JP2019525898A5 - - Google Patents
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- Publication number
- JP2019525898A5 JP2019525898A5 JP2018564945A JP2018564945A JP2019525898A5 JP 2019525898 A5 JP2019525898 A5 JP 2019525898A5 JP 2018564945 A JP2018564945 A JP 2018564945A JP 2018564945 A JP2018564945 A JP 2018564945A JP 2019525898 A5 JP2019525898 A5 JP 2019525898A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- polypeptide
- hla
- composition
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16173986.7 | 2016-06-10 | ||
| EP16173970 | 2016-06-10 | ||
| EP16173986 | 2016-06-10 | ||
| EP16173970.1 | 2016-06-10 | ||
| PCT/EP2017/064323 WO2017212072A1 (en) | 2016-06-10 | 2017-06-12 | Human leukocyte antigen restricted gamma delta t cell receptors and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019525898A JP2019525898A (ja) | 2019-09-12 |
| JP2019525898A5 true JP2019525898A5 (enExample) | 2020-07-27 |
Family
ID=59101448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018564945A Ceased JP2019525898A (ja) | 2016-06-10 | 2017-06-12 | ヒト白血球抗原拘束ガンマデルタt細胞受容体及びその使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US11596654B2 (enExample) |
| EP (4) | EP4099015A1 (enExample) |
| JP (1) | JP2019525898A (enExample) |
| KR (1) | KR102489954B1 (enExample) |
| CN (1) | CN109997041B (enExample) |
| CA (2) | CA3027124A1 (enExample) |
| ES (1) | ES2987986T3 (enExample) |
| HU (1) | HUE068936T2 (enExample) |
| PL (1) | PL3469361T3 (enExample) |
| WO (2) | WO2017212074A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2831109T3 (en) | 2012-03-28 | 2018-02-12 | Gadeta B V | COMBINATORY GAMMA-9-DELTA-2-T-CELL RECEPTOR CHAIN EXCHANGE |
| ES2987986T3 (es) | 2016-06-10 | 2024-11-18 | Gadeta B V | Nuevo método para identificar cadenas de receptores de células T delta (o células T gamma) o partes de estas que intervienen en una respuesta antitumoral o antiinfecciosa |
| AU2018268087B2 (en) | 2017-05-18 | 2022-03-17 | Umc Utrecht Holding B.V. | Compositions and methods for cell targeting therapies |
| WO2019156566A1 (en) * | 2018-02-12 | 2019-08-15 | Umc Utrecht Holding B.V. | Bispecific molecules comprising gamma-delta tcr and t-cell or nk cell binding domain |
| US11770910B2 (en) * | 2018-04-23 | 2023-09-26 | Commscope Technologies Llc | Telecommunications enclosure with modular locking system |
| WO2019219979A1 (en) | 2018-05-18 | 2019-11-21 | Umc Utrecht Holding B.V. | Compositions and methods for cell targeting therapies |
| UY38427A (es) | 2018-10-26 | 2020-05-29 | Novartis Ag | Métodos y composiciones para terapia con células oculares |
| US20230348852A1 (en) | 2020-04-27 | 2023-11-02 | Novartis Ag | Methods and compositions for ocular cell therapy |
| WO2021236963A1 (en) * | 2020-05-20 | 2021-11-25 | Chan Zuckerberg Biohub, Inc. | Total rna profiling of biological samples and single cells |
| EP4267604A1 (en) | 2020-12-23 | 2023-11-01 | Gadeta B.V. | Chimeric, transmembrane proteins with bidirectional signalling activity |
| CN113046320B (zh) * | 2021-02-19 | 2023-04-14 | 中国医学科学院基础医学研究所 | 胞外段为Vδ1(GTM)Vγ4的CAR分子及表达该分子的CAR-T细胞及其用途 |
| EP4059955A1 (en) | 2021-03-19 | 2022-09-21 | Medizinische Hochschule Hannover | Hla-dr-specific gamma delta tcr constructs and use thereof |
| WO2022214707A1 (en) | 2021-04-09 | 2022-10-13 | Gadeta B.V. | Cellular reporter and methods of using the same |
| WO2022258606A1 (en) | 2021-06-07 | 2022-12-15 | Gadeta B.V. | Delta T-cell or Gamma T-cell receptor chains or parts thereof that mediate an anti-tumour or anti-infective response |
| EP4370541A1 (en) | 2021-07-14 | 2024-05-22 | 2seventy bio, Inc. | Engineered t cell receptors fused to binding domains from antibodies |
| AU2023248532A1 (en) | 2022-04-08 | 2024-11-21 | Regeneron Pharmaceuticals, Inc. | Multipartite receptor and signaling complexes |
| WO2023227594A1 (en) | 2022-05-24 | 2023-11-30 | Gadeta Bv | Novel deltat-cell receptor chains, gammat-cell receptor chains, or parts thereof |
| WO2023237541A1 (en) | 2022-06-07 | 2023-12-14 | Gadeta B.V. | Delta t-cell or gamma t-cell receptor chains or parts thereof that mediate an anti-tumour or anti-infective response |
| US20260014199A1 (en) | 2022-06-17 | 2026-01-15 | Gadeta B.V. | Modified immune cells |
| US20240075068A1 (en) * | 2022-07-15 | 2024-03-07 | Gadeta B.V. | Novel soluble gamma T-cell (or soluble delta T-cell) receptor chains (or soluble gammadelta T-cell receptors) or fragments thereof that mediate an anti-tumour or an anti-infective response |
| US20240043496A1 (en) * | 2022-07-26 | 2024-02-08 | Gadeta B.V. | Delta t-cell or gamma receptor chains or parts thereof for treating ovarian cancer |
| WO2025231488A1 (en) * | 2024-05-03 | 2025-11-06 | Northwestern University | Gamma-delta t cell receptors for cancer therapy |
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| CA2018248A1 (en) | 1989-06-07 | 1990-12-07 | Clyde W. Shearman | Monoclonal antibodies against the human alpha/beta t-cell receptor, their production and use |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
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| FR2698880B1 (fr) | 1992-11-25 | 1995-02-24 | Inst Nat Sante Rech Med | Procédé de production de récepteurs T solubles, produits ainsi obtenus et leur utilisation dans des compositions diagnostiques ou thérapeutiques. |
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| JP2001332430A (ja) | 2000-05-22 | 2001-11-30 | Murata Mfg Co Ltd | トランス |
| AU2001292842A1 (en) | 2000-09-19 | 2002-04-02 | Diadexus, Inc. | Compositions and methods relating to prostate specific genes and proteins |
| CN1280307C (zh) * | 2001-04-03 | 2006-10-18 | 宝生物工程株式会社 | 细胞毒性t淋巴细胞 |
| US6905827B2 (en) * | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
| US7745140B2 (en) | 2002-01-03 | 2010-06-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool |
| AU2003235593A1 (en) | 2002-01-10 | 2003-07-30 | National Jewish Medical And Research Center | USE OF SOLUBLE GammaDelta T CELL RECEPTORS FOR REGULATING T CELL FUNCTION |
| KR20050048615A (ko) | 2002-08-19 | 2005-05-24 | 제넨테크, 인크. | 종양의 진단 및 치료를 위한 조성물 및 방법 |
| US7749695B2 (en) * | 2003-03-03 | 2010-07-06 | Alexander Abbas | PRO polypeptides for diagnosis of systemic lupus erythematosis |
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| US20050255105A1 (en) | 2004-03-22 | 2005-11-17 | The Board Of Trustees Of The Leland Stanford Junior University | Severe myelin deficits induced by self-reactive gamma delta T cells |
| AU2005250408B2 (en) | 2004-05-27 | 2010-09-23 | The Trustees Of The University Of Pennsylvania | Novel artificial antigen presenting cells and uses therefor |
| WO2006026051A2 (en) * | 2004-08-03 | 2006-03-09 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Selections of genes and methods of using the same for diagnosis, prognosis and for targeting the therapy of neuroblastoma |
| GB0425732D0 (en) | 2004-11-23 | 2004-12-22 | Avidex Ltd | Gamma-delta t cell receptors |
| GB0506760D0 (en) * | 2005-04-01 | 2005-05-11 | Avidex Ltd | High affinity HIV TCRS |
| CA2618580A1 (en) | 2005-08-08 | 2007-02-15 | Fondazione Centro San Raffaele Del Monte Tabor | Use of common .gamma. chain cytokines for the visualization, isolation and genetic modification of memory t lymphocytes |
| DE602005020046D1 (de) * | 2005-09-05 | 2010-04-29 | Immatics Biotechnologies Gmbh | Tumor-assoziierte Peptide, welche an unterschiedliche menschliche Leukozytenantigene der Klasse II binden |
| US9078843B2 (en) * | 2005-09-22 | 2015-07-14 | Irun R. Cohen | Immunogenic fragments of T-cell receptor constant domains and peptides derived therefrom |
| US20080131415A1 (en) | 2006-11-30 | 2008-06-05 | Riddell Stanley R | Adoptive transfer of cd8 + t cell clones derived from central memory cells |
| EP2288700B1 (en) | 2008-05-09 | 2017-02-08 | Agency for Science, Technology And Research | Hbv epitope reactive exogenous t cell receptor (tcr) and uses thereof |
| CN102272153B (zh) | 2008-11-24 | 2015-04-15 | 德国慕尼黑亥姆霍兹研究中心健康和环境有限公司 | 高亲和力t细胞受体及其应用 |
| WO2010087335A1 (ja) | 2009-01-27 | 2010-08-05 | 学校法人産業医科大学 | T細胞抗原受容体遺伝子、受容体α鎖及びβ鎖発現用ベクター並びに細胞障害性T細胞 |
| DK3246042T3 (da) | 2009-11-02 | 2019-10-14 | Univ Emory | Lægemiddelresistent immunterapi til behandling af cancer |
| CN102453701B (zh) | 2010-10-26 | 2014-08-13 | 中国医学科学院基础医学研究所 | 基因修饰CDR3δ移植型γδT淋巴细胞及其抑癌用途 |
| US20150353643A1 (en) | 2013-09-24 | 2015-12-10 | Universite De La Mediterranee - Aix-Marseille Ii | Anti-cd277 antibodies and uses thereof |
| ES2588730T3 (es) | 2011-03-17 | 2016-11-04 | Miltenyi Biotec Gmbh | Preparados celulares agotados en lo que respecta a TCRalfa/beta |
| CN102532269B (zh) * | 2011-05-16 | 2014-07-09 | 中国医学科学院基础医学研究所 | γδT淋巴细胞中δ1链互补决定域3的优势序列及其TCR受体转染细胞与应用 |
| EP2710123B1 (en) | 2011-05-19 | 2017-07-12 | Instituto de Medicina Molecular | Cell line of lymphocytes comprising gamma-delta t cells, composition and production method thereof |
| MX2014001222A (es) | 2011-07-29 | 2014-09-15 | Univ Pennsylvania | Receptores coestimuladores de cambio. |
| DK2831109T3 (en) | 2012-03-28 | 2018-02-12 | Gadeta B V | COMBINATORY GAMMA-9-DELTA-2-T-CELL RECEPTOR CHAIN EXCHANGE |
| WO2014059173A2 (en) | 2012-10-10 | 2014-04-17 | Sangamo Biosciences, Inc. | T cell modifying compounds and uses thereof |
| WO2014179202A1 (en) * | 2013-05-02 | 2014-11-06 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for diagnosis of celiac disease |
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| EP3572510B1 (en) * | 2013-11-21 | 2022-09-21 | Repertoire Genesis Incorporation | T cell receptor and b cell receptor repertoire analysis system, and use of same in treatment and diagnosis |
| KR20240164967A (ko) | 2014-02-04 | 2024-11-21 | 카이트 파마 인코포레이티드 | B 세포 악성종양 및 다른 암을 치료하는데 유용한 자가 t 세포 및 그의 조성물의 생산 방법 |
| KR20170017916A (ko) * | 2014-05-13 | 2017-02-15 | 추가이 세이야쿠 가부시키가이샤 | 면역 억제 기능을 갖는 세포에 대한 t 세포 리다이렉트 항원 결합 분자 |
| JPWO2016195086A1 (ja) | 2015-06-05 | 2018-03-29 | 株式会社メディネット | アレルギー性疾患の治療薬 |
| PT3328894T (pt) | 2015-08-06 | 2019-02-13 | Agency Science Tech & Res | Anticorpos de cadeia comum gama/il2rbeta |
| MA44907A (fr) | 2015-09-11 | 2018-07-18 | Agenus Inc | Cellules hôtes génétiquement modifiées et leurs procédés d'utilisation |
| CN105296431B (zh) * | 2015-11-26 | 2018-10-09 | 北京佳德和细胞治疗技术有限公司 | 肿瘤结合特异性γδTCR基因修饰的αβT细胞及其抑癌用途 |
| US12297427B2 (en) | 2015-12-04 | 2025-05-13 | St. Jude Children's Research Hospital, Inc. | Cloning and expression system for T-cell receptors |
| CN118421557A (zh) | 2016-05-12 | 2024-08-02 | 阿迪塞特治疗公司 | 选择性扩增γδT细胞群的方法及其组合物 |
| US10222369B2 (en) | 2016-05-17 | 2019-03-05 | Chimera Bioengineering, Inc. | Methods for making novel antigen binding domains |
| ES2987986T3 (es) | 2016-06-10 | 2024-11-18 | Gadeta B V | Nuevo método para identificar cadenas de receptores de células T delta (o células T gamma) o partes de estas que intervienen en una respuesta antitumoral o antiinfecciosa |
| BR112019011138A2 (pt) | 2016-12-02 | 2019-10-01 | Rubius Therapeutics, Inc. | composições e métodos relacionados com sistemas celulares para penetração em tumores sólidos |
| AU2018231405B2 (en) * | 2017-03-07 | 2024-02-08 | Universität Basel | MR1 restricted T cell receptors for cancer immunotherapy |
| AU2018268087B2 (en) | 2017-05-18 | 2022-03-17 | Umc Utrecht Holding B.V. | Compositions and methods for cell targeting therapies |
| WO2019219979A1 (en) | 2018-05-18 | 2019-11-21 | Umc Utrecht Holding B.V. | Compositions and methods for cell targeting therapies |
-
2017
- 2017-06-12 ES ES17732050T patent/ES2987986T3/es active Active
- 2017-06-12 CA CA3027124A patent/CA3027124A1/en active Pending
- 2017-06-12 JP JP2018564945A patent/JP2019525898A/ja not_active Ceased
- 2017-06-12 EP EP22174852.8A patent/EP4099015A1/en active Pending
- 2017-06-12 CN CN201780048585.6A patent/CN109997041B/zh not_active Expired - Fee Related
- 2017-06-12 WO PCT/EP2017/064325 patent/WO2017212074A1/en not_active Ceased
- 2017-06-12 EP EP24217270.8A patent/EP4527922A3/en not_active Withdrawn
- 2017-06-12 CA CA3026180A patent/CA3026180A1/en active Pending
- 2017-06-12 HU HUE17732050A patent/HUE068936T2/hu unknown
- 2017-06-12 KR KR1020197000215A patent/KR102489954B1/ko active Active
- 2017-06-12 EP EP17732050.4A patent/EP3469361B1/en active Active
- 2017-06-12 EP EP17733994.2A patent/EP3469362B1/en active Active
- 2017-06-12 PL PL17732050.4T patent/PL3469361T3/pl unknown
- 2017-06-12 WO PCT/EP2017/064323 patent/WO2017212072A1/en not_active Ceased
-
2018
- 2018-12-10 US US16/215,452 patent/US11596654B2/en active Active
- 2018-12-10 US US16/215,456 patent/US11166984B2/en active Active
-
2020
- 2020-12-17 US US17/124,667 patent/US12297274B2/en active Active
-
2023
- 2023-02-17 US US18/170,776 patent/US20230248770A1/en not_active Abandoned
-
2024
- 2024-08-19 US US18/808,411 patent/US20250043010A1/en active Pending
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