JP2019536816A - 高血圧の処置のための組成物 - Google Patents

高血圧の処置のための組成物 Download PDF

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Publication number
JP2019536816A
JP2019536816A JP2019547198A JP2019547198A JP2019536816A JP 2019536816 A JP2019536816 A JP 2019536816A JP 2019547198 A JP2019547198 A JP 2019547198A JP 2019547198 A JP2019547198 A JP 2019547198A JP 2019536816 A JP2019536816 A JP 2019536816A
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Prior art keywords
dose
pharmaceutical composition
diuretic
composition according
treatment
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JP2019547198A
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English (en)
Japanese (ja)
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JP2019536816A5 (enExample
Inventor
ロジャース，アンソニー
チャウ，クララ
Original Assignee
ザ ジョージ インスティテュート フォー グローバル ヘルス
ザ ジョージ インスティテュート フォー グローバル ヘルス
ザ ユニバーシティー オブ シドニー
ザ ユニバーシティー オブ シドニー
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Application filed by ザ ジョージ インスティテュート フォー グローバル ヘルス, ザ ジョージ インスティテュート フォー グローバル ヘルス, ザ ユニバーシティー オブ シドニー, ザ ユニバーシティー オブ シドニー filed Critical ザ ジョージ インスティテュート フォー グローバル ヘルス
Publication of JP2019536816A publication Critical patent/JP2019536816A/ja
Publication of JP2019536816A5 publication Critical patent/JP2019536816A5/ja
Priority to JP2023017160A priority Critical patent/JP2023095844A/ja
Priority to JP2025036716A priority patent/JP2025102796A/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2019547198A 2016-11-15 2017-11-14 高血圧の処置のための組成物 Pending JP2019536816A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023017160A JP2023095844A (ja) 2016-11-15 2023-02-07 高血圧の処置のための組成物
JP2025036716A JP2025102796A (ja) 2016-11-15 2025-03-07 高血圧の処置のための組成物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15/352,425 US10369156B2 (en) 2016-11-15 2016-11-15 Compositions for the treatment of hypertension
US15/352,425 2016-11-15
PCT/IB2017/001524 WO2018091967A1 (en) 2016-11-15 2017-11-14 Compositions for the treatment of hypertension

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023017160A Division JP2023095844A (ja) 2016-11-15 2023-02-07 高血圧の処置のための組成物

Publications (2)

Publication Number Publication Date
JP2019536816A true JP2019536816A (ja) 2019-12-19
JP2019536816A5 JP2019536816A5 (enExample) 2020-12-24

Family

ID=62107049

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019547198A Pending JP2019536816A (ja) 2016-11-15 2017-11-14 高血圧の処置のための組成物
JP2023017160A Pending JP2023095844A (ja) 2016-11-15 2023-02-07 高血圧の処置のための組成物
JP2025036716A Pending JP2025102796A (ja) 2016-11-15 2025-03-07 高血圧の処置のための組成物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023017160A Pending JP2023095844A (ja) 2016-11-15 2023-02-07 高血圧の処置のための組成物
JP2025036716A Pending JP2025102796A (ja) 2016-11-15 2025-03-07 高血圧の処置のための組成物

Country Status (8)

Country Link
US (2) US10369156B2 (enExample)
EP (2) EP4574136A3 (enExample)
JP (3) JP2019536816A (enExample)
CN (2) CN110366414A (enExample)
AU (3) AU2017359607A1 (enExample)
CA (1) CA3043835A1 (enExample)
TW (1) TWI799397B (enExample)
WO (1) WO2018091967A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10369156B2 (en) 2016-11-15 2019-08-06 The George Institute for Global Health Compositions for the treatment of hypertension
AU2018213147B2 (en) 2017-01-25 2023-08-31 The George Institute for Global Health Compositions for the treatment of hypertension
AU2019285170A1 (en) * 2018-06-14 2021-01-28 Astrazeneca Uk Limited Methods for lowering blood pressure with a dihydropyridine-type calcium channel blocker pharmaceutical composition
JP2021528735A (ja) * 2018-06-14 2021-10-21 アストラゼネカ・ユーケイ・リミテッドＡｓｔｒａＺｅｎｅｃａ ＵＫ Ｌｉｍｉｔｅｄ アンジオテンシンｉｉ受容体遮断薬医薬組成物による高血圧症の治療方法
BR112021001374A2 (pt) * 2018-07-26 2021-07-06 The George Inst For Global Health composições para o tratamento da hipertensão
JP2021536443A (ja) * 2018-08-25 2021-12-27 シーアールディー ファーマシューティカルズ インコーポレイティド 高血圧治療をサーカディアンリズムと同期させる
EP4649946A1 (en) * 2024-05-16 2025-11-19 Alba Research S.r.l. Compositions for treating arterial hypertension

Citations (2)

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JP2004514703A (ja) * 2000-12-01 2004-05-20 ノバルティス　アクチエンゲゼルシャフト 有機化合物の組合せ剤
JP2009256209A (ja) * 2006-02-17 2009-11-05 Gilead Colorado Inc 降圧療法

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EP1272220B2 (en) 2000-04-10 2016-07-27 Nicholas John Wald Formulation for the prevention of cardiovascular disease
GB2361185A (en) 2000-04-10 2001-10-17 Nicholas J Wald Pharmaceutical formulation for the prevention of cardiovascular disease
EG24716A (en) 2002-05-17 2010-06-07 Novartis Ag Combination of organic compounds
US20040198789A1 (en) 2003-02-28 2004-10-07 Recordati Ireland Limited Lercanidipine/ARB/diuretic therapeutic combinations
WO2005070462A2 (en) 2004-01-12 2005-08-04 Sepracor, Inc. Compositions comprising (s)-amlodipine and an angiotensin receptor blocker and methods of their use
EP1734958A1 (en) * 2004-04-06 2006-12-27 Merck & Co., Inc. Methods for the treatment of hypertension
US20070196510A1 (en) 2006-02-17 2007-08-23 Gerber Michael J Method for treating resistant hypertension
WO2007146900A2 (en) 2006-06-15 2007-12-21 Gilead Colorado, Inc. Antihypertensive therapy method
CA2697057A1 (en) 2007-08-22 2009-02-26 Gilead Colorado, Inc. Therapy for complications of diabetes
CN101450211A (zh) 2007-12-07 2009-06-10 上海艾力斯医药科技有限公司 复方降压制剂
WO2011149438A1 (en) 2010-05-28 2011-12-01 Mahmut Bilgic Combination of antihypertensive agents
CN101966190A (zh) 2010-07-17 2011-02-09 邬林祥 一种治疗高血压含氨氯地平和依普罗沙坦的复方制剂
CN102225203A (zh) 2011-06-29 2011-10-26 北京阜康仁生物制药科技有限公司 一种用于降低血压的药用组合物
US10918612B2 (en) 2013-01-22 2021-02-16 Markus Zwickl Combinations with 2-aminoethanesulfonic acid
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US10369156B2 (en) 2016-11-15 2019-08-06 The George Institute for Global Health Compositions for the treatment of hypertension
AU2018213147B2 (en) 2017-01-25 2023-08-31 The George Institute for Global Health Compositions for the treatment of hypertension

Patent Citations (2)

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JP2004514703A (ja) * 2000-12-01 2004-05-20 ノバルティス　アクチエンゲゼルシャフト 有機化合物の組合せ剤
JP2009256209A (ja) * 2006-02-17 2009-11-05 Gilead Colorado Inc 降圧療法

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Title
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Also Published As

Publication number Publication date
AU2025210908A1 (en) 2025-08-21
EP4574136A3 (en) 2025-09-17
TW201828988A (zh) 2018-08-16
WO2018091967A1 (en) 2018-05-24
CN116603066A (zh) 2023-08-18
CN110366414A (zh) 2019-10-22
AU2023258387B2 (en) 2025-05-29
US10369156B2 (en) 2019-08-06
JP2025102796A (ja) 2025-07-08
AU2017359607A1 (en) 2019-06-06
US20180133227A1 (en) 2018-05-17
AU2023258387A1 (en) 2023-11-23
EP3541379A4 (en) 2020-05-27
BR112019009859A2 (pt) 2019-08-20
JP2023095844A (ja) 2023-07-06
TWI799397B (zh) 2023-04-21
US20190314383A1 (en) 2019-10-17
EP3541379A1 (en) 2019-09-25
CA3043835A1 (en) 2018-05-24
EP4574136A2 (en) 2025-06-25

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