JP2019523295A5 - - Google Patents
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- JP2019523295A5 JP2019523295A5 JP2019517209A JP2019517209A JP2019523295A5 JP 2019523295 A5 JP2019523295 A5 JP 2019523295A5 JP 2019517209 A JP2019517209 A JP 2019517209A JP 2019517209 A JP2019517209 A JP 2019517209A JP 2019523295 A5 JP2019523295 A5 JP 2019523295A5
- Authority
- JP
- Japan
- Prior art keywords
- myostatin
- pharmaceutical composition
- smn
- sma
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662349596P | 2016-06-13 | 2016-06-13 | |
| US62/349,596 | 2016-06-13 | ||
| US201762470157P | 2017-03-10 | 2017-03-10 | |
| US62/470,157 | 2017-03-10 | ||
| US201762486934P | 2017-04-18 | 2017-04-18 | |
| US62/486,934 | 2017-04-18 | ||
| US201762511702P | 2017-05-26 | 2017-05-26 | |
| US62/511,702 | 2017-05-26 | ||
| US201762512254P | 2017-05-30 | 2017-05-30 | |
| US62/512,254 | 2017-05-30 | ||
| PCT/US2017/037332 WO2017218592A1 (en) | 2016-06-13 | 2017-06-13 | Use of myostatin inhibitors and combination therapies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021000367A Division JP7161554B2 (ja) | 2016-06-13 | 2021-01-05 | ミオスタチン阻害剤の使用および併用療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019523295A JP2019523295A (ja) | 2019-08-22 |
| JP2019523295A5 true JP2019523295A5 (https=) | 2020-07-16 |
| JP6823167B2 JP6823167B2 (ja) | 2021-01-27 |
Family
ID=59093642
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019517209A Active JP6823167B2 (ja) | 2016-06-13 | 2017-06-13 | ミオスタチン阻害剤の使用および併用療法 |
| JP2021000367A Active JP7161554B2 (ja) | 2016-06-13 | 2021-01-05 | ミオスタチン阻害剤の使用および併用療法 |
| JP2022064360A Active JP7344337B2 (ja) | 2016-06-13 | 2022-04-08 | ミオスタチン阻害剤の使用および併用療法 |
| JP2023142275A Pending JP2023164920A (ja) | 2016-06-13 | 2023-09-01 | ミオスタチン阻害剤の使用および併用療法 |
| JP2025136177A Pending JP2025183233A (ja) | 2016-06-13 | 2025-08-19 | ミオスタチン阻害剤の使用および併用療法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021000367A Active JP7161554B2 (ja) | 2016-06-13 | 2021-01-05 | ミオスタチン阻害剤の使用および併用療法 |
| JP2022064360A Active JP7344337B2 (ja) | 2016-06-13 | 2022-04-08 | ミオスタチン阻害剤の使用および併用療法 |
| JP2023142275A Pending JP2023164920A (ja) | 2016-06-13 | 2023-09-01 | ミオスタチン阻害剤の使用および併用療法 |
| JP2025136177A Pending JP2025183233A (ja) | 2016-06-13 | 2025-08-19 | ミオスタチン阻害剤の使用および併用療法 |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US10946036B2 (https=) |
| EP (3) | EP3368069B1 (https=) |
| JP (5) | JP6823167B2 (https=) |
| KR (5) | KR20230028813A (https=) |
| AU (4) | AU2017283546C1 (https=) |
| CL (1) | CL2018003588A1 (https=) |
| CY (1) | CY1123678T1 (https=) |
| DK (2) | DK4218804T3 (https=) |
| ES (1) | ES2830440T3 (https=) |
| FI (1) | FI4218804T3 (https=) |
| HR (2) | HRP20260160T1 (https=) |
| HU (1) | HUE051480T2 (https=) |
| IL (3) | IL301468A (https=) |
| LT (2) | LT4218804T (https=) |
| MY (2) | MY185614A (https=) |
| NZ (3) | NZ789269A (https=) |
| PE (1) | PE20190205A1 (https=) |
| PT (1) | PT3368069T (https=) |
| RS (1) | RS61090B1 (https=) |
| SI (2) | SI3368069T1 (https=) |
| SM (1) | SMT202000598T1 (https=) |
| WO (1) | WO2017218592A1 (https=) |
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| CN104761637B (zh) | 2006-03-31 | 2021-10-15 | 中外制药株式会社 | 调控抗体血液动力学的方法 |
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| KR102057826B1 (ko) | 2008-04-11 | 2019-12-20 | 추가이 세이야쿠 가부시키가이샤 | 복수 분자의 항원에 반복 결합하는 항원 결합 분자 |
| EP2647706B1 (en) | 2010-11-30 | 2023-05-17 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
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| CN105246914B (zh) | 2013-04-02 | 2021-08-27 | 中外制药株式会社 | Fc区变体 |
| EP3215175A4 (en) | 2014-11-06 | 2018-06-27 | Scholar Rock, Inc. | Anti-pro/latent-myostatin antibodies and uses thereof |
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| KR102605798B1 (ko) | 2015-02-05 | 2023-11-23 | 추가이 세이야쿠 가부시키가이샤 | 이온 농도 의존적 항원 결합 도메인을 포함하는 항체, Fc 영역 개변체, IL-8에 결합하는 항체, 및 그들의 사용 |
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| EP3494991A4 (en) | 2016-08-05 | 2020-07-29 | Chugai Seiyaku Kabushiki Kaisha | COMPOSITION FOR THE PROPHYLAXIS OR TREATMENT OF IL-8 RELATED DISEASES |
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| EP4218817A3 (en) * | 2017-01-06 | 2023-09-06 | Scholar Rock, Inc. | Methods for treating metabolic diseases by inhibiting myostatin activation |
| WO2018187209A1 (en) * | 2017-04-03 | 2018-10-11 | Acceleron Pharma Inc. | Compositions and methods for treating spinal muscular atrophy |
| WO2019028440A1 (en) | 2017-08-04 | 2019-02-07 | Skyhawk Therapeutics, Inc. | METHODS AND COMPOSITIONS FOR MODULATING SPLICING |
| WO2019170930A1 (es) * | 2018-03-09 | 2019-09-12 | Universitat De Lleida | Tratamiento para la atrofia muscular espinal |
| WO2019204369A1 (en) * | 2018-04-17 | 2019-10-24 | Applied Stemcell, Inc. | Compositions and methods for treating spinal muscular atrophy |
| CN113677711B (zh) | 2019-01-30 | 2025-05-30 | 供石公司 | TGFβ的LTBP复合特异性抑制剂及其用途 |
| WO2020163248A1 (en) | 2019-02-04 | 2020-08-13 | Skyhawk Therapeutics, Inc. | Methods and compositions for modulating splicing |
| EP3920915A4 (en) | 2019-02-05 | 2022-10-05 | Skyhawk Therapeutics, Inc. | METHODS AND COMPOSITIONS FOR MODULATING SPLICE |
| CN114126613A (zh) | 2019-02-05 | 2022-03-01 | 斯基霍克疗法公司 | 用于调节剪接的方法和组合物 |
| WO2020163544A1 (en) | 2019-02-06 | 2020-08-13 | Skyhawk Therapeutics, Inc. | Methods and compositions for modulating splicing |
| CN113661162A (zh) | 2019-02-06 | 2021-11-16 | 斯基霍克疗法公司 | 用于调节剪接的方法和组合物 |
| CN113993452A (zh) * | 2019-06-19 | 2022-01-28 | 豪夫迈·罗氏有限公司 | 数字生物标志物 |
| JP2022537266A (ja) * | 2019-06-19 | 2022-08-25 | エフ．ホフマン－ラ ロシュ アーゲー | デジタルバイオマーカー |
| US11918570B2 (en) | 2020-04-13 | 2024-03-05 | The Research Foundation For The State University Of New York | Method of treatment for prevention of glucocorticoid toxicity and/or enhancement of muscle regeneration via neutrophil elastase inhibition |
| AU2021369471A1 (en) | 2020-10-26 | 2023-06-15 | Scholar Rock, Inc. | Use of anti-pro/latent myostatin antibody for treating spinal muscular atrophy |
| CA3221555A1 (en) | 2021-06-23 | 2022-12-29 | Kimberly LONG | A myostatin pathway inhibitor in combination with a glp-1 pathway activator for use in treating metabolic disorders |
| EP4370148A1 (en) | 2021-07-14 | 2024-05-22 | Scholar Rock, Inc. | Ltbp complex-specific inhibitors of tgf beta1 and uses thereof |
| WO2023057404A1 (en) * | 2021-10-06 | 2023-04-13 | F. Hoffmann-La Roche Ag | Novel combined administration |
| DK4518970T3 (da) * | 2022-05-04 | 2026-04-07 | Scholar Rock Inc | Anvendelse af myostatinhæmmer til behandling af spinal muskelatrofi |
| EP4638496A1 (en) | 2022-12-22 | 2025-10-29 | Scholar Rock, Inc. | Selective and potent inhibitory antibodies of myostatin activation |
| WO2026008041A1 (zh) * | 2024-07-04 | 2026-01-08 | 江苏恒瑞医药股份有限公司 | 特异性结合潜伏肌生长抑制素的抗原结合分子及其医药用途 |
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2017
- 2017-06-13 NZ NZ789269A patent/NZ789269A/en unknown
- 2017-06-13 KR KR1020237005734A patent/KR20230028813A/ko not_active Ceased
- 2017-06-13 NZ NZ789268A patent/NZ789268A/en unknown
- 2017-06-13 SI SI201730485T patent/SI3368069T1/sl unknown
- 2017-06-13 EP EP17732001.7A patent/EP3368069B1/en active Active
- 2017-06-13 MY MYPI2018002494A patent/MY185614A/en unknown
- 2017-06-13 SM SM20200598T patent/SMT202000598T1/it unknown
- 2017-06-13 AU AU2017283546A patent/AU2017283546C1/en active Active
- 2017-06-13 IL IL301468A patent/IL301468A/en unknown
- 2017-06-13 US US16/308,007 patent/US10946036B2/en active Active
- 2017-06-13 MY MYPI2020004682A patent/MY199499A/en unknown
- 2017-06-13 HR HRP20260160TT patent/HRP20260160T1/hr unknown
- 2017-06-13 LT LTEP23157280.1T patent/LT4218804T/lt unknown
- 2017-06-13 KR KR1020217019817A patent/KR20210082548A/ko not_active Ceased
- 2017-06-13 JP JP2019517209A patent/JP6823167B2/ja active Active
- 2017-06-13 SI SI201731653T patent/SI4218804T1/sl unknown
- 2017-06-13 KR KR1020267004587A patent/KR20260028184A/ko active Pending
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