JP2015511226A5 - - Google Patents
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- JP2015511226A5 JP2015511226A5 JP2014554975A JP2014554975A JP2015511226A5 JP 2015511226 A5 JP2015511226 A5 JP 2015511226A5 JP 2014554975 A JP2014554975 A JP 2014554975A JP 2014554975 A JP2014554975 A JP 2014554975A JP 2015511226 A5 JP2015511226 A5 JP 2015511226A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- sample
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- patient
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261593249P | 2012-01-31 | 2012-01-31 | |
| US61/593,249 | 2012-01-31 | ||
| PCT/US2013/023921 WO2013116385A1 (en) | 2012-01-31 | 2013-01-30 | Predictive biomarker for hypoxia-activated prodrug therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017214327A Division JP2018052956A (ja) | 2012-01-31 | 2017-11-07 | 低酸素活性化プロドラッグ療法のための予測バイオマーカー |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015511226A JP2015511226A (ja) | 2015-04-16 |
| JP2015511226A5 true JP2015511226A5 (enExample) | 2016-03-17 |
Family
ID=48905801
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014554975A Pending JP2015511226A (ja) | 2012-01-31 | 2013-01-30 | 低酸素活性化プロドラッグ療法のための予測バイオマーカー |
| JP2017214327A Withdrawn JP2018052956A (ja) | 2012-01-31 | 2017-11-07 | 低酸素活性化プロドラッグ療法のための予測バイオマーカー |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017214327A Withdrawn JP2018052956A (ja) | 2012-01-31 | 2017-11-07 | 低酸素活性化プロドラッグ療法のための予測バイオマーカー |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20150005264A1 (enExample) |
| EP (1) | EP2810076A4 (enExample) |
| JP (2) | JP2015511226A (enExample) |
| WO (1) | WO2013116385A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8003625B2 (en) | 2005-06-29 | 2011-08-23 | Threshold Pharmaceuticals, Inc. | Phosphoramidate alkylator prodrugs |
| US9254299B2 (en) | 2011-12-22 | 2016-02-09 | Threshold Pharmaceuticals, Inc. | Administration of hypoxia activated prodrugs in combination with Chk1 inhibitors for treating cancer |
| WO2015025283A2 (en) * | 2013-08-20 | 2015-02-26 | Stichting Maastricht Radiation Oncology "Maastro-Clinic" | Dual action carbonic anhydrase inhibitors |
| US10071109B2 (en) | 2013-11-06 | 2018-09-11 | Molecular Templates, Inc. | Predictive biomarker for hypoxia-activated prodrug therapy |
| WO2016081547A1 (en) * | 2014-11-19 | 2016-05-26 | Merck Patent Gmbh | Predictive biomarker for hypoxia-activated prodrug therapy |
| EP4549467A3 (en) * | 2016-08-01 | 2025-07-23 | ImmunoGenesis, Inc. | Administration of hypoxia activated prodrugs in combination with immune modulatory agents for treating cancer |
| US20240366640A1 (en) | 2021-08-27 | 2024-11-07 | Ascentawits Pharmaceuticals, Ltd. | Lyophilized formulation solution and lyophilized formulation, and method and use thereof |
| JP7762796B2 (ja) | 2021-08-27 | 2025-10-30 | アセンタウィッツ ファーマシューティカルズ リミテッド | Ｐａｒｐ阻害剤に耐性のある患者のｔｈ－３０２による治療 |
| WO2023174319A1 (zh) | 2022-03-15 | 2023-09-21 | 深圳艾欣达伟医药科技有限公司 | 治疗brca突变癌症患者的方法 |
| CN119384281A (zh) | 2022-04-15 | 2025-01-28 | 深圳艾欣达伟医药科技有限公司 | 使用th-302单药或联用parp抑制剂治疗癌症的方法 |
| EP4529926A1 (en) | 2022-05-23 | 2025-04-02 | Ascentawits Pharmaceuticals, Ltd. | Method for treating cancer by combining alkylating agent prodrug and cell cycle inhibitor |
| WO2024061346A1 (zh) | 2022-09-22 | 2024-03-28 | 深圳艾欣达伟医药科技有限公司 | 乏氧激活的化合物在制备治疗癌症患者的药物中的用途 |
| WO2024179467A1 (zh) | 2023-02-27 | 2024-09-06 | 深圳艾欣达伟医药科技有限公司 | 溶液、冻干制剂、冻干制剂单位包装、注射液及注射液配制方法 |
| CN121646480A (zh) | 2023-07-28 | 2026-03-10 | 深圳艾欣达伟医药科技有限公司 | 治疗p53基因突变或缺陷阴性癌症、肿瘤患者 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1487972T3 (en) * | 2002-02-21 | 2015-10-19 | Inst Virology | MN / CA IX-specific monoclonal antibodies generated from MN / CA IX-poor mice, as well as methods of use. |
| AU2005241093B2 (en) * | 2004-05-04 | 2008-06-05 | Institute Of Virology Of Slovak Academy Of Sciences | MN/CA IX/ CA9 and renal cancer prognosis |
| US20140010805A1 (en) * | 2010-07-12 | 2014-01-09 | Karen Curd | Administration of hypoxia activated prodrugs and antiangiogenic agents for the treatment of cancer |
-
2013
- 2013-01-30 WO PCT/US2013/023921 patent/WO2013116385A1/en not_active Ceased
- 2013-01-30 US US14/375,417 patent/US20150005264A1/en not_active Abandoned
- 2013-01-30 JP JP2014554975A patent/JP2015511226A/ja active Pending
- 2013-01-30 EP EP13744373.5A patent/EP2810076A4/en not_active Withdrawn
-
2017
- 2017-11-07 JP JP2017214327A patent/JP2018052956A/ja not_active Withdrawn
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