JP2019532071A5 - - Google Patents
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- Publication number
- JP2019532071A5 JP2019532071A5 JP2019520039A JP2019520039A JP2019532071A5 JP 2019532071 A5 JP2019532071 A5 JP 2019532071A5 JP 2019520039 A JP2019520039 A JP 2019520039A JP 2019520039 A JP2019520039 A JP 2019520039A JP 2019532071 A5 JP2019532071 A5 JP 2019532071A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound according
- hydrogen
- halo
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022113322A JP2022132464A (ja) | 2016-10-14 | 2022-07-14 | 非常に強力な糖質コルチコイドの構造およびデザインのための機構 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662408314P | 2016-10-14 | 2016-10-14 | |
| US62/408,314 | 2016-10-14 | ||
| PCT/US2017/056447 WO2018071736A1 (en) | 2016-10-14 | 2017-10-13 | Structures and mechanism for the design of highly potent glucocorticoids |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022113322A Division JP2022132464A (ja) | 2016-10-14 | 2022-07-14 | 非常に強力な糖質コルチコイドの構造およびデザインのための機構 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019532071A JP2019532071A (ja) | 2019-11-07 |
| JP2019532071A5 true JP2019532071A5 (enExample) | 2020-11-12 |
| JP7146750B2 JP7146750B2 (ja) | 2022-10-04 |
Family
ID=61906432
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019520039A Active JP7146750B2 (ja) | 2016-10-14 | 2017-10-13 | 非常に強力な糖質コルチコイドの構造およびデザインのための機構 |
| JP2022113322A Withdrawn JP2022132464A (ja) | 2016-10-14 | 2022-07-14 | 非常に強力な糖質コルチコイドの構造およびデザインのための機構 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022113322A Withdrawn JP2022132464A (ja) | 2016-10-14 | 2022-07-14 | 非常に強力な糖質コルチコイドの構造およびデザインのための機構 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10954265B2 (enExample) |
| EP (1) | EP3525870B1 (enExample) |
| JP (2) | JP7146750B2 (enExample) |
| KR (1) | KR102497070B1 (enExample) |
| CN (1) | CN110382033B (enExample) |
| ES (1) | ES2945983T3 (enExample) |
| MA (1) | MA46539A (enExample) |
| PH (1) | PH12019500801A1 (enExample) |
| RU (1) | RU2019111101A (enExample) |
| SG (1) | SG11201903209TA (enExample) |
| WO (1) | WO2018071736A1 (enExample) |
| ZA (1) | ZA201902595B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025119398A1 (zh) * | 2023-12-08 | 2025-06-12 | 浙江柏拉阿图医药科技有限公司 | 高效力糖皮质激素多晶型及其制备方法和用途 |
| CN120365344A (zh) * | 2024-01-24 | 2025-07-25 | 浙江柏拉阿图医药科技有限公司 | 一种高效力糖皮质激素化合物及其制备和用途 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK66202C (da) | 1945-03-03 | 1948-01-12 | Danske Securitas As | Kodekontakt til elektriske Alarmanlæg. |
| DK71662C (da) | 1946-09-05 | 1950-11-06 | Ingenioer Frank Broadbent | Tørrecentrifuge. |
| US4049813A (en) | 1976-07-15 | 1977-09-20 | Sandoz, Inc. | Substituted isoxazolo pyridinones |
| US5837698A (en) * | 1996-05-02 | 1998-11-17 | G. D. Searle & Co. | Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs |
| EP1408042A4 (en) | 2001-06-14 | 2005-02-02 | Banyu Pharma Co Ltd | NEW ISOXAZOLOPYRIDONE DERIVATIVES AND THEIR USE |
| GB0119911D0 (en) | 2001-08-15 | 2001-10-10 | Novartis Ag | Organic Compounds |
| SG148186A1 (en) * | 2003-11-13 | 2008-12-31 | Combinatorx Inc | Methods and reagents for the treatment of inflammatory disorders |
| CA2621117A1 (en) * | 2005-09-02 | 2007-03-08 | Nicox S.A. | Steroids nitrooxyderivatives |
| CN1813768A (zh) * | 2005-11-18 | 2006-08-09 | 成都力思特制药股份有限公司 | 治疗呼吸系统疾病的药用组合物及其在制药中的应用 |
| AU2008306593C1 (en) * | 2007-10-04 | 2012-10-04 | Astrazeneca Ab | Steroidal [3, 2-C] pyrazole compounds, with glucocorticoid activity |
| CA2707618A1 (en) * | 2007-12-20 | 2009-07-02 | Astrazeneca Ab | Steroid derivatives acting as glucocorticosteroid receptor agonists |
| WO2010083218A1 (en) | 2009-01-13 | 2010-07-22 | Van Andel Research Institute | Methods of using substituted isoxazolo pyridinones as dissociated glucocorticoids |
| UY32520A (es) | 2009-04-03 | 2010-10-29 | Astrazeneca Ab | Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides |
| UY32523A (es) * | 2009-04-03 | 2010-10-29 | Astrazeneca Ab | Compuestos que tienen actividad agonista del receptor de glucocorticosteroides |
| UY32525A (es) * | 2009-04-03 | 2010-10-29 | Astrazeneca Ab | Compuestos que tienen actividad agonista del receptor de glucocorticosteroides |
| CA2764830A1 (en) * | 2009-06-16 | 2010-12-23 | Schering Corporation | Novel [3,2-c] heteroaryl steroids as glucocorticoid receptor agonists, compositions and uses thereof |
| EP3049089B1 (en) | 2013-09-25 | 2019-08-21 | Van Andel Research Institute | Highly potent glucocorticoids |
| TWI695831B (zh) * | 2014-09-13 | 2020-06-11 | 香港商南北兄弟藥業投資有限公司 | Ｃｒｔｈ２拮抗劑化合物及其用途 |
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2017
- 2017-10-13 US US16/341,275 patent/US10954265B2/en active Active
- 2017-10-13 RU RU2019111101A patent/RU2019111101A/ru unknown
- 2017-10-13 MA MA046539A patent/MA46539A/fr unknown
- 2017-10-13 KR KR1020197013291A patent/KR102497070B1/ko active Active
- 2017-10-13 ES ES17860202T patent/ES2945983T3/es active Active
- 2017-10-13 SG SG11201903209TA patent/SG11201903209TA/en unknown
- 2017-10-13 EP EP17860202.5A patent/EP3525870B1/en active Active
- 2017-10-13 CN CN201780076320.7A patent/CN110382033B/zh active Active
- 2017-10-13 WO PCT/US2017/056447 patent/WO2018071736A1/en not_active Ceased
- 2017-10-13 JP JP2019520039A patent/JP7146750B2/ja active Active
-
2019
- 2019-04-12 PH PH12019500801A patent/PH12019500801A1/en unknown
- 2019-04-24 ZA ZA2019/02595A patent/ZA201902595B/en unknown
-
2022
- 2022-07-14 JP JP2022113322A patent/JP2022132464A/ja not_active Withdrawn