JP2016513640A5 - - Google Patents
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- JP2016513640A5 JP2016513640A5 JP2016500441A JP2016500441A JP2016513640A5 JP 2016513640 A5 JP2016513640 A5 JP 2016513640A5 JP 2016500441 A JP2016500441 A JP 2016500441A JP 2016500441 A JP2016500441 A JP 2016500441A JP 2016513640 A5 JP2016513640 A5 JP 2016513640A5
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- Prior art keywords
- pharmaceutical composition
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361800102P | 2013-03-15 | 2013-03-15 | |
| US61/800,102 | 2013-03-15 | ||
| PCT/US2014/018743 WO2014149477A1 (en) | 2013-03-15 | 2014-02-26 | Methods for achieving therapeutically effective doses of anti-cd47 agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018201216A Division JP6704974B2 (ja) | 2013-03-15 | 2018-10-25 | 抗ｃｄ４７薬の処理上有効量を達成するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016513640A JP2016513640A (ja) | 2016-05-16 |
| JP2016513640A5 true JP2016513640A5 (enExample) | 2017-03-30 |
| JP6426693B2 JP6426693B2 (ja) | 2018-11-21 |
Family
ID=51580621
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016500441A Active JP6426693B2 (ja) | 2013-03-15 | 2014-02-26 | 抗ｃｄ４７薬の処理上有効量を達成するための方法 |
| JP2018201216A Active JP6704974B2 (ja) | 2013-03-15 | 2018-10-25 | 抗ｃｄ４７薬の処理上有効量を達成するための方法 |
| JP2020084674A Active JP7007422B2 (ja) | 2013-03-15 | 2020-05-13 | 抗ｃｄ４７薬の処理上有効量を達成するための方法 |
| JP2022001223A Active JP7246528B2 (ja) | 2013-03-15 | 2022-01-06 | 抗ｃｄ４７薬の処理上有効量を達成するための方法 |
| JP2023039709A Active JP7562736B2 (ja) | 2013-03-15 | 2023-03-14 | 抗ｃｄ４７薬の処理上有効量を達成するための方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018201216A Active JP6704974B2 (ja) | 2013-03-15 | 2018-10-25 | 抗ｃｄ４７薬の処理上有効量を達成するための方法 |
| JP2020084674A Active JP7007422B2 (ja) | 2013-03-15 | 2020-05-13 | 抗ｃｄ４７薬の処理上有効量を達成するための方法 |
| JP2022001223A Active JP7246528B2 (ja) | 2013-03-15 | 2022-01-06 | 抗ｃｄ４７薬の処理上有効量を達成するための方法 |
| JP2023039709A Active JP7562736B2 (ja) | 2013-03-15 | 2023-03-14 | 抗ｃｄ４７薬の処理上有効量を達成するための方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (8) | US9623079B2 (enExample) |
| EP (3) | EP2970493B1 (enExample) |
| JP (5) | JP6426693B2 (enExample) |
| CN (3) | CN114917336A (enExample) |
| AU (4) | AU2014238105B2 (enExample) |
| CA (1) | CA2903773A1 (enExample) |
| DK (1) | DK2970493T3 (enExample) |
| ES (1) | ES2728066T3 (enExample) |
| IL (1) | IL241347B (enExample) |
| PT (1) | PT2970493T (enExample) |
| WO (1) | WO2014149477A1 (enExample) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI3056514T4 (fi) | 2008-01-15 | 2025-10-06 | Univ Leland Stanford Junior | Menetelmät cd47:n välittämän fagosytoosin manipuloimiseksi |
| US11072655B2 (en) * | 2008-01-15 | 2021-07-27 | The Board Of Trustees Of The Leland Stanford Junior University | Markers of acute myeloid leukemia stem cells |
| PL4160212T3 (pl) | 2008-01-15 | 2024-08-12 | The Board Of Trustees Of The Leland Stanford Junior University | Markery komórek macierzystych ostrej białaczki szpikowej |
| US9221908B2 (en) | 2012-12-12 | 2015-12-29 | Vasculox, Inc. | Therapeutic CD47 antibodies |
| HK1216647A1 (zh) | 2012-12-12 | 2016-11-25 | Vasculox Inc. | 治疗性cd47抗体 |
| JP6426693B2 (ja) | 2013-03-15 | 2018-11-21 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 抗ｃｄ４７薬の処理上有効量を達成するための方法 |
| US10329354B2 (en) | 2013-09-18 | 2019-06-25 | The Board Of Trustees Of The Leland Stanford Junior University | Modulation of efferocytosis pathways for treatment of atherosclerotic disease |
| WO2016065245A1 (en) * | 2014-10-24 | 2016-04-28 | Incept, Llc | Extra luminal scaffold |
| RU2576614C1 (ru) * | 2015-01-19 | 2016-03-10 | ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ УЧРЕЖДЕНИЕ "33 ЦЕНТРАЛЬНЫЙ НАУЧНО-ИССЛЕДОВАТЕЛЬСКИЙ ИСПЫТАТЕЛЬНЫЙ ИНСТИТУТ" Минобороны России | Способ поиска точки с дробным эффектом при определении эффективных доз веществ методом "одной точки" |
| JP6959865B2 (ja) * | 2015-01-21 | 2021-11-05 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | ガイドとして自身のカルレティキュリンを使用して癌細胞を食べるマクロファージ |
| WO2016138306A1 (en) | 2015-02-27 | 2016-09-01 | The Board Of Trustees Of The Leland Stanford Junior University | Combination therapy for treatment of coronary artery disease |
| CN117964732A (zh) | 2015-08-07 | 2024-05-03 | Alx肿瘤生物技术公司 | 具有SIRP-α结构域或其变体的构建体 |
| KR20250007054A (ko) | 2015-09-04 | 2025-01-13 | 프리마토프 테라퓨틱스 인크. | 인간화 항-cd40 항체 및 그의 용도 |
| EP3349787A4 (en) | 2015-09-18 | 2019-03-27 | Arch Oncology, Inc. | THERAPEUTIC CD47 ANTIBODIES |
| AU2016326423A1 (en) | 2015-09-21 | 2018-04-26 | Erasmus University Medical Center | Anti-CD47 antibodies and methods of use |
| WO2017100462A2 (en) * | 2015-12-11 | 2017-06-15 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of cancer with dual targeting of cd47 and egfr |
| EP3405499A4 (en) * | 2016-01-21 | 2020-03-18 | The Board of Trustees of the Leland Stanford Junior University | TREATMENT OF CANCER WITH COMBINATIONS OF IMMUNOREGULATORS |
| KR20230035435A (ko) | 2016-04-15 | 2023-03-13 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 암의 치료에서 항-cd47 제제의 치료적으로 효과적인 용량을 결정하고 달성하는 방법 |
| US9957576B2 (en) | 2016-04-21 | 2018-05-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for determining responsiveness to an anti-CD47 agent |
| EP3448421B1 (en) | 2016-04-29 | 2021-11-03 | The Board of Trustees of the Leland Stanford Junior University | Methods and compositions for the prevention and treatment of surgical adhesions |
| JP7241677B2 (ja) | 2016-07-19 | 2023-03-17 | テバ・ファーマシューティカルズ・オーストラリア・ピーティワイ・リミテッド | 抗ｃｄ４７併用療法 |
| JOP20190009A1 (ar) | 2016-09-21 | 2019-01-27 | Alx Oncology Inc | أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها |
| WO2018075960A1 (en) | 2016-10-21 | 2018-04-26 | Tioma Therapeutics, Inc. | Therapeutic cd47 antibodies |
| EP3532497B1 (en) | 2016-10-26 | 2024-07-24 | The Board of Trustees of the Leland Stanford Junior University | Modified immunoglobulin hinge regions to reduce hemagglutination |
| CA3042583A1 (en) | 2016-11-03 | 2018-05-11 | Trillium Therapeutics Inc. | Improvements in cd47 blockade therapy by hdac inhibitors |
| US11286301B2 (en) | 2017-02-28 | 2022-03-29 | The Board Of Trustees Of The Leland Stanford Junior University | Antifibrotic activity of CD47 blockade |
| US11078272B2 (en) | 2017-03-09 | 2021-08-03 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of pediatric brain tumors with targeting of CD47 pathway |
| EP4368206A3 (en) * | 2017-06-21 | 2024-08-14 | The Board of Trustees of the Leland Stanford Junior University | Dosing parameters for cd47 targeting therapies to hematologic malignancies |
| JP7262440B2 (ja) | 2017-08-02 | 2023-04-21 | フェインズ セラピューティクス，インコーポレーテッド | 抗ｃｄ４７抗体及びその使用 |
| US11802153B2 (en) | 2017-10-18 | 2023-10-31 | Forty Seven, Inc. | Anti-CD47 agent-based ovarian cancer therapy |
| ES2938652T3 (es) | 2017-10-18 | 2023-04-13 | Forty Seven Inc | Tratamiento del cáncer de ovario con anti-CD47 y anti-PD-L1 |
| KR20200091901A (ko) | 2017-12-01 | 2020-07-31 | 시애틀 지네틱스, 인크. | 암을 치료하기 위한 cd47 항체 및 이의 용도 |
| SI3752190T1 (sl) * | 2018-02-12 | 2022-11-30 | Forty Seven, Inc. | Shema zdravljenja proti raku z uporabo protiteles proti CD47 in proti CD20 |
| US11292850B2 (en) | 2018-03-21 | 2022-04-05 | ALX Oncology Inc. | Antibodies against signal-regulatory protein α and methods of use |
| US11591390B2 (en) | 2018-09-27 | 2023-02-28 | Celgene Corporation | SIRP-α binding proteins and methods of use thereof |
| PE20211491A1 (es) | 2018-09-27 | 2021-08-11 | Celgene Corp | PROTEINAS DE FIJACION A SIRPa Y METODOS DE USO DE ESTAS |
| US20220119523A1 (en) * | 2019-02-08 | 2022-04-21 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of cutaneous t cell lymphoma with targeting of cd47 pathway |
| AU2020283811A1 (en) * | 2019-05-24 | 2021-12-16 | Forty Seven, Inc. | Regimes for co-administration of immunotherapeutic agents against c-kit and CD47 |
| AU2020282791A1 (en) | 2019-05-31 | 2021-12-09 | ALX Oncology Inc. | Methods of treating cancer with SIRP alpha Fc fusion in combination with an immune checkpoint inhibitor |
| MA56119A (fr) * | 2019-06-07 | 2022-04-13 | Alx Oncology Inc | Procédés et réactifs pour réduire les interférences de médicaments se liant au cd47 dans des dosages sérologiques |
| MX2022004370A (es) | 2019-10-18 | 2022-05-06 | Forty Seven Inc | Terapias de combinacion para tratar sindromes mielodisplasicos y leucemia mieloide aguda. |
| BR112022008817A2 (pt) | 2019-11-27 | 2022-07-26 | Alx Oncology Inc | Terapias combinadas para tratamento de câncer |
| JP7369297B2 (ja) | 2019-12-17 | 2023-10-25 | ファイザー・インク | Ｃｄ４７、ｐｄ－ｌ１に特異的な抗体、およびその使用 |
| CA3194577A1 (en) * | 2020-10-09 | 2022-04-14 | Sonja SCHREPFER | Methods for triggering safety killing mechanisms using a cd47-sirp.alpha. blockade agent |
| EP4262828A1 (en) | 2020-12-18 | 2023-10-25 | Instil Bio (Uk) Limited | Tumor infiltrating lymphocytes and anti-cd47 therapeutics |
| JP2024520902A (ja) | 2021-05-13 | 2024-05-27 | エーエルエックス オンコロジー インコーポレイテッド | がんを治療するための併用療法 |
| CA3227223A1 (en) * | 2021-07-28 | 2023-02-02 | Actinium Pharmaceuticals, Inc. | Combination radioimmunotherapy and cd47 blockade in the treatment of cancer |
| US12234294B2 (en) | 2021-11-05 | 2025-02-25 | Kiniksa Pharmaceuticals, Gmbh | Pharmaceutical composition of a humanized anti-CD40 antibody |
| EP4670792A2 (en) | 2021-11-19 | 2025-12-31 | KIST (Korea Institute of Science and Technology) | THERAPEUTIC COMPOUNDS FOR RED BLOOD CELL MEDIATED ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL TO A TARGET CELL |
| CA3242941A1 (en) * | 2022-01-10 | 2023-07-13 | Kiniksa Pharmaceuticals, Gmbh | METHODS FOR TREATMENT OR REDUCING THE RISK OF GRAFT REJECTION |
| US20250302953A1 (en) | 2022-02-14 | 2025-10-02 | Sana Biotechnology, Inc. | Methods of treating patients exhibiting a prior failed therapy with hypoimmunogenic cells |
| WO2023183313A1 (en) | 2022-03-22 | 2023-09-28 | Sana Biotechnology, Inc. | Engineering cells with a transgene in b2m or ciita locus and associated compositions and methods |
| CN120202222A (zh) | 2022-11-16 | 2025-06-24 | 勃林格殷格翰国际有限公司 | 抗SIRPa抗体的疗效预测性生物标志物 |
| KR20250116736A (ko) | 2022-12-09 | 2025-08-01 | 화이자 인코포레이티드 | Cd47 차단제 및 항-bcma/항-cd3 이중특이성 항체 병용 요법 |
| EP4630034A2 (en) | 2022-12-09 | 2025-10-15 | Pfizer Inc. | Cd47 blocking agent and anti-cd20 / anti-cd3 bispecific antibody combination therapy |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020052309A1 (en) * | 1996-09-11 | 2002-05-02 | Athanasius A. Anagnostou | Method of treating endothelial injury |
| AU2002315052A1 (en) * | 2001-05-15 | 2002-11-25 | Emory University | Polynucleotides and polypeptides relating to the modulation of sirp alpha-cd47 |
| US20040213792A1 (en) | 2003-04-24 | 2004-10-28 | Clemmons David R. | Method for inhibiting cellular activation by insulin-like growth factor-1 |
| US20070113297A1 (en) * | 2005-09-13 | 2007-05-17 | Yongguang Yang | Methods and compositions for inhibition of immune responses |
| US8377448B2 (en) | 2006-05-15 | 2013-02-19 | The Board Of Trustees Of The Leland Standford Junior University | CD47 related compositions and methods for treating immunological diseases and disorders |
| CA2702217A1 (en) * | 2007-10-11 | 2009-04-16 | Jayne Danska | Modulation of sirp.alpha. - cd47 interaction for increasing human hematopoietic stem cell engraftment and compounds therefor |
| CN101456911A (zh) | 2007-12-12 | 2009-06-17 | 江苏豪森药业股份有限公司 | 促红细胞生成素模拟肽衍生物及其可药用盐和其制备方法与用途 |
| FI3056514T4 (fi) * | 2008-01-15 | 2025-10-06 | Univ Leland Stanford Junior | Menetelmät cd47:n välittämän fagosytoosin manipuloimiseksi |
| PL4160212T3 (pl) | 2008-01-15 | 2024-08-12 | The Board Of Trustees Of The Leland Stanford Junior University | Markery komórek macierzystych ostrej białaczki szpikowej |
| EP2111869A1 (en) | 2008-04-23 | 2009-10-28 | Stichting Sanquin Bloedvoorziening | Compositions and methods to enhance the immune system |
| US8758750B2 (en) * | 2009-09-15 | 2014-06-24 | The Board Of Trustees Of The Leland Stanford Junior University | Synergistic anti-CD47 therapy for hematologic cancers |
| WO2011041453A1 (en) * | 2009-09-29 | 2011-04-07 | The Board Of Trustees Of The Leland Stanford Junior University | Isolation and use of melanoma cancer stem cells |
| WO2011143624A2 (en) | 2010-05-14 | 2011-11-17 | The Board Of Trustees Of The Leland Stanford Junior University | Humanized and chimeric monoclonal antibodies to cd47 |
| EP3766511A1 (en) * | 2012-01-17 | 2021-01-20 | The Board of Trustees of the Leland Stanford Junior University | High affinity sirp-alpha reagents |
| US20140140989A1 (en) * | 2012-02-06 | 2014-05-22 | Inhibrx Llc | Non-Platelet Depleting and Non-Red Blood Cell Depleting CD47 Antibodies and Methods of Use Thereof |
| KR102338833B1 (ko) * | 2012-02-06 | 2021-12-13 | 인히브릭스, 인크. | Cd47 항체 및 그 사용 방법 |
| AU2013285355A1 (en) | 2012-07-06 | 2015-01-29 | Genmab B.V. | Dimeric protein with triple mutations |
| WO2014123580A1 (en) * | 2013-02-06 | 2014-08-14 | Inhibrx Llc | Non-platelet depleting and non-red blood cell depleting cd47 antibodies and methods of use thereof |
| JP6426693B2 (ja) | 2013-03-15 | 2018-11-21 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 抗ｃｄ４７薬の処理上有効量を達成するための方法 |
-
2014
- 2014-02-26 JP JP2016500441A patent/JP6426693B2/ja active Active
- 2014-02-26 EP EP14768797.4A patent/EP2970493B1/en active Active
- 2014-02-26 US US14/769,069 patent/US9623079B2/en active Active
- 2014-02-26 AU AU2014238105A patent/AU2014238105B2/en active Active
- 2014-02-26 DK DK14768797.4T patent/DK2970493T3/da active
- 2014-02-26 PT PT14768797T patent/PT2970493T/pt unknown
- 2014-02-26 EP EP19166334.3A patent/EP3536709A1/en active Pending
- 2014-02-26 CN CN202210327266.1A patent/CN114917336A/zh active Pending
- 2014-02-26 WO PCT/US2014/018743 patent/WO2014149477A1/en not_active Ceased
- 2014-02-26 CA CA2903773A patent/CA2903773A1/en active Pending
- 2014-02-26 ES ES14768797T patent/ES2728066T3/es active Active
- 2014-02-26 CN CN202010960541.4A patent/CN112245586A/zh active Pending
- 2014-02-26 EP EP20201319.9A patent/EP3792285A1/en not_active Ceased
- 2014-02-26 CN CN201480015159.9A patent/CN105189556A/zh active Pending
-
2015
- 2015-09-09 IL IL241347A patent/IL241347B/en active IP Right Grant
-
2017
- 2017-02-02 US US15/423,325 patent/US10301387B2/en active Active
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2018
- 2018-10-25 JP JP2018201216A patent/JP6704974B2/ja active Active
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2019
- 2019-01-17 AU AU2019200294A patent/AU2019200294B2/en active Active
- 2019-04-04 US US16/375,238 patent/US11104731B2/en active Active
-
2020
- 2020-05-13 JP JP2020084674A patent/JP7007422B2/ja active Active
- 2020-11-17 AU AU2020270485A patent/AU2020270485B2/en active Active
- 2020-11-23 US US17/102,183 patent/US11136391B2/en active Active
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2021
- 2021-08-12 US US17/401,046 patent/US12258399B2/en active Active
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2022
- 2022-01-06 JP JP2022001223A patent/JP7246528B2/ja active Active
- 2022-05-02 US US17/734,904 patent/US11603404B2/en active Active
- 2022-05-02 US US17/734,949 patent/US11518806B2/en active Active
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2023
- 2023-02-03 US US18/164,252 patent/US12258403B2/en active Active
- 2023-03-14 JP JP2023039709A patent/JP7562736B2/ja active Active
-
2024
- 2024-08-20 AU AU2024210996A patent/AU2024210996A1/en active Pending
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