JP2019518739A5 - - Google Patents

Download PDF

Info

Publication number
JP2019518739A5
JP2019518739A5 JP2018559785A JP2018559785A JP2019518739A5 JP 2019518739 A5 JP2019518739 A5 JP 2019518739A5 JP 2018559785 A JP2018559785 A JP 2018559785A JP 2018559785 A JP2018559785 A JP 2018559785A JP 2019518739 A5 JP2019518739 A5 JP 2019518739A5
Authority
JP
Japan
Prior art keywords
liposome
lipid
peg
mol
pegylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018559785A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019518739A (ja
JP7195147B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/032756 external-priority patent/WO2017200957A1/en
Publication of JP2019518739A publication Critical patent/JP2019518739A/ja
Publication of JP2019518739A5 publication Critical patent/JP2019518739A5/ja
Priority to JP2022143788A priority Critical patent/JP2022177112A/ja
Application granted granted Critical
Publication of JP7195147B2 publication Critical patent/JP7195147B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018559785A 2016-05-16 2017-05-15 Ｐｅｇ化リポソームおよび使用方法 Active JP7195147B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022143788A JP2022177112A (ja) 2016-05-16 2022-09-09 Ｐｅｇ化リポソームおよび使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662337328P 2016-05-16 2016-05-16
US62/337,328 2016-05-16
PCT/US2017/032756 WO2017200957A1 (en) 2016-05-16 2017-05-15 Pegylated liposomes and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022143788A Division JP2022177112A (ja) 2016-05-16 2022-09-09 Ｐｅｇ化リポソームおよび使用方法

Publications (3)

Publication Number Publication Date
JP2019518739A JP2019518739A (ja) 2019-07-04
JP2019518739A5 true JP2019518739A5 (https=) 2020-06-25
JP7195147B2 JP7195147B2 (ja) 2022-12-23

Family

ID=58794159

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018559785A Active JP7195147B2 (ja) 2016-05-16 2017-05-15 Ｐｅｇ化リポソームおよび使用方法
JP2022143788A Pending JP2022177112A (ja) 2016-05-16 2022-09-09 Ｐｅｇ化リポソームおよび使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022143788A Pending JP2022177112A (ja) 2016-05-16 2022-09-09 Ｐｅｇ化リポソームおよび使用方法

Country Status (11)

Country Link
US (3) US11266602B2 (https=)
EP (1) EP3458028A1 (https=)
JP (2) JP7195147B2 (https=)
KR (1) KR102483033B1 (https=)
CN (1) CN109562057A (https=)
AU (2) AU2017268175B2 (https=)
BR (1) BR112018073676B1 (https=)
IL (3) IL263030B2 (https=)
MX (1) MX2018013640A (https=)
WO (1) WO2017200957A1 (https=)
ZA (1) ZA201807128B (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017200957A1 (en) * 2016-05-16 2017-11-23 Infectious Disease Research Institute Pegylated liposomes and methods of use
BR112019025104A2 (pt) 2017-05-30 2020-06-23 Glaxosmithkline Biologicals S.A. Método de fabricar um sistema de entrega não viral, sistema de entrega não viral, e, composição
CN107998070A (zh) * 2017-12-12 2018-05-08 南京中医药大学 一种复合磷脂传递体及其在制备经皮给药制剂中的应用
EP3886901A1 (en) 2018-11-29 2021-10-06 GlaxoSmithKline Biologicals S.A. Methods for manufacturing an adjuvant
CN112930184B (zh) * 2018-12-17 2024-07-12 卫材R&D管理有限公司 包含脂质体的配制品
CN110151702A (zh) * 2019-06-24 2019-08-23 昆明医科大学 聚乙二醇修饰流感疫苗脂质体及其制备方法
US11679163B2 (en) 2019-09-20 2023-06-20 Hdt Bio Corp. Compositions and methods for delivery of RNA
KR102328531B1 (ko) * 2020-01-23 2021-11-17 서울대학교산학협력단 체내 면역 세포 표적 황화수소 공여체 담지 리포좀을 포함하는 면역질환 치료 또는 예방용 약학 조성물
KR20220156933A (ko) 2020-03-23 2022-11-28 에이치디티 바이오 코포레이션 Rna의 전달을 위한 조성물 및 방법
CA3186799A1 (en) * 2020-07-22 2022-01-27 Navin VARADARAJAN Treatment and prevention of conditions associated with respiratory diseases
EP4048308A1 (en) 2020-12-23 2022-08-31 Infectious Disease Research Institute Solanesol vaccine adjuvants and methods of preparing same
US20240180834A1 (en) * 2021-02-26 2024-06-06 Univesity Of Virginia Patent Foundation Development of covid-19 vaccine using a dual tlr ligand liposome adjuvant
WO2022192674A1 (en) * 2021-03-11 2022-09-15 The Trustees Of The University Of Pennsylvania Targeted therapeutic lipid nanoparticles and methods of use
CN117510830A (zh) * 2021-04-08 2024-02-06 厦门赛诺邦格生物科技股份有限公司 一种聚乙二醇化脂质及其修饰的脂质体、含该脂质体的药物组合物及其制剂和应用
KR102682082B1 (ko) * 2021-06-01 2024-07-05 서울대학교산학협력단 리포좀 및 이를 포함하는 암 방사선 치료용 약학 조성물
EP4404919A4 (en) 2021-09-22 2025-08-20 Hdt Bio Corp DRIED NANOPARTICLE COMPOSITIONS
JP2024535354A (ja) 2021-09-22 2024-09-30 エイチディーティー バイオ コーポレーション がん治療組成物およびその使用
WO2023048760A1 (en) 2021-09-22 2023-03-30 Hdt Bio Corp. Rna vaccines against infectious diseases
CA3232719A1 (en) 2021-09-22 2023-03-30 Steven Gregory REED Sars-cov-2 rna vaccine compositions and methods of use
WO2024137455A1 (en) * 2022-12-19 2024-06-27 Newimmune Ii, Llc Nanoparticulate formulation
CN115737800B (zh) * 2023-01-09 2023-05-23 江苏瑞科生物技术股份有限公司 一种复合脂质体佐剂及其制备方法
WO2025245466A1 (en) * 2024-05-24 2025-11-27 Curevo, Inc. Immunogenic compositions for the prevention of herpes zoster
CN121533991A (zh) * 2026-01-20 2026-02-17 杭州英妙生物科技有限公司 靶向B细胞或靶向CD11b+细胞的纳米脂质体及其应用

Family Cites Families (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598122A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US4286592A (en) 1980-02-04 1981-09-01 Alza Corporation Therapeutic system for administering drugs to the skin
US4314557A (en) 1980-05-19 1982-02-09 Alza Corporation Dissolution controlled active agent dispenser
US4379454A (en) 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
US4436727A (en) 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
IL73534A (en) 1983-11-18 1990-12-23 Riker Laboratories Inc 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
US4568343A (en) 1984-10-09 1986-02-04 Alza Corporation Skin permeation enhancer compositions
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
FI861417A0 (fi) 1985-04-15 1986-04-01 Endotronics Inc Hepatitis b ytantigen framstaelld med rekombinant-dna-teknik, vaccin, diagnostiskt medel och cellinjer samt foerfaranden foer framstaellning daerav.
US4948587A (en) 1986-07-08 1990-08-14 Massachusetts Institute Of Technology Ultrasound enhancement of transbuccal drug delivery
US4767402A (en) 1986-07-08 1988-08-30 Massachusetts Institute Of Technology Ultrasound enhancement of transdermal drug delivery
US5075109A (en) 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
EP1088830A3 (en) 1987-06-22 2004-04-07 Medeva Holdings B.V. Hepatitis b surface antigen particles
US4780212A (en) 1987-07-31 1988-10-25 Massachusetts Institute Of Technology Ultrasound enchancement of membrane permeability
US4897268A (en) 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
GB2232892B (en) 1988-02-23 1991-07-24 John Mark Tucker Occlusive body for administering a physiologically active substance
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
GB8819209D0 (en) 1988-08-12 1988-09-14 Research Corp Ltd Polypeptide & dna encoding same
US4999403A (en) 1988-10-28 1991-03-12 Exxon Chemical Patents Inc. Graft polymers of functionalized ethylene-alpha-olefin copolymer with polypropylene, methods of preparation, and use in polypropylene compositions
WO1990006951A1 (en) 1988-12-16 1990-06-28 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur Pneumolysin mutants and pneumococcal vaccines made therefrom
EP0414374B1 (en) 1989-07-25 1997-10-08 Smithkline Biologicals S.A. Novel antigens and methods for their preparation
US5256643A (en) 1990-05-29 1993-10-26 The Government Of The United States Human cripto protein
GB9106048D0 (en) 1991-03-21 1991-05-08 Smithkline Beecham Biolog Vaccines
ES2194839T3 (es) 1991-07-19 2003-12-01 Univ Queensland Vacuna de papilomavirus.
US5464387A (en) 1991-07-24 1995-11-07 Alza Corporation Transdermal delivery device
AU2927892A (en) 1991-11-16 1993-06-15 Smithkline Beecham Biologicals (Sa) Hybrid protein between cs from plasmodium and hbsag
EP1835029A1 (en) 1992-06-25 2007-09-19 Georgetown University Papillomavirus vaccines
US5786148A (en) 1996-11-05 1998-07-28 Incyte Pharmaceuticals, Inc. Polynucleotides encoding a novel prostate-specific kallikrein
US5437951A (en) 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
ATE492289T1 (de) 1993-03-09 2011-01-15 Univ Rochester Herstellung von menschlichen papillomavirus hbv- 11 kapsidprotein l1 und virus-ähnliche partikeln
JPH09500128A (ja) 1993-07-15 1997-01-07 ミネソタ マイニング アンド マニュファクチャリング カンパニー イミダゾ〔４，５−ｃ〕ピリジン−４−アミン
DE69418143T2 (de) 1993-11-02 1999-08-26 Matsushita Electric Industrial Co. Verfahren zur Herstellung eines Aggregats von Mikro-Nadeln aus Halbleitermaterial
US5885211A (en) 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
US5458140A (en) 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
US5814599A (en) 1995-08-04 1998-09-29 Massachusetts Insitiute Of Technology Transdermal delivery of encapsulated drugs
US5688506A (en) 1994-01-27 1997-11-18 Aphton Corp. Immunogens against gonadotropin releasing hormone
US5457041A (en) 1994-03-25 1995-10-10 Science Applications International Corporation Needle array and method of introducing biological substances into living cells using the needle array
US5591139A (en) 1994-06-06 1997-01-07 The Regents Of The University Of California IC-processed microneedles
DE122007000092I1 (de) 1994-10-07 2008-03-27 Univ Loyola Chicago Papillomavirusähnliche partikel, fusionsproteine sowie verfahren zu deren herstellung
JP3958360B2 (ja) 1995-02-24 2007-08-15 キャンタブ ファーマシューティカルズ リサーチ リミティド 免疫治療剤として役立つポリペプチド及びポリペプチド調製の方法
US5843464A (en) 1995-06-02 1998-12-01 The Ohio State University Synthetic chimeric fimbrin peptides
US5981215A (en) 1995-06-06 1999-11-09 Human Genome Sciences, Inc. Human criptin growth factor
US5618275A (en) 1995-10-27 1997-04-08 Sonex International Corporation Ultrasonic method and apparatus for cosmetic and dermatological applications
US5656016A (en) 1996-03-18 1997-08-12 Abbott Laboratories Sonophoretic drug delivery system
US5955306A (en) 1996-09-17 1999-09-21 Millenium Pharmaceuticals, Inc. Genes encoding proteins that interact with the tub protein
US7033598B2 (en) 1996-11-19 2006-04-25 Intrabrain International N.V. Methods and apparatus for enhanced and controlled delivery of a biologically active agent into the central nervous system of a mammal
US5840871A (en) 1997-01-29 1998-11-24 Incyte Pharmaceuticals, Inc. Prostate-associated kallikrein
CA2281954A1 (en) 1997-02-25 1998-08-27 Corixa Corporation Compounds for immunodiagnosis of prostate cancer and methods for their use
EP0998557A2 (en) 1997-07-21 2000-05-10 North American Vaccine, Inc. Modified immunogenic pneumolysin, compositions and their use as vaccines
GB9717953D0 (en) 1997-08-22 1997-10-29 Smithkline Beecham Biolog Vaccine
US7459524B1 (en) 1997-10-02 2008-12-02 Emergent Product Development Gaithersburg Inc. Chlamydia protein, sequence and uses thereof
EP2218731A1 (en) 1997-11-28 2010-08-18 Merck Serono Biodevelopment Chlamydia trachomatis genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection
UA67760C2 (uk) 1997-12-11 2004-07-15 Міннесота Майнінг Енд Мануфакчурінг Компані Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки
CZ298364B6 (cs) 1998-02-05 2007-09-05 Smithkline Beecham Biologicals S. A. Deriváty antigenu asociovaných s nádory z MAGE rodiny a sekvence nukleových kyselin kodující tyto deriváty, jejich použití pro prípravu fúzních proteinu a prostredku pro vakcinaci
PL202844B1 (pl) 1998-04-07 2009-07-31 Corixa Corp Immunogeniczny polipeptyd, polinukleotyd, polipeptyd, kompozycja farmaceutyczna, wektor ekspresji, kompozycja szczepionki, polipeptyd do stosowania w leczeniu lub zapobieganiu infekcjom Mycobacterium tuberculosis, polinukleotyd do stosowania w leczeniu lub zapobieganiu infekcjom Mycobacterium tuberculosis i sposób wytwarzania polipeptydu
GB2336310B (en) 1998-04-14 2003-09-10 Stowic Resources Ltd Method of manufacturing transdermal patches
AU3560399A (en) 1998-04-15 1999-11-01 Ludwig Institute For Cancer Research Tumor associated nucleic acids and uses therefor
US6322532B1 (en) 1998-06-24 2001-11-27 3M Innovative Properties Company Sonophoresis method and apparatus
HUP0203035A3 (en) 1998-07-14 2007-12-28 Corixa Corp Compositions and methods for therapy and diagnosis of prostate cancer
US6110929A (en) 1998-07-28 2000-08-29 3M Innovative Properties Company Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof
PT1187629E (pt) 1999-04-19 2005-02-28 Glaxosmithkline Biolog Sa Composicao adjuvante que compreende saponina e um oligonucleotido imunoestimulador
US6685699B1 (en) 1999-06-09 2004-02-03 Spectrx, Inc. Self-removing energy absorbing structure for thermal tissue ablation
JP4162813B2 (ja) 1999-10-28 2008-10-08 久光製薬株式会社 イオントフォレーシス装置
US6974588B1 (en) 1999-12-07 2005-12-13 Elan Pharma International Limited Transdermal patch for delivering volatile liquid drugs
US6908453B2 (en) 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US6676961B1 (en) 2002-03-06 2004-01-13 Automated Carrier Technologies, Inc. Transdermal patch assembly
US7018345B2 (en) 2002-12-06 2006-03-28 Hisamitsu Pharmaceutical Co., Inc. Iontophoresis system
KR20060120069A (ko) 2003-10-03 2006-11-24 쓰리엠 이노베이티브 프로퍼티즈 컴파니 피라졸로피리딘 및 그의 유사체
DE102005032175A1 (de) 2005-07-09 2007-01-18 Krones Ag Behälter-Behandlungsmaschine und Verfahren zum Laden und Entladen einer Behälter-Behandlungsmaschine
EP1611926B1 (de) 2005-07-19 2008-01-16 Gebrüder Holzapfel GmbH & Co. KG Auftriebshilfe
WO2007117680A2 (en) * 2006-04-06 2007-10-18 The Johns Hopkins University Methods and compositions for treating bacterial infection
PL2068918T5 (pl) * 2006-09-26 2024-12-02 Access To Advanced Health Institute Kompozycja szczepionki zawierająca syntetyczny adiuwant
CN101790380B (zh) * 2007-02-07 2013-07-10 加利福尼亚大学董事会 合成tlr激动剂的缀合物及其应用
BRPI0809926B8 (pt) 2007-04-04 2021-05-25 Infectious Disease Res Inst composição que compreende antígenos de mycobacterium tuberculosis, polipeptídeo de fusão isolado, polinucleotídeo isolado que codifica o dito polipeptídeo e uso da dita composição para estimular uma resposta imune protetora
US8793881B2 (en) 2008-08-15 2014-08-05 Stanley Black & Decker, Inc. Utility knife with blade lock
MX2011002267A (es) * 2008-08-28 2011-03-30 Glaxosmithkline Biolog Sa Vacuna.
PE20110992A1 (es) * 2009-02-17 2012-02-12 Glaxosmithkline Biolog Sa Composicion inmunogenica que comprende un antigeno del virus del dengue
CA2764374C (en) 2009-06-05 2019-11-19 Infectious Disease Research Institute Synthetic glucopyranosyl lipid adjuvants
WO2010143971A2 (en) * 2009-06-08 2010-12-16 Epitarget As Lipophilic drug carrier
TWI397428B (zh) * 2009-12-29 2013-06-01 財團法人工業技術研究院 標的第四介白素受體之傳輸系統
US20120014866A1 (en) 2010-07-15 2012-01-19 Ivor Bull Copper Containing ZSM-34, OFF And/Or ERI Zeolitic Material For Selective Reduction Of NOx
US9242980B2 (en) * 2010-08-17 2016-01-26 3M Innovative Properties Company Lipidated immune response modifier compound compositions, formulations, and methods
LT4226941T (lt) * 2010-08-31 2025-01-10 Glaxosmithkline Biologicals Sa Pegilintos liposomos, skirtos imunogeną koduojančios rnr pristatymui
CN113876945A (zh) * 2011-10-06 2022-01-04 免疫疫苗技术有限公司 包括激活或增加tlr2活性的佐剂的脂质体组合物及其应用
CN104023793B (zh) 2011-10-31 2017-11-24 马林克罗特有限公司 用于治疗癌症的联合脂质体组合物
EP2787977A4 (en) * 2011-12-09 2015-05-06 Univ California LIPOSOMAL ACTIVE INVERTING
ES2729967T3 (es) 2012-02-07 2019-11-07 Infectious Disease Res Inst Formulaciones de adyuvante mejoradas que comprenden agonistas de TLR4 y métodos para usar las mismas
CA2869748C (en) * 2012-04-12 2017-10-24 Yale University Vehicles for controlled delivery of different pharmaceutical agents
WO2013188699A1 (en) 2012-06-13 2013-12-19 Incytu, Inc. Compositions, methods and devices for activating an immune response
US10722569B2 (en) * 2012-07-05 2020-07-28 Children's Medical Center Corporation Bacterial biofilm matrix as a platform for protein delivery
CA2879356A1 (en) 2012-07-26 2014-01-30 National Oilwell Varco, L.P. Telescoping core barrel
US8638146B1 (en) 2012-07-31 2014-01-28 Cambridge Silicon Radio Limited Dual mode phase detection
US10039716B2 (en) * 2013-03-13 2018-08-07 Mallinckrodt Llc Liposomal cisplatin compositions for cancer therapy
ES2738582T3 (es) * 2014-02-14 2020-01-23 Immune Design Corp Inmunoterapia del cáncer a través de combinación de inmunoestimulación local y sistémica
EP3116479A1 (en) * 2014-03-12 2017-01-18 GlaxoSmithKline Biologicals S.A. Liposomal compositions for mucosal delivery
CN105534908B (zh) * 2016-01-15 2018-12-14 徐州医学院 一种包载核酸药物的具缺氧响应能力和放疗增敏功能脂质体
WO2017200957A1 (en) * 2016-05-16 2017-11-23 Infectious Disease Research Institute Pegylated liposomes and methods of use

Similar Documents

Publication Publication Date Title
JP2019518739A5 (https=)
Tretiakova et al. Liposomes as adjuvants and vaccine delivery systems
Pedersen et al. Immunocorrelates of CAF family adjuvants
Tandrup Schmidt et al. Liposome-based adjuvants for subunit vaccines: formulation strategies for subunit antigens and immunostimulators
US12220484B2 (en) Stable formulations of lipids and liposomes
Marasini et al. Liposomes as a vaccine delivery system
Davidsen et al. Characterization of cationic liposomes based on dimethyldioctadecylammonium and synthetic cord factor from M. tuberculosis (trehalose 6, 6′-dibehenate)—a novel adjuvant inducing both strong CMI and antibody responses
JP2026001042A (ja) ポリサルコシンを含むｒｎａ粒子
Kersten et al. Liposomes and ISCOMS
EP3964200A1 (en) Compositions and methods for delivery of therapeutic agents
JP5836394B2 (ja) 陽イオン性脂質を含む陰イオン性薬物伝達体およびその製造方法
Obeid et al. Examination of the effect of niosome preparation methods in encapsulating model antigens on the vesicle characteristics and their ability to induce immune responses
Liu et al. A novel liposome adjuvant DPC mediates Mycobacterium tuberculosis subunit vaccine well to induce cell-mediated immunity and high protective efficacy in mice
US4117113A (en) Immunological preparations
FR2726764A1 (fr) Adjuvant pour composition vaccinale
WO2017147691A1 (en) Orally administrable composition
CN115335084A (zh) 包含聚肌氨酸的rna颗粒
JP2020526530A5 (https=)
JP2017507968A (ja) 粘膜送達用のリポソーム組成物
Soni et al. The sixth revolution in pediatric vaccinology: immunoengineering and delivery systems
JP2023500921A (ja) 免疫誘導用ポリマーナノ粒子組成物及びその製造方法
WO2024209013A1 (en) Lipid nanoparticle compositions
Porte et al. A molecular view of lipid nanoparticles: insights into their morphology and structural plasticity
Nielsen et al. ISCOMs as a vaccine delivery system
RU2018137866A (ru) Пегилированные липосомы и способы их применения