KR102489954B1 - 인간 백혈구 항원 제한된 감마 델타 t 세포 수용체 및 이의 사용 방법 - Google Patents

인간 백혈구 항원 제한된 감마 델타 t 세포 수용체 및 이의 사용 방법 Download PDF

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KR102489954B1
KR102489954B1 KR1020197000215A KR20197000215A KR102489954B1 KR 102489954 B1 KR102489954 B1 KR 102489954B1 KR 1020197000215 A KR1020197000215 A KR 1020197000215A KR 20197000215 A KR20197000215 A KR 20197000215A KR 102489954 B1 KR102489954 B1 KR 102489954B1
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KR20190039397A (ko
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위르겐 허버트 에른스트 쿠발
귀도 요리스 잔 키에르켈스
즈솔트 세베슈티옌
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가데타 비.브이.
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KR1020197000215A 2016-06-10 2017-06-12 인간 백혈구 항원 제한된 감마 델타 t 세포 수용체 및 이의 사용 방법 Active KR102489954B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP16173970 2016-06-10
EP16173970.1 2016-06-10
EP16173986 2016-06-10
EP16173986.7 2016-06-10
PCT/EP2017/064323 WO2017212072A1 (en) 2016-06-10 2017-06-12 Human leukocyte antigen restricted gamma delta t cell receptors and methods of use thereof

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KR20190039397A KR20190039397A (ko) 2019-04-11
KR102489954B1 true KR102489954B1 (ko) 2023-01-19

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US (5) US11166984B2 (enExample)
EP (4) EP4099015A1 (enExample)
JP (1) JP2019525898A (enExample)
KR (1) KR102489954B1 (enExample)
CN (1) CN109997041B (enExample)
CA (2) CA3026180A1 (enExample)
ES (1) ES2987986T3 (enExample)
HU (1) HUE068936T2 (enExample)
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WO (2) WO2017212074A1 (enExample)

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WO2019156566A1 (en) * 2018-02-12 2019-08-15 Umc Utrecht Holding B.V. Bispecific molecules comprising gamma-delta tcr and t-cell or nk cell binding domain
BR112020021449A2 (pt) * 2018-04-23 2021-01-19 Commscope Technologies Llc Gabinete de telecomunicações com sistema de bloqueio modular
WO2019219979A1 (en) 2018-05-18 2019-11-21 Umc Utrecht Holding B.V. Compositions and methods for cell targeting therapies
UY38427A (es) 2018-10-26 2020-05-29 Novartis Ag Métodos y composiciones para terapia con células oculares
US20230348852A1 (en) 2020-04-27 2023-11-02 Novartis Ag Methods and compositions for ocular cell therapy
EP4267604A1 (en) 2020-12-23 2023-11-01 Gadeta B.V. Chimeric, transmembrane proteins with bidirectional signalling activity
CN113046320B (zh) * 2021-02-19 2023-04-14 中国医学科学院基础医学研究所 胞外段为Vδ1(GTM)Vγ4的CAR分子及表达该分子的CAR-T细胞及其用途
EP4059955A1 (en) 2021-03-19 2022-09-21 Medizinische Hochschule Hannover Hla-dr-specific gamma delta tcr constructs and use thereof
WO2022214707A1 (en) 2021-04-09 2022-10-13 Gadeta B.V. Cellular reporter and methods of using the same
WO2022258606A1 (en) 2021-06-07 2022-12-15 Gadeta B.V. Delta T-cell or Gamma T-cell receptor chains or parts thereof that mediate an anti-tumour or anti-infective response
EP4370541A1 (en) 2021-07-14 2024-05-22 2seventy bio, Inc. Engineered t cell receptors fused to binding domains from antibodies
CN119546327A (zh) 2022-04-08 2025-02-28 再生元制药公司 多部分受体和信号传导复合物
WO2023227594A1 (en) 2022-05-24 2023-11-30 Gadeta Bv Novel deltat-cell receptor chains, gammat-cell receptor chains, or parts thereof
WO2023237541A1 (en) 2022-06-07 2023-12-14 Gadeta B.V. Delta t-cell or gamma t-cell receptor chains or parts thereof that mediate an anti-tumour or anti-infective response
WO2023242434A1 (en) 2022-06-17 2023-12-21 Gadeta B.V. Modified immune cells
WO2024013401A1 (en) * 2022-07-15 2024-01-18 Gadeta B.V. Novel method for identifying gamma t-cell (or delta t-cell) receptor chains (or gammadelta t-cell receptors) or fragments thereof that mediate an anti-tumour or an anti-infective response
US20240043496A1 (en) * 2022-07-26 2024-02-08 Gadeta B.V. Delta t-cell or gamma receptor chains or parts thereof for treating ovarian cancer
WO2025231488A1 (en) * 2024-05-03 2025-11-06 Northwestern University Gamma-delta t cell receptors for cancer therapy

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