JP2019533714A5 - - Google Patents
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- JP2019533714A5 JP2019533714A5 JP2019524943A JP2019524943A JP2019533714A5 JP 2019533714 A5 JP2019533714 A5 JP 2019533714A5 JP 2019524943 A JP2019524943 A JP 2019524943A JP 2019524943 A JP2019524943 A JP 2019524943A JP 2019533714 A5 JP2019533714 A5 JP 2019533714A5
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- JP
- Japan
- Prior art keywords
- alkyl
- halogen
- cycloalkyl
- case
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 0 Cc1cc(*)c(*)c(*)c1 Chemical compound Cc1cc(*)c(*)c(*)c1 0.000 description 3
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023000165A JP2023033259A (ja) | 2016-11-11 | 2023-01-04 | 脂質合成の複素環式モジュレーター |
| JP2024229040A JP2025036565A (ja) | 2016-11-11 | 2024-12-25 | 脂質合成の複素環式モジュレーター |
| JP2026036572A JP2026088159A (ja) | 2016-11-11 | 2026-03-06 | 脂質合成の複素環式モジュレーター |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/349,960 | 2016-11-11 | ||
| US15/349,960 US20170119786A1 (en) | 2011-03-08 | 2016-11-11 | Heterocyclic modulators of lipid synthesis |
| US201762574497P | 2017-10-19 | 2017-10-19 | |
| US62/574,497 | 2017-10-19 | ||
| PCT/US2017/061330 WO2018089904A1 (en) | 2016-11-11 | 2017-11-13 | Heterocyclic modulators of lipid synthesis |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023000165A Division JP2023033259A (ja) | 2016-11-11 | 2023-01-04 | 脂質合成の複素環式モジュレーター |
| JP2024229040A Division JP2025036565A (ja) | 2016-11-11 | 2024-12-25 | 脂質合成の複素環式モジュレーター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019533714A JP2019533714A (ja) | 2019-11-21 |
| JP2019533714A5 true JP2019533714A5 (enExample) | 2020-12-10 |
| JP7668509B2 JP7668509B2 (ja) | 2025-04-25 |
Family
ID=60473676
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019524943A Active JP7668509B2 (ja) | 2016-11-11 | 2017-11-13 | 脂質合成の複素環式モジュレーター |
| JP2023000165A Pending JP2023033259A (ja) | 2016-11-11 | 2023-01-04 | 脂質合成の複素環式モジュレーター |
| JP2024229040A Withdrawn JP2025036565A (ja) | 2016-11-11 | 2024-12-25 | 脂質合成の複素環式モジュレーター |
| JP2026036572A Pending JP2026088159A (ja) | 2016-11-11 | 2026-03-06 | 脂質合成の複素環式モジュレーター |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023000165A Pending JP2023033259A (ja) | 2016-11-11 | 2023-01-04 | 脂質合成の複素環式モジュレーター |
| JP2024229040A Withdrawn JP2025036565A (ja) | 2016-11-11 | 2024-12-25 | 脂質合成の複素環式モジュレーター |
| JP2026036572A Pending JP2026088159A (ja) | 2016-11-11 | 2026-03-06 | 脂質合成の複素環式モジュレーター |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11034690B2 (enExample) |
| EP (1) | EP3538088A1 (enExample) |
| JP (4) | JP7668509B2 (enExample) |
| KR (3) | KR102644934B1 (enExample) |
| CN (3) | CN110177551B (enExample) |
| AU (2) | AU2017356214B2 (enExample) |
| CA (1) | CA3043308A1 (enExample) |
| IL (1) | IL266505B2 (enExample) |
| NZ (1) | NZ754372A (enExample) |
| WO (1) | WO2018089904A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170119786A1 (en) | 2011-03-08 | 2017-05-04 | 3-V Biosciences, Inc. | Heterocyclic modulators of lipid synthesis |
| TWI767148B (zh) | 2018-10-10 | 2022-06-11 | 美商弗瑪治療公司 | 抑制脂肪酸合成酶(fasn) |
| CN110078613B (zh) * | 2019-05-31 | 2022-04-22 | 杭州科耀医药科技有限公司 | 一种2-卤-5-碘苯甲酸的合成方法 |
| CN117567338A (zh) | 2019-10-09 | 2024-02-20 | 拜耳公司 | 作为农药的新的杂芳基三唑化合物 |
| CN114469945A (zh) * | 2020-10-28 | 2022-05-13 | 歌礼生物科技（杭州）有限公司 | 脂肪酸合酶抑制剂的用途和药物组合物 |
| EP4430535A4 (en) * | 2021-11-11 | 2025-09-17 | Sagimet Biosciences Inc | METHODS FOR PREDICTING TREATMENT RESPONSE IN NONALCOHOLIC FATTY LIVER DISEASE |
| CN114436979B (zh) * | 2022-02-22 | 2024-03-26 | 成都化润药业有限公司 | 一种合成1,2,4-三氮唑-3-羧酸甲酯的方法 |
| JPWO2024172156A1 (enExample) * | 2023-02-16 | 2024-08-22 | ||
| CN119080742A (zh) * | 2023-06-05 | 2024-12-06 | 甘莱制药有限公司 | 脂质合成的杂环调节剂的工业化制备 |
| CN119868349B (zh) * | 2023-10-23 | 2026-05-15 | 歌礼生物科技（杭州）有限公司 | 一种包含苯甲腈衍生物的药物组合物 |
| WO2025086054A1 (zh) * | 2023-10-23 | 2025-05-01 | 歌礼生物科技（杭州）有限公司 | 一种包含苯甲腈衍生物的药物组合物 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6939874B2 (en) | 2001-08-22 | 2005-09-06 | Amgen Inc. | Substituted pyrimidinyl derivatives and methods of use |
| WO2007052843A1 (ja) | 2005-11-04 | 2007-05-10 | Takeda Pharmaceutical Company Limited | 複素環アミド化合物およびその用途 |
| DE602006011363D1 (de) | 2005-12-01 | 2010-02-04 | Hoffmann La Roche | Heteroaryl-substituierte piperidin-derivate als l-cpt1-hemmer |
| AU2007292306A1 (en) | 2006-09-05 | 2008-03-13 | Bipar Sciences, Inc. | Inhibition of fatty acid synthesis by PARP inhibitors and methods of treatment thereof |
| WO2008059214A1 (en) | 2006-11-13 | 2008-05-22 | Astrazeneca Ab | Bisamlde derivatives and use thereof as fatty acid synthase inhibitors |
| WO2008075077A1 (en) | 2006-12-21 | 2008-06-26 | Astrazeneca Ab | Piperidine derivatives for the treatment of obesity |
| TW200833663A (en) | 2006-12-21 | 2008-08-16 | Astrazeneca Ab | Therapeutic agents |
| TW200831092A (en) | 2006-12-21 | 2008-08-01 | Astrazeneca Ab | Therapeutic agents |
| EP2485678A4 (en) | 2009-10-07 | 2013-04-03 | Univ Cornell | Coferons and methods of making and using them |
| JP2013520502A (ja) * | 2010-02-25 | 2013-06-06 | メルク・シャープ・エンド・ドーム・コーポレイション | 有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体 |
| LT2683244T (lt) | 2011-03-08 | 2017-04-10 | 3-V Biosciences, Inc. | Lipidų sintezės heterocikliniai moduliatoriai |
| US9624173B2 (en) | 2011-03-08 | 2017-04-18 | 3-V Biosciences, Inc. | Heterocyclic modulators of lipid synthesis |
| US20170119786A1 (en) | 2011-03-08 | 2017-05-04 | 3-V Biosciences, Inc. | Heterocyclic modulators of lipid synthesis |
| TWI522348B (zh) | 2011-03-08 | 2016-02-21 | ３ Ｖ生物科技公司 | 脂質合成之雜環調節劑 |
| KR102071095B1 (ko) | 2012-07-03 | 2020-01-29 | 3-브이 바이오사이언시스, 인코포레이티드 | 지질 합성의 헤테로사이클릭 조절인자 |
| WO2014039769A1 (en) | 2012-09-07 | 2014-03-13 | Janssen Pharmaceutica Nv | Imidazolin-5-one derivatives useful as fatty acid snthase (fasn) inhibitors for|the treatment of cancer |
| CA2932396C (en) * | 2013-12-03 | 2022-03-29 | Janssen Pharmaceutica Nv | Benzamide derivative useful as fasn inhibitors for the treatment of cancer |
| CA2934257C (en) * | 2013-12-17 | 2022-06-07 | Janssen Pharmaceutica Nv | Imidazolin-5-one derivative useful as fasn inhibitors for the treatment of cancer |
| CA2934251C (en) | 2013-12-20 | 2024-01-02 | 3-V Biosciences, Inc. | A combination of heterocyclic modulators of lipid synthesis and chemotherapeutic drugs in treatment of cancer |
| JP6522007B2 (ja) * | 2014-01-07 | 2019-05-29 | ３−ブイ・バイオサイエンシーズ・インコーポレイテッド３−Ｖ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． | 癌及びウイルス感染症に対する使用のための脂質合成の複素環式モジュレータ |
| CU24395B1 (es) * | 2014-03-17 | 2019-04-04 | Pfizer | Inhibidores de diacilglicerol aciltransferasa 2 |
| ES2833454T3 (es) | 2014-08-15 | 2021-06-15 | Sagimet Biosciences Inc | Inhibidor de la ácido graso sintasa para su uso en el tratamiento de un cáncer farmacorresistente |
| JP6758314B2 (ja) | 2015-03-19 | 2020-09-23 | サギメット バイオサイエンシーズ インコーポレイテッド | 脂質合成の複素環式調節因子 |
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2017
- 2017-11-13 KR KR1020197016754A patent/KR102644934B1/ko active Active
- 2017-11-13 KR KR1020257039033A patent/KR20250169632A/ko active Pending
- 2017-11-13 CN CN201780083446.7A patent/CN110177551B/zh active Active
- 2017-11-13 CA CA3043308A patent/CA3043308A1/en active Pending
- 2017-11-13 JP JP2019524943A patent/JP7668509B2/ja active Active
- 2017-11-13 US US16/348,138 patent/US11034690B2/en active Active
- 2017-11-13 CN CN202512049345.7A patent/CN121774967A/zh active Pending
- 2017-11-13 CN CN202310077929.3A patent/CN116139138A/zh active Pending
- 2017-11-13 KR KR1020247007294A patent/KR102890891B1/ko active Active
- 2017-11-13 EP EP17804772.6A patent/EP3538088A1/en active Pending
- 2017-11-13 AU AU2017356214A patent/AU2017356214B2/en active Active
- 2017-11-13 NZ NZ754372A patent/NZ754372A/en unknown
- 2017-11-13 WO PCT/US2017/061330 patent/WO2018089904A1/en not_active Ceased
-
2019
- 2019-05-07 IL IL266505A patent/IL266505B2/en unknown
-
2023
- 2023-01-04 JP JP2023000165A patent/JP2023033259A/ja active Pending
-
2024
- 2024-02-19 AU AU2024201067A patent/AU2024201067B2/en active Active
- 2024-12-25 JP JP2024229040A patent/JP2025036565A/ja not_active Withdrawn
-
2026
- 2026-03-06 JP JP2026036572A patent/JP2026088159A/ja active Pending