JP2019518739A5 - - Google Patents

Download PDF

Info

Publication number
JP2019518739A5
JP2019518739A5 JP2018559785A JP2018559785A JP2019518739A5 JP 2019518739 A5 JP2019518739 A5 JP 2019518739A5 JP 2018559785 A JP2018559785 A JP 2018559785A JP 2018559785 A JP2018559785 A JP 2018559785A JP 2019518739 A5 JP2019518739 A5 JP 2019518739A5
Authority
JP
Japan
Prior art keywords
liposome
lipid
peg
mol
pegylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018559785A
Other languages
English (en)
Japanese (ja)
Other versions
JP7195147B2 (ja
JP2019518739A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/032756 external-priority patent/WO2017200957A1/en
Publication of JP2019518739A publication Critical patent/JP2019518739A/ja
Publication of JP2019518739A5 publication Critical patent/JP2019518739A5/ja
Priority to JP2022143788A priority Critical patent/JP2022177112A/ja
Application granted granted Critical
Publication of JP7195147B2 publication Critical patent/JP7195147B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018559785A 2016-05-16 2017-05-15 Peg化リポソームおよび使用方法 Active JP7195147B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022143788A JP2022177112A (ja) 2016-05-16 2022-09-09 Peg化リポソームおよび使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662337328P 2016-05-16 2016-05-16
US62/337,328 2016-05-16
PCT/US2017/032756 WO2017200957A1 (en) 2016-05-16 2017-05-15 Pegylated liposomes and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022143788A Division JP2022177112A (ja) 2016-05-16 2022-09-09 Peg化リポソームおよび使用方法

Publications (3)

Publication Number Publication Date
JP2019518739A JP2019518739A (ja) 2019-07-04
JP2019518739A5 true JP2019518739A5 (https=) 2020-06-25
JP7195147B2 JP7195147B2 (ja) 2022-12-23

Family

ID=58794159

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018559785A Active JP7195147B2 (ja) 2016-05-16 2017-05-15 Peg化リポソームおよび使用方法
JP2022143788A Pending JP2022177112A (ja) 2016-05-16 2022-09-09 Peg化リポソームおよび使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022143788A Pending JP2022177112A (ja) 2016-05-16 2022-09-09 Peg化リポソームおよび使用方法

Country Status (11)

Country Link
US (3) US11266602B2 (https=)
EP (1) EP3458028A1 (https=)
JP (2) JP7195147B2 (https=)
KR (1) KR102483033B1 (https=)
CN (1) CN109562057A (https=)
AU (2) AU2017268175B2 (https=)
BR (1) BR112018073676B1 (https=)
IL (3) IL313085B2 (https=)
MX (1) MX2018013640A (https=)
WO (1) WO2017200957A1 (https=)
ZA (1) ZA201807128B (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11266602B2 (en) 2016-05-16 2022-03-08 Infectious Disease Research Institute PEGylated liposomes and methods of use
EP3630076A1 (en) 2017-05-30 2020-04-08 GlaxoSmithKline Biologicals SA Methods for manufacturing a liposome encapsulated rna
CN107998070A (zh) * 2017-12-12 2018-05-08 南京中医药大学 一种复合磷脂传递体及其在制备经皮给药制剂中的应用
WO2020109365A1 (en) * 2018-11-29 2020-06-04 Glaxosmithkline Biologicals Sa Methods for manufacturing an adjuvant
US10765633B2 (en) * 2018-12-17 2020-09-08 Eisai R&D Management Co., Ltd Formulation comprising liposomes
CN110151702A (zh) * 2019-06-24 2019-08-23 昆明医科大学 聚乙二醇修饰流感疫苗脂质体及其制备方法
US11679163B2 (en) 2019-09-20 2023-06-20 Hdt Bio Corp. Compositions and methods for delivery of RNA
KR102328531B1 (ko) * 2020-01-23 2021-11-17 서울대학교산학협력단 체내 면역 세포 표적 황화수소 공여체 담지 리포좀을 포함하는 면역질환 치료 또는 예방용 약학 조성물
CA3172489A1 (en) 2020-03-23 2021-09-30 Amit KHANDHAR Nanoemulsion compositions and methods for delivery of nra
JP2023535405A (ja) * 2020-07-22 2023-08-17 ユニバーシティー オブ ヒューストン システム 呼吸器疾患に関連する状態の処置および防止
CN117120087A (zh) 2020-12-23 2023-11-24 高级健康研究所 茄尼醇疫苗助剂及其制备方法
US20240180834A1 (en) * 2021-02-26 2024-06-06 Univesity Of Virginia Patent Foundation Development of covid-19 vaccine using a dual tlr ligand liposome adjuvant
WO2022192674A1 (en) * 2021-03-11 2022-09-15 The Trustees Of The University Of Pennsylvania Targeted therapeutic lipid nanoparticles and methods of use
KR102682082B1 (ko) * 2021-06-01 2024-07-05 서울대학교산학협력단 리포좀 및 이를 포함하는 암 방사선 치료용 약학 조성물
JP2024535354A (ja) 2021-09-22 2024-09-30 エイチディーティー バイオ コーポレーション がん治療組成物およびその使用
EP4405372A4 (en) 2021-09-22 2026-01-14 Hdt Bio Corp SARS-CoV-2 RNA VACCINE COMPOSITIONS AND METHODS OF USE
EP4404919A4 (en) 2021-09-22 2025-08-20 Hdt Bio Corp DRIED NANOPARTICLE COMPOSITIONS
KR20240096468A (ko) 2021-09-22 2024-06-26 에이치디티 바이오 코포레이션 감염병에 대한 rna 백신
EP4637712A1 (en) * 2022-12-19 2025-10-29 Newimmune II, LLC Nanoparticulate formulation
CN115737800B (zh) * 2023-01-09 2023-05-23 江苏瑞科生物技术股份有限公司 一种复合脂质体佐剂及其制备方法
WO2025245466A1 (en) * 2024-05-24 2025-11-27 Curevo, Inc. Immunogenic compositions for the prevention of herpes zoster
CN121533991A (zh) * 2026-01-20 2026-02-17 杭州英妙生物科技有限公司 靶向B细胞或靶向CD11b+细胞的纳米脂质体及其应用

Family Cites Families (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598122A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US4286592A (en) 1980-02-04 1981-09-01 Alza Corporation Therapeutic system for administering drugs to the skin
US4314557A (en) 1980-05-19 1982-02-09 Alza Corporation Dissolution controlled active agent dispenser
US4379454A (en) 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
US4436727A (en) 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
IL73534A (en) 1983-11-18 1990-12-23 Riker Laboratories Inc 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
US4568343A (en) 1984-10-09 1986-02-04 Alza Corporation Skin permeation enhancer compositions
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
FI861417A0 (fi) 1985-04-15 1986-04-01 Endotronics Inc Hepatitis b ytantigen framstaelld med rekombinant-dna-teknik, vaccin, diagnostiskt medel och cellinjer samt foerfaranden foer framstaellning daerav.
US4948587A (en) 1986-07-08 1990-08-14 Massachusetts Institute Of Technology Ultrasound enhancement of transbuccal drug delivery
US4767402A (en) 1986-07-08 1988-08-30 Massachusetts Institute Of Technology Ultrasound enhancement of transdermal drug delivery
US5075109A (en) 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
EP1088830A3 (en) 1987-06-22 2004-04-07 Medeva Holdings B.V. Hepatitis b surface antigen particles
US4780212A (en) 1987-07-31 1988-10-25 Massachusetts Institute Of Technology Ultrasound enchancement of membrane permeability
US4897268A (en) 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
GB2232892B (en) 1988-02-23 1991-07-24 John Mark Tucker Occlusive body for administering a physiologically active substance
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
GB8819209D0 (en) 1988-08-12 1988-09-14 Research Corp Ltd Polypeptide & dna encoding same
US4999403A (en) 1988-10-28 1991-03-12 Exxon Chemical Patents Inc. Graft polymers of functionalized ethylene-alpha-olefin copolymer with polypropylene, methods of preparation, and use in polypropylene compositions
RU2121481C1 (ru) 1988-12-16 1998-11-10 Де Стат Дер Недерланден Вертегенвордигд Дор де Министр Ван Велзейн, Волксгезондхейд эн Кюлтюр Модифицированный пневмолизин, рекомбинантная плазмида, способ получения модифицированного пневмолизина, вакцина
DK0414374T3 (da) 1989-07-25 1998-03-09 Smithkline Beecham Biolog Hidtil ukendte antigener og fremgangsmåder til fremstilling deraf
US5256643A (en) 1990-05-29 1993-10-26 The Government Of The United States Human cripto protein
GB9106048D0 (en) 1991-03-21 1991-05-08 Smithkline Beecham Biolog Vaccines
DE122007000016I1 (de) 1991-07-19 2007-05-24 Univ Queensland Impfstoffe gegen Papillomavirus
US5464387A (en) 1991-07-24 1995-11-07 Alza Corporation Transdermal delivery device
ATE177755T1 (de) 1991-11-16 1999-04-15 Smithkline Beecham Biolog Hybrides protein zwischen cs aus plasmodium und hbsag
DE122007000099I1 (de) 1992-06-25 2008-03-27 Papillomavirus vakzine
US5786148A (en) 1996-11-05 1998-07-28 Incyte Pharmaceuticals, Inc. Polynucleotides encoding a novel prostate-specific kallikrein
US5437951A (en) 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
DE69434383T2 (de) 1993-03-09 2005-11-24 The University Of Rochester Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen
EP0708772B1 (en) 1993-07-15 2000-08-23 Minnesota Mining And Manufacturing Company IMIDAZO [4,5-c]PYRIDIN-4-AMINES
DE69433695T2 (de) 1993-11-02 2004-08-12 Matsushita Electric Industrial Co., Ltd., Kadoma Halbleiterbauelement mit Aggregat von Mikro-Nadeln aus Halbleitermaterial
US5458140A (en) 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
US5885211A (en) 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
US5814599A (en) 1995-08-04 1998-09-29 Massachusetts Insitiute Of Technology Transdermal delivery of encapsulated drugs
US5688506A (en) 1994-01-27 1997-11-18 Aphton Corp. Immunogens against gonadotropin releasing hormone
US5457041A (en) 1994-03-25 1995-10-10 Science Applications International Corporation Needle array and method of introducing biological substances into living cells using the needle array
US5591139A (en) 1994-06-06 1997-01-07 The Regents Of The University Of California IC-processed microneedles
WO1996011272A2 (de) 1994-10-07 1996-04-18 Medigene Gesellschaft Für Molekularbiologische Diagnostik, Theraphie Und Technologie Mbh Papillomavirusähnliche partikel, fusionsproteine sowie verfahren zu deren herstellung
US5955087A (en) 1995-02-24 1999-09-21 Cantab Pharmaceuticals Research Limited Polypeptides useful as immunotherapeutic agents and methods of polypeptide preparation
US5843464A (en) 1995-06-02 1998-12-01 The Ohio State University Synthetic chimeric fimbrin peptides
US5981215A (en) 1995-06-06 1999-11-09 Human Genome Sciences, Inc. Human criptin growth factor
US5618275A (en) 1995-10-27 1997-04-08 Sonex International Corporation Ultrasonic method and apparatus for cosmetic and dermatological applications
US5656016A (en) 1996-03-18 1997-08-12 Abbott Laboratories Sonophoretic drug delivery system
US5955306A (en) 1996-09-17 1999-09-21 Millenium Pharmaceuticals, Inc. Genes encoding proteins that interact with the tub protein
US7033598B2 (en) 1996-11-19 2006-04-25 Intrabrain International N.V. Methods and apparatus for enhanced and controlled delivery of a biologically active agent into the central nervous system of a mammal
US5840871A (en) 1997-01-29 1998-11-24 Incyte Pharmaceuticals, Inc. Prostate-associated kallikrein
WO1998037418A2 (en) 1997-02-25 1998-08-27 Corixa Corporation Compounds for immunodiagnosis of prostate cancer and methods for their use
JP2001510031A (ja) 1997-07-21 2001-07-31 ノース・アメリカン・ヴァクシン・インコーポレーテッド ワクチンとしての修飾された免疫原ニューモリシン組成物
GB9717953D0 (en) 1997-08-22 1997-10-29 Smithkline Beecham Biolog Vaccine
US7459524B1 (en) 1997-10-02 2008-12-02 Emergent Product Development Gaithersburg Inc. Chlamydia protein, sequence and uses thereof
KR100735651B1 (ko) 1997-11-28 2007-07-06 세로노 제네틱스 인스티튜트 에스.에이. 클라미디아 트라코마티스 게놈 서열과 폴리펩티드, 이의단편 및 이의 용도, 특히, 감염의 진단, 예방 및 치료 용도
UA67760C2 (uk) 1997-12-11 2004-07-15 Міннесота Майнінг Енд Мануфакчурінг Компані Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки
PT1053325E (pt) 1998-02-05 2006-05-31 Glaxosmithkline Biolog Sa Derivados de antigenios associados a tumores da familia mage e, sequencias de acidos nucleicos que os codificam, utilizados para a preparacao de proteinas de fusao e de composicoes para vacinacao.
WO1999051748A2 (en) 1998-04-07 1999-10-14 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
GB2336310B (en) 1998-04-14 2003-09-10 Stowic Resources Ltd Method of manufacturing transdermal patches
JP2002511266A (ja) 1998-04-15 2002-04-16 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ 腫瘍関連核酸及びその使用
US6322532B1 (en) 1998-06-24 2001-11-27 3M Innovative Properties Company Sonophoresis method and apparatus
CN100419079C (zh) 1998-07-14 2008-09-17 科里克萨有限公司 用于治疗和诊断前列腺癌的组合物和方法
US6110929A (en) 1998-07-28 2000-08-29 3M Innovative Properties Company Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof
DE60014076T2 (de) 1999-04-19 2005-10-13 Glaxosmithkline Biologicals S.A. Adjuvans-zusammensetzung, enthaltend saponin und ein immunstimulatorisches oligonukleotid
US6685699B1 (en) 1999-06-09 2004-02-03 Spectrx, Inc. Self-removing energy absorbing structure for thermal tissue ablation
JP4162813B2 (ja) 1999-10-28 2008-10-08 久光製薬株式会社 イオントフォレーシス装置
US6974588B1 (en) 1999-12-07 2005-12-13 Elan Pharma International Limited Transdermal patch for delivering volatile liquid drugs
US6908453B2 (en) 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US6676961B1 (en) 2002-03-06 2004-01-13 Automated Carrier Technologies, Inc. Transdermal patch assembly
US7018345B2 (en) 2002-12-06 2006-03-28 Hisamitsu Pharmaceutical Co., Inc. Iontophoresis system
TW200526656A (en) 2003-10-03 2005-08-16 3M Innovative Properties Co Pyrazolopyridines and analogs thereof
DE102005032175A1 (de) 2005-07-09 2007-01-18 Krones Ag Behälter-Behandlungsmaschine und Verfahren zum Laden und Entladen einer Behälter-Behandlungsmaschine
EP1611926B1 (de) 2005-07-19 2008-01-16 Gebrüder Holzapfel GmbH & Co. KG Auftriebshilfe
US9333250B2 (en) * 2006-04-06 2016-05-10 The Johns Hopkins University Methods and compositions for treating bacterial infection
PT2468300T (pt) * 2006-09-26 2018-01-30 Infectious Disease Res Inst Composição para vacina contendo adjuvante sintético
ES2552471T3 (es) * 2007-02-07 2015-11-30 The Regents Of The University Of California Conjugados de agonistas de TLR sintéticos y usos de los mismos
ES2621211T3 (es) 2007-04-04 2017-07-03 Infectious Disease Research Institute Composiciones inmunogénicas que comprenden polipéptidos de mycobacterium tuberculosis y fusiones de los mismos
US8793881B2 (en) 2008-08-15 2014-08-05 Stanley Black & Decker, Inc. Utility knife with blade lock
CA2734950A1 (en) * 2008-08-28 2010-03-04 Glaxosmithkline Biologicals S.A. Vaccine
AR075437A1 (es) * 2009-02-17 2011-03-30 Glaxosmithkline Biolog Sa Composicion inmunogenica que comprende al menos un antigeno del virus del dengue inactivado y un adyuvante sin aluminio, metodo para producir dicha vacuna y su uso para preparar un medicamento
CN102481312B (zh) 2009-06-05 2015-07-15 传染性疾病研究院 合成的吡喃葡萄糖脂佐剂
EP2440182A2 (en) * 2009-06-08 2012-04-18 Epitarget AS Lipophilic drug carrier
TWI397428B (zh) 2009-12-29 2013-06-01 財團法人工業技術研究院 標的第四介白素受體之傳輸系統
US20120014866A1 (en) 2010-07-15 2012-01-19 Ivor Bull Copper Containing ZSM-34, OFF And/Or ERI Zeolitic Material For Selective Reduction Of NOx
ES2617451T3 (es) 2010-08-17 2017-06-19 3M Innovative Properties Company Composiciones lipidadas de compuestos modificadores de la respuesta inmunitaria, formulaciones, y métodos
PT3970742T (pt) * 2010-08-31 2022-06-27 Glaxosmithkline Biologicals Sa Lipossomas peguilados para entrega de arn codificador de imunogénio
JP6240077B2 (ja) * 2011-10-06 2017-11-29 イムノバクシーン・テクノロジーズ・インコーポレイテッドImmunovaccine Technologies Inc. Tlr2を活性化するか、またはその活性を増加させるアジュバントを含むリポソーム組成物およびその使用
WO2013066903A1 (en) 2011-10-31 2013-05-10 Mallinckrodt Llc Combinational liposome compositions for cancer therapy
WO2013086526A1 (en) * 2011-12-09 2013-06-13 The Regents Of The University Of California Liposomal drug encapsulation
PL2811981T3 (pl) 2012-02-07 2019-09-30 Infectious Disease Research Institute Ulepszone formulacje adiuwantowe zawierające agonistę TLR4 oraz sposoby ich zastosowania
US9603800B2 (en) * 2012-04-12 2017-03-28 Yale University Methods of treating inflammatory and autoimmune diseases and disorders using nanolipogels
WO2013188699A1 (en) 2012-06-13 2013-12-19 Incytu, Inc. Compositions, methods and devices for activating an immune response
US10722569B2 (en) * 2012-07-05 2020-07-28 Children's Medical Center Corporation Bacterial biofilm matrix as a platform for protein delivery
CA2879356A1 (en) 2012-07-26 2014-01-30 National Oilwell Varco, L.P. Telescoping core barrel
US8638146B1 (en) 2012-07-31 2014-01-28 Cambridge Silicon Radio Limited Dual mode phase detection
BR112015022415A2 (pt) * 2013-03-13 2017-07-18 Mallinckrodt Llc composições de cisplatina lipossômica para terapia contra câncer
CA2939093A1 (en) * 2014-02-14 2015-08-20 Immune Design Corp. Immunotherapy of cancer through combination of local and systemic immune stimulation
KR20160132088A (ko) * 2014-03-12 2016-11-16 글락소스미스클라인 바이오로지칼즈 에스.에이. 점막 전달용 리포솜 조성물
CN105534908B (zh) * 2016-01-15 2018-12-14 徐州医学院 一种包载核酸药物的具缺氧响应能力和放疗增敏功能脂质体
US11266602B2 (en) * 2016-05-16 2022-03-08 Infectious Disease Research Institute PEGylated liposomes and methods of use

Similar Documents

Publication Publication Date Title
JP2019518739A5 (https=)
Tretiakova et al. Liposomes as adjuvants and vaccine delivery systems
Pedersen et al. Immunocorrelates of CAF family adjuvants
Tandrup Schmidt et al. Liposome-based adjuvants for subunit vaccines: formulation strategies for subunit antigens and immunostimulators
US12220484B2 (en) Stable formulations of lipids and liposomes
Marasini et al. Liposomes as a vaccine delivery system
JP2026001042A (ja) ポリサルコシンを含むrna粒子
Kersten et al. Liposomes and ISCOMS
EP3964200A1 (en) Compositions and methods for delivery of therapeutic agents
CN103476431B (zh) 包含阳离子脂质的用于带负电荷的药物的载体及其制备方法
Obeid et al. Examination of the effect of niosome preparation methods in encapsulating model antigens on the vesicle characteristics and their ability to induce immune responses
Liu et al. A novel liposome adjuvant DPC mediates Mycobacterium tuberculosis subunit vaccine well to induce cell-mediated immunity and high protective efficacy in mice
FR2726764A1 (fr) Adjuvant pour composition vaccinale
EP3423037A1 (en) Orally administrable composition
CN115335084A (zh) 包含聚肌氨酸的rna颗粒
JP2020526530A5 (https=)
KR20160132088A (ko) 점막 전달용 리포솜 조성물
Soni et al. The sixth revolution in pediatric vaccinology: immunoengineering and delivery systems
JP2023500921A (ja) 免疫誘導用ポリマーナノ粒子組成物及びその製造方法
EP4687853A1 (en) Lipid nanoparticle compositions
Nielsen et al. ISCOMs as a vaccine delivery system
RU2018137866A (ru) Пегилированные липосомы и способы их применения
Myschik et al. Immunostimulatory lipid implants containing Quil-A and DC-cholesterol
HRP20230985T1 (hr) Farmaceutske formulacije pegiliranih liposoma i faktora koagulacije krvi
JP2018070576A (ja) CD1dリガンドとがん抗原を含有するポリエチレングリコール(PEG)修飾の中性リポソームを有効成分とする抗がん剤組成物