JP2019518022A5 - - Google Patents
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- Publication number
- JP2019518022A5 JP2019518022A5 JP2018562567A JP2018562567A JP2019518022A5 JP 2019518022 A5 JP2019518022 A5 JP 2019518022A5 JP 2018562567 A JP2018562567 A JP 2018562567A JP 2018562567 A JP2018562567 A JP 2018562567A JP 2019518022 A5 JP2019518022 A5 JP 2019518022A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- intrahepatic cholestasis
- ceradelpar
- amount
- day
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662343688P | 2016-05-31 | 2016-05-31 | |
| US62/343,688 | 2016-05-31 | ||
| PCT/US2017/029620 WO2017209865A1 (en) | 2016-05-31 | 2017-04-26 | Treatment of intrahepatic cholestatic diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019518022A JP2019518022A (ja) | 2019-06-27 |
| JP2019518022A5 true JP2019518022A5 (enExample) | 2020-05-21 |
| JP7079735B2 JP7079735B2 (ja) | 2022-06-02 |
Family
ID=58699276
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018562567A Active JP7079735B2 (ja) | 2016-05-31 | 2017-04-26 | 肝内胆汁うっ滞性疾患の処置 |
Country Status (27)
| Country | Link |
|---|---|
| US (5) | US10272058B2 (enExample) |
| EP (1) | EP3463328B1 (enExample) |
| JP (1) | JP7079735B2 (enExample) |
| KR (1) | KR102408288B1 (enExample) |
| CN (2) | CN121466055A (enExample) |
| AU (1) | AU2017274293B2 (enExample) |
| BR (1) | BR112018074147A2 (enExample) |
| CA (1) | CA3024155C (enExample) |
| CY (1) | CY1125465T1 (enExample) |
| DK (1) | DK3463328T3 (enExample) |
| ES (1) | ES2921230T3 (enExample) |
| HR (1) | HRP20220903T1 (enExample) |
| HU (1) | HUE059838T2 (enExample) |
| IL (1) | IL263372B2 (enExample) |
| LT (1) | LT3463328T (enExample) |
| MX (1) | MX390417B (enExample) |
| NZ (1) | NZ748721A (enExample) |
| PL (1) | PL3463328T3 (enExample) |
| PT (1) | PT3463328T (enExample) |
| RS (1) | RS63345B1 (enExample) |
| RU (1) | RU2765460C2 (enExample) |
| SG (1) | SG11201810123SA (enExample) |
| SI (1) | SI3463328T1 (enExample) |
| SM (1) | SMT202200471T1 (enExample) |
| UA (1) | UA122719C2 (enExample) |
| WO (1) | WO2017209865A1 (enExample) |
| ZA (1) | ZA201808360B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10272058B2 (en) | 2014-03-20 | 2019-04-30 | Cymabay Therapeutics, Inc. | Treatment of intrahepatic cholestatic diseases |
| DK3119384T3 (en) | 2014-03-20 | 2018-12-03 | Cymabay Therapeutics Inc | TREATMENT OF INTRAHEPATHIC COLESTASTIC DISEASES |
| US10512622B2 (en) | 2017-07-14 | 2019-12-24 | Cymabay Therapeutics, Inc. | Treatment of intrahepatic cholestatic diseases |
| KR20210092754A (ko) * | 2018-11-16 | 2021-07-26 | 사이머베이 쎄라퓨틱스, 인코퍼레이티드 | Nafld 및 nash의 병용 치료 |
| SMT202400302T1 (it) * | 2021-02-01 | 2024-09-16 | Cymabay Therapeutics Inc | Trattamento di colangiopatie con seladelpar |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7101993B1 (en) | 1990-01-11 | 2006-09-05 | Isis Pharmaceuticals, Inc. | Oligonucleotides containing 2′-O-modified purines |
| US7015315B1 (en) | 1991-12-24 | 2006-03-21 | Isis Pharmaceuticals, Inc. | Gapped oligonucleotides |
| US5739135A (en) | 1993-09-03 | 1998-04-14 | Bristol-Myers Squibb Company | Inhibitors of microsomal triglyceride transfer protein and method |
| ATE327244T1 (de) | 1995-03-06 | 2006-06-15 | Isis Pharmaceuticals Inc | Verfahren zur synthese von 2'-0-substituierten pyrimidinen und oligomere davon |
| US6166197A (en) | 1995-03-06 | 2000-12-26 | Isis Pharmaceuticals, Inc. | Oligomeric compounds having pyrimidine nucleotide (S) with 2'and 5 substitutions |
| BR9707529A (pt) | 1996-02-14 | 2000-01-04 | Isis Pharmaceuticals Inc | Oligunucleotìdeo especificamente hibridizável com dna ou rna. |
| US5883109A (en) | 1996-07-24 | 1999-03-16 | Bristol-Myers Squibb Company | Method for lowering serum lipid levels employing an MTP inhibitor in combination with another cholesterol lowering drug |
| US6066653A (en) | 1997-01-17 | 2000-05-23 | Bristol-Myers Squibb Co. | Method of treating acid lipase deficiency diseases with an MTP inhibitor and cholesterol lowering drugs |
| US7407943B2 (en) | 2001-08-01 | 2008-08-05 | Isis Pharmaceuticals, Inc. | Antisense modulation of apolipoprotein B expression |
| US7511131B2 (en) | 2002-11-13 | 2009-03-31 | Genzyme Corporation | Antisense modulation of apolipoprotein B expression |
| US7981915B2 (en) | 2003-04-30 | 2011-07-19 | Beth Israel Deaconess Medical Center | Methods for modulating PPAR biological activity for the treatment of diseases caused by mutations in the CFTR gene |
| SI1667964T1 (sl) | 2003-09-19 | 2009-12-31 | Janssen Pharmaceutica Nv | 4-((fenoksialkil)tio)-fenoksiocetne kisline in analogi |
| CA2910191C (en) | 2004-03-05 | 2022-03-08 | The Trustees Of The Univeristy Of Pennsylvania | The use of mtp inhibitors for treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia while minimizing side effects |
| JO3006B1 (ar) | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
| KR20110091680A (ko) | 2008-10-17 | 2011-08-12 | 메타볼렉스, 인코포레이티드 | 작고 조밀한 ｌｄｌ 입자를 감소시키는 방법 |
| CN107233337A (zh) * | 2009-04-29 | 2017-10-10 | 阿马里纳药物爱尔兰有限公司 | 含有epa和心血管剂的药物组合物以及使用其的方法 |
| MA34097B1 (fr) | 2010-03-30 | 2013-03-05 | Novartis Ag | Utilisations d'inhibiteurs de dgat1 |
| JOP20200043A1 (ar) | 2011-05-10 | 2017-06-16 | Amgen Inc | طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول |
| US20160279085A1 (en) | 2013-11-20 | 2016-09-29 | Cymabay Therapeutics, Inc. | Treatment of Severe Hyperlipidemia |
| EA201691039A1 (ru) | 2013-11-20 | 2016-11-30 | Саймабэй Терапьютикс, Инк. | Лечение гомозиготной семейной гиперхолестеринемии |
| US10272058B2 (en) | 2014-03-20 | 2019-04-30 | Cymabay Therapeutics, Inc. | Treatment of intrahepatic cholestatic diseases |
| DK3119384T3 (en) | 2014-03-20 | 2018-12-03 | Cymabay Therapeutics Inc | TREATMENT OF INTRAHEPATHIC COLESTASTIC DISEASES |
| UA121208C2 (uk) | 2014-04-11 | 2020-04-27 | Сімабей Терапьютікс, Інк. | Лікування нажхп та насг |
| CN106470675A (zh) | 2014-06-26 | 2017-03-01 | 西玛贝医药公司 | 严重高甘油三酯血症的治疗 |
| US10512622B2 (en) | 2017-07-14 | 2019-12-24 | Cymabay Therapeutics, Inc. | Treatment of intrahepatic cholestatic diseases |
| LT3973959T (lt) | 2017-09-26 | 2025-01-10 | Cymabay Therapeutics, Inc. | Cholestazinio niežulio gydymas seladelparu |
| KR20210092754A (ko) | 2018-11-16 | 2021-07-26 | 사이머베이 쎄라퓨틱스, 인코퍼레이티드 | Nafld 및 nash의 병용 치료 |
| EP3880187A1 (en) | 2018-11-16 | 2021-09-22 | CymaBay Therapeutics, Inc. | Treatment of obesity and its complications |
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2017
- 2017-04-25 US US15/496,875 patent/US10272058B2/en active Active
- 2017-04-26 SG SG11201810123SA patent/SG11201810123SA/en unknown
- 2017-04-26 ES ES17722943T patent/ES2921230T3/es active Active
- 2017-04-26 SM SM20220471T patent/SMT202200471T1/it unknown
- 2017-04-26 UA UAA201811776A patent/UA122719C2/uk unknown
- 2017-04-26 AU AU2017274293A patent/AU2017274293B2/en active Active
- 2017-04-26 LT LTEPPCT/US2017/029620T patent/LT3463328T/lt unknown
- 2017-04-26 DK DK17722943.2T patent/DK3463328T3/da active
- 2017-04-26 MX MX2018014915A patent/MX390417B/es unknown
- 2017-04-26 CN CN202610013198.XA patent/CN121466055A/zh active Pending
- 2017-04-26 NZ NZ748721A patent/NZ748721A/en unknown
- 2017-04-26 PL PL17722943.2T patent/PL3463328T3/pl unknown
- 2017-04-26 CN CN201780033512.XA patent/CN109195594A/zh active Pending
- 2017-04-26 JP JP2018562567A patent/JP7079735B2/ja active Active
- 2017-04-26 HR HRP20220903TT patent/HRP20220903T1/hr unknown
- 2017-04-26 PT PT177229432T patent/PT3463328T/pt unknown
- 2017-04-26 KR KR1020187037704A patent/KR102408288B1/ko active Active
- 2017-04-26 CA CA3024155A patent/CA3024155C/en active Active
- 2017-04-26 EP EP17722943.2A patent/EP3463328B1/en active Active
- 2017-04-26 HU HUE17722943A patent/HUE059838T2/hu unknown
- 2017-04-26 RS RS20220620A patent/RS63345B1/sr unknown
- 2017-04-26 SI SI201731175T patent/SI3463328T1/sl unknown
- 2017-04-26 WO PCT/US2017/029620 patent/WO2017209865A1/en not_active Ceased
- 2017-04-26 BR BR112018074147-7A patent/BR112018074147A2/pt not_active Application Discontinuation
- 2017-04-26 RU RU2018146504A patent/RU2765460C2/ru active
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2018
- 2018-11-29 IL IL263372A patent/IL263372B2/en unknown
- 2018-12-11 ZA ZA2018/08360A patent/ZA201808360B/en unknown
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2019
- 2019-03-28 US US16/367,660 patent/US10478411B2/en active Active
- 2019-10-09 US US16/597,313 patent/US10813895B2/en active Active
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2020
- 2020-09-18 US US17/024,971 patent/US11000494B2/en active Active
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2021
- 2021-04-03 US US17/221,784 patent/US11596614B2/en active Active
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2022
- 2022-08-04 CY CY20221100534T patent/CY1125465T1/el unknown