|
DE2756113A1
(de)
|
1977-12-16 |
1979-06-21 |
Thomae Gmbh Dr K |
Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
|
|
US4172896A
(en)
|
1978-06-05 |
1979-10-30 |
Dainippon Pharmaceutical Co., Ltd. |
Methane-sulfonamide derivatives, the preparation thereof and composition comprising the same
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4885367A
(en)
|
1987-11-19 |
1989-12-05 |
Taisho Pharmaceutical Co., Ltd. |
Sulfonanilide compounds
|
|
GB9217295D0
(en)
|
1992-08-14 |
1992-09-30 |
Wellcome Found |
Controlled released tablets
|
|
EP0764644A1
(en)
|
1993-01-15 |
1997-03-26 |
G.D. Searle & Co. |
Use of medicaments containing 3,4-diaryl furans and analogs thereof for treating a gastrointestinal condition
|
|
CA2113787A1
(en)
|
1993-01-29 |
1994-07-30 |
Nobuyuki Hamanaka |
Carbocyclic sulfonamides
|
|
US5380738A
(en)
|
1993-05-21 |
1995-01-10 |
Monsanto Company |
2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
|
|
US5474995A
(en)
|
1993-06-24 |
1995-12-12 |
Merck Frosst Canada, Inc. |
Phenyl heterocycles as cox-2 inhibitors
|
|
GB9315856D0
(en)
|
1993-07-30 |
1993-09-15 |
Wellcome Found |
Stabilized pharmaceutical
|
|
US5541231A
(en)
|
1993-07-30 |
1996-07-30 |
Glaxo Wellcome Inc. |
Stabilized Pharmaceutical
|
|
US5358970A
(en)
|
1993-08-12 |
1994-10-25 |
Burroughs Wellcome Co. |
Pharmaceutical composition containing bupropion hydrochloride and a stabilizer
|
|
US5344991A
(en)
|
1993-10-29 |
1994-09-06 |
G.D. Searle & Co. |
1,2 diarylcyclopentenyl compounds for the treatment of inflammation
|
|
ES2141916T3
(es)
|
1993-11-30 |
2000-04-01 |
Searle & Co |
Pirazolil-bencenosulfonamidas sustituidas para el tratamiento de la inflamacion.
|
|
US5475018A
(en)
|
1993-11-30 |
1995-12-12 |
G. D. Searle & Co. |
1,5-diphenyl pyrazole compounds for treatment of inflammation
|
|
US5466823A
(en)
|
1993-11-30 |
1995-11-14 |
G.D. Searle & Co. |
Substituted pyrazolyl benzenesulfonamides
|
|
IL111785A0
(en)
*
|
1993-12-03 |
1995-01-24 |
Ferring Bv |
Dp-iv inhibitors and pharmaceutical compositions containing them
|
|
US5486534A
(en)
|
1994-07-21 |
1996-01-23 |
G. D. Searle & Co. |
3,4-substituted pyrazoles for the treatment of inflammation
|
|
EP0772606A1
(en)
|
1994-07-27 |
1997-05-14 |
G.D. SEARLE & CO. |
Substituted thiazoles for the treatment of inflammation
|
|
US5620999A
(en)
|
1994-07-28 |
1997-04-15 |
Weier; Richard M. |
Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation
|
|
US5616601A
(en)
|
1994-07-28 |
1997-04-01 |
Gd Searle & Co |
1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation
|
|
US5521213A
(en)
|
1994-08-29 |
1996-05-28 |
Merck Frosst Canada, Inc. |
Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2
|
|
US5547975A
(en)
|
1994-09-20 |
1996-08-20 |
Talley; John J. |
Benzopyranopyrazolyl derivatives for the treatment of inflammation
|
|
US5739166A
(en)
|
1994-11-29 |
1998-04-14 |
G.D. Searle & Co. |
Substituted terphenyl compounds for the treatment of inflammation
|
|
JP2636819B2
(ja)
|
1994-12-20 |
1997-07-30 |
日本たばこ産業株式会社 |
オキサゾール系複素環式芳香族化合物
|
|
JP3181190B2
(ja)
|
1994-12-20 |
2001-07-03 |
日本たばこ産業株式会社 |
オキサゾール誘導体
|
|
US5596008A
(en)
|
1995-02-10 |
1997-01-21 |
G. D. Searle & Co. |
3,4-Diaryl substituted pyridines for the treatment of inflammation
|
|
ES2183935T3
(es)
|
1995-02-13 |
2003-04-01 |
Searle & Co |
Isoxazoles sustituidos para el tratamiento de la inflamacion.
|
|
US5633272A
(en)
|
1995-02-13 |
1997-05-27 |
Talley; John J. |
Substituted isoxazoles for the treatment of inflammation
|
|
US6512121B2
(en)
|
1998-09-14 |
2003-01-28 |
G.D. Searle & Co. |
Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
|
US6515014B2
(en)
|
1995-06-02 |
2003-02-04 |
G. D. Searle & Co. |
Thiophene substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
|
CA2223154A1
(en)
|
1995-06-02 |
1996-12-05 |
G.D. Searle & Co. |
Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
|
CA2575902C
(en)
|
1995-07-21 |
2010-06-08 |
Tactical Therapeutics Inc |
Treatment and prevention of neoplasms with salts of aminoimidazole carboxamide
|
|
DE59605948D1
(de)
|
1995-07-21 |
2000-11-02 |
Nycomed Austria Gmbh Linz |
Derivate von benzosulfonamiden als hemmer des enzym cyclooxygenase ii
|
|
US5811097A
(en)
|
1995-07-25 |
1998-09-22 |
The Regents Of The University Of California |
Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling
|
|
JPH0977664A
(ja)
|
1995-09-13 |
1997-03-25 |
Yakult Honsha Co Ltd |
シクロオキシゲナーゼ−２特異的阻害剤及び抗炎症剤
|
|
US6020343A
(en)
|
1995-10-13 |
2000-02-01 |
Merck Frosst Canada, Inc. |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
|
|
US5981576A
(en)
|
1995-10-13 |
1999-11-09 |
Merck Frosst Canada, Inc. |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
|
|
US6057319A
(en)
|
1995-10-30 |
2000-05-02 |
Merck Frosst Canada & Co. |
3,4-Diaryl-2-hydroxy-2,5-dihydrofurans as prodrugs to cox-2 inhibitors
|
|
US6222048B1
(en)
|
1995-12-18 |
2001-04-24 |
Merck Frosst Canada & Co. |
Diaryl-2-(5H)-furanones as Cox-2 inhibitors
|
|
US6180651B1
(en)
|
1996-04-04 |
2001-01-30 |
Bristol-Myers Squibb |
Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics
|
|
SK285353B6
(sk)
|
1996-04-12 |
2006-11-03 |
G. D. Searle & Co. |
Substituované benzénsulfónamidy ako proliečivá COX-2 inhibítorov, farmaceutická kompozícia a spôsobich prípravy a použitia
|
|
SE9601939L
(sv)
|
1996-05-22 |
1997-04-14 |
Bo Granbom |
Bromsanordning vid manöverdon för linjär rörelse
|
|
US5883267A
(en)
|
1996-05-31 |
1999-03-16 |
Merck & Co., Inc. |
Process for making phenyl heterocycles useful as cox-2 inhibitors
|
|
GB9615867D0
(en)
|
1996-07-03 |
1996-09-11 |
Merck & Co Inc |
Process of preparing phenyl heterocycles useful as cox-2 inhibitors
|
|
US5861419A
(en)
|
1996-07-18 |
1999-01-19 |
Merck Frosst Canad, Inc. |
Substituted pyridines as selective cyclooxygenase-2 inhibitors
|
|
IL127441A
(en)
|
1996-07-18 |
2003-02-12 |
Merck Frosst Canada Inc |
Substituted pyridines, pharmaceutical compositions comprising them and their use in the preparation of anti-inflammatory medicaments or as selective cyclooxygenase-2 inhibitors
|
|
ATA16597A
(de)
|
1997-02-03 |
1998-04-15 |
Nycomed Austria Gmbh |
Neue substituierte p-sulfonylaminobenzol- sulfonsäureamide
|
|
EP0863134A1
(en)
|
1997-03-07 |
1998-09-09 |
Merck Frosst Canada Inc. |
2-(3,5-difluorophenyl)-3-(4-(methyl-sulfonyl)phenyl)-2-cyclopenten-1-one useful as an inhibitor of cyclooxygenase-2
|
|
DE69810938T2
(de)
|
1997-04-11 |
2003-11-06 |
Grelan Pharmaceutical Co., Ltd. |
Pyrazolderivate und sie enthaltende cox-inhibitoren
|
|
US6127545A
(en)
|
1997-04-18 |
2000-10-03 |
Merck & Co., Inc. |
Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors
|
|
US6130334A
(en)
|
1998-04-15 |
2000-10-10 |
Merck & Co., Inc. |
Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors
|
|
US6034256A
(en)
|
1997-04-21 |
2000-03-07 |
G.D. Searle & Co. |
Substituted benzopyran derivatives for the treatment of inflammation
|
|
US6077850A
(en)
|
1997-04-21 |
2000-06-20 |
G.D. Searle & Co. |
Substituted benzopyran analogs for the treatment of inflammation
|
|
EP0994858A1
(en)
|
1997-06-30 |
2000-04-26 |
Ortho-McNeil Pharmaceutical, Inc. |
2-substituted imidazoles useful in the treatment of inflammatory diseases
|
|
AP9801302A0
(en)
|
1997-07-23 |
2000-01-23 |
Pfizer |
Indole compounds as anti-inflammatory/analgesic agents..
|
|
DK0999825T3
(da)
|
1997-07-29 |
2004-02-09 |
Alcon Lab Inc |
Oftalmiske sammensætninger indeholdende galactomannanpolymerer og borater
|
|
US6307047B1
(en)
|
1997-08-22 |
2001-10-23 |
Abbott Laboratories |
Prostaglandin endoperoxide H synthase biosynthesis inhibitors
|
|
PT1005460E
(pt)
|
1997-08-22 |
2006-07-31 |
Abbott Lab |
Biossintese de inibidores de prostaglandina-endoperoxido h-sintase
|
|
CA2299300C
(en)
|
1997-08-22 |
2007-04-17 |
Abbott Laboratories |
Arylpyridazinones as prostaglandin endoperoxide h synthase bisoynthesis inhibitors
|
|
WO2000024719A1
(en)
|
1998-10-27 |
2000-05-04 |
Abbott Laboratories |
Prostaglandin endoperoxide h synthase biosynthesis inhibitors
|
|
CO4960662A1
(es)
|
1997-08-28 |
2000-09-25 |
Novartis Ag |
Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados
|
|
ES2256817T3
(es)
|
1997-09-05 |
2006-07-16 |
Glaxo Group Limited |
Composiciones farmaceuticas que comprenden derivados de 2,3-diaril-pirazolo(1,5-b)piridazina.
|
|
US5925769A
(en)
|
1997-09-09 |
1999-07-20 |
Ortho Pharmaceutical, Corp. |
Acetylenic 1,5-diarylpyrazoles as antiinflammatory agents
|
|
US6046217A
(en)
|
1997-09-12 |
2000-04-04 |
Merck Frosst Canada & Co. |
2,3,5-trisubstituted pyridines as inhibitors of cyclooxygenase-2
|
|
US6140515A
(en)
|
1997-09-24 |
2000-10-31 |
Merck & Co., Inc. |
Process of making 3-aryloxy, 4-aryl furan-2-ones useful as inhibitors of COX-2
|
|
US6040450A
(en)
|
1997-09-25 |
2000-03-21 |
Merck & Co., Inc. |
Process for making diaryl pyridines useful as cox-2-inhibitors
|
|
US6080876A
(en)
|
1997-10-29 |
2000-06-27 |
Merck & Co., Inc. |
Process for making phenyl heterocycles useful as COX-2 inhibitors
|
|
US6133292A
(en)
|
1997-10-30 |
2000-10-17 |
Merck Frosst Canada & Co. |
Diaryl-5-alkyl-5-methyl-2-(5H)-furanones as selective cyclooxygenase-2-inhibitors
|
|
US6110973A
(en)
|
1998-01-29 |
2000-08-29 |
Sepracor |
Methods for treating obesity and weight gain using optically pure (-)-bupropion
|
|
AU766219B2
(en)
*
|
1998-02-02 |
2003-10-09 |
1149336 Ontario Inc. |
Method of regulating glucose metabolism, and reagents related thereto
|
|
US20010031275A1
(en)
|
1998-02-09 |
2001-10-18 |
Forse R Armour |
Sesamol inhibitor of delta-5-desaturase activity and uses therefor
|
|
JP3256513B2
(ja)
|
1998-02-11 |
2002-02-12 |
ファイザー製薬株式会社 |
ベンゾイミダゾールシクロオキシゲナーゼ−２阻害剤
|
|
US5994379A
(en)
|
1998-02-13 |
1999-11-30 |
Merck Frosst Canada, Inc. |
Bisaryl COX-2 inhibiting compounds, compositions and methods of use
|
|
EP1085845A2
(en)
|
1998-06-08 |
2001-03-28 |
Advanced Medicine, Inc. |
Multibinding inhibitors of cyclooxygenase-2
|
|
KR100295206B1
(ko)
|
1998-08-22 |
2001-07-12 |
서경배 |
디아릴벤조피란유도체및이를함유하는시클로옥시게네이즈-2저해제조성물
|
|
TW587079B
(en)
|
1998-09-25 |
2004-05-11 |
Almirall Prodesfarma Ag |
2-phenylpyran-4-one derivatives
|
|
US6077869A
(en)
|
1998-10-29 |
2000-06-20 |
Ortho-Mcneil Pharmaceutical, Inc. |
Aryl phenylhydrazides as selective COX-2 inhibitors for treatment of inflammation
|
|
JP2002528498A
(ja)
|
1998-11-02 |
2002-09-03 |
メルク エンド カムパニー インコーポレーテッド |
片頭痛の治療方法及び医薬組成物
|
|
WO2000028997A1
(en)
|
1998-11-12 |
2000-05-25 |
Analytica Ltd |
Phospholipase inhibitors for the treatment of cancer
|
|
US6682736B1
(en)
|
1998-12-23 |
2004-01-27 |
Abgenix, Inc. |
Human monoclonal antibodies to CTLA-4
|
|
US6498166B1
(en)
|
1999-02-27 |
2002-12-24 |
Smithkline Beecham Corporation |
Pyrazolopyridines
|
|
GB9906714D0
(en)
*
|
1999-03-23 |
1999-05-19 |
Ferring Bv |
Compositions for improving fertility
|
|
DZ3265A1
(fr)
|
1999-04-14 |
2000-10-19 |
Pacific Corp |
Derives de 4,5-diaryl-3(2h)-furanone comme inhibiteurs de cyclo-oxygenase-2
|
|
US6376519B1
(en)
|
1999-06-16 |
2002-04-23 |
Temple University-Of The Commonwealth Of Higher Education |
1-(4-sulfamylaryl)-3-substituted-5-aryl-2-pyrazolines and inhibitors of cyclooxygenase-2
|
|
MXPA00006605A
(es)
|
1999-07-02 |
2004-12-09 |
Pfizer |
Compuestos de carbonil-indol biciclicos como agentes antiinflamatorios/analgesicos.
|
|
US6077868A
(en)
|
1999-07-20 |
2000-06-20 |
Wisconsin Alumni Research Foundation |
Selective inhibition of cyclooxygenase-2
|
|
US6472416B1
(en)
|
1999-08-27 |
2002-10-29 |
Abbott Laboratories |
Sulfonylphenylpyrazole compounds useful as COX-2 inhibitors
|
|
US6306890B1
(en)
|
1999-08-30 |
2001-10-23 |
Vanderbilt University |
Esters derived from indolealkanols and novel amides derived from indolealkylamides that are selective COX-2 inhibitors
|
|
US8889112B2
(en)
|
1999-09-16 |
2014-11-18 |
Ocularis Pharma, Llc |
Ophthalmic formulations including selective alpha 1 antagonists
|
|
US6083969A
(en)
|
1999-10-20 |
2000-07-04 |
Ortho-Mcneil Pharaceutical, Inc. |
1,3- and 2,3-diarylcycloalkano and cycloalkeno pyrazoles as selective inhibitors of cyclooxygenase-2 and antiinflammatory agents
|
|
US6395767B2
(en)
*
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
|
US6465509B2
(en)
|
2000-06-30 |
2002-10-15 |
Merck Frosst Canada & Co. |
Pyrones as inhibitors of cyclooxygenase-2
|
|
PE20020351A1
(es)
|
2000-09-11 |
2002-06-14 |
Novartis Ag |
Composiciones farmaceuticas que comprenden acido 5-metil-2-(2'-cloro-6'-fluoroanilino)fenilacetico como inhibidor de la ciclooxigenasa-2
|
|
US6359182B1
(en)
|
2000-10-26 |
2002-03-19 |
Duke University |
C-nitroso compounds and use thereof
|
|
US6573287B2
(en)
|
2001-04-12 |
2003-06-03 |
Bristo-Myers Squibb Company |
2,1-oxazoline and 1,2-pyrazoline-based inhibitors of dipeptidyl peptidase IV and method
|
|
US20030105144A1
(en)
|
2001-04-17 |
2003-06-05 |
Ping Gao |
Stabilized oral pharmaceutical composition
|
|
KR100809489B1
(ko)
|
2001-10-10 |
2008-03-03 |
씨제이제일제당 (주) |
사이클로옥시게나제-2의 저해제로서 선택성이 뛰어난4'-메탄설포닐-비페닐 유도체
|
|
KR100810468B1
(ko)
|
2001-10-10 |
2008-03-07 |
씨제이제일제당 (주) |
사이클로옥시게나제-2의 저해제로서 선택성이 뛰어난1ｈ-인돌 유도체
|
|
WO2003037351A1
(en)
|
2001-11-02 |
2003-05-08 |
Pfizer Products Inc. |
Heterocyclo-alkylsulfonyl pyrazoles and their use as cox-2 inhibitors
|
|
US6555563B1
(en)
|
2001-11-16 |
2003-04-29 |
Medinox, Inc. |
Heteroaryl substituted amidinyl and imidazolyl compounds and methods employing same for the treatment of inflammation
|
|
EP1469873A4
(en)
*
|
2001-11-26 |
2007-10-03 |
Tufts College |
PEPTIDOMIMETIC INHIBITORS FROM BEHIND PROLIN SPLENDING ENZYMES
|
|
US20030165588A1
(en)
|
2002-03-01 |
2003-09-04 |
Unigen Pharmaceuticals, Inc. |
Identification of free-B-ring flavonoids as potent COX-2 inhibitors
|
|
ATE368647T1
(de)
*
|
2002-09-19 |
2007-08-15 |
Abbott Lab |
Pharmazeutische zusammensetzung und ihre verwendung als inhibitoren von der dipeptidyl peptidase iv (dpp-iv)
|
|
CN1753912B
(zh)
|
2002-12-23 |
2011-11-02 |
惠氏公司 |
抗pd-1抗体及其用途
|
|
US6933289B2
(en)
|
2003-07-01 |
2005-08-23 |
Allergan, Inc. |
Inhibition of irritating side effects associated with use of a topical ophthalmic medication
|
|
US6995183B2
(en)
*
|
2003-08-01 |
2006-02-07 |
Bristol Myers Squibb Company |
Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
CA2534484A1
(en)
|
2003-08-07 |
2005-02-17 |
Allergan, Inc. |
Compositions for delivery of therapeutics into the eyes and methods for making and using same
|
|
US20050059744A1
(en)
|
2003-09-12 |
2005-03-17 |
Allergan, Inc. |
Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions
|
|
US20050203027A1
(en)
|
2004-02-23 |
2005-09-15 |
Trustees Of Tufts College |
Inhibitors of dipeptidylpeptidase IV
|
|
AU2006239929B2
(en)
*
|
2005-04-22 |
2011-11-03 |
Alantos Pharmaceuticals Holding, Inc. |
Dipeptidyl peptidase-IV inhibitors
|
|
RU2494107C2
(ru)
|
2005-05-09 |
2013-09-27 |
Оно Фармасьютикал Ко., Лтд. |
Моноклональные антитела человека к белку программируемой смерти 1 (pd-1) и способы лечения рака с использованием анти-pd-1-антител самостоятельно или в комбинации с другими иммунотерапевтическими средствами
|
|
CN104356236B
(zh)
|
2005-07-01 |
2020-07-03 |
E.R.施贵宝&圣斯有限责任公司 |
抗程序性死亡配体1(pd-l1)的人单克隆抗体
|
|
WO2007100374A2
(en)
*
|
2005-12-19 |
2007-09-07 |
Trustees Of Tufts College |
Soft protease inhibitors and pro-soft forms thereof
|
|
WO2007123686A2
(en)
|
2006-03-31 |
2007-11-01 |
Point Therapeutics, Inc. |
Dpp inhibitors and uses thereof
|
|
WO2007117419A2
(en)
|
2006-03-31 |
2007-10-18 |
Dara Biosciences, Inc. |
Methods and compositions relating to post-prolyl cleaving enzyme inhibitors
|
|
WO2007127204A2
(en)
|
2006-04-24 |
2007-11-08 |
Dara Biosciences, Inc. |
Methods and compositions relating to immunostimulation
|
|
HRP20131167T1
(hr)
|
2007-06-18 |
2014-01-03 |
Merck Sharp & Dohme B.V. |
Antitijela za humani receptor programirane smrti pd-1
|
|
PT2242773T
(pt)
|
2008-02-11 |
2017-09-15 |
Cure Tech Ltd |
Anticorpos monoclonais para o tratamento de tumores
|
|
WO2009114335A2
(en)
|
2008-03-12 |
2009-09-17 |
Merck & Co., Inc. |
Pd-1 binding proteins
|
|
WO2010098788A2
(en)
|
2008-08-25 |
2010-09-02 |
Amplimmune, Inc. |
Pd-i antagonists and methods for treating infectious disease
|
|
CN102203132A
(zh)
|
2008-08-25 |
2011-09-28 |
安普利穆尼股份有限公司 |
Pd-1拮抗剂的组合物和使用方法
|
|
AU2009333580B2
(en)
|
2008-12-09 |
2016-07-07 |
Genentech, Inc. |
Anti-PD-L1 antibodies and their use to enhance T-cell function
|
|
WO2010089411A2
(en)
|
2009-02-09 |
2010-08-12 |
Universite De La Mediterranee |
Pd-1 antibodies and pd-l1 antibodies and uses thereof
|
|
SG174504A1
(en)
*
|
2009-03-27 |
2011-10-28 |
Bristol Myers Squibb Co |
Methods for preventing major adverse cardiovascular events with dpp-iv inhibitors
|
|
WO2011066342A2
(en)
|
2009-11-24 |
2011-06-03 |
Amplimmune, Inc. |
Simultaneous inhibition of pd-l1/pd-l2
|
|
US8518945B2
(en)
*
|
2010-03-22 |
2013-08-27 |
Hoffmann-La Roche Inc. |
Pyrrolopyrazine kinase inhibitors
|
|
CN103732238A
(zh)
|
2011-06-08 |
2014-04-16 |
奥瑞基尼探索技术有限公司 |
用于免疫调节的治疗性化合物
|
|
CN104039952A
(zh)
|
2011-11-22 |
2014-09-10 |
塔夫茨大学信托人 |
用于树突状细胞癌症疫苗的小分子增强剂
|
|
WO2013132317A1
(en)
|
2012-03-07 |
2013-09-12 |
Aurigene Discovery Technologies Limited |
Peptidomimetic compounds as immunomodulators
|
|
WO2014022636A1
(en)
|
2012-08-02 |
2014-02-06 |
Trustees Of Tufts College |
Broad spectrum inhibitors of the post proline cleaving enzymes for treatment of hepatitis c virus infections
|
|
CN104003922A
(zh)
|
2013-02-27 |
2014-08-27 |
中国药科大学 |
取代吡咯烷类衍生物及其制备方法和在医药上的用途
|
|
US9308236B2
(en)
|
2013-03-15 |
2016-04-12 |
Bristol-Myers Squibb Company |
Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
|
|
SG10201900002QA
(en)
*
|
2014-01-24 |
2019-02-27 |
Dana Farber Cancer Institue Inc |
Antibody molecules to pd-1 and uses thereof
|
|
AU2015327868A1
(en)
|
2014-10-03 |
2017-04-20 |
Novartis Ag |
Combination therapies
|
|
CN116059219A
(zh)
*
|
2015-07-16 |
2023-05-05 |
比奥克斯塞尔医疗股份有限公司 |
一种使用免疫调节治疗癌症的新颖方法
|
|
WO2018049014A1
(en)
|
2016-09-07 |
2018-03-15 |
Trustees Of Tufts College |
Dash inhibitors, and uses related thereto
|
|
WO2018187698A2
(en)
|
2017-04-07 |
2018-10-11 |
Trustees Of Tufts College |
Combination therapies using caspase-1 dependent anticancer agents and pge2 antagonists
|
|
US11559537B2
(en)
|
2017-04-07 |
2023-01-24 |
Trustees Of Tufts College |
Combination therapies using caspase-1 dependent anticancer agents and PGE2 antagonists
|
|
CA3101640A1
(en)
|
2018-06-04 |
2019-12-12 |
Trustees Of Tufts College |
Tumor microenvironment-activated drug-binder conjugates, and uses related thereto
|