JP2019520034A5 - - Google Patents
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- JP2019520034A5 JP2019520034A5 JP2018550322A JP2018550322A JP2019520034A5 JP 2019520034 A5 JP2019520034 A5 JP 2019520034A5 JP 2018550322 A JP2018550322 A JP 2018550322A JP 2018550322 A JP2018550322 A JP 2018550322A JP 2019520034 A5 JP2019520034 A5 JP 2019520034A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antigen
- antibody
- human
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022112873A JP7549626B2 (ja) | 2016-04-14 | 2022-07-14 | 新規な抗ＳＩＲＰａ抗体およびそれらの治療適用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662322707P | 2016-04-14 | 2016-04-14 | |
| US62/322,707 | 2016-04-14 | ||
| EP17305182.2 | 2017-02-17 | ||
| EP17305182 | 2017-02-17 | ||
| PCT/EP2017/059071 WO2017178653A2 (en) | 2016-04-14 | 2017-04-14 | NEW ANTI-SIRPa ANTIBODIES AND THEIR THERAPEUTIC APPLICATIONS |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022112873A Division JP7549626B2 (ja) | 2016-04-14 | 2022-07-14 | 新規な抗ＳＩＲＰａ抗体およびそれらの治療適用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019520034A JP2019520034A (ja) | 2019-07-18 |
| JP2019520034A5 true JP2019520034A5 (enExample) | 2020-05-21 |
| JP7491666B2 JP7491666B2 (ja) | 2024-05-28 |
Family
ID=65529144
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018550322A Active JP7491666B2 (ja) | 2016-04-14 | 2017-04-14 | 新規な抗ＳＩＲＰａ抗体およびそれらの治療適用 |
| JP2022112873A Active JP7549626B2 (ja) | 2016-04-14 | 2022-07-14 | 新規な抗ＳＩＲＰａ抗体およびそれらの治療適用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022112873A Active JP7549626B2 (ja) | 2016-04-14 | 2022-07-14 | 新規な抗ＳＩＲＰａ抗体およびそれらの治療適用 |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US11279766B2 (enExample) |
| EP (1) | EP4438626A3 (enExample) |
| JP (2) | JP7491666B2 (enExample) |
| KR (1) | KR102355240B1 (enExample) |
| CN (1) | CN115785272A (enExample) |
| CL (1) | CL2018002898A1 (enExample) |
| DK (1) | DK3443010T3 (enExample) |
| ES (1) | ES2990971T3 (enExample) |
| FI (1) | FI3443010T3 (enExample) |
| HR (1) | HRP20241316T1 (enExample) |
| HU (1) | HUE068840T2 (enExample) |
| IL (1) | IL262251B2 (enExample) |
| LT (1) | LT3443010T (enExample) |
| MA (1) | MA44665B1 (enExample) |
| MD (1) | MD3443010T2 (enExample) |
| MX (1) | MX2018012434A (enExample) |
| PH (1) | PH12018550160B1 (enExample) |
| PL (1) | PL3443010T3 (enExample) |
| RS (1) | RS66062B1 (enExample) |
| SA (1) | SA518400237B1 (enExample) |
| SI (1) | SI3443010T1 (enExample) |
| SM (1) | SMT202400438T1 (enExample) |
| UA (1) | UA126658C2 (enExample) |
| ZA (1) | ZA201806293B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SMT202400438T1 (it) * | 2016-04-14 | 2024-11-15 | Ose Immunotherapeutics | Nuovi anticorpi anti-sirpa e loro applicazioni terapeutiche |
| JOP20190009A1 (ar) | 2016-09-21 | 2019-01-27 | Alx Oncology Inc | أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها |
| CN111448210B (zh) * | 2017-07-26 | 2024-05-14 | 四十七公司 | 抗SIRP-α抗体及相关方法 |
| JP7395471B2 (ja) * | 2017-10-13 | 2023-12-11 | オーセ イミュノセラピューティクス | 改変抗ＳＩＲＰａ抗体及びその使用 |
| CN112105646A (zh) | 2018-03-13 | 2020-12-18 | Ose免疫疗法 | 抗人SIRPa v1抗体的用途和生产抗SIRPa v1抗体的方法 |
| US11292850B2 (en) | 2018-03-21 | 2022-04-05 | ALX Oncology Inc. | Antibodies against signal-regulatory protein α and methods of use |
| PE20211491A1 (es) | 2018-09-27 | 2021-08-11 | Celgene Corp | PROTEINAS DE FIJACION A SIRPa Y METODOS DE USO DE ESTAS |
| US11591390B2 (en) | 2018-09-27 | 2023-02-28 | Celgene Corporation | SIRP-α binding proteins and methods of use thereof |
| MX2022004370A (es) | 2019-10-18 | 2022-05-06 | Forty Seven Inc | Terapias de combinacion para tratar sindromes mielodisplasicos y leucemia mieloide aguda. |
| WO2021087064A1 (en) | 2019-10-31 | 2021-05-06 | Forty Seven, Inc. | Anti-cd47 and anti-cd20 based treatment of blood cancer |
| CN112574310B (zh) | 2020-12-11 | 2023-05-05 | 浙江博锐生物制药有限公司 | 抗SIRPα抗体及其用途 |
| KR102896511B1 (ko) * | 2022-09-07 | 2025-12-08 | 주식회사 시프트바이오 | SIRPα 변이체에 특이적으로 결합하는 항체 |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
| AU1701001A (en) | 1999-11-30 | 2001-06-12 | Eberhard-Karls-Universitat Tubingen Universitatsklinikum | Antibodies against signal regulator proteins |
| US20100215640A1 (en) | 2003-04-24 | 2010-08-26 | The University Of North Carolina At Chapel Hill | Method for inhibiting cellular activation by insulin-like growth factor-1 |
| US8613922B2 (en) | 2003-04-24 | 2013-12-24 | The University Of North Carolina At Chapel Hill | Methods for inhibiting diabetic retinopathy with an antibody against integrin associated protein (IAP) |
| JP3936673B2 (ja) | 2003-06-02 | 2007-06-27 | 国立大学法人群馬大学 | Ｃｄ４７部分ペプチドと抗ｓｈｐｓ−１モノクロナール抗体 |
| EA019344B1 (ru) | 2005-07-01 | 2014-03-31 | МЕДАРЕКС, Эл.Эл.Си. | Человеческие моноклональные антитела против лиганда-1 запрограммированной гибели клеток (pd-l1) и их применения |
| EP1930342B1 (en) | 2006-12-04 | 2012-01-25 | Institut Pasteur | OB-fold used as scaffold for engineering new specific binders |
| CA2702217A1 (en) | 2007-10-11 | 2009-04-16 | Jayne Danska | Modulation of sirp.alpha. - cd47 interaction for increasing human hematopoietic stem cell engraftment and compounds therefor |
| EP3424525A1 (en) | 2007-10-12 | 2019-01-09 | Massachusetts Institute Of Technology | Vaccine nanotechnology |
| FI3056514T4 (fi) | 2008-01-15 | 2025-10-06 | Univ Leland Stanford Junior | Menetelmät cd47:n välittämän fagosytoosin manipuloimiseksi |
| EP2111869A1 (en) | 2008-04-23 | 2009-10-28 | Stichting Sanquin Bloedvoorziening | Compositions and methods to enhance the immune system |
| HUE065752T2 (hu) | 2008-12-09 | 2024-06-28 | Hoffmann La Roche | Anti-PD-L1 antitestek és felhasználásuk T-sejt funkció elõsegítésére |
| US10907209B2 (en) | 2009-05-15 | 2021-02-02 | University Health Network | Compositions and methods for treating hematological cancers targeting the SIRPα CD47 interaction |
| GB201015765D0 (en) | 2010-09-21 | 2010-10-27 | Immatics Biotechnologies Gmbh | Use of myeloid cell biomarkers for the diagnosis of cancer |
| US8883497B2 (en) | 2011-04-28 | 2014-11-11 | University Of Southern California | Human myeloid derived suppressor cell cancer markers |
| US20140193408A1 (en) * | 2011-06-16 | 2014-07-10 | Novartis Ag | Soluble proteins for use as therapeutics |
| US20140242095A1 (en) * | 2011-10-19 | 2014-08-28 | University Health Network | Antibodies and antibody fragments targeting sirp-alpha and their use in treating hematologic cancers |
| KR101981873B1 (ko) | 2011-11-28 | 2019-05-23 | 메르크 파텐트 게엠베하 | 항-ｐｄ-ｌ1 항체 및 그의 용도 |
| EP3766511A1 (en) | 2012-01-17 | 2021-01-20 | The Board of Trustees of the Leland Stanford Junior University | High affinity sirp-alpha reagents |
| WO2014123580A1 (en) | 2013-02-06 | 2014-08-14 | Inhibrx Llc | Non-platelet depleting and non-red blood cell depleting cd47 antibodies and methods of use thereof |
| US10570204B2 (en) | 2013-09-26 | 2020-02-25 | The Medical College Of Wisconsin, Inc. | Methods for treating hematologic cancers |
| AU2015229448B2 (en) * | 2014-03-11 | 2020-09-03 | The Board Of Trustees Of The Leland Stanford Junior University | Anti SIRP-alpha antibodies and Bi-specific Macrophage Enhancing antibodies |
| CN105085679B (zh) * | 2014-04-25 | 2019-01-11 | 上海津曼特生物科技有限公司 | 全人源抗rankl抗体 |
| EP3012271A1 (en) | 2014-10-24 | 2016-04-27 | Effimune | Method and compositions for inducing differentiation of myeloid derived suppressor cell to treat cancer and infectious diseases |
| WO2016205042A1 (en) | 2015-06-16 | 2016-12-22 | The Board Of Trustees Of The Leland Stanford Junior University | SIRPα AGONIST ANTIBODY |
| EP4186927B1 (en) | 2015-10-21 | 2025-04-23 | Ose Immunotherapeutics | Methods and compositions for modifying macrophage polarization into pro-inflammatory cells to treat cancer |
| SMT202400438T1 (it) | 2016-04-14 | 2024-11-15 | Ose Immunotherapeutics | Nuovi anticorpi anti-sirpa e loro applicazioni terapeutiche |
| JOP20190009A1 (ar) | 2016-09-21 | 2019-01-27 | Alx Oncology Inc | أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها |
| JP7173971B2 (ja) | 2016-12-09 | 2022-11-16 | アレクトル エルエルシー | 抗ＳＩＲＰ－α抗体及びその使用方法 |
| PT3443010T (pt) | 2017-02-17 | 2024-10-21 | Ose Immunotherapeutics | Novos anticorpos anti-sirpa e suas aplicações terapêuticas |
| MX2019012233A (es) * | 2017-04-13 | 2020-01-14 | Aduro Biotech Holdings Europe Bv | Anticuerpos anti-sirpa. |
| HUE067040T2 (hu) | 2017-05-16 | 2024-09-28 | Byondis Bv | Anti-SIRPalfa antitestek |
| CN111448210B (zh) | 2017-07-26 | 2024-05-14 | 四十七公司 | 抗SIRP-α抗体及相关方法 |
| JP7395471B2 (ja) | 2017-10-13 | 2023-12-11 | オーセ イミュノセラピューティクス | 改変抗ＳＩＲＰａ抗体及びその使用 |
| CN112105646A (zh) | 2018-03-13 | 2020-12-18 | Ose免疫疗法 | 抗人SIRPa v1抗体的用途和生产抗SIRPa v1抗体的方法 |
| US11292850B2 (en) | 2018-03-21 | 2022-04-05 | ALX Oncology Inc. | Antibodies against signal-regulatory protein α and methods of use |
| TW202448946A (zh) | 2018-05-25 | 2024-12-16 | 美商阿列克特有限責任公司 | 抗-sirpa 抗體及其使用方法 |
| AU2019302152B2 (en) | 2018-07-10 | 2025-07-10 | Daiichi Sankyo Company, Limited | Anti-sirpalpha antibody |
| WO2020033646A1 (en) | 2018-08-08 | 2020-02-13 | Orionis Biosciences, Inc. | SIRP1α TARGETED CHIMERIC PROTEINS AND USES THEREOF |
| PE20211491A1 (es) | 2018-09-27 | 2021-08-11 | Celgene Corp | PROTEINAS DE FIJACION A SIRPa Y METODOS DE USO DE ESTAS |
| WO2020102422A1 (en) | 2018-11-14 | 2020-05-22 | Arch Oncology, Inc. | THERAPEUTIC SIRPα ANTIBODIES |
| CA3118966A1 (en) | 2018-11-15 | 2020-05-22 | Byondis B.V. | Humanized anti-sirpa antibodies |
| WO2020180811A1 (en) | 2019-03-04 | 2020-09-10 | Qilu Puget Sound Biotherapeutics Corporation | Anti-sirp-alpha antibodies |
| WO2021032078A1 (en) | 2019-08-20 | 2021-02-25 | Elpiscience (Suzhou) Biopharma, Ltd. | Novel anti-sirpa antibodies |
| CN111635458B (zh) | 2020-03-20 | 2026-02-17 | 健信生物科技(宁波)有限公司 | 靶向Sirpα的抗体或其抗原结合片段及其制备和应用 |
| CN112010979B (zh) | 2020-08-21 | 2022-05-10 | 博奥信生物技术（南京）有限公司 | 一种抗人SIRPα单克隆抗体及其用途 |
| CN111995682B (zh) | 2020-08-21 | 2022-05-10 | 博奥信生物技术（南京）有限公司 | 抗人SIRPα单克隆抗体及其用途 |
| CN112574310B (zh) | 2020-12-11 | 2023-05-05 | 浙江博锐生物制药有限公司 | 抗SIRPα抗体及其用途 |
-
2017
- 2017-04-14 SM SM20240438T patent/SMT202400438T1/it unknown
- 2017-04-14 CN CN202310060526.8A patent/CN115785272A/zh active Pending
- 2017-04-14 KR KR1020187032968A patent/KR102355240B1/ko active Active
- 2017-04-14 LT LTEPPCT/EP2017/059071T patent/LT3443010T/lt unknown
- 2017-04-14 PH PH1/2018/550160A patent/PH12018550160B1/en unknown
- 2017-04-14 DK DK17718881.0T patent/DK3443010T3/da active
- 2017-04-14 MX MX2018012434A patent/MX2018012434A/es unknown
- 2017-04-14 FI FIEP17718881.0T patent/FI3443010T3/fi active
- 2017-04-14 PL PL17718881.0T patent/PL3443010T3/pl unknown
- 2017-04-14 ES ES17718881T patent/ES2990971T3/es active Active
- 2017-04-14 RS RS20241172A patent/RS66062B1/sr unknown
- 2017-04-14 IL IL262251A patent/IL262251B2/en unknown
- 2017-04-14 MA MA44665A patent/MA44665B1/fr unknown
- 2017-04-14 MD MDE20190221T patent/MD3443010T2/ro unknown
- 2017-04-14 UA UAA201809487A patent/UA126658C2/uk unknown
- 2017-04-14 EP EP24190165.1A patent/EP4438626A3/en active Pending
- 2017-04-14 HR HRP20241316TT patent/HRP20241316T1/hr unknown
- 2017-04-14 US US16/093,062 patent/US11279766B2/en active Active
- 2017-04-14 HU HUE17718881A patent/HUE068840T2/hu unknown
- 2017-04-14 SI SI201731557T patent/SI3443010T1/sl unknown
- 2017-04-14 JP JP2018550322A patent/JP7491666B2/ja active Active
-
2018
- 2018-09-19 ZA ZA2018/06293A patent/ZA201806293B/en unknown
- 2018-10-11 CL CL2018002898A patent/CL2018002898A1/es unknown
- 2018-10-14 SA SA518400237A patent/SA518400237B1/ar unknown
-
2022
- 2022-02-25 US US17/681,219 patent/US12252546B2/en active Active
- 2022-07-14 JP JP2022112873A patent/JP7549626B2/ja active Active
-
2025
- 2025-03-11 US US19/076,531 patent/US20250215108A1/en active Pending
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