JP2019536816A5 - - Google Patents
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- Publication number
- JP2019536816A5 JP2019536816A5 JP2019547198A JP2019547198A JP2019536816A5 JP 2019536816 A5 JP2019536816 A5 JP 2019536816A5 JP 2019547198 A JP2019547198 A JP 2019547198A JP 2019547198 A JP2019547198 A JP 2019547198A JP 2019536816 A5 JP2019536816 A5 JP 2019536816A5
- Authority
- JP
- Japan
- Prior art keywords
- dose
- pharmaceutical composition
- composition according
- irbesartan
- blocker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 22
- 239000002947 C09CA04 - Irbesartan Substances 0.000 claims 8
- ZPBWCRDSRKPIDG-UHFFFAOYSA-N amlodipine benzenesulfonate Chemical group OS(=O)(=O)C1=CC=CC=C1.CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1Cl ZPBWCRDSRKPIDG-UHFFFAOYSA-N 0.000 claims 8
- YCPOHTHPUREGFM-UHFFFAOYSA-N irbesartan Chemical group O=C1N(CC=2C=CC(=CC=2)C=2C(=CC=CC=2)C=2[N]N=NN=2)C(CCCC)=NC21CCCC2 YCPOHTHPUREGFM-UHFFFAOYSA-N 0.000 claims 8
- 229960002198 irbesartan Drugs 0.000 claims 8
- 229960000528 amlodipine Drugs 0.000 claims 6
- 238000011282 treatment Methods 0.000 claims 6
- METKIMKYRPQLGS-GFCCVEGCSA-N (R)-atenolol Chemical group CC(C)NC[C@@H](O)COC1=CC=C(CC(N)=O)C=C1 METKIMKYRPQLGS-GFCCVEGCSA-N 0.000 claims 4
- RZPZLFIUFMNCLY-WLHGVMLRSA-N (e)-but-2-enedioic acid;1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol Chemical group OC(=O)\C=C\C(O)=O.CC(C)NCC(O)COC1=CC=C(COCCOC(C)C)C=C1 RZPZLFIUFMNCLY-WLHGVMLRSA-N 0.000 claims 4
- 102000008873 Angiotensin II receptor Human genes 0.000 claims 4
- 108050000824 Angiotensin II receptor Proteins 0.000 claims 4
- 229940127291 Calcium channel antagonist Drugs 0.000 claims 4
- JZUFKLXOESDKRF-UHFFFAOYSA-N Chlorothiazide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC2=C1NCNS2(=O)=O JZUFKLXOESDKRF-UHFFFAOYSA-N 0.000 claims 4
- 229960002274 atenolol Drugs 0.000 claims 4
- 239000002876 beta blocker Substances 0.000 claims 4
- 229940097320 beta blocking agent Drugs 0.000 claims 4
- 229960005400 bisoprolol fumarate Drugs 0.000 claims 4
- 239000002934 diuretic Substances 0.000 claims 4
- 229960002003 hydrochlorothiazide Drugs 0.000 claims 4
- NDDAHWYSQHTHNT-UHFFFAOYSA-N indapamide Chemical compound CC1CC2=CC=CC=C2N1NC(=O)C1=CC=C(Cl)C(S(N)(=O)=O)=C1 NDDAHWYSQHTHNT-UHFFFAOYSA-N 0.000 claims 4
- 229960004569 indapamide Drugs 0.000 claims 4
- 239000003087 receptor blocking agent Substances 0.000 claims 4
- 239000000480 calcium channel blocker Substances 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 206010020772 Hypertension Diseases 0.000 claims 2
- 229960004005 amlodipine besylate Drugs 0.000 claims 2
- 230000035487 diastolic blood pressure Effects 0.000 claims 2
- 230000001882 diuretic effect Effects 0.000 claims 2
- 229940030606 diuretics Drugs 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 230000035488 systolic blood pressure Effects 0.000 claims 2
- FFFHZYDWPBMWHY-VKHMYHEASA-N L-homocysteine Chemical compound OC(=O)[C@@H](N)CCS FFFHZYDWPBMWHY-VKHMYHEASA-N 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 238000011221 initial treatment Methods 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023017160A JP2023095844A (ja) | 2016-11-15 | 2023-02-07 | 高血圧の処置のための組成物 |
| JP2025036716A JP2025102796A (ja) | 2016-11-15 | 2025-03-07 | 高血圧の処置のための組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/352,425 | 2016-11-15 | ||
| US15/352,425 US10369156B2 (en) | 2016-11-15 | 2016-11-15 | Compositions for the treatment of hypertension |
| PCT/IB2017/001524 WO2018091967A1 (en) | 2016-11-15 | 2017-11-14 | Compositions for the treatment of hypertension |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023017160A Division JP2023095844A (ja) | 2016-11-15 | 2023-02-07 | 高血圧の処置のための組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019536816A JP2019536816A (ja) | 2019-12-19 |
| JP2019536816A5 true JP2019536816A5 (enExample) | 2020-12-24 |
Family
ID=62107049
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019547198A Pending JP2019536816A (ja) | 2016-11-15 | 2017-11-14 | 高血圧の処置のための組成物 |
| JP2023017160A Pending JP2023095844A (ja) | 2016-11-15 | 2023-02-07 | 高血圧の処置のための組成物 |
| JP2025036716A Pending JP2025102796A (ja) | 2016-11-15 | 2025-03-07 | 高血圧の処置のための組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023017160A Pending JP2023095844A (ja) | 2016-11-15 | 2023-02-07 | 高血圧の処置のための組成物 |
| JP2025036716A Pending JP2025102796A (ja) | 2016-11-15 | 2025-03-07 | 高血圧の処置のための組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10369156B2 (enExample) |
| EP (2) | EP4574136A3 (enExample) |
| JP (3) | JP2019536816A (enExample) |
| CN (2) | CN110366414A (enExample) |
| AU (3) | AU2017359607A1 (enExample) |
| CA (1) | CA3043835A1 (enExample) |
| TW (1) | TWI799397B (enExample) |
| WO (1) | WO2018091967A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10369156B2 (en) | 2016-11-15 | 2019-08-06 | The George Institute for Global Health | Compositions for the treatment of hypertension |
| MX2019008813A (es) | 2017-01-25 | 2020-02-12 | The George Inst For Global Health | Composiciones para el tratamiento de la hipertension. |
| CA3103599A1 (en) * | 2018-06-14 | 2019-12-19 | Astrazeneca Uk Limited | Methods for treatment of hypertension with an angiotensin ii receptor blocker pharmaceutical composition |
| CN112955965B (zh) * | 2018-06-14 | 2024-04-09 | 阿斯利康(英国)有限公司 | 使用二氢吡啶类钙通道阻断剂医药组合物降低血压的方法 |
| EP3826633A4 (en) * | 2018-07-26 | 2022-04-27 | The George Institute For Global Health | COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION |
| WO2020041864A1 (en) * | 2018-08-25 | 2020-03-05 | Crd Pharmaceuticals Inc. | Synchronize hypertensive therapy with circadian rhythm |
| EP4649946A1 (en) * | 2024-05-16 | 2025-11-19 | Alba Research S.r.l. | Compositions for treating arterial hypertension |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001076632A1 (en) | 2000-04-10 | 2001-10-18 | Wald Nicholas J | Formulation for the prevention of cardiovascular disease |
| GB2361185A (en) | 2000-04-10 | 2001-10-17 | Nicholas J Wald | Pharmaceutical formulation for the prevention of cardiovascular disease |
| AU2002226365A1 (en) * | 2000-12-01 | 2002-06-11 | Novartis Ag | Combinations of an angiotensin receptor antagonist and an anti-hypertensive drug or a statin, for the treatment of sexual dysfunction |
| EG24716A (en) | 2002-05-17 | 2010-06-07 | Novartis Ag | Combination of organic compounds |
| US20040198789A1 (en) | 2003-02-28 | 2004-10-07 | Recordati Ireland Limited | Lercanidipine/ARB/diuretic therapeutic combinations |
| WO2005070463A2 (en) | 2004-01-12 | 2005-08-04 | Sepracor, Inc. | Compositions comprising (s)-amlodipine malate and an angiotensin receptor blocker and methods of their use |
| EP1734958A1 (en) * | 2004-04-06 | 2006-12-27 | Merck & Co., Inc. | Methods for the treatment of hypertension |
| US20070196510A1 (en) | 2006-02-17 | 2007-08-23 | Gerber Michael J | Method for treating resistant hypertension |
| JP2009256209A (ja) * | 2006-02-17 | 2009-11-05 | Gilead Colorado Inc | 降圧療法 |
| CA2655144A1 (en) | 2006-06-15 | 2007-12-21 | Gilead Colorado, Inc. | Antihypertensive therapy method |
| CA2904447C (en) | 2007-08-22 | 2017-01-03 | Abbvie Deutschland Gmbh & Co Kg | Therapy for complications of diabetes |
| CN101450211A (zh) | 2007-12-07 | 2009-06-10 | 上海艾力斯医药科技有限公司 | 复方降压制剂 |
| WO2011149438A1 (en) | 2010-05-28 | 2011-12-01 | Mahmut Bilgic | Combination of antihypertensive agents |
| CN101966190A (zh) | 2010-07-17 | 2011-02-09 | 邬林祥 | 一种治疗高血压含氨氯地平和依普罗沙坦的复方制剂 |
| CN102225203A (zh) | 2011-06-29 | 2011-10-26 | 北京阜康仁生物制药科技有限公司 | 一种用于降低血压的药用组合物 |
| US10918612B2 (en) | 2013-01-22 | 2021-02-16 | Markus Zwickl | Combinations with 2-aminoethanesulfonic acid |
| CN106310278A (zh) | 2016-08-01 | 2017-01-11 | 深圳奥萨制药有限公司 | 一种含叶酸的多联降压药物组合物 |
| US10369156B2 (en) | 2016-11-15 | 2019-08-06 | The George Institute for Global Health | Compositions for the treatment of hypertension |
| MX2019008813A (es) | 2017-01-25 | 2020-02-12 | The George Inst For Global Health | Composiciones para el tratamiento de la hipertension. |
-
2016
- 2016-11-15 US US15/352,425 patent/US10369156B2/en active Active
-
2017
- 2017-11-14 CN CN201780083502.7A patent/CN110366414A/zh active Pending
- 2017-11-14 WO PCT/IB2017/001524 patent/WO2018091967A1/en not_active Ceased
- 2017-11-14 JP JP2019547198A patent/JP2019536816A/ja active Pending
- 2017-11-14 EP EP25167728.2A patent/EP4574136A3/en active Pending
- 2017-11-14 EP EP17871454.9A patent/EP3541379A4/en active Pending
- 2017-11-14 CN CN202310591252.5A patent/CN116603066A/zh active Pending
- 2017-11-14 CA CA3043835A patent/CA3043835A1/en active Pending
- 2017-11-14 AU AU2017359607A patent/AU2017359607A1/en not_active Abandoned
- 2017-11-15 TW TW106139407A patent/TWI799397B/zh active
-
2018
- 2018-12-11 US US16/216,840 patent/US20190314383A1/en not_active Abandoned
-
2023
- 2023-02-07 JP JP2023017160A patent/JP2023095844A/ja active Pending
- 2023-11-01 AU AU2023258387A patent/AU2023258387B2/en active Active
-
2025
- 2025-03-07 JP JP2025036716A patent/JP2025102796A/ja active Pending
- 2025-08-04 AU AU2025210908A patent/AU2025210908A1/en active Pending
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