JP2019519231A5 - - Google Patents
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- Publication number
- JP2019519231A5 JP2019519231A5 JP2018565020A JP2018565020A JP2019519231A5 JP 2019519231 A5 JP2019519231 A5 JP 2019519231A5 JP 2018565020 A JP2018565020 A JP 2018565020A JP 2018565020 A JP2018565020 A JP 2018565020A JP 2019519231 A5 JP2019519231 A5 JP 2019519231A5
- Authority
- JP
- Japan
- Prior art keywords
- temperature
- polymerase
- enzyme
- nicking
- primers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 43
- 102000004190 Enzymes Human genes 0.000 claims 14
- 108090000790 Enzymes Proteins 0.000 claims 14
- 230000003321 amplification Effects 0.000 claims 10
- 238000003199 nucleic acid amplification method Methods 0.000 claims 10
- 238000006243 chemical reaction Methods 0.000 claims 9
- 108020004707 nucleic acids Proteins 0.000 claims 6
- 102000039446 nucleic acids Human genes 0.000 claims 6
- 150000007523 nucleic acids Chemical class 0.000 claims 6
- 108020004414 DNA Proteins 0.000 claims 3
- 102000006943 Uracil-DNA Glycosidase Human genes 0.000 claims 3
- 108010072685 Uracil-DNA Glycosidase Proteins 0.000 claims 3
- 230000000295 complement effect Effects 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- 239000012491 analyte Substances 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 102000053602 DNA Human genes 0.000 claims 1
- 102000004594 DNA Polymerase I Human genes 0.000 claims 1
- 108010017826 DNA Polymerase I Proteins 0.000 claims 1
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 claims 1
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 claims 1
- 102100034343 Integrase Human genes 0.000 claims 1
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 238000003487 electrochemical reaction Methods 0.000 claims 1
- 239000007850 fluorescent dye Substances 0.000 claims 1
- 239000011541 reaction mixture Substances 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 238000010839 reverse transcription Methods 0.000 claims 1
- 239000000523 sample Substances 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021164854A JP2022017268A (ja) | 2016-06-30 | 2021-10-06 | 核酸増幅プロセスの改善または核酸増幅プロセスに関する改善 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1611469.6 | 2016-06-30 | ||
| GBGB1611469.6A GB201611469D0 (en) | 2016-06-30 | 2016-06-30 | Improvements in or relating to nucleic acid amplification processes |
| PCT/GB2017/051927 WO2018002649A1 (en) | 2016-06-30 | 2017-06-30 | Improvements in or relating to nucleic acid amplification processes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021164854A Division JP2022017268A (ja) | 2016-06-30 | 2021-10-06 | 核酸増幅プロセスの改善または核酸増幅プロセスに関する改善 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019519231A JP2019519231A (ja) | 2019-07-11 |
| JP2019519231A5 true JP2019519231A5 (enExample) | 2020-01-16 |
| JP6957527B2 JP6957527B2 (ja) | 2021-11-02 |
Family
ID=56891177
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018565020A Active JP6957527B2 (ja) | 2016-06-30 | 2017-06-30 | 核酸増幅プロセスの改善または核酸増幅プロセスに関する改善 |
| JP2021164854A Pending JP2022017268A (ja) | 2016-06-30 | 2021-10-06 | 核酸増幅プロセスの改善または核酸増幅プロセスに関する改善 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021164854A Pending JP2022017268A (ja) | 2016-06-30 | 2021-10-06 | 核酸増幅プロセスの改善または核酸増幅プロセスに関する改善 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US11591643B2 (enExample) |
| EP (1) | EP3478853B2 (enExample) |
| JP (2) | JP6957527B2 (enExample) |
| KR (1) | KR102392010B1 (enExample) |
| CN (1) | CN109642251B (enExample) |
| AU (1) | AU2017287852B2 (enExample) |
| CA (1) | CA3024295C (enExample) |
| ES (1) | ES2841624T3 (enExample) |
| GB (1) | GB201611469D0 (enExample) |
| IL (1) | IL263870A (enExample) |
| MX (1) | MX2018015421A (enExample) |
| RU (1) | RU2760915C2 (enExample) |
| SG (1) | SG11201809927XA (enExample) |
| WO (1) | WO2018002649A1 (enExample) |
| ZA (1) | ZA201807460B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201611469D0 (en) | 2016-06-30 | 2016-08-17 | Lumiradx Tech Ltd | Improvements in or relating to nucleic acid amplification processes |
| GB2569965A (en) | 2018-01-04 | 2019-07-10 | Lumiradx Uk Ltd | Improvements in or relating to amplification of nucleic acids |
| GB201812149D0 (en) | 2018-07-25 | 2018-09-05 | Sense Biodetection Ltd | Nucleic acid detection method |
| GB201915346D0 (en) | 2019-06-21 | 2019-12-04 | Lumiradx Tech Ltd | Improvements in or relating to nicking enzymes |
| CN115003828A (zh) | 2020-01-25 | 2022-09-02 | 圣斯生物检测有限公司 | 病毒检测 |
| JP2023517157A (ja) * | 2020-03-09 | 2023-04-24 | イルミナ，インコーポレイテッド | ポリヌクレオチドを配列決定するための方法 |
| EP4347868A1 (en) | 2021-05-27 | 2024-04-10 | Lumiradx Uk Ltd | Improvements in or relating to digestion of reaction products |
| WO2023044028A1 (en) * | 2021-09-16 | 2023-03-23 | Circ, LLC | Method of aging regenerated diacid crystals |
| TW202330758A (zh) | 2021-09-16 | 2023-08-01 | 美商賽克股份有限公司 | 從由廢棄材料解聚合所形成再生二酸形成聚酯之方法 |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2017821C1 (ru) * | 1990-10-10 | 1994-08-15 | Анатолий Михайлович Онищенко | Способ амплификации днк и устройство для его осуществления |
| US5432065A (en) | 1993-03-30 | 1995-07-11 | United States Biochemical Corporation | Cycle sequencing with non-thermostable DNA polymerases |
| US20020025555A1 (en) * | 1997-03-06 | 2002-02-28 | Janice Au-Young | GPCR diagnostic for brain cancer |
| CA2319757C (en) | 1998-01-27 | 2008-01-08 | Cytocell Limited | Method for detection of nucleic acid target sequences involving in vitro transcription from an rna promoter |
| EP1088891B1 (en) | 1999-09-28 | 2005-01-12 | Roche Diagnostics GmbH | Thermostable enzyme promoting the fidelity of thermostable DNA polymerases - for improvement of nucleic acid synthesis and amplification in vitro |
| US20010047200A1 (en) | 1999-10-13 | 2001-11-29 | Raymond Sun | Non-foreshortening intraluminal prosthesis |
| NO314091B1 (no) * | 2000-01-12 | 2003-01-27 | Biotec Pharmacon Asa | Varmelabil uracil-DNA-glykosylase, DNA-sekvens som koder for enzymet, mikroorganisme som inneholder DNA-sekvensen, samt anvendelse av enzymet |
| US6191267B1 (en) | 2000-06-02 | 2001-02-20 | New England Biolabs, Inc. | Cloning and producing the N.BstNBI nicking endonuclease |
| ATE312942T1 (de) | 2000-10-25 | 2005-12-15 | Hoffmann La Roche | Amplifizierung unter verwendung von modifizierten primern |
| GB0101397D0 (en) | 2001-01-19 | 2001-03-07 | Amersham Pharm Biotech Uk Ltd | Suppression of non-specific nucleic acid amplication |
| US20030211506A1 (en) | 2001-06-01 | 2003-11-13 | Huimin Kong | N. bstnbi nicking endonuclease and methods for using endonucleases in single-stranded displacement amplification |
| WO2004022701A2 (en) * | 2001-07-15 | 2004-03-18 | Keck Graduate Institute | Exponential amplification of nucleic acids using nicking agents |
| WO2003048393A1 (en) | 2001-12-04 | 2003-06-12 | Bio3 Research Srl | Mixture of two partially denaturating agents for the preparation of pcr buffer solutions |
| US7399590B2 (en) | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| AU2003289651A1 (en) | 2002-12-18 | 2004-07-09 | Dingbang Xu | Pcr method and application by transnormal low thermo-denaturation temperature |
| CA2521127C (en) | 2003-04-01 | 2014-05-27 | Eragen Biosciences, Inc. | Polymerase inhibitor and method of using same |
| JP5026958B2 (ja) | 2004-06-01 | 2012-09-19 | アリーア サン ディエゴ， インコーポレイテッド | リコンビナーゼポリメラーゼ増幅 |
| US7754473B2 (en) * | 2004-06-04 | 2010-07-13 | Abacus Diagnostica Oy | Temperature control of reaction vessel, system with reaction vessel, software product for system and use of system |
| FR2878254B1 (fr) * | 2004-11-22 | 2010-08-20 | Bio Rad Pasteur | Composition pour l'amplification d'acides nucleiques |
| EP1762627A1 (de) * | 2005-09-09 | 2007-03-14 | Qiagen GmbH | Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion |
| US7537917B2 (en) | 2006-03-31 | 2009-05-26 | Collins Michael J | Microwave assisted PCR amplification of DNA |
| US20090092967A1 (en) | 2006-06-26 | 2009-04-09 | Epoch Biosciences, Inc. | Method for generating target nucleic acid sequences |
| WO2008119081A1 (en) | 2007-03-28 | 2008-10-02 | Signal Diagnostics | System and method for high resolution analysis of nucleic acids to detect sequence variations |
| US9689031B2 (en) | 2007-07-14 | 2017-06-27 | Ionian Technologies, Inc. | Nicking and extension amplification reaction for the exponential amplification of nucleic acids |
| WO2009042291A2 (en) * | 2007-08-03 | 2009-04-02 | Igor Kutyavin | Accelerated cascade amplification (aca) of nucleic acids comprising strand and sequence specific dna nicking |
| FI20085450A0 (fi) | 2008-05-14 | 2008-05-14 | Arto Orpana | Menetelmä DNA-juosteen syntetisoimiseksi |
| GB0915664D0 (en) * | 2009-09-08 | 2009-10-07 | Enigma Diagnostics Ltd | Reaction method |
| CN107739750A (zh) | 2009-09-25 | 2018-02-27 | 艾利尔圣迭戈公司 | 粗基质中的核酸的检测 |
| CN102917796B (zh) * | 2010-04-20 | 2015-04-01 | 科贝特研究私人有限公司 | 温度控制方法和设备 |
| JP6126381B2 (ja) | 2010-12-10 | 2017-05-10 | 国立大学法人東京工業大学 | 標的核酸の検出方法及びキット |
| CN110079588B (zh) | 2010-12-17 | 2024-03-15 | 生命技术公司 | 用于核酸扩增的方法、组合物、系统、仪器和试剂盒 |
| CA2856304C (en) | 2011-04-20 | 2017-05-16 | Mesa Tech International, Inc. | Oscillating amplification reaction for nucleic acids |
| US8343752B2 (en) * | 2011-05-03 | 2013-01-01 | Verdezyne, Inc. | Biological methods for preparing adipic acid |
| BR112014025262A8 (pt) * | 2012-04-09 | 2021-06-29 | Envirologix Inc | métodos para quantificar um produto específico em uma reação de amplificação de extensão e corte, para detectar uma pluralidade de produtos de reação distintos produzidos ao longo de uma única reação, para monitorar em tempo real uma reação de amplificação de extensão e corte, para monitorar em tempo real uma molécula-alvo de ácido nucleico em uma reação de amplificação de extensão e corte, para monitorar em tempo real uma molécula-alvo de ácido nucleico em uma amostra de teste, e para amplificar um polinucleotídeo, kit, e, oligonucleotídeo isolado |
| CN114214394A (zh) | 2012-06-08 | 2022-03-22 | 爱奥尼安技术公司 | 核苷酸扩增反应 |
| CA2936157C (en) | 2014-01-15 | 2021-08-24 | Tokyo Institute Of Technology | Covered sequence conversion dna and detection methods |
| EP3207159B1 (en) | 2014-10-14 | 2019-11-20 | Abbott Laboratories | Sequence conversion and signal amplifier dna having poly dna spacer sequences and detection methods using same |
| US10604790B2 (en) | 2014-12-24 | 2020-03-31 | Abbott Laboratories | Sequence conversion and signal amplifier DNA cascade reactions and detection methods using same |
| GB201513128D0 (en) | 2015-07-24 | 2015-09-09 | Sense Biodetection Ltd | Nucleic acid detection method |
| EP3334834B1 (en) | 2015-08-12 | 2020-05-13 | Circulogene Theranostics, LLC | Method of preparing cell free nucleic acid molecules by in situ amplification |
| US10329601B2 (en) | 2015-12-28 | 2019-06-25 | Ionian Technologies, Inc. | Nicking and extension amplification reaction (NEAR) of Streptococcus species |
| GB201611469D0 (en) | 2016-06-30 | 2016-08-17 | Lumiradx Tech Ltd | Improvements in or relating to nucleic acid amplification processes |
| GB201701262D0 (en) | 2017-01-25 | 2017-03-08 | Sense Biodetection Ltd | Nucleic acid detection method |
| RU2020100221A (ru) | 2017-08-31 | 2021-09-30 | Иониан Текнолоджис, Ллс | Реакция амплификации с разрывом и удлинением (near) разновидностей респираторно-синцитиального вируса |
| GB2569965A (en) | 2018-01-04 | 2019-07-10 | Lumiradx Uk Ltd | Improvements in or relating to amplification of nucleic acids |
| GB201812149D0 (en) | 2018-07-25 | 2018-09-05 | Sense Biodetection Ltd | Nucleic acid detection method |
-
2016
- 2016-06-30 GB GBGB1611469.6A patent/GB201611469D0/en not_active Ceased
-
2017
- 2017-06-30 RU RU2019101504A patent/RU2760915C2/ru active
- 2017-06-30 WO PCT/GB2017/051927 patent/WO2018002649A1/en not_active Ceased
- 2017-06-30 ES ES17736737T patent/ES2841624T3/es active Active
- 2017-06-30 EP EP17736737.2A patent/EP3478853B2/en active Active
- 2017-06-30 US US16/313,750 patent/US11591643B2/en active Active
- 2017-06-30 CN CN201780040770.0A patent/CN109642251B/zh active Active
- 2017-06-30 JP JP2018565020A patent/JP6957527B2/ja active Active
- 2017-06-30 MX MX2018015421A patent/MX2018015421A/es unknown
- 2017-06-30 SG SG11201809927XA patent/SG11201809927XA/en unknown
- 2017-06-30 KR KR1020187035782A patent/KR102392010B1/ko active Active
- 2017-06-30 CA CA3024295A patent/CA3024295C/en active Active
- 2017-06-30 AU AU2017287852A patent/AU2017287852B2/en active Active
-
2018
- 2018-11-07 ZA ZA2018/07460A patent/ZA201807460B/en unknown
- 2018-12-20 IL IL263870A patent/IL263870A/en unknown
-
2021
- 2021-10-06 JP JP2021164854A patent/JP2022017268A/ja active Pending
-
2023
- 2023-01-26 US US18/102,031 patent/US20230340579A1/en active Pending
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