JP2019528435A5 - - Google Patents
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- Publication number
- JP2019528435A5 JP2019528435A5 JP2019503570A JP2019503570A JP2019528435A5 JP 2019528435 A5 JP2019528435 A5 JP 2019528435A5 JP 2019503570 A JP2019503570 A JP 2019503570A JP 2019503570 A JP2019503570 A JP 2019503570A JP 2019528435 A5 JP2019528435 A5 JP 2019528435A5
- Authority
- JP
- Japan
- Prior art keywords
- sample
- fluid sample
- support
- sample support
- gas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012530 fluid Substances 0.000 claims 26
- 238000001493 electron microscopy Methods 0.000 claims 13
- 238000000034 method Methods 0.000 claims 3
- 238000001816 cooling Methods 0.000 claims 2
- 238000001704 evaporation Methods 0.000 claims 2
- 230000008020 evaporation Effects 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 239000012491 analyte Substances 0.000 claims 1
- 230000009849 deactivation Effects 0.000 claims 1
- 238000010494 dissociation reaction Methods 0.000 claims 1
- 230000005593 dissociations Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1613173.2A GB201613173D0 (en) | 2016-07-29 | 2016-07-29 | Electron microscopy |
| GB1613173.2 | 2016-07-29 | ||
| PCT/EP2017/069240 WO2018020036A1 (en) | 2016-07-29 | 2017-07-28 | Electron microscopy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019528435A JP2019528435A (ja) | 2019-10-10 |
| JP2019528435A5 true JP2019528435A5 (enExample) | 2020-09-03 |
| JP6997757B2 JP6997757B2 (ja) | 2022-02-04 |
Family
ID=56936668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019503570A Active JP6997757B2 (ja) | 2016-07-29 | 2017-07-28 | 電子顕微鏡法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11067486B2 (enExample) |
| EP (1) | EP3491360B1 (enExample) |
| JP (1) | JP6997757B2 (enExample) |
| CN (1) | CN109891208A (enExample) |
| AU (1) | AU2017302126B2 (enExample) |
| CA (1) | CA3032234C (enExample) |
| DK (1) | DK3491360T3 (enExample) |
| ES (1) | ES3026360T3 (enExample) |
| GB (1) | GB201613173D0 (enExample) |
| WO (1) | WO2018020036A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3647763B1 (en) | 2018-10-29 | 2021-07-14 | FEI Company | A method of preparing a biological sample for study in an analysis device |
| CN111389478B (zh) * | 2020-03-23 | 2023-07-25 | 西安医学院 | 一种组织切片的实验处理装置及其使用方法 |
| GB2593491A (en) * | 2020-03-24 | 2021-09-29 | Res & Innovation Uk | Electron microscopy support |
| EP4109069A1 (en) | 2021-06-25 | 2022-12-28 | FEI Company | Blotting material with profiled region, method of manufacturing same, and uses thereof |
| NL2033291B1 (en) | 2022-10-12 | 2024-04-26 | Academisch Ziekenhuis Leiden | Device and Method for Cryogenic Electron Microscopy Sample Preparation |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59109840A (ja) | 1982-12-16 | 1984-06-25 | Hitachi Koki Co Ltd | 走査形電子顕微鏡用生物試料の前処理方法 |
| US7112790B1 (en) * | 2003-08-13 | 2006-09-26 | Cypress Semiconductor Corp. | Method to prepare TEM samples |
| JP2007163447A (ja) * | 2005-12-09 | 2007-06-28 | Lee Bing Huan | 電子顕微鏡用の超薄液体制御板 |
| JP4891830B2 (ja) * | 2007-04-18 | 2012-03-07 | 日本電子株式会社 | 電子顕微鏡用試料ホルダおよび観察方法 |
| WO2009065585A2 (en) * | 2007-11-20 | 2009-05-28 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Ultra-rapid freezing device and method |
| GB0724736D0 (en) * | 2007-12-19 | 2008-01-30 | Oxford Nanolabs Ltd | Formation of layers of amphiphilic molecules |
| GB2461708A (en) * | 2008-07-08 | 2010-01-13 | Silson Ltd | Sample holder |
| JP2010054272A (ja) | 2008-08-27 | 2010-03-11 | National Institute Of Advanced Industrial Science & Technology | スピン偏極走査電子顕微鏡 |
| AT507079B1 (de) * | 2009-01-22 | 2010-02-15 | Leica Mikrosysteme Gmbh | Vorrichtung und verfahren zum präparieren von proben |
| JP5550262B2 (ja) * | 2009-05-29 | 2014-07-16 | キヤノン株式会社 | 試料観察システム及び試料観察方法 |
| US9312095B2 (en) * | 2010-03-24 | 2016-04-12 | Brown University | Method and system for automating sample preparation for microfluidic cryo TEM |
| GB201118282D0 (en) | 2011-10-21 | 2011-12-07 | Cancer Rec Tech Ltd | Sample slide preparation method and device |
| JP5930922B2 (ja) * | 2012-09-14 | 2016-06-08 | 株式会社日立ハイテクノロジーズ | 荷電粒子線装置及び試料観察方法 |
| JP6239246B2 (ja) * | 2013-03-13 | 2017-11-29 | 株式会社日立ハイテクノロジーズ | 荷電粒子線装置、試料観察方法、試料台、観察システム、および発光部材 |
| CA2919961C (en) * | 2013-08-13 | 2023-10-10 | Medical Research Council | Electron microscopy sample support comprising porous metal foil |
| GB201318463D0 (en) * | 2013-08-13 | 2013-12-04 | Medical Res Council | Graphene Modification |
| EP2853847B1 (en) * | 2013-09-30 | 2016-02-03 | Fei Company | Preparation of cryogenic sample for charged-particle microscopy |
| CA2932803C (en) | 2013-12-13 | 2020-09-08 | Ventana Medical Systems, Inc. | Thermal management in the context of automated histological processing of biological specimens and associated technology |
| GB2537579A (en) | 2014-11-07 | 2016-10-26 | Linkam Scient Instr Ltd | Microscopic sample preparation |
| EP4215898A1 (en) * | 2015-04-20 | 2023-07-26 | Ventana Medical Systems, Inc. | Inkjet deposition of reagents for histological samples |
| DK3260839T3 (da) * | 2016-06-22 | 2021-04-19 | Univ Maastricht | Fremgangsmåde til forberedelse af prøver til billeddannelses- eller diffraktionseksperimenter under kyrogene betingelser |
| EP3647763B1 (en) * | 2018-10-29 | 2021-07-14 | FEI Company | A method of preparing a biological sample for study in an analysis device |
-
2016
- 2016-07-29 GB GBGB1613173.2A patent/GB201613173D0/en not_active Ceased
-
2017
- 2017-07-28 AU AU2017302126A patent/AU2017302126B2/en active Active
- 2017-07-28 ES ES17745722T patent/ES3026360T3/es active Active
- 2017-07-28 CA CA3032234A patent/CA3032234C/en active Active
- 2017-07-28 JP JP2019503570A patent/JP6997757B2/ja active Active
- 2017-07-28 EP EP17745722.3A patent/EP3491360B1/en active Active
- 2017-07-28 WO PCT/EP2017/069240 patent/WO2018020036A1/en not_active Ceased
- 2017-07-28 DK DK17745722.3T patent/DK3491360T3/da active
- 2017-07-28 CN CN201780047251.7A patent/CN109891208A/zh active Pending
- 2017-07-28 US US16/320,961 patent/US11067486B2/en active Active
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