MA46539A - Structures et mécanisme pour la conception de glucocorticoïdes hautement puissants - Google Patents
Structures et mécanisme pour la conception de glucocorticoïdes hautement puissantsInfo
- Publication number
- MA46539A MA46539A MA046539A MA46539A MA46539A MA 46539 A MA46539 A MA 46539A MA 046539 A MA046539 A MA 046539A MA 46539 A MA46539 A MA 46539A MA 46539 A MA46539 A MA 46539A
- Authority
- MA
- Morocco
- Prior art keywords
- glucocorticoids
- structures
- design
- highly powerful
- powerful
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only
- C07J71/0047—Nitrogen only at position 2(3)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662408314P | 2016-10-14 | 2016-10-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA46539A true MA46539A (fr) | 2019-08-21 |
Family
ID=61906432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA046539A MA46539A (fr) | 2016-10-14 | 2017-10-13 | Structures et mécanisme pour la conception de glucocorticoïdes hautement puissants |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10954265B2 (fr) |
| EP (1) | EP3525870B1 (fr) |
| JP (2) | JP7146750B2 (fr) |
| KR (1) | KR102497070B1 (fr) |
| CN (1) | CN110382033B (fr) |
| ES (1) | ES2945983T3 (fr) |
| MA (1) | MA46539A (fr) |
| PH (1) | PH12019500801A1 (fr) |
| RU (1) | RU2019111101A (fr) |
| SG (1) | SG11201903209TA (fr) |
| WO (1) | WO2018071736A1 (fr) |
| ZA (1) | ZA201902595B (fr) |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK66202C (da) | 1945-03-03 | 1948-01-12 | Danske Securitas As | Kodekontakt til elektriske Alarmanlæg. |
| DK71662C (da) | 1946-09-05 | 1950-11-06 | Ingenioer Frank Broadbent | Tørrecentrifuge. |
| US4049813A (en) | 1976-07-15 | 1977-09-20 | Sandoz, Inc. | Substituted isoxazolo pyridinones |
| US5837698A (en) * | 1996-05-02 | 1998-11-17 | G. D. Searle & Co. | Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs |
| JPWO2002102807A1 (ja) | 2001-06-14 | 2004-09-30 | 萬有製薬株式会社 | 新規イソキサゾロピリドン誘導体及びその用途 |
| GB0119911D0 (en) | 2001-08-15 | 2001-10-10 | Novartis Ag | Organic Compounds |
| EP1691744A4 (fr) * | 2003-11-13 | 2007-12-26 | Combinatorx Inc | Procedes et reactifs pour le traitement de troubles inflammatoires |
| AU2006286838C1 (en) * | 2005-09-02 | 2013-05-02 | Ferrer Internacional S.A. | Nitrooxy derivatives of glucocorticoids |
| CN1813768A (zh) * | 2005-11-18 | 2006-08-09 | 成都力思特制药股份有限公司 | 治疗呼吸系统疾病的药用组合物及其在制药中的应用 |
| MX2010003698A (es) * | 2007-10-04 | 2010-04-21 | Astrazeneca Ab | Compuestos de [3,2-c]pirazol esteroides con actividad glucocorticoide. |
| CA2707618A1 (fr) * | 2007-12-20 | 2009-07-02 | Astrazeneca Ab | Derives de steroides agissant comme des agonistes des recepteurs de glucocorticosteroides |
| CA2749585A1 (fr) | 2009-01-13 | 2010-07-22 | Van Andel Research Institute | Methodes d'utilisation de pyridinones isoxazolo-substituees en tant que glucocorticoides |
| UY32525A (es) * | 2009-04-03 | 2010-10-29 | Astrazeneca Ab | Compuestos que tienen actividad agonista del receptor de glucocorticosteroides |
| UY32520A (es) | 2009-04-03 | 2010-10-29 | Astrazeneca Ab | Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides |
| UY32523A (es) * | 2009-04-03 | 2010-10-29 | Astrazeneca Ab | Compuestos que tienen actividad agonista del receptor de glucocorticosteroides |
| AR077101A1 (es) * | 2009-06-16 | 2011-08-03 | Schering Corp | Esteroides de heteroarilo (3,2-c), como agonistas de receptor glucocorticoide, composiciones y usos de los mismos |
| AU2014324961A1 (en) * | 2013-09-25 | 2016-04-14 | Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences | Highly potent glucocorticoids |
| TWI695831B (zh) * | 2014-09-13 | 2020-06-11 | 香港商南北兄弟藥業投資有限公司 | Ｃｒｔｈ２拮抗劑化合物及其用途 |
-
2017
- 2017-10-13 EP EP17860202.5A patent/EP3525870B1/fr active Active
- 2017-10-13 KR KR1020197013291A patent/KR102497070B1/ko active IP Right Grant
- 2017-10-13 MA MA046539A patent/MA46539A/fr unknown
- 2017-10-13 WO PCT/US2017/056447 patent/WO2018071736A1/fr unknown
- 2017-10-13 JP JP2019520039A patent/JP7146750B2/ja active Active
- 2017-10-13 CN CN201780076320.7A patent/CN110382033B/zh active Active
- 2017-10-13 US US16/341,275 patent/US10954265B2/en active Active
- 2017-10-13 SG SG11201903209TA patent/SG11201903209TA/en unknown
- 2017-10-13 ES ES17860202T patent/ES2945983T3/es active Active
- 2017-10-13 RU RU2019111101A patent/RU2019111101A/ru unknown
-
2019
- 2019-04-12 PH PH12019500801A patent/PH12019500801A1/en unknown
- 2019-04-24 ZA ZA2019/02595A patent/ZA201902595B/en unknown
-
2022
- 2022-07-14 JP JP2022113322A patent/JP2022132464A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2019532071A (ja) | 2019-11-07 |
| WO2018071736A9 (fr) | 2019-05-23 |
| EP3525870B1 (fr) | 2023-05-10 |
| KR102497070B1 (ko) | 2023-02-06 |
| ZA201902595B (en) | 2021-04-28 |
| SG11201903209TA (en) | 2019-05-30 |
| JP7146750B2 (ja) | 2022-10-04 |
| ES2945983T3 (es) | 2023-07-11 |
| PH12019500801A1 (en) | 2019-11-11 |
| EP3525870A4 (fr) | 2020-04-29 |
| RU2019111101A3 (fr) | 2020-11-27 |
| CN110382033A (zh) | 2019-10-25 |
| KR20190068577A (ko) | 2019-06-18 |
| EP3525870A1 (fr) | 2019-08-21 |
| JP2022132464A (ja) | 2022-09-08 |
| RU2019111101A (ru) | 2020-11-16 |
| CN110382033B (zh) | 2022-04-15 |
| WO2018071736A1 (fr) | 2018-04-19 |
| US10954265B2 (en) | 2021-03-23 |
| US20190263853A1 (en) | 2019-08-29 |
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