JP2019525898A5 - - Google Patents
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- Publication number
- JP2019525898A5 JP2019525898A5 JP2018564945A JP2018564945A JP2019525898A5 JP 2019525898 A5 JP2019525898 A5 JP 2019525898A5 JP 2018564945 A JP2018564945 A JP 2018564945A JP 2018564945 A JP2018564945 A JP 2018564945A JP 2019525898 A5 JP2019525898 A5 JP 2019525898A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- polypeptide
- hla
- composition
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16173986 | 2016-06-10 | ||
| EP16173986.7 | 2016-06-10 | ||
| EP16173970.1 | 2016-06-10 | ||
| EP16173970 | 2016-06-10 | ||
| PCT/EP2017/064323 WO2017212072A1 (en) | 2016-06-10 | 2017-06-12 | Human leukocyte antigen restricted gamma delta t cell receptors and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019525898A JP2019525898A (ja) | 2019-09-12 |
| JP2019525898A5 true JP2019525898A5 (enExample) | 2020-07-27 |
Family
ID=59101448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018564945A Ceased JP2019525898A (ja) | 2016-06-10 | 2017-06-12 | ヒト白血球抗原拘束ガンマデルタt細胞受容体及びその使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US11596654B2 (enExample) |
| EP (4) | EP3469362B1 (enExample) |
| JP (1) | JP2019525898A (enExample) |
| KR (1) | KR102489954B1 (enExample) |
| CN (1) | CN109997041B (enExample) |
| CA (2) | CA3027124A1 (enExample) |
| ES (1) | ES2987986T3 (enExample) |
| HU (1) | HUE068936T2 (enExample) |
| PL (1) | PL3469361T3 (enExample) |
| WO (2) | WO2017212072A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6403663B2 (ja) | 2012-03-28 | 2018-10-10 | ガデタ・ベー・フェー | コンビナトリアルガンマ9デルタ2t細胞レセプター鎖交換 |
| PL3469361T3 (pl) | 2016-06-10 | 2025-02-03 | Gadeta B.V. | Nowy sposób identyfikacji łańcuchów receptora limfocytu t delta (lub limfocytu t gamma) lub części tych łańcuchów, które pośredniczą w odpowiedzi przeciwnowotworowej lub przeciwzakaźnej |
| CA3063807A1 (en) | 2017-05-18 | 2018-11-22 | Umc Utrecht Holding B.V. | Compositions and methods for cell targeting therapies |
| WO2019156566A1 (en) * | 2018-02-12 | 2019-08-15 | Umc Utrecht Holding B.V. | Bispecific molecules comprising gamma-delta tcr and t-cell or nk cell binding domain |
| MX2020011158A (es) * | 2018-04-23 | 2021-01-08 | Commscope Technologies Llc | Recinto de telecomunicaciones con sistema de bloqueo modular. |
| WO2019219979A1 (en) | 2018-05-18 | 2019-11-21 | Umc Utrecht Holding B.V. | Compositions and methods for cell targeting therapies |
| UY38427A (es) | 2018-10-26 | 2020-05-29 | Novartis Ag | Métodos y composiciones para terapia con células oculares |
| US20230348852A1 (en) | 2020-04-27 | 2023-11-02 | Novartis Ag | Methods and compositions for ocular cell therapy |
| WO2021236963A1 (en) * | 2020-05-20 | 2021-11-25 | Chan Zuckerberg Biohub, Inc. | Total rna profiling of biological samples and single cells |
| WO2022136681A1 (en) | 2020-12-23 | 2022-06-30 | Gadeta B.V. | Chimeric, transmembrane proteins with bidirectional signalling activity |
| CN113046320B (zh) * | 2021-02-19 | 2023-04-14 | 中国医学科学院基础医学研究所 | 胞外段为Vδ1(GTM)Vγ4的CAR分子及表达该分子的CAR-T细胞及其用途 |
| EP4059955A1 (en) | 2021-03-19 | 2022-09-21 | Medizinische Hochschule Hannover | Hla-dr-specific gamma delta tcr constructs and use thereof |
| WO2022214707A1 (en) | 2021-04-09 | 2022-10-13 | Gadeta B.V. | Cellular reporter and methods of using the same |
| WO2022258606A1 (en) | 2021-06-07 | 2022-12-15 | Gadeta B.V. | Delta T-cell or Gamma T-cell receptor chains or parts thereof that mediate an anti-tumour or anti-infective response |
| AU2022310862A1 (en) | 2021-07-14 | 2024-02-01 | Regeneron Pharmaceuticals, Inc. | Engineered t cell receptors fused to binding domains from antibodies |
| IL316032A (en) | 2022-04-08 | 2024-11-01 | Regeneron Pharma | Multicomponent receptor and signaling complexes |
| WO2023227594A1 (en) | 2022-05-24 | 2023-11-30 | Gadeta Bv | Novel deltat-cell receptor chains, gammat-cell receptor chains, or parts thereof |
| WO2023237541A1 (en) | 2022-06-07 | 2023-12-14 | Gadeta B.V. | Delta t-cell or gamma t-cell receptor chains or parts thereof that mediate an anti-tumour or anti-infective response |
| US20260014199A1 (en) | 2022-06-17 | 2026-01-15 | Gadeta B.V. | Modified immune cells |
| US20240075068A1 (en) * | 2022-07-15 | 2024-03-07 | Gadeta B.V. | Novel soluble gamma T-cell (or soluble delta T-cell) receptor chains (or soluble gammadelta T-cell receptors) or fragments thereof that mediate an anti-tumour or an anti-infective response |
| US20240043496A1 (en) * | 2022-07-26 | 2024-02-08 | Gadeta B.V. | Delta t-cell or gamma receptor chains or parts thereof for treating ovarian cancer |
| WO2025231488A1 (en) * | 2024-05-03 | 2025-11-06 | Northwestern University | Gamma-delta t cell receptors for cancer therapy |
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| FR901228A (fr) | 1943-01-16 | 1945-07-20 | Deutsche Edelstahlwerke Ag | Système d'aimant à entrefer annulaire |
| US5260223A (en) * | 1986-07-03 | 1993-11-09 | President & Fellows Of Harvard College | Methods for detection of human gamma, γ T cell receptor |
| CA2018248A1 (en) | 1989-06-07 | 1990-12-07 | Clyde W. Shearman | Monoclonal antibodies against the human alpha/beta t-cell receptor, their production and use |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| US5350674A (en) | 1992-09-04 | 1994-09-27 | Becton, Dickinson And Company | Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof |
| FR2698880B1 (fr) | 1992-11-25 | 1995-02-24 | Inst Nat Sante Rech Med | Procédé de production de récepteurs T solubles, produits ainsi obtenus et leur utilisation dans des compositions diagnostiques ou thérapeutiques. |
| US5962271A (en) | 1996-01-03 | 1999-10-05 | Cloutech Laboratories, Inc. | Methods and compositions for generating full-length cDNA having arbitrary nucleotide sequence at the 3'-end |
| US6207455B1 (en) | 1997-05-01 | 2001-03-27 | Lung-Ji Chang | Lentiviral vectors |
| EP0981636B1 (en) | 1997-05-13 | 2005-03-23 | University Of North Carolina At Chapel Hill | Lentivirus-based gene transfer vectors |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| US6218181B1 (en) | 1998-03-18 | 2001-04-17 | The Salk Institute For Biological Studies | Retroviral packaging cell line |
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| BR9910253A (pt) * | 1998-05-19 | 2002-09-17 | Avidex Ltd | Receptor de célula t solúvel |
| DE19909769A1 (de) | 1999-03-05 | 2000-09-07 | Bundesrepublik Deutschland Let | Von SIVagm abgeleitete lentivirale Vektoren, Verfahren zu ihrer Herstellung und ihre Verwendung zur Genübertragung in Säugerzellen |
| JP2001332430A (ja) | 2000-05-22 | 2001-11-30 | Murata Mfg Co Ltd | トランス |
| WO2002024718A1 (en) | 2000-09-19 | 2002-03-28 | Diadexus, Inc. | Compositions and methods relating to prostate specific genes and proteins |
| KR100669065B1 (ko) * | 2001-04-03 | 2007-01-15 | 다카라 바이오 가부시키가이샤 | 세포상해성 t 림프구 |
| US6905827B2 (en) * | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
| US7745140B2 (en) | 2002-01-03 | 2010-06-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool |
| AU2003235593A1 (en) | 2002-01-10 | 2003-07-30 | National Jewish Medical And Research Center | USE OF SOLUBLE GammaDelta T CELL RECEPTORS FOR REGULATING T CELL FUNCTION |
| AU2003259913A1 (en) | 2002-08-19 | 2004-03-03 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| WO2005051988A2 (en) * | 2003-03-03 | 2005-06-09 | Genentech, Inc. | Compositions and methods for the treatment of systemic lupus erythematosis |
| US7892745B2 (en) * | 2003-04-24 | 2011-02-22 | Xdx, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| WO2005005631A1 (ja) | 2003-07-11 | 2005-01-20 | Dainippon Sumitomo Pharma Co., Ltd. | リビン由来のhla-a24結合性癌抗原ペプチド |
| WO2005019258A2 (en) | 2003-08-11 | 2005-03-03 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| US20050249743A1 (en) * | 2004-01-12 | 2005-11-10 | Thierry Boon-Falleur | Isolated peptides which bind to HLA-A24 molecules and uses thereof |
| US20050255105A1 (en) | 2004-03-22 | 2005-11-17 | The Board Of Trustees Of The Leland Stanford Junior University | Severe myelin deficits induced by self-reactive gamma delta T cells |
| CA2568344C (en) | 2004-05-27 | 2016-01-19 | The Trustees Of The University Of Pennsylvania | Novel artificial antigen presenting cells and uses therefor |
| WO2006026051A2 (en) * | 2004-08-03 | 2006-03-09 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Selections of genes and methods of using the same for diagnosis, prognosis and for targeting the therapy of neuroblastoma |
| GB0425732D0 (en) | 2004-11-23 | 2004-12-22 | Avidex Ltd | Gamma-delta t cell receptors |
| GB0506760D0 (en) * | 2005-04-01 | 2005-05-11 | Avidex Ltd | High affinity HIV TCRS |
| EP1941028A2 (en) | 2005-08-08 | 2008-07-09 | Fondazione Centro San Raffaele Del Monte Tabor | Use of common gamma chain cytokines for the visualization, isolation and genetic modification of memory t lymphocytes. |
| EP1806358B1 (en) * | 2005-09-05 | 2010-03-17 | Immatics Biotechnologies GmbH | Tumor-associated peptides binding promiscuously to human leukocyte antigen (HLA) class II molecules |
| EP1945246A4 (en) * | 2005-09-22 | 2009-03-11 | Irun R Cohen | IMMUNOGENIC FRAGMENTS OF CONSTANT DOMAINS OF THE T CELL RECEPTOR AND PEPTIDES DERIVED THEREFROM |
| US20080131415A1 (en) | 2006-11-30 | 2008-06-05 | Riddell Stanley R | Adoptive transfer of cd8 + t cell clones derived from central memory cells |
| EP2288700B1 (en) | 2008-05-09 | 2017-02-08 | Agency for Science, Technology And Research | Hbv epitope reactive exogenous t cell receptor (tcr) and uses thereof |
| CN102272153B (zh) * | 2008-11-24 | 2015-04-15 | 德国慕尼黑亥姆霍兹研究中心健康和环境有限公司 | 高亲和力t细胞受体及其应用 |
| WO2010087335A1 (ja) | 2009-01-27 | 2010-08-05 | 学校法人産業医科大学 | T細胞抗原受容体遺伝子、受容体α鎖及びβ鎖発現用ベクター並びに細胞障害性T細胞 |
| ES2743507T3 (es) | 2009-11-02 | 2020-02-19 | Univ Emory | Inmunoterapia resistente a fármaco para el tratamiento de un cáncer |
| CN102453701B (zh) | 2010-10-26 | 2014-08-13 | 中国医学科学院基础医学研究所 | 基因修饰CDR3δ移植型γδT淋巴细胞及其抑癌用途 |
| US20150353643A1 (en) | 2013-09-24 | 2015-12-10 | Universite De La Mediterranee - Aix-Marseille Ii | Anti-cd277 antibodies and uses thereof |
| EP2686417B1 (de) | 2011-03-17 | 2016-06-08 | Miltenyi Biotec GmbH | Tcralpha/beta-depletierte zellpräparationen |
| CN102532269B (zh) * | 2011-05-16 | 2014-07-09 | 中国医学科学院基础医学研究所 | γδT淋巴细胞中δ1链互补决定域3的优势序列及其TCR受体转染细胞与应用 |
| PT2710123T (pt) | 2011-05-19 | 2017-10-13 | Inst De Medicina Molecular | Linha celular de linfócitos compreendendo células t gama-delta, método de composição e produção resultante dos mesmos |
| PH12014500247A1 (en) | 2011-07-29 | 2014-03-24 | Univ Pennsylvania | Switch costimulatory receptors |
| JP6403663B2 (ja) * | 2012-03-28 | 2018-10-10 | ガデタ・ベー・フェー | コンビナトリアルガンマ9デルタ2t細胞レセプター鎖交換 |
| EP3763810A3 (en) | 2012-10-10 | 2021-07-14 | Sangamo Therapeutics, Inc. | T cell modifying compounds and uses thereof |
| WO2014179202A1 (en) * | 2013-05-02 | 2014-11-06 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for diagnosis of celiac disease |
| WO2015063069A1 (en) * | 2013-10-28 | 2015-05-07 | Benjamin Felder | Chimeric antigen receptors with antigen binding domains derived from gamma delta t cell receptors |
| JP6164759B2 (ja) * | 2013-11-21 | 2017-07-19 | Repertoire Genesis株式会社 | T細胞受容体およびb細胞受容体レパトアの解析システムならびにその治療および診断への利用 |
| CN106459915A (zh) | 2014-02-04 | 2017-02-22 | 凯德药业公司 | 用于治疗b细胞恶性肿瘤和其它癌症的自体t细胞的生产方法及其组合物 |
| SG11201609370QA (en) * | 2014-05-13 | 2016-12-29 | Chugai Pharmaceutical Co Ltd | T cell-redirected antigen-binding molecule for cells having immunosuppression function |
| WO2016195086A1 (ja) | 2015-06-05 | 2016-12-08 | 医療法人社団 滉志会 | アレルギー性疾患の治療薬 |
| ES2710618T3 (es) | 2015-08-06 | 2019-04-26 | Agency Science Tech & Res | Anticuerpos frente a IL2R-Beta/cadena gamma común |
| AU2016318961A1 (en) | 2015-09-11 | 2018-03-22 | Agenus Inc. | Engineered host cells and methods of use thereof |
| CN105296431B (zh) * | 2015-11-26 | 2018-10-09 | 北京佳德和细胞治疗技术有限公司 | 肿瘤结合特异性γδTCR基因修饰的αβT细胞及其抑癌用途 |
| US12297427B2 (en) | 2015-12-04 | 2025-05-13 | St. Jude Children's Research Hospital, Inc. | Cloning and expression system for T-cell receptors |
| MX2018013864A (es) | 2016-05-12 | 2019-06-10 | Adicet Bio Inc | Métodos para la expansión selectiva de poblaciones de células t gama y composicicones de estas. |
| US10222369B2 (en) | 2016-05-17 | 2019-03-05 | Chimera Bioengineering, Inc. | Methods for making novel antigen binding domains |
| PL3469361T3 (pl) | 2016-06-10 | 2025-02-03 | Gadeta B.V. | Nowy sposób identyfikacji łańcuchów receptora limfocytu t delta (lub limfocytu t gamma) lub części tych łańcuchów, które pośredniczą w odpowiedzi przeciwnowotworowej lub przeciwzakaźnej |
| EP3548050A1 (en) | 2016-12-02 | 2019-10-09 | Rubius Therapeutics, Inc. | Compositions and methods related to cell systems for penetrating solid tumors |
| EP3592839B1 (en) * | 2017-03-07 | 2023-07-05 | Universität Basel | Mr1 restricted t cell receptors for cancer immunotherapy |
| CA3063807A1 (en) | 2017-05-18 | 2018-11-22 | Umc Utrecht Holding B.V. | Compositions and methods for cell targeting therapies |
| WO2019219979A1 (en) | 2018-05-18 | 2019-11-21 | Umc Utrecht Holding B.V. | Compositions and methods for cell targeting therapies |
-
2017
- 2017-06-12 PL PL17732050.4T patent/PL3469361T3/pl unknown
- 2017-06-12 CA CA3027124A patent/CA3027124A1/en active Pending
- 2017-06-12 KR KR1020197000215A patent/KR102489954B1/ko active Active
- 2017-06-12 EP EP17733994.2A patent/EP3469362B1/en active Active
- 2017-06-12 WO PCT/EP2017/064323 patent/WO2017212072A1/en not_active Ceased
- 2017-06-12 EP EP22174852.8A patent/EP4099015A1/en active Pending
- 2017-06-12 EP EP24217270.8A patent/EP4527922A3/en not_active Withdrawn
- 2017-06-12 CN CN201780048585.6A patent/CN109997041B/zh active Active
- 2017-06-12 JP JP2018564945A patent/JP2019525898A/ja not_active Ceased
- 2017-06-12 HU HUE17732050A patent/HUE068936T2/hu unknown
- 2017-06-12 CA CA3026180A patent/CA3026180A1/en active Pending
- 2017-06-12 ES ES17732050T patent/ES2987986T3/es active Active
- 2017-06-12 WO PCT/EP2017/064325 patent/WO2017212074A1/en not_active Ceased
- 2017-06-12 EP EP17732050.4A patent/EP3469361B1/en active Active
-
2018
- 2018-12-10 US US16/215,452 patent/US11596654B2/en active Active
- 2018-12-10 US US16/215,456 patent/US11166984B2/en active Active
-
2020
- 2020-12-17 US US17/124,667 patent/US12297274B2/en active Active
-
2023
- 2023-02-17 US US18/170,776 patent/US20230248770A1/en active Pending
-
2024
- 2024-08-19 US US18/808,411 patent/US20250043010A1/en active Pending
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