延在するタブを含み、前記タブが、前記スリーブの前記近位フックを受容するように構成された近位スロットを画定し、前記遠位端部分の少なくとも一部が、前記スリーブの前記口の前記開口部を通って延在し、前記遠位端部分が、前記スリーブの前記ボスを受容するように寸法決めされた遠位スロットを画定する、バットレス材料と、を含む、バットレス保持アセンブリと、を備える、外科用ステープル留め装置。 - 前記バットレス材料が、前記バットレス材料が前記スリーブ上で支持されたときに、前記ツールアセンブリのナイフで前記バットレス材料をその長さに沿って切断することにより、前記口の前記フックが前記バットレス材料を前記第1の顎部材の前記ナイフスロットに向かって内方に押しやり、これにより、前記スリーブの前記ボスが前記バットレス材料の前記遠位スロットから解放されるように、弾性材料で形成される、請求項1に記載の外科用ステープル留め装置。
- 前記バットレス材料の前記近位端部分が、前記ツールアセンブリのナイフを受容するように寸法決めされたスリットを画定する、請求項1に記載の外科用ステープル留め装置。
- 前記スリーブが、前記第1の顎部材を受容するように構成された弓状の形状を含む、請求項1に記載の外科用ステープル留め装置。
- 前記スリーブの前記近位部分が、前記第1の顎部材と係合するために、その対向する側面から横方向外方に延在する複数のリップを含む、請求項1に記載の外科用ステープル留め装置。
- 前記スリーブの前記近位部分が、前記スリーブの前記近位部分の前記対向する側面に配置された複数の近位フックを含む、請求項5に記載の外科用ステープル留め装置。
- 各近位フックが、隣接するリップの間に挿入される、請求項5に記載の外科用ステープル留め装置。
- 前記スリーブが、スナップ嵌めまたは締まり嵌め構成によって前記第1の顎部材に固定される、請求項1に記載の外科用ステープル留め装置。
- 前記スリーブの前記口が、側面を有する鼻を含み、前記側面が、前記鼻の前記側面が互いに圧迫されたときに、前記アンビルから離れるように前記スリーブの前記フックを変位するように構成されている、請求項1に記載の外科用ステープル留め装置。
- 前記口が、前記アンビルによって画定された長手方向軸に対して鋭角を画定する内面を含む、請求項1に記載の外科用ステープル留め装置。
- 前記ボスが、前記口の前記内面から延在する、請求項10に記載の外科用ステープル留め装置。
- 外科用ステープル留め装置とともに使用するバットレス保持アセンブリであって、
前記外科用ステープル留め装置の顎部材上に支持されるように寸法決めされたバットレス材料と、
前記外科用ステープル留め装置の前記顎部材の遠位部分を受容するように構成された第1のチャネル、および前記第1のチャネルと重ねられた関係にある第2のチャネルを画定する基部と、
前記第2のチャネルに摺動可能に収容されるように寸法決めされたスライダーであって、前記基部が、前記スライダーが前記基部の前記第2のチャネルに完全に収容されると、前記スライダーが前記バットレス材料の一部および前記顎部材の前記遠位部分をその中に固定するように、前記第1のチャネルの寸法を小さくするために、前記第1のチャネルに圧力を加えるように、弾性材料で形成される、スライダーと、を備える、バットレス保持アセンブリ。 - 前記スライダーが、前記外科用ステープル留め装置のナイフ部材と係合するように構成された細長い係合部分を含む、請求項12に記載のバットレス保持アセンブリ。
- 前記スライダーが、前記基部の前記第2のチャネルに受容されるように構成されたテーパー部分を含む、請求項12に記載のバットレス保持アセンブリ。
- 前記第2のチャネルが、前記スライダーの前記テーパー部分を補完するテーパー形状を有する、請求項14に記載のバットレス保持アセンブリ。
- 外科用ステープル留め装置とともに使用するバットレス保持アセンブリであって、
前記外科用ステープル留め装置の顎部材上に支持されるように寸法決めされたバットレス材料と、
前記バットレス材料の一部および前記外科用ステープル留め装置の前記顎部材の遠位部分を受容するように構成された第1のスロットを画定する基部と、
前記基部に枢動可能に装着されたレバーであって、前記レバーが、前記バットレス材料および前記顎部材の前記遠位部分を前記第1のスロットに固定するために、前記レバーが前記第1のスロット内に配置された前記バットレス材料および前記顎部材の前記遠位部分に圧力を与えるロック状態と、前記バットレス材料および前記顎部材の前記遠位部分が前記第1のスロットに解放可能に配置される解放位置との間で移行可能である、レバーと、を備える、バットレス保持アセンブリ。 - 前記基部が、前記顎部材のナイフスロットに受容されるように寸法決めされた指を含むフック部分を含む、請求項16に記載のバットレス保持アセンブリ。
- 前記フック部分が、前記指に直交する方向に向いた横断部材を含む、請求項17に記載のバットレス保持アセンブリ。
- 前記第1のスロットが、前記バットレス材料および前記顎部材の前記遠位部分を、中を通して回転可能に受容するための横方向開口部を含む、請求項16に記載のバットレス保持アセンブリ。
- 前記基部が、可撓性材料で形成される、請求項16に記載のバットレス保持アセンブリ。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16/150,301 US10952729B2 (en) | 2018-10-03 | 2018-10-03 | Universal linear buttress retention/release assemblies and methods |
US16/150,301 | 2018-10-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2020054808A true JP2020054808A (ja) | 2020-04-09 |
JP7393165B2 JP7393165B2 (ja) | 2023-12-06 |
Family
ID=68136196
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019169322A Active JP7393165B2 (ja) | 2018-10-03 | 2019-09-18 | 汎用線形バットレス保持/解放アセンブリおよび方法 |
Country Status (6)
Country | Link |
---|---|
US (2) | US10952729B2 (ja) |
EP (1) | EP3632342B1 (ja) |
JP (1) | JP7393165B2 (ja) |
AU (1) | AU2019222817A1 (ja) |
CA (1) | CA3053111A1 (ja) |
ES (1) | ES2886205T3 (ja) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10952729B2 (en) | 2018-10-03 | 2021-03-23 | Covidien Lp | Universal linear buttress retention/release assemblies and methods |
US11707276B2 (en) * | 2020-09-08 | 2023-07-25 | Covidien Lp | Surgical buttress assemblies and techniques for surgical stapling |
US11419605B2 (en) | 2020-09-16 | 2022-08-23 | Cilag Gmbh International | Apparatus and method to close end effector of surgical stapler onto buttress |
US11660093B2 (en) | 2020-09-16 | 2023-05-30 | Cilag Gmbh International | Method of applying buttress to end effector of surgical stapler |
US11766261B2 (en) | 2020-09-16 | 2023-09-26 | Cilag Gmbh International | Apparatus and method to apply buttress to end effector of surgical stapler via fixed base |
US11452523B2 (en) | 2020-09-16 | 2022-09-27 | Cilag Gmbh International | Apparatus and method to apply buttresses separately to jaws of end effector of surgical stapler |
US11413040B2 (en) | 2020-09-16 | 2022-08-16 | Cilag Gmbh International | Apparatus and method to apply buttress to end effector of surgical stapler with authentication |
US11559306B2 (en) | 2020-09-16 | 2023-01-24 | Cilag Gmbh International | Apparatus and method to detect full seating of buttress applicator in end effector of surgical stapler |
US11564683B2 (en) | 2020-09-16 | 2023-01-31 | Cilag Gmbh International | Apparatus and method to apply buttress to end effector of surgical stapler via driven member |
US11399833B2 (en) * | 2020-10-19 | 2022-08-02 | Covidien Lp | Anvil buttress attachment for surgical stapling apparatus |
US11596399B2 (en) * | 2021-06-23 | 2023-03-07 | Covidien Lp | Anvil buttress attachment for surgical stapling apparatus |
US20230036899A1 (en) * | 2021-08-02 | 2023-02-02 | Covidien Lp | Surgical stapling device with extrusion resistant tool assembly |
US20230040425A1 (en) * | 2021-08-03 | 2023-02-09 | Covidien Lp | Surgical buttress attachment assemblies for surgical stapling apparatus |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003000603A (ja) * | 2001-05-07 | 2003-01-07 | Ethicon Endo Surgery Inc | 外科用組織ステープリング器具及び外科用ステープリング器具へのバットレス材料の取付け組立体 |
JP2010142636A (ja) * | 2008-12-16 | 2010-07-01 | Tyco Healthcare Group Lp | 外科用バットレスを含む外科用装置 |
JP2014018666A (ja) * | 2012-07-18 | 2014-02-03 | Covidien Lp | 外科用バットレスを含む外科用装置 |
WO2018152102A1 (en) * | 2017-02-17 | 2018-08-23 | Ethicon Llc | Hybrid mechanism for attachment of an adjunct to a surgical instrument |
US20180256164A1 (en) * | 2017-03-09 | 2018-09-13 | Covidien Lp | Structure for attaching buttress material to anvil and cartridge of surgical stapling instrument |
Family Cites Families (385)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3124136A (en) | 1964-03-10 | Method of repairing body tissue | ||
DE1602563U (de) | 1949-08-01 | 1950-03-02 | Lebrecht Langenohl | S-foermiger, federnder fraeser zum reinigen von tabakpfeifenkoepfen. |
US3054406A (en) | 1958-10-17 | 1962-09-18 | Phillips Petroleum Co | Surgical mesh |
US3079606A (en) | 1960-01-04 | 1963-03-05 | Bobrov Boris Sergeevich | Instrument for placing lateral gastrointestinal anastomoses |
US3364200A (en) | 1960-03-28 | 1968-01-16 | Johnson & Johnson | Oxidized cellulose product and method for preparing the same |
US3490675A (en) | 1966-10-10 | 1970-01-20 | United States Surgical Corp | Instrument for placing lateral gastrointestinal anastomoses |
US3499591A (en) | 1967-06-23 | 1970-03-10 | United States Surgical Corp | Instrument for placing lateral gastro-intestinal anastomoses |
US3797494A (en) | 1969-04-01 | 1974-03-19 | Alza Corp | Bandage for the administration of drug by controlled metering through microporous materials |
DE2415728A1 (de) | 1973-04-13 | 1975-01-02 | Teijin Ltd | Traegerfuer fluessiges lichtempfindliches hharz |
US3939068A (en) | 1973-12-06 | 1976-02-17 | The United States Of America As Represented By The Secretary Of The Army | Process for treating waste water containing cellulose nitrate particles |
US4064062A (en) | 1975-12-15 | 1977-12-20 | Colgate-Palmolive | Stabilized activated percompound bleaching compositions and methods for manufacture thereof |
US4416698A (en) | 1977-07-26 | 1983-11-22 | Akzona Incorporated | Shaped cellulose article prepared from a solution containing cellulose dissolved in a tertiary amine N-oxide solvent and a process for making the article |
US4166800A (en) | 1977-08-25 | 1979-09-04 | Sandoz, Inc. | Processes for preparation of microspheres |
US4282236A (en) | 1979-11-07 | 1981-08-04 | Beecham Group Limited | β-Lactam antibacterial agents, their use in pharmaceutical compositions, and intermediates |
US4429695A (en) | 1980-02-05 | 1984-02-07 | United States Surgical Corporation | Surgical instruments |
US4452245A (en) | 1980-06-06 | 1984-06-05 | Usher Francis C | Surgical mesh and method |
US4347847A (en) | 1980-06-06 | 1982-09-07 | Usher Francis C | Method of hernia repair |
US4354628A (en) | 1980-09-29 | 1982-10-19 | United States Surgical Corporation | Surgical stapler apparatus having pivotally related staple holder and anvil |
US4605730A (en) | 1982-10-01 | 1986-08-12 | Ethicon, Inc. | Surgical articles of copolymers of glycolide and ε-caprolactone and methods of producing the same |
US4633873A (en) | 1984-04-26 | 1987-01-06 | American Cyanamid Company | Surgical repair mesh |
US4626253A (en) | 1984-10-05 | 1986-12-02 | Johnson & Johnson Products, Inc. | Surgical hemostat comprising oxidized cellulose |
US4655221A (en) | 1985-05-06 | 1987-04-07 | American Cyanamid Company | Method of using a surgical repair mesh |
US5002551A (en) | 1985-08-22 | 1991-03-26 | Johnson & Johnson Medical, Inc. | Method and material for prevention of surgical adhesions |
SE450087B (sv) | 1985-10-11 | 1987-06-09 | Haessle Ab | Korn med kontrollerad frisettning av farmaceutiskt aktiva emnen som anbringats teckande pa ett kompakt olosligt kernmaterial |
US4834090A (en) | 1987-03-02 | 1989-05-30 | Moore J Paul | Suture boot |
US5285944A (en) | 1987-05-26 | 1994-02-15 | United States Surgical Corporation | Surgical stapler apparatus |
CA1335527C (en) | 1988-02-01 | 1995-05-16 | Arnold Lee Dellon | Bioabsorbable surgical device for treating nerve defects |
US5112496A (en) | 1988-11-02 | 1992-05-12 | Petrolite Corporation | Methods for inhibition of scale in high brine environments |
WO1990005489A1 (en) | 1988-11-18 | 1990-05-31 | Immuno Sweden Ab | Instrument for anastomosis |
US5162430A (en) | 1988-11-21 | 1992-11-10 | Collagen Corporation | Collagen-polymer conjugates |
US5550187A (en) | 1988-11-21 | 1996-08-27 | Collagen Corporation | Method of preparing crosslinked biomaterial compositions for use in tissue augmentation |
US5306500A (en) | 1988-11-21 | 1994-04-26 | Collagen Corporation | Method of augmenting tissue with collagen-polymer conjugates |
US4930674A (en) | 1989-02-24 | 1990-06-05 | Abiomed, Inc. | Surgical stapler |
US5413268A (en) * | 1989-05-26 | 1995-05-09 | United States Surgical Corporation | Apparatus and method for placing stables in laparoscopic or endoscopic procedures |
US5040715B1 (en) | 1989-05-26 | 1994-04-05 | United States Surgical Corp | Apparatus and method for placing staples in laparoscopic or endoscopic procedures |
US5318221A (en) | 1989-05-26 | 1994-06-07 | United States Surgical Corporation | Apparatus and method for placing staples in laparoscopic or endoscopic procedures |
US5014899A (en) | 1990-03-30 | 1991-05-14 | United States Surgical Corporation | Surgical stapling apparatus |
US5057334A (en) | 1990-07-13 | 1991-10-15 | Ort's Inc. | Process for recovery of cellulose |
US5410016A (en) | 1990-10-15 | 1995-04-25 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
US5344454A (en) | 1991-07-24 | 1994-09-06 | Baxter International Inc. | Closed porous chambers for implanting tissue in a host |
US5314471A (en) | 1991-07-24 | 1994-05-24 | Baxter International Inc. | Tissue inplant systems and methods for sustaining viable high cell densities within a host |
US5690675A (en) | 1991-02-13 | 1997-11-25 | Fusion Medical Technologies, Inc. | Methods for sealing of staples and other fasteners in tissue |
US5065929A (en) | 1991-04-01 | 1991-11-19 | Ethicon, Inc. | Surgical stapler with locking means |
US6773458B1 (en) | 1991-07-24 | 2004-08-10 | Baxter International Inc. | Angiogenic tissue implant systems and methods |
GR920100358A (el) | 1991-08-23 | 1993-06-07 | Ethicon Inc | Οργανο συρραφής χειρουργικής αναστομώσεως. |
CA2075141C (en) | 1991-10-17 | 1998-06-30 | Donald A. Morin | Anvil for surgical staplers |
US5326013A (en) | 1991-10-18 | 1994-07-05 | United States Surgical Corporation | Self contained gas powered surgical apparatus |
US5312023A (en) | 1991-10-18 | 1994-05-17 | United States Surgical Corporation | Self contained gas powered surgical apparatus |
US5307976A (en) | 1991-10-18 | 1994-05-03 | Ethicon, Inc. | Linear stapling mechanism with cutting means |
US5332142A (en) | 1991-10-18 | 1994-07-26 | Ethicon, Inc. | Linear stapling mechanism with cutting means |
US5443198A (en) | 1991-10-18 | 1995-08-22 | United States Surgical Corporation | Surgical fastener applying apparatus |
US5766246A (en) | 1992-05-20 | 1998-06-16 | C. R. Bard, Inc. | Implantable prosthesis and method and apparatus for loading and delivering an implantable prothesis |
WO1995016221A1 (en) | 1992-06-12 | 1995-06-15 | Boit, Inc. | Liquid crystal color modulation displays |
US5263629A (en) | 1992-06-29 | 1993-11-23 | Ethicon, Inc. | Method and apparatus for achieving hemostasis along a staple line |
US5281197A (en) | 1992-07-27 | 1994-01-25 | Symbiosis Corporation | Endoscopic hemostatic agent delivery system |
US5330486A (en) | 1992-07-29 | 1994-07-19 | Wilk Peter J | Laparoscopic or endoscopic anastomosis technique and associated instruments |
US5514379A (en) | 1992-08-07 | 1996-05-07 | The General Hospital Corporation | Hydrogel compositions and methods of use |
CA2108605A1 (en) | 1992-10-21 | 1994-04-22 | Nagabhushanam Totakura | Bioabsorbable foam pledget |
US5468253A (en) | 1993-01-21 | 1995-11-21 | Ethicon, Inc. | Elastomeric medical device |
US5397324A (en) | 1993-03-10 | 1995-03-14 | Carroll; Brendan J. | Surgical stapler instrument and method for vascular hemostasis |
US5415334A (en) | 1993-05-05 | 1995-05-16 | Ethicon Endo-Surgery | Surgical stapler and staple cartridge |
GB9317490D0 (en) | 1993-08-23 | 1993-10-06 | Hercules Inc | Diaper barrier leg-cuff fabrics |
US5441193A (en) | 1993-09-23 | 1995-08-15 | United States Surgical Corporation | Surgical fastener applying apparatus with resilient film |
US5542594A (en) | 1993-10-06 | 1996-08-06 | United States Surgical Corporation | Surgical stapling apparatus with biocompatible surgical fabric |
CA2132917C (en) | 1993-10-07 | 2004-12-14 | John Charles Robertson | Circular anastomosis device |
CZ288792B6 (cs) | 1993-12-23 | 2001-09-12 | Johnson & Johnson Medical, Inc. | Bioabsorbovatelný chirurgický hemostat a způsob jeho výroby |
US5503638A (en) | 1994-02-10 | 1996-04-02 | Bio-Vascular, Inc. | Soft tissue stapling buttress |
US6704210B1 (en) | 1994-05-20 | 2004-03-09 | Medtronic, Inc. | Bioprothesis film strip for surgical stapler and method of attaching the same |
US5814057A (en) | 1994-06-03 | 1998-09-29 | Gunze Limited | Supporting element for staple region |
DE69531397T2 (de) | 1994-06-17 | 2004-04-22 | Heartport, Inc., Redwood City | Chirurgisches Klammerinstrument |
US5833695A (en) | 1994-07-13 | 1998-11-10 | Yoon; Inbae | Surgical stapling system and method of applying staples from multiple staple cartridges |
DE69419265T2 (de) | 1994-07-27 | 2000-01-05 | W.L. Gore & Associates, Inc. | Höchfeste poröse folie aus ptfe |
US6280453B1 (en) | 1994-09-29 | 2001-08-28 | Bard Asdi Inc. | Hernia mesh patch with stiffener line segment |
US6030392A (en) | 1995-01-18 | 2000-02-29 | Motorola, Inc. | Connector for hollow anatomical structures and methods of use |
JP3795100B2 (ja) | 1995-05-08 | 2006-07-12 | 株式会社伊垣医療設計 | 医療用縫合材 |
JP3526487B2 (ja) | 1995-05-08 | 2004-05-17 | 株式会社伊垣医療設計 | 医療用縫合材 |
US5895415A (en) | 1995-06-06 | 1999-04-20 | Optobionics Corporation | Multi-phasic microphotodiode retinal implant and adaptive imaging retinal stimulation system |
EP0861048A4 (en) * | 1995-07-03 | 2000-05-17 | Dirk A Frater | SYSTEM FOR FASTENING SUPPORT MATERIAL ON TISSUE CLASP DEVICES |
US6019791A (en) | 1995-07-17 | 2000-02-01 | Wood; Alfred E. | Buttress for cardiac valve reconstruction |
US5702409A (en) | 1995-07-21 | 1997-12-30 | W. L. Gore & Associates, Inc. | Device and method for reinforcing surgical staples |
US5810855A (en) * | 1995-07-21 | 1998-09-22 | Gore Enterprise Holdings, Inc. | Endoscopic device and method for reinforcing surgical staples |
US5782396A (en) | 1995-08-28 | 1998-07-21 | United States Surgical Corporation | Surgical stapler |
US6032849A (en) | 1995-08-28 | 2000-03-07 | United States Surgical | Surgical stapler |
US5762256A (en) | 1995-08-28 | 1998-06-09 | United States Surgical Corporation | Surgical stapler |
AU7398196A (en) | 1995-10-11 | 1997-04-30 | Fusion Medical Technologies, Inc. | Device and method for sealing tissue |
KR19990064208A (ko) | 1995-10-13 | 1999-07-26 | 트랜스바스큘라, 인코포레이티드 | 동맥 폐색부를 우회하고/거나 그 밖의 혈관 횡단 과정을 수행하기 위한 방법 및 장치 |
US5752974A (en) | 1995-12-18 | 1998-05-19 | Collagen Corporation | Injectable or implantable biomaterials for filling or blocking lumens and voids of the body |
JP4193917B2 (ja) | 1995-12-18 | 2008-12-10 | アンジオデバイス インターナショナル ゲーエムベーハー | 架橋ポリマー組成物およびその使用方法 |
US20020068949A1 (en) | 1996-02-23 | 2002-06-06 | Williamson Warren P. | Extremely long wire fasteners for use in minimally invasive surgery and means and method for handling those fasteners |
US6677258B2 (en) | 1996-05-29 | 2004-01-13 | E. I. Du Pont De Nemours And Company | Breathable composite sheet structure and absorbent articles utilizing same |
US7307031B2 (en) | 1997-05-29 | 2007-12-11 | The Procter & Gamble Company | Breathable composite sheet structure and absorbent articles utilizing same |
US6500777B1 (en) | 1996-06-28 | 2002-12-31 | Ethicon, Inc. | Bioresorbable oxidized cellulose composite material for prevention of postsurgical adhesions |
TW308613B (en) | 1996-08-19 | 1997-06-21 | Jyi-Shyang Wang | Manufacturing method and device for carbon fabric absorbent |
US7009034B2 (en) | 1996-09-23 | 2006-03-07 | Incept, Llc | Biocompatible crosslinked polymers |
US5752965A (en) | 1996-10-21 | 1998-05-19 | Bio-Vascular, Inc. | Apparatus and method for producing a reinforced surgical fastener suture line |
US5769892A (en) | 1996-10-22 | 1998-06-23 | Mitroflow International Inc. | Surgical stapler sleeve for reinforcing staple lines |
US5931847A (en) | 1997-01-09 | 1999-08-03 | Ethicon Endo-Surgery, Inc. | Surgical cutting instrument with improved cutting edge |
AU6444298A (en) | 1997-03-04 | 1998-09-22 | Medtronic, Inc. | Bioprothesis film strip for surgical stapler and method of attaching the same |
FR2762207B1 (fr) | 1997-04-17 | 1999-07-30 | Ethnor | Perfectionnements aux protheses sous-cutanees pour plastie mammaire |
US6120539A (en) | 1997-05-01 | 2000-09-19 | C. R. Bard Inc. | Prosthetic repair fabric |
US6433154B1 (en) | 1997-06-12 | 2002-08-13 | Bristol-Myers Squibb Company | Functional receptor/kinase chimera in yeast cells |
US5997895A (en) | 1997-09-16 | 1999-12-07 | Integra Lifesciences Corporation | Dural/meningeal repair product using collagen matrix |
US5865361A (en) | 1997-09-23 | 1999-02-02 | United States Surgical Corporation | Surgical stapling apparatus |
NL1007349C2 (nl) | 1997-10-24 | 1999-04-27 | Suyker Wilhelmus Joseph Leonardus | Systeem voor het mechanisch vervaardigen van anastomoses tussen holle structuren; alsmede inrichting en applicator voor gebruik daarbij. |
WO1999026826A2 (de) | 1997-11-14 | 1999-06-03 | Continental Teves Ag & Co. Ohg | Bremskraftübersetzungseinrichtung insbesondere für kraftfahrzeuge |
AU1923199A (en) | 1997-12-17 | 1999-07-05 | Hemodynamics, Inc. | Sealing media for surgery and wound closure |
US6007552A (en) | 1997-12-18 | 1999-12-28 | Minumys | Vascular clamps and surgical retractors with directional filaments for tissue engagement |
DE19757958A1 (de) | 1997-12-24 | 1999-07-01 | Lurgi Zimmer Ag | Verfahren zur Herstellung einer Cellulosecarbamatlösung |
US6099551A (en) * | 1998-03-12 | 2000-08-08 | Shelhigh, Inc. | Pericardial strip and stapler assembly for dividing and sealing visceral tissues and method of use thereof |
US6156677A (en) | 1998-03-25 | 2000-12-05 | Kimberly-Clark Worldwide, Inc. | Cellulose-Based medical packaging material sterilizable by oxidizing gas plasma |
US6517566B1 (en) | 1998-05-11 | 2003-02-11 | Surgical Connections, Inc. | Devices and methods for treating e.g. urinary stress incontinence |
US20050021085A1 (en) | 1998-05-11 | 2005-01-27 | Surgical Connections, Inc. | Surgical stabilizer devices and methods |
AU751697B2 (en) | 1998-05-11 | 2002-08-22 | Surgical Connections, Inc. | Devices and methods for treating e.g. urinary stress incontinence |
GB9810236D0 (en) | 1998-05-13 | 1998-07-08 | Microbiological Res Authority | Improvements relating to encapsulation of bioactive agents |
US6669735B1 (en) | 1998-07-31 | 2003-12-30 | Davol, Inc. | Prosthesis for surgical treatment of hernia |
US6593884B1 (en) | 1998-08-02 | 2003-07-15 | Super Dimension Ltd. | Intrabody navigation system for medical applications |
US6818018B1 (en) | 1998-08-14 | 2004-11-16 | Incept Llc | In situ polymerizable hydrogels |
US6605294B2 (en) | 1998-08-14 | 2003-08-12 | Incept Llc | Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels |
EP1104324B8 (en) | 1998-08-14 | 2011-06-22 | Incept Llc | Apparatus for in situ formation of hydrogels |
US6179862B1 (en) | 1998-08-14 | 2001-01-30 | Incept Llc | Methods and apparatus for in situ formation of hydrogels |
US6152943A (en) | 1998-08-14 | 2000-11-28 | Incept Llc | Methods and apparatus for intraluminal deposition of hydrogels |
US7347850B2 (en) | 1998-08-14 | 2008-03-25 | Incept Llc | Adhesion barriers applicable by minimally invasive surgery and methods of use thereof |
US6703047B2 (en) | 2001-02-02 | 2004-03-09 | Incept Llc | Dehydrated hydrogel precursor-based, tissue adherent compositions and methods of use |
US6514534B1 (en) | 1998-08-14 | 2003-02-04 | Incept Llc | Methods for forming regional tissue adherent barriers and drug delivery systems |
DE19836950B4 (de) | 1998-08-17 | 2004-09-02 | Deutsches Zentrum für Luft- und Raumfahrt e.V. | Chirurgisches Instrument in Form eines Nahtklammergerätes |
JP2002526188A (ja) | 1998-09-24 | 2002-08-20 | スーパー ディメンション リミテッド | 体内への医療処置中にカテーテルの位置を判定するためのシステム及び方法 |
US7662409B2 (en) | 1998-09-25 | 2010-02-16 | Gel-Del Technologies, Inc. | Protein matrix materials, devices and methods of making and using thereof |
US6299631B1 (en) | 1998-11-12 | 2001-10-09 | Poly-Med, Inc. | Polyester/cyanoacrylate tissue adhesive formulations |
US6142933A (en) | 1998-11-23 | 2000-11-07 | Ethicon Endo-Surgery, Inc. | Anoscope for hemorrhoidal surgery |
JP2002531217A (ja) | 1998-12-04 | 2002-09-24 | チャンドラシェカー ピー. パサック, | 生体適合性架橋ポリマー |
JP3531000B2 (ja) | 1998-12-07 | 2004-05-24 | グンゼ株式会社 | 吻合補綴材 |
US6312457B1 (en) | 1999-04-01 | 2001-11-06 | Boston Scientific Corporation | Intraluminal lining |
AU5003100A (en) | 1999-05-11 | 2000-11-21 | Craig Berky | Surgical clamp devices and methods especially useful in cardiac surgery |
US6723428B1 (en) | 1999-05-27 | 2004-04-20 | Foss Manufacturing Co., Inc. | Anti-microbial fiber and fibrous products |
DE19924311A1 (de) | 1999-05-27 | 2000-11-30 | Walter A Rau | Klammerschneidegerät und Zusatzvorrichtung für ein solches |
US8025199B2 (en) | 2004-02-23 | 2011-09-27 | Tyco Healthcare Group Lp | Surgical cutting and stapling device |
US6325810B1 (en) | 1999-06-30 | 2001-12-04 | Ethicon, Inc. | Foam buttress for stapling apparatus |
US6927315B1 (en) | 1999-07-30 | 2005-08-09 | 3M Innovative Properties Company | Adhesive composite having distinct phases |
US6080169A (en) | 1999-08-10 | 2000-06-27 | Turtel; Lawrence | Strabismus recession clamp |
US6702828B2 (en) | 1999-09-01 | 2004-03-09 | Converge Medical, Inc. | Anastomosis system |
US6312474B1 (en) | 1999-09-15 | 2001-11-06 | Bio-Vascular, Inc. | Resorbable implant materials |
US6627749B1 (en) | 1999-11-12 | 2003-09-30 | University Of Iowa Research Foundation | Powdered oxidized cellulose |
US6302897B1 (en) | 1999-11-19 | 2001-10-16 | Ethicon, Inc. | Device for deploying medical textiles |
US6436030B2 (en) | 2000-01-31 | 2002-08-20 | Om P. Rehil | Hiatal hernia repair patch and method for using the same |
US6273897B1 (en) | 2000-02-29 | 2001-08-14 | Ethicon, Inc. | Surgical bettress and surgical stapling apparatus |
US6656200B2 (en) | 2000-04-07 | 2003-12-02 | Collagen Matrix, Inc. | Embolization device |
US7232449B2 (en) | 2000-04-29 | 2007-06-19 | Medtronic, Inc. | Components, systems and methods for forming anastomoses using magnetism or other coupling means |
US7241300B2 (en) | 2000-04-29 | 2007-07-10 | Medtronic, Inc, | Components, systems and methods for forming anastomoses using magnetism or other coupling means |
AU782756B2 (en) | 2000-05-12 | 2005-08-25 | Systagenix Wound Management Ip Co. B.V. | Solid composition exhibiting selective binding to dissolved iron |
CA2409093C (en) | 2000-05-16 | 2009-07-21 | Regents Of The University Of Minnesota | High mass throughput particle generation using multiple nozzle spraying |
US6896684B2 (en) | 2000-06-12 | 2005-05-24 | Niti Medical Technologies Ltd. | Surgical clip applicator device |
US6610006B1 (en) | 2000-07-25 | 2003-08-26 | C. R. Bard, Inc. | Implantable prosthesis |
WO2002009594A2 (en) | 2000-07-31 | 2002-02-07 | Sumit Roy | Device, apparatus, and prosthesis for suturless anastomosis |
US6746458B1 (en) | 2000-09-07 | 2004-06-08 | William G. Cloud | Mesh material to repair hernias |
US7334717B2 (en) | 2001-10-05 | 2008-02-26 | Tyco Healthcare Group Lp | Surgical fastener applying apparatus |
US7909837B2 (en) | 2000-12-13 | 2011-03-22 | Medtronic, Inc. | Methods, devices and systems for forming magnetic anastomoses |
JP2002202213A (ja) | 2000-12-28 | 2002-07-19 | Yaskawa Electric Corp | 締め付け圧力検出方法 |
US7595392B2 (en) | 2000-12-29 | 2009-09-29 | University Of Iowa Research Foundation | Biodegradable oxidized cellulose esters |
US20020091397A1 (en) | 2001-01-05 | 2002-07-11 | Te-Chuan Chen | Structure of intestinal anastomosis gun |
US6568398B2 (en) | 2001-03-07 | 2003-05-27 | Edgar C. Cohen | Method for hemostasis |
DE60239188D1 (de) | 2001-03-09 | 2011-03-31 | Boston Scient Ltd | System zum einsetzen einer schlinge |
US8033983B2 (en) | 2001-03-09 | 2011-10-11 | Boston Scientific Scimed, Inc. | Medical implant |
US6551356B2 (en) | 2001-03-19 | 2003-04-22 | Ethicon, Inc. | Pocketed hernia repair |
GB0108088D0 (en) | 2001-03-30 | 2001-05-23 | Browning Healthcare Ltd | Surgical implant |
US6638285B2 (en) | 2001-04-16 | 2003-10-28 | Shlomo Gabbay | Biological tissue strip and system and method to seal tissue |
FI20010898A0 (fi) | 2001-04-30 | 2001-04-30 | Ylae Herttuala Seppo | Ekstrasellulaarinen superoksididismutaasi (EC-SOD) geeniterapia restenoosoin ehkäisemiseksi |
US6503257B2 (en) * | 2001-05-07 | 2003-01-07 | Ethicon Endo-Surgery, Inc. | Method for releasing buttress material attached to a surgical fastening device |
US7247338B2 (en) | 2001-05-16 | 2007-07-24 | Regents Of The University Of Minnesota | Coating medical devices |
US20030181927A1 (en) | 2001-06-21 | 2003-09-25 | Wallace Michael P. | Aneurysm neck obstruction device |
US6454780B1 (en) | 2001-06-21 | 2002-09-24 | Scimed Life Systems, Inc. | Aneurysm neck obstruction device |
US6726706B2 (en) | 2001-06-26 | 2004-04-27 | Steven Dominguez | Suture tape and method for use |
US7108701B2 (en) | 2001-09-28 | 2006-09-19 | Ethicon, Inc. | Drug releasing anastomosis devices and methods for treating anastomotic sites |
US20030065345A1 (en) | 2001-09-28 | 2003-04-03 | Kevin Weadock | Anastomosis devices and methods for treating anastomotic sites |
US7892247B2 (en) | 2001-10-03 | 2011-02-22 | Bioconnect Systems, Inc. | Devices and methods for interconnecting vessels |
US7087065B2 (en) | 2001-10-04 | 2006-08-08 | Ethicon, Inc. | Mesh for pelvic floor repair |
DE10155490A1 (de) | 2001-11-13 | 2003-05-22 | Zf Lemfoerder Metallwaren Ag | Kraftverbindungsstrebe |
US7649089B2 (en) | 2001-12-06 | 2010-01-19 | University Of Iowa Research Foundation | Biodegradable oxidized cellulose esters and their uses as microspheres |
US6939358B2 (en) | 2001-12-20 | 2005-09-06 | Gore Enterprise Holdings, Inc. | Apparatus and method for applying reinforcement material to a surgical stapler |
US20030125676A1 (en) | 2001-12-28 | 2003-07-03 | Becton, Dickinson And Company | Medical needle assemblies |
US6790213B2 (en) | 2002-01-07 | 2004-09-14 | C.R. Bard, Inc. | Implantable prosthesis |
US7128748B2 (en) | 2002-03-26 | 2006-10-31 | Synovis Life Technologies, Inc. | Circular stapler buttress combination |
EP1494601B1 (en) | 2002-04-15 | 2012-01-11 | Tyco Healthcare Group LP | Instrument introducer |
AU2003230933B2 (en) | 2002-04-15 | 2008-01-10 | Cook Biotech Incorporated | Apparatus and method for producing a reinforced surgical staple line |
EP2298187B1 (en) | 2002-04-16 | 2017-06-07 | Covidien LP | Surgical stapler and method |
US6843252B2 (en) | 2002-04-23 | 2005-01-18 | Samuel W. Harrison | Surgical drape |
US7141055B2 (en) | 2002-04-24 | 2006-11-28 | Surgical Connections, Inc. | Resection and anastomosis devices and methods |
US7207471B2 (en) * | 2002-05-10 | 2007-04-24 | Tyco Healthcare Group Lp | Electrosurgical stapling apparatus |
US6736823B2 (en) | 2002-05-10 | 2004-05-18 | C.R. Bard, Inc. | Prosthetic repair fabric |
US6736854B2 (en) | 2002-05-10 | 2004-05-18 | C. R. Bard, Inc. | Prosthetic repair fabric with erosion resistant edge |
CA2485107C (en) | 2002-05-10 | 2011-07-12 | Tyco Healthcare Group Lp | Surgical stapling apparatus having a wound closure material applicator assembly |
DE60307637T2 (de) | 2002-06-17 | 2007-08-09 | Tyco Healthcare Group Lp, Norwalk | Ringförmige halterungsstruktur |
JP3680050B2 (ja) | 2002-09-18 | 2005-08-10 | 株式会社東芝 | 医療用マニピュレータ及びその制御方法 |
ES2377813T5 (es) | 2002-10-04 | 2020-12-18 | Covidien Lp | Conjunto de herramienta para un dispositivo de grapado quirúrgico |
US7799026B2 (en) | 2002-11-14 | 2010-09-21 | Covidien Ag | Compressible jaw configuration with bipolar RF output electrodes for soft tissue fusion |
DE10310995B3 (de) | 2003-03-06 | 2004-09-16 | Aesculap Ag & Co. Kg | Verschlußvorrichtung für einen Stichkanal und Applikatorvorrichtung |
US6982013B1 (en) | 2003-03-17 | 2006-01-03 | The United States Of America As Represented By The Secretary Of The Navy | Electrostatic charge dissipation compositions including energetic particles |
WO2004091377A2 (en) | 2003-03-28 | 2004-10-28 | Downey Earl C | Surgical instrument with trigger control |
US7160299B2 (en) | 2003-05-01 | 2007-01-09 | Sherwood Services Ag | Method of fusing biomaterials with radiofrequency energy |
US20040254590A1 (en) | 2003-06-16 | 2004-12-16 | Hoffman Gary H. | Method and instrument for the performance of stapled anastamoses |
US20040260315A1 (en) | 2003-06-17 | 2004-12-23 | Dell Jeffrey R. | Expandable tissue support member and method of forming the support member |
CN1309886C (zh) | 2003-06-30 | 2007-04-11 | 株式会社晓星 | 溶于n-甲基吗啉-n-氧化物的纤维素溶液及使用该溶液的纤维素纤维的制造方法 |
US6964363B2 (en) | 2003-07-09 | 2005-11-15 | Ethicon Endo-Surgery, Inc. | Surgical stapling instrument having articulation joint support plates for supporting a firing bar |
CA2531909C (en) | 2003-07-16 | 2011-02-15 | Tyco Healthcare Group Lp | Surgical stapling device with tissue tensioner |
DE602004029366D1 (de) | 2003-07-17 | 2010-11-11 | Gunze Kk | Nahtverstärkungsmaterial für ein automatisches nähgerät |
US7547312B2 (en) | 2003-09-17 | 2009-06-16 | Gore Enterprise Holdings, Inc. | Circular stapler buttress |
US20050059997A1 (en) | 2003-09-17 | 2005-03-17 | Bauman Ann M. | Circular stapler buttress |
US20050070929A1 (en) | 2003-09-30 | 2005-03-31 | Dalessandro David A. | Apparatus and method for attaching a surgical buttress to a stapling apparatus |
US10105140B2 (en) | 2009-11-20 | 2018-10-23 | Covidien Lp | Surgical console and hand-held surgical device |
US20050118435A1 (en) | 2003-12-01 | 2005-06-02 | Kimberly-Clark Worldwide, Inc. | Films and methods of forming films having polyorganosiloxane enriched surface layers |
US20050149073A1 (en) | 2003-12-17 | 2005-07-07 | Arani Djavad T. | Mechanisms and methods used in the anastomosis of biological conduits |
US20050283256A1 (en) | 2004-02-09 | 2005-12-22 | Codman & Shurtleff, Inc. | Collagen device and method of preparing the same |
WO2005079675A2 (en) | 2004-02-17 | 2005-09-01 | Cook Biotech Incorporated | Medical devices and methods for applying bolster material |
JP2008505680A (ja) | 2004-07-08 | 2008-02-28 | オールトレイセル・ディベロップメント・サービシズ・リミテッド | 皮膚の創傷の出血を制御するための送達システム |
US7229690B2 (en) | 2004-07-26 | 2007-06-12 | Massachusetts Institute Of Technology | Microspheres including nanoparticles |
US7147138B2 (en) * | 2004-07-28 | 2006-12-12 | Ethicon Endo-Surgery, Inc. | Surgical stapling instrument having an electroactive polymer actuated buttress deployment mechanism |
FR2873700B1 (fr) | 2004-07-29 | 2006-11-24 | Centre Nat Rech Scient Cnrse | Procede d'oxydation controlee de polysaccharides |
US7645874B2 (en) | 2004-08-05 | 2010-01-12 | Xylos Corporation | Cellulose oxidation by nitrogen dioxide in a perfluorinated tertiary amine solvent |
EP1791473A4 (en) | 2004-08-17 | 2011-09-14 | Tyco Healthcare | STACK SUPPORT STRUCTURES |
US7210810B1 (en) | 2004-09-03 | 2007-05-01 | Pmt Corporation | Surgical headlight assembly |
US8372094B2 (en) | 2004-10-15 | 2013-02-12 | Covidien Lp | Seal element for anastomosis |
WO2006044490A2 (en) | 2004-10-18 | 2006-04-27 | Tyco Healthcare Group, Lp | Annular adhesive structure |
US7717313B2 (en) | 2004-10-18 | 2010-05-18 | Tyco Healthcare Group Lp | Surgical apparatus and structure for applying sprayable wound treatment material |
US7845536B2 (en) | 2004-10-18 | 2010-12-07 | Tyco Healthcare Group Lp | Annular adhesive structure |
US7938307B2 (en) | 2004-10-18 | 2011-05-10 | Tyco Healthcare Group Lp | Support structures and methods of using the same |
EP1845870A1 (en) | 2004-11-18 | 2007-10-24 | 3M Innovative Properties Company | Non-skin-contacting microneedle array applicator |
DE102004058119A1 (de) | 2004-12-02 | 2006-06-08 | Daimlerchrysler Ag | Poröse SiC-Körper mit Mikrokanälen und Verfahren zu deren Herstellung |
US7328829B2 (en) | 2004-12-13 | 2008-02-12 | Niti Medical Technologies Ltd. | Palm size surgical stapler for single hand operation |
US20060173470A1 (en) | 2005-01-31 | 2006-08-03 | Oray B N | Surgical fastener buttress material |
US7611494B2 (en) | 2005-02-08 | 2009-11-03 | Confluent Surgical, Inc. | Spray for fluent materials |
US20070203510A1 (en) | 2006-02-28 | 2007-08-30 | Bettuchi Michael J | Annular disk for reduction of anastomotic tension and methods of using the same |
US9364229B2 (en) | 2005-03-15 | 2016-06-14 | Covidien Lp | Circular anastomosis structures |
US7942890B2 (en) | 2005-03-15 | 2011-05-17 | Tyco Healthcare Group Lp | Anastomosis composite gasket |
FR2884134B1 (fr) | 2005-04-07 | 2008-03-28 | Safradim Production Soc Par Ac | Systeme de mise en place de moyens formant renfort d'une suture |
DE102005017733A1 (de) | 2005-04-15 | 2006-10-19 | Basf Ag | Löslichkeit von Cellulose in ionischen Flüssigkeiten unter Zugabe von Aminbase |
US20100016888A1 (en) | 2005-05-05 | 2010-01-21 | Allison Calabrese | Surgical Gasket |
US7655288B2 (en) | 2005-07-29 | 2010-02-02 | Gore Enterprise Holdings, Inc. | Composite self-cohered web materials |
US7559937B2 (en) | 2005-08-09 | 2009-07-14 | Towertech Research Group | Surgical fastener apparatus and reinforcing material |
US7669746B2 (en) | 2005-08-31 | 2010-03-02 | Ethicon Endo-Surgery, Inc. | Staple cartridges for forming staples having differing formed staple heights |
US7641091B2 (en) | 2005-10-04 | 2010-01-05 | Tyco Healthcare Group Lp | Staple drive assembly |
JP4707533B2 (ja) | 2005-10-27 | 2011-06-22 | 太陽誘電株式会社 | 圧電薄膜共振器およびフィルタ |
US7896895B2 (en) * | 2005-11-23 | 2011-03-01 | Ethicon Endo-Surgery, Inc. | Surgical clip and applier device and method of use |
US9687262B2 (en) | 2005-11-30 | 2017-06-27 | CARDINAL HEALTH SWITZERLAND 515 GmbH | Methods and devices for treating vulnerable plaque |
US7464849B2 (en) | 2006-01-31 | 2008-12-16 | Ethicon Endo-Surgery, Inc. | Electro-mechanical surgical instrument with closure system and anvil alignment components |
US9629626B2 (en) | 2006-02-02 | 2017-04-25 | Covidien Lp | Mechanically tuned buttress material to assist with proper formation of surgical element in diseased tissue |
KR20080102152A (ko) | 2006-02-03 | 2008-11-24 | 티슈메드 리미티드 | 조직-접착 물질 |
US7793813B2 (en) | 2006-02-28 | 2010-09-14 | Tyco Healthcare Group Lp | Hub for positioning annular structure on a surgical device |
US7709631B2 (en) | 2006-03-13 | 2010-05-04 | Xylos Corporation | Oxidized microbial cellulose and use thereof |
US8062673B2 (en) | 2006-04-11 | 2011-11-22 | E I Du Pont De Nemours And Company | Process for embolization using swellable and deformable microspheres |
US8252339B2 (en) | 2006-04-11 | 2012-08-28 | Massachusetts Institute Of Technology | Medical treatment applications of swellable and deformable microspheres |
US20070243227A1 (en) | 2006-04-14 | 2007-10-18 | Michael Gertner | Coatings for surgical staplers |
US8367089B2 (en) | 2006-04-24 | 2013-02-05 | Axcelon Biopolymers Corporation | Nanosilver coated bacterial cellulose |
US20070246505A1 (en) * | 2006-04-24 | 2007-10-25 | Medical Ventures Inc. | Surgical buttress assemblies and methods of uses thereof |
US7790273B2 (en) | 2006-05-24 | 2010-09-07 | Nellix, Inc. | Material for creating multi-layered films and methods for making the same |
US20080029570A1 (en) | 2006-08-02 | 2008-02-07 | Shelton Frederick E | Pneumatically powered surgical cutting and fastening instrument with improved volume storage |
US8220690B2 (en) | 2006-09-29 | 2012-07-17 | Ethicon Endo-Surgery, Inc. | Connected surgical staples and stapling instruments for deploying the same |
EP2073719B1 (en) | 2006-10-26 | 2017-05-03 | Covidien LP | Device using shape memory alloys for buttress attachment |
US7845533B2 (en) | 2007-06-22 | 2010-12-07 | Tyco Healthcare Group Lp | Detachable buttress material retention systems for use with a surgical stapling device |
BRPI0622109A2 (pt) | 2006-11-02 | 2013-10-29 | Sca Hygiene Prod Ab | Dispositivo de transferência |
US7708180B2 (en) | 2006-11-09 | 2010-05-04 | Ethicon Endo-Surgery, Inc. | Surgical fastening device with initiator impregnation of a matrix or buttress to improve adhesive application |
US8177798B2 (en) | 2006-12-05 | 2012-05-15 | Tyco Healthcare Group Lp | Adhesive coated stent and insertion instrument |
US7434717B2 (en) | 2007-01-11 | 2008-10-14 | Ethicon Endo-Surgery, Inc. | Apparatus for closing a curved anvil of a surgical stapling device |
US20080169328A1 (en) | 2007-01-11 | 2008-07-17 | Shelton Frederick E | Buttress material for use with a surgical stapler |
US20080220047A1 (en) | 2007-03-05 | 2008-09-11 | Sawhney Amarpreet S | Low-swelling biocompatible hydrogels |
US9888924B2 (en) | 2007-03-06 | 2018-02-13 | Covidien Lp | Wound closure material |
US8011555B2 (en) * | 2007-03-06 | 2011-09-06 | Tyco Healthcare Group Lp | Surgical stapling apparatus |
US8011550B2 (en) | 2009-03-31 | 2011-09-06 | Tyco Healthcare Group Lp | Surgical stapling apparatus |
US8413871B2 (en) | 2007-03-06 | 2013-04-09 | Covidien Lp | Surgical stapling apparatus |
US20080216855A1 (en) | 2007-03-07 | 2008-09-11 | Nasca Brian R | Exfoliating apparatus |
US7604151B2 (en) | 2007-03-15 | 2009-10-20 | Ethicon Endo-Surgery, Inc. | Surgical stapling systems and staple cartridges for deploying surgical staples with tissue compression features |
US8038045B2 (en) | 2007-05-25 | 2011-10-18 | Tyco Healthcare Group Lp | Staple buttress retention system |
JP5474779B2 (ja) | 2007-06-12 | 2014-04-16 | コンバテック・テクノロジーズ・インコーポレイテッド | オストミー用装置 |
US7950561B2 (en) | 2007-06-18 | 2011-05-31 | Tyco Healthcare Group Lp | Structure for attachment of buttress material to anvils and cartridges of surgical staplers |
US7665646B2 (en) | 2007-06-18 | 2010-02-23 | Tyco Healthcare Group Lp | Interlocking buttress material retention system |
WO2009001697A2 (en) | 2007-06-25 | 2008-12-31 | Otsuka Pharmaceutical Co., Ltd. | Microspheres having core/shell structure |
US8062330B2 (en) | 2007-06-27 | 2011-11-22 | Tyco Healthcare Group Lp | Buttress and surgical stapling apparatus |
JP5042738B2 (ja) | 2007-07-30 | 2012-10-03 | テルモ株式会社 | 医療用マニピュレータの作業機構及び洗浄方法 |
US8470360B2 (en) | 2008-04-18 | 2013-06-25 | Warsaw Orthopedic, Inc. | Drug depots having different release profiles for reducing, preventing or treating pain and inflammation |
US8317790B2 (en) | 2007-09-14 | 2012-11-27 | W. L. Gore & Associates, Inc. | Surgical staple line reinforcements |
US8678263B2 (en) | 2007-09-24 | 2014-03-25 | Covidien Lp | Materials delivery system for stapling device |
AU2008311321B2 (en) | 2007-10-08 | 2012-11-08 | W. L. Gore & Associates, Inc. | Apparatus for supplying surgical staple line reinforcement |
US20090206125A1 (en) * | 2008-02-15 | 2009-08-20 | Ethicon Endo-Surgery, Inc. | Packaging for attaching buttress material to a surgical stapling instrument |
US9770245B2 (en) | 2008-02-15 | 2017-09-26 | Ethicon Llc | Layer arrangements for surgical staple cartridges |
US8033483B2 (en) | 2008-04-25 | 2011-10-11 | Confluent Surgical Inc. | Silicone spray tip |
US8408480B2 (en) | 2008-04-25 | 2013-04-02 | Confluent Surgical, Inc. | Self-cleaning spray tip |
US8091756B2 (en) | 2008-05-09 | 2012-01-10 | Tyco Healthcare Group Lp | Varying tissue compression using take-up component |
GB2471815A (en) | 2008-05-21 | 2011-01-12 | Cook Biotech Inc | Devices and methods for applying bolster materials to surgical fastening apparatus |
US9295757B2 (en) | 2008-06-10 | 2016-03-29 | Cook Biotech Incorporated | Quilted implantable graft |
US8834465B2 (en) | 2008-07-15 | 2014-09-16 | Immersion Corporation | Modular tool with signal feedback |
US8409223B2 (en) | 2008-08-29 | 2013-04-02 | Covidien Lp | Endoscopic surgical clip applier with clip retention |
US8181838B2 (en) | 2008-09-10 | 2012-05-22 | Tyco Healthcare Group Lp | Surgical stapling device |
US8210453B2 (en) | 2008-09-12 | 2012-07-03 | Confluent Surgical, Inc. | Spray applicator |
US7886951B2 (en) | 2008-11-24 | 2011-02-15 | Tyco Healthcare Group Lp | Pouch used to deliver medication when ruptured |
EP2395982B1 (en) | 2008-12-23 | 2014-10-22 | Surmodics Pharmaceuticals, Inc. | An implantable composite comprising a tacky biocompatible polymer film and a releasable bioactive agent |
US8317071B1 (en) * | 2009-03-09 | 2012-11-27 | Cardica, Inc. | Endocutter with auto-feed buttress |
US7967179B2 (en) | 2009-03-31 | 2011-06-28 | Tyco Healthcare Group Lp | Center cinch and release of buttress material |
US8016178B2 (en) | 2009-03-31 | 2011-09-13 | Tyco Healthcare Group Lp | Surgical stapling apparatus |
US7988027B2 (en) | 2009-03-31 | 2011-08-02 | Tyco Healthcare Group Lp | Crimp and release of suture holding buttress material |
US8365972B2 (en) | 2009-03-31 | 2013-02-05 | Covidien Lp | Surgical stapling apparatus |
US9486215B2 (en) | 2009-03-31 | 2016-11-08 | Covidien Lp | Surgical stapling apparatus |
US8348126B2 (en) * | 2009-03-31 | 2013-01-08 | Covidien Lp | Crimp and release of suture holding buttress material |
US8418909B2 (en) | 2009-06-02 | 2013-04-16 | Covidien Lp | Surgical instrument and method for performing a resection |
JP5562583B2 (ja) | 2009-06-24 | 2014-07-30 | カール シュトルツ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディートゲゼルシャフト | 医療用ロボットシステム |
JP2012531240A (ja) | 2009-06-26 | 2012-12-10 | クイックリング メディカル テクノロジーズ リミテッド | 外科用ステープラーおよび外科用ステープリングの方法 |
US9463260B2 (en) | 2009-06-29 | 2016-10-11 | Covidien Lp | Self-sealing compositions |
US10383629B2 (en) | 2009-08-10 | 2019-08-20 | Covidien Lp | System and method for preventing reprocessing of a powered surgical instrument |
AU2010303552B2 (en) | 2009-10-06 | 2013-11-14 | Regents Of The University Of Minnesota | Bioresorbable embolization microspheres |
US9610080B2 (en) | 2009-10-15 | 2017-04-04 | Covidien Lp | Staple line reinforcement for anvil and cartridge |
US9693772B2 (en) | 2009-10-15 | 2017-07-04 | Covidien Lp | Staple line reinforcement for anvil and cartridge |
US10842485B2 (en) * | 2009-10-15 | 2020-11-24 | Covidien Lp | Brachytherapy buttress |
US20150231409A1 (en) * | 2009-10-15 | 2015-08-20 | Covidien Lp | Buttress brachytherapy and integrated staple line markers for margin identification |
US8157151B2 (en) | 2009-10-15 | 2012-04-17 | Tyco Healthcare Group Lp | Staple line reinforcement for anvil and cartridge |
US8322590B2 (en) | 2009-10-28 | 2012-12-04 | Covidien Lp | Surgical stapling instrument |
US8464925B2 (en) | 2010-05-11 | 2013-06-18 | Ethicon Endo-Surgery, Inc. | Methods and apparatus for delivering tissue treatment compositions to stapled tissue |
US8646674B2 (en) | 2010-05-11 | 2014-02-11 | Ethicon Endo-Surgery, Inc. | Methods and apparatus for delivering tissue treatment compositions to stapled tissue |
US20110293690A1 (en) | 2010-05-27 | 2011-12-01 | Tyco Healthcare Group Lp | Biodegradable Polymer Encapsulated Microsphere Particulate Film and Method of Making Thereof |
JP5033222B2 (ja) | 2010-06-04 | 2012-09-26 | 株式会社アワジテック | 腕ホルダー |
US9168038B2 (en) | 2010-09-30 | 2015-10-27 | Ethicon Endo-Surgery, Inc. | Staple cartridge comprising a tissue thickness compensator |
US8740034B2 (en) | 2010-09-30 | 2014-06-03 | Ethicon Endo-Surgery, Inc. | Surgical stapling instrument with interchangeable staple cartridge arrangements |
US9204880B2 (en) | 2012-03-28 | 2015-12-08 | Ethicon Endo-Surgery, Inc. | Tissue thickness compensator comprising capsules defining a low pressure environment |
US10213198B2 (en) * | 2010-09-30 | 2019-02-26 | Ethicon Llc | Actuator for releasing a tissue thickness compensator from a fastener cartridge |
US9277919B2 (en) | 2010-09-30 | 2016-03-08 | Ethicon Endo-Surgery, Llc | Tissue thickness compensator comprising fibers to produce a resilient load |
US9320523B2 (en) * | 2012-03-28 | 2016-04-26 | Ethicon Endo-Surgery, Llc | Tissue thickness compensator comprising tissue ingrowth features |
US9517164B2 (en) | 2010-09-30 | 2016-12-13 | Covidien Lp | Wound dressing with advanced fluid handling |
US9839420B2 (en) * | 2010-09-30 | 2017-12-12 | Ethicon Llc | Tissue thickness compensator comprising at least one medicament |
US9332974B2 (en) | 2010-09-30 | 2016-05-10 | Ethicon Endo-Surgery, Llc | Layered tissue thickness compensator |
US8348130B2 (en) | 2010-12-10 | 2013-01-08 | Covidien Lp | Surgical apparatus including surgical buttress |
US8518440B2 (en) | 2010-12-21 | 2013-08-27 | Confluent Surgical, Inc. | Biodegradable osmotic pump implant for drug delivery |
US9084602B2 (en) | 2011-01-26 | 2015-07-21 | Covidien Lp | Buttress film with hemostatic action for surgical stapling apparatus |
IT1405423B1 (it) | 2011-02-25 | 2014-01-10 | Thd Spa | Dispositivo per impiantare una protesi in un tessuto |
US8479968B2 (en) | 2011-03-10 | 2013-07-09 | Covidien Lp | Surgical instrument buttress attachment |
US8540131B2 (en) | 2011-03-15 | 2013-09-24 | Ethicon Endo-Surgery, Inc. | Surgical staple cartridges with tissue tethers for manipulating divided tissue and methods of using same |
US8579990B2 (en) | 2011-03-30 | 2013-11-12 | Ethicon, Inc. | Tissue repair devices of rapid therapeutic absorbency |
US8789737B2 (en) | 2011-04-27 | 2014-07-29 | Covidien Lp | Circular stapler and staple line reinforcement material |
US9492170B2 (en) | 2011-08-10 | 2016-11-15 | Ethicon Endo-Surgery, Inc. | Device for applying adjunct in endoscopic procedure |
US9999408B2 (en) * | 2011-09-14 | 2018-06-19 | Ethicon Endo-Surgery, Inc. | Surgical instrument with fluid fillable buttress |
US9016539B2 (en) | 2011-10-25 | 2015-04-28 | Covidien Lp | Multi-use loading unit |
US9675351B2 (en) | 2011-10-26 | 2017-06-13 | Covidien Lp | Buttress release from surgical stapler by knife pushing |
US8584920B2 (en) | 2011-11-04 | 2013-11-19 | Covidien Lp | Surgical stapling apparatus including releasable buttress |
US9351732B2 (en) | 2011-12-14 | 2016-05-31 | Covidien Lp | Buttress attachment to degradable polymer zones |
US9351731B2 (en) | 2011-12-14 | 2016-05-31 | Covidien Lp | Surgical stapling apparatus including releasable surgical buttress |
US8967448B2 (en) | 2011-12-14 | 2015-03-03 | Covidien Lp | Surgical stapling apparatus including buttress attachment via tabs |
US9113885B2 (en) | 2011-12-14 | 2015-08-25 | Covidien Lp | Buttress assembly for use with surgical stapling device |
US9237892B2 (en) * | 2011-12-14 | 2016-01-19 | Covidien Lp | Buttress attachment to the cartridge surface |
US9010608B2 (en) | 2011-12-14 | 2015-04-21 | Covidien Lp | Releasable buttress retention on a surgical stapler |
JP5913631B2 (ja) | 2011-12-31 | 2016-05-11 | ベイジーン リミテッド | Parp阻害剤としての縮合四環式または縮合五環式ピリドフタラジノン |
US9010612B2 (en) | 2012-01-26 | 2015-04-21 | Covidien Lp | Buttress support design for EEA anvil |
US9010609B2 (en) | 2012-01-26 | 2015-04-21 | Covidien Lp | Circular stapler including buttress |
US9326773B2 (en) | 2012-01-26 | 2016-05-03 | Covidien Lp | Surgical device including buttress material |
US9931116B2 (en) | 2012-02-10 | 2018-04-03 | Covidien Lp | Buttress composition |
US8820606B2 (en) | 2012-02-24 | 2014-09-02 | Covidien Lp | Buttress retention system for linear endostaplers |
RU2644272C2 (ru) * | 2012-03-28 | 2018-02-08 | Этикон Эндо-Серджери, Инк. | Узел ограничения, включающий компенсатор толщины ткани |
US9198662B2 (en) * | 2012-03-28 | 2015-12-01 | Ethicon Endo-Surgery, Inc. | Tissue thickness compensator having improved visibility |
US20140048580A1 (en) * | 2012-08-20 | 2014-02-20 | Covidien Lp | Buttress attachment features for surgical stapling apparatus |
US9161753B2 (en) | 2012-10-10 | 2015-10-20 | Covidien Lp | Buttress fixation for a circular stapler |
US9192384B2 (en) | 2012-11-09 | 2015-11-24 | Covidien Lp | Recessed groove for better suture retention |
US20140131418A1 (en) | 2012-11-09 | 2014-05-15 | Covidien Lp | Surgical Stapling Apparatus Including Buttress Attachment |
US9295466B2 (en) | 2012-11-30 | 2016-03-29 | Covidien Lp | Surgical apparatus including surgical buttress |
US9681936B2 (en) | 2012-11-30 | 2017-06-20 | Covidien Lp | Multi-layer porous film material |
US9402627B2 (en) | 2012-12-13 | 2016-08-02 | Covidien Lp | Folded buttress for use with a surgical apparatus |
US9204881B2 (en) | 2013-01-11 | 2015-12-08 | Covidien Lp | Buttress retainer for EEA anvil |
US9433420B2 (en) | 2013-01-23 | 2016-09-06 | Covidien Lp | Surgical apparatus including surgical buttress |
US9192383B2 (en) | 2013-02-04 | 2015-11-24 | Covidien Lp | Circular stapling device including buttress material |
US9414839B2 (en) | 2013-02-04 | 2016-08-16 | Covidien Lp | Buttress attachment for circular stapling device |
US9386984B2 (en) * | 2013-02-08 | 2016-07-12 | Ethicon Endo-Surgery, Llc | Staple cartridge comprising a releasable cover |
JP6293793B2 (ja) * | 2013-02-08 | 2018-03-14 | エシコン・エンド−サージェリィ・インコーポレイテッドEthicon Endo−Surgery,Inc. | 着脱可能な材料層と同材料層を有する外科用エンドエフェクタ |
US9504470B2 (en) | 2013-02-25 | 2016-11-29 | Covidien Lp | Circular stapling device with buttress |
US20140239047A1 (en) | 2013-02-28 | 2014-08-28 | Covidien Lp | Adherence concepts for non-woven absorbable felt buttresses |
US9782173B2 (en) | 2013-03-07 | 2017-10-10 | Covidien Lp | Circular stapling device including buttress release mechanism |
US9717498B2 (en) | 2013-03-13 | 2017-08-01 | Covidien Lp | Surgical stapling apparatus |
US9655620B2 (en) | 2013-10-28 | 2017-05-23 | Covidien Lp | Circular surgical stapling device including buttress material |
US9936950B2 (en) | 2013-11-08 | 2018-04-10 | Ethicon Llc | Hybrid adjunct materials for use in surgical stapling |
US10561417B2 (en) | 2013-12-09 | 2020-02-18 | Covidien Lp | Adapter assembly for interconnecting electromechanical surgical devices and surgical loading units, and surgical systems thereof |
US9844378B2 (en) | 2014-04-29 | 2017-12-19 | Covidien Lp | Surgical stapling apparatus and methods of adhering a surgical buttress thereto |
US10342542B2 (en) | 2015-08-24 | 2019-07-09 | Ethicon Llc | Surgical stapler buttress applicator with end effector actuated release mechanism |
US10524788B2 (en) * | 2015-09-30 | 2020-01-07 | Ethicon Llc | Compressible adjunct with attachment regions |
US10499918B2 (en) * | 2015-10-29 | 2019-12-10 | Ethicon Llc | Surgical stapler buttress assembly with features to interact with movable end effector components |
US10959731B2 (en) * | 2016-06-14 | 2021-03-30 | Covidien Lp | Buttress attachment for surgical stapling instrument |
US11026686B2 (en) * | 2016-11-08 | 2021-06-08 | Covidien Lp | Structure for attaching buttress to anvil and/or cartridge of surgical stapling instrument |
US10945733B2 (en) * | 2017-08-23 | 2021-03-16 | Covidien Lp | Surgical buttress reload and tip attachment assemblies for surgical stapling apparatus |
US11065000B2 (en) * | 2018-02-22 | 2021-07-20 | Covidien Lp | Surgical buttresses for surgical stapling apparatus |
US11426163B2 (en) * | 2018-05-09 | 2022-08-30 | Covidien Lp | Universal linear surgical stapling buttress |
US10952729B2 (en) * | 2018-10-03 | 2021-03-23 | Covidien Lp | Universal linear buttress retention/release assemblies and methods |
US11523824B2 (en) * | 2019-12-12 | 2022-12-13 | Covidien Lp | Anvil buttress loading for a surgical stapling apparatus |
US11272937B2 (en) * | 2020-01-22 | 2022-03-15 | Covidien Lp | Surgical staple cartridge for supporting surgical buttress material |
US20210290227A1 (en) * | 2020-03-19 | 2021-09-23 | Covidien Lp | Surgical buttresses for surgical stapling apparatus |
-
2018
- 2018-10-03 US US16/150,301 patent/US10952729B2/en active Active
-
2019
- 2019-08-27 CA CA3053111A patent/CA3053111A1/en active Pending
- 2019-08-27 AU AU2019222817A patent/AU2019222817A1/en not_active Abandoned
- 2019-09-18 JP JP2019169322A patent/JP7393165B2/ja active Active
- 2019-10-02 ES ES19200984T patent/ES2886205T3/es active Active
- 2019-10-02 EP EP19200984.3A patent/EP3632342B1/en active Active
-
2021
- 2021-02-22 US US17/181,000 patent/US11627964B2/en active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003000603A (ja) * | 2001-05-07 | 2003-01-07 | Ethicon Endo Surgery Inc | 外科用組織ステープリング器具及び外科用ステープリング器具へのバットレス材料の取付け組立体 |
JP2010142636A (ja) * | 2008-12-16 | 2010-07-01 | Tyco Healthcare Group Lp | 外科用バットレスを含む外科用装置 |
JP2014018666A (ja) * | 2012-07-18 | 2014-02-03 | Covidien Lp | 外科用バットレスを含む外科用装置 |
WO2018152102A1 (en) * | 2017-02-17 | 2018-08-23 | Ethicon Llc | Hybrid mechanism for attachment of an adjunct to a surgical instrument |
US20180256164A1 (en) * | 2017-03-09 | 2018-09-13 | Covidien Lp | Structure for attaching buttress material to anvil and cartridge of surgical stapling instrument |
Also Published As
Publication number | Publication date |
---|---|
AU2019222817A1 (en) | 2020-04-23 |
EP3632342B1 (en) | 2021-07-21 |
CA3053111A1 (en) | 2020-04-03 |
US20200107830A1 (en) | 2020-04-09 |
US10952729B2 (en) | 2021-03-23 |
US11627964B2 (en) | 2023-04-18 |
JP7393165B2 (ja) | 2023-12-06 |
US20210169480A1 (en) | 2021-06-10 |
EP3632342A3 (en) | 2020-06-17 |
EP3632342A2 (en) | 2020-04-08 |
ES2886205T3 (es) | 2021-12-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP7393165B2 (ja) | 汎用線形バットレス保持/解放アセンブリおよび方法 | |
JP7261274B2 (ja) | 外科手術用ステープル留め器具のためのバットレス取り付け | |
US11596404B2 (en) | Structure for attaching buttress to anvil and/or cartridge of surgical stapling instrument | |
US11272932B2 (en) | Structure for attaching buttress material to anvil and cartridge of surgical stapling instrument | |
US8210414B2 (en) | Staple buttress retention system | |
JP2024524126A (ja) | バットレス保持アセンブリを備える外科用ステープル留めデバイス | |
US11786248B2 (en) | Surgical stapling device including a buttress retention assembly | |
AU2015200658B2 (en) | Staple buttress retention system |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20220905 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20230630 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20230705 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20230921 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20231114 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20231124 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 7393165 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |